吸着性藥品에 關한 硏究 : pH의 影響에 對하여

韓寬燮,金良培,朴洪球 서울대학교 1972 서울대학교 論文集 Vol.22 No.-

In the previous paper, authors compared the adsorptivity of single use with compounded use of adsorbents. As adsorbates, water-soluble indicators, i.e., Methylene blue, Gentiana violet, Congo red, were used. In this paper, authors tried to compare the adsorptivity of single use with compounded use in differentiating pH. The adsorptivity was evaluated by the determination of transmittance using spectrophotometer. As results, activated charcoal and Kaolin show desirable adsorptivity in compounded use than single use. However, the Korean clay doesn't show as Kaolin. By X-ray diffraction analysis and color reaction, the above Korean clay was similar to montmorillonite. Each compound doesn't show any elevation of adsorptivity in the alkaline. In acidie solution, Methylene blue showed increased adsorptivity but other compounds showed strong adsorptivity around neutral pH range.

Competition Responses of Populus alba Clone ‘Bolleana’ to red:far-red light

Bae,Han-hong,Kang,Ho-duck,Richard B,Hall 한국자원식물학회 2004 Plant Resources Vol.7 No.1

The reduced ratio of red:far-red (R:FR) light acts as a measure of the proximity of competitors and plants can detect the potentially competing neighbor plants by perceiving reflected R:FR signals and initiate the response of “shade avoidance” before actual shading occurs. The phytochrome system is responsible for monitoring the changes in the R:FR and initiating the shade avoidance response. The response to low R:FR ratio was studied in a white aspen Populus alba clone ‘Bolleana’ using two filter systems: a clear plastic filter system that allows a R:FR ratio less than 1.0 to pass from adjacent border plant reflection; and a special commercial plastic that blocks FR light and creates a R:FR ratio above 3.0. The reduced R:FR signals enhanced the stem elongation in response to competition at the expense of relative stem diameter growth. Trees grown inside clear chambers were 27 % taller than trees grown inside the FR-blocking filter chambers. Stem taper of clear chamber trees was 16% less than the FR-blocking filter trees. Low R:FR also induced 22% more stem dry weight and 13% greater petiole length per leaf compared to the FR-blocking filter trees. There were no statistically significant differences in leaf area, leaf number increment, and total dry weight between the two light filter treatments.

생산량을 고려한 부품-기계 셀 형성에서의 퍼지이론 이용

김홍배,김재한 慶星大學校 1994 論文集 Vol.15 No.2

This paper deals with Machine-Part Group Formation in Group Technology. In order to consider uncertainty and impreciseness in Machine-Part Group Formation, this paper introduces Fuzzy Theory. In this paper we consider production volume in determination of fuzzy similarity coefficient. Although there is no proper performance measure, Fuzzy similarity coefficient proposed in this paper consider production volume and the result of this study can applicable to real life cell formation.

3종 페라이트/고무 복합형 전파흡수체에 있어서 재료정수의 주파수 의존성

김철한,전홍배,유영준,사공건 東亞大學校 1999 東亞論叢 Vol.36 No.-

In this study, ferrite/rubber composite specimens have prepared by molding and curing the mixture of matrix silicon rubber and three kinds of filler particle Mn-Zn/Ni-Zn/Ni₂Y ferrite which are synthesized by the coprecipitation mehtod. The mixing ratio of three kinds of ferrite filler paticle gave variety to adjust the material constant of composite microwave absorbers. Material constants of composite specimens were calculated from the measured variables(s-parameter) over the frequency range from 1 to 12 GHz by means of Network Analyzer(HP8722D) with a co-axial type air line. The reflection loss was calculated from material constants on the impedance matching map utilizing simplex method. By chaging mixing ratio of three kinds of ferrite filler particle, the frequency range over than 20dB were relatively broaden and maximum reflection loss were remarkably reduced to others specimens excepted specimen D. Finally, it could make microwave absorber to be used for C-band frequency range.

