미용업 종사자들의 피부, 호흡기 및 근골격계 자각증상에 관한 유병률

이종태,박봉진,엄상화,김성준,강동묵,손혜숙,정귀원,강민숙,박성희 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.3

Objectives: Present study was conducted to evaluate work-related symptom prevalence among hairdressers. Methods: Exposed group comprised 184 employee employed 73 hair salons in 6 district of Pusan city, and non-exposed group comprised 119 people living recent apartments. A trained interviewer interviewed them with organised questionnaire which included dermatologic, respiratory and musculo-skeletal symptoms. Results : Prevalence of hand eczema was 28.3% in exposed group, and 5.8% in non-exposed group. Adjusted odds ratio for age and atopy history was 4.30(2.34-7.93). Prevalence of respiratory symptom (coughing) in exposed group was 22.1%, and 9.4% for non-exposed group. Adjusted odds ratio for coughing which was adjusted for age, smoking and atopy history was 2.76(1.32∼5.78). Prevalences of musculo-skeletal symptoms among exposed group were neck(59.9%), shoulder(76.6%), upper back(41.2%), lower back(72.2%), arm and elbow(31.3%), wrist(44.2%), finger(35.0%), leg(71.1%). Adjusted Odds Ratios for musculo-skeletal symptoms which was adjusted for age were neck 2.13(1.29∼3.51), shoulder 2.52(1.50∼4.24), upper back 1.71(1.01∼2.88), lower back1.78(1.06∼2.99), arm and elbow 3.10(1.62∼5.94), wrist 2.09(1.23∼3.57), finger 4.83(2.41∼9.68), leg 