소방시설 관리실태조사에 관한 연구 : 공동주택, 상가건축물, 사무소건축물

김홍배,한상민,이영재,조병선 한국화재소방학회 2001 한국화재소방학회논문지 Vol.15 No.3

현 사회는 안락과 안전을 중요시하고 있다. 그 중, 가장 중요한 부분의 한 부분이 각 건축물에 설치되어 있는 소방시설의 관리와 방화훈련이 얼마나 잘 관리되고 평소 훈련이 되어 있는가에 따라서 화재시에 인명과 재산상의 피해를 극소화 할 수 있다. 따라서, 본 연구에서는 공동주택, 상가건축물 및 사무소건축물 등의 소방시설의 점검실태를 설문ㆍ조사하였으며, 화재시에 대피훈련을 얼마나 숙지하고 있는가를 조사ㆍ분석함으로써 화재시 손실을 최소화 할 수 있는 방법과, 실질적인 점검 및 훈련방법을 제시한다. In a daily life these days, the safety and the comfort are considered very important. As the same as other areas, the good maintenance of fire protection systems and the fire drill plans in buildings can minimize the loss of human life and the property in case of fires. In this paper, a survey has been conducted to investigate the maintenance status of the fire protection systems of apartment buildings, shopping centers and office buildings. Both practical procedures for checking the systems and for fire drills and strategic plans to minimize the losses in case of fires are suggested by analyzing how well the occupants in the buildings acknowledge the evacuation drills when the fire occurs. Keywords : Fire protection system, Fire drill, Apartment buildings, Shopping center, Office building

대구지역 금호강 및 주요 지천 퇴적물의 시·공간적 독성변화

정홍배,문성환,정진애,김재현,박정규,배철한,황인영 한국환경독성학회 2001 환경독성보건학회지 Vol.16 No.4

1. 사전에 선정된 공통 조사 정점들 가운데 KㆍH4(금호대교)이후의 퇴적물 독성이 상부의 것보다 크게 나타났다. 즉, 정점 KH3과 KH4, 그리고 KH4와 KH5 사이에 독성물질 유입원이 있는 것으로 판단되었다. 2. 하천 퇴적물의 독성 수준에 영향을 주고 있는 물질의 종류와 배출원 파악이 필요하였다. 이러한 내용을 향후 계속적 연구 및 조사를 통하여 수행되어야 하는 과제라 사료된다. 3. 퇴적물 시료의 채취 시점에 따라서 동일 정점의 독성 변화가 심하였다. 유해화학물질에 의한 오염 수준과 하천 생태계의 영향을 예측하기 위해서는 하천 퇴적물을 대상으로 경시적으로 독성의 변화를 계속 관측하는 것이 필요하다고 판단되었다. In aqueous ecosystems, the level of toxicity is highly responsive dependant to multiple variables, including rainfall, sunlight, pH, adhesion, etc. Because Korea has particularly distinct wet and dry seasons, the toxicity of pollutants in rivers or streams is dependant on the sampling season and time. In order to examine the effects of rainfall on toxicity, sediment samples were collected from five sites along the Keumho river. It was found that Microlox toxicity levels were generally higher during the dry season than the wet season. It indicated that river pollutants are carried off more quickly by the water during the wet season. As a result, it was recommended that the point sources of pollutants of the Keumho river would be placed between KH3 (Paldalgyo) and KH4 (Keumhogyo), KH4 (Keumhogyo) and KH5 (Dasa).

모바일 로봇의 견실제어를 위한 제네틱 알고리즘 개발

김홍래,배길호,정경규,한성현 한국공작기계학회 2004 한국공작기계학회 춘계학술대회논문집 Vol.2004 No.-

This paper proposed trajectory tracking control of mobile robot. Trajectory tracking control scheme are real coding genetic-algorithm and back-propergation algorithm. Control scheme ability experience proposed simulation. Stable tracking control problem of mobile robots have been studied in recent years. These studies have guaranteed stability of controller, but the performance of transient state has not been guaranteed. In some situations, constant gain controller shows overshoots and oscillations. So we introduce better control scheme using Real coding Genetic Algorithm(RCGA) and neural network. Using RCGA, we can find proper gains in several situations and these gains are generalized by neural network. The generalization power of neural network will give proper gain in untrained situation. Performance of proposed controller will verify numerical simulations and the results show better performance than constant gain controller.

국내 하천 퇴적물 건강성평가를 위한 Microtox 독성시험 조건확립 연구

정홍배,박정규,문성환,류태권,김소정,배철한,황인영 한국환경독성학회 2001 환경독성보건학회지 Vol.16 No.4

1. 하천 퇴적물 공극수, 증류수 추출용액 및 유기용매 추출액을 pH6.0~6.5 범위로 조절한 후 Microtox 독성을 측정하는 것이 퇴적물내의 암모니아 독성이 배제된, 유해화학물질 오염에 의한 퇴적물 독성을 평가하는 방안임을 확인하였다. 2. 퇴적물에 대해 공극수, 증류수 추출물, 유기용매 추출물 구분하여 Microtox 독성을 구하는 것이 퇴적물 내 유해화학물질의 독성발현 특성을 예측할 수 있는 기법이라고 사료된다. 3. 조사정점 내 시료 채취 지점간 독성에 편차로 인하여, 동일 정점의 반경 50~100m 내에서 최소 4지점 이상의 퇴적물을 확보하는 것이 해당 정점의 독성 대표값을 산출할 수 있는 방안이 된다고 판단된다. 4. 한강수계인 남한강 지천인 복하천과 양화천, 금강수계인 청주 미호천, 대전 갑천, 낙동강수계인 대구 금호강, 영산강수계인 황룡강 그리고 익산 만경강을 대상으로 한 예비 조사한 결과, 집중연구대상 하천으로의 조건은 금호강이 가장 우수하였다. 5. 하천 퇴적물의 증류수 추출액과 유기용매 추출액의 Microtox 독성값 간의 상호 상관성이 높았다. 그러나, 농축 과정이 용이하므로 정점간 비교를 위한 독성 측정시 유기용매 추출액을 사용하는 것이 바람직하다고 사료되었다. Six rivers were selected as preliminary screening sites to determine the test conditions of Microtox in assessing the toxicity of the sediment. In addition, a pH range of 6.0--6.5 was established in testing pore water, aqueous extracts and organic extracts. Each extractable fraction of sediment showed different toxicities. Therefore, in order to properly examine the toxicity in the sediment, all extractable fractions of sediment samples needed to be tested with Microtox. Thus, sediment samples were additionally collected from at least 4 secondary sites within 50~100 m area of the primary sampling site to reduce any variation or deviation in toxicity assessment. From all sediment toxicity data that was collected from this study, it was concluded that the Keumho river was the most polluted with the highest sediment toxicity of all the rivers analyzed and needed further detailed research on its pollution problem.

결장 직장암 환자에서 근치적 절제술 후 혈청 CEA치의 변화에 대한 임상적 의의

김영훈,배병노,김기환,한세환,김홍주,김영덕,김홍용 대한대장항문학회 2003 Annals of Coloproctolgy Vol.19 No.6

Cytokine and Tumor Environments

Jin Tae Hong1*, Ju Kyung Song, Sun Mi Kwon, Byung Woo Ahn, Youngsoo Kim, Sang Bae Han 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.1

Cytokines are known to function as regulatory molecules that can be produced by virtually every nucleated cell type in the body, including lymphocytes, monocytes/macrophages, epithelial cells, fibroblasts, and many others. Cytokines include lymphocyte-derived factors (lymphokines), monocyte-derived factors (monokines), hematopoietic factors (colony-stimulating factors), connective tissue/growth factors, and chemotactic chemokines. Cytokines released in response to infection can affect tumor development in different ways. When exposed to infectious agents, cytokines are secreted by sentinel cells, such as macrophages and dendritic cells. These cytokines include interleukin 1 (IL-1) and tumor necrosis factor-α, as well as others, such as IL-6, IL-12, and IL-18. When released in sufficient quantities, these molecules can cause inflammation. Chronic inflammation is highly associated with tumor initiation, promotion, and progression. In this article, we review the roles and mechanisms of cytokines in tumor development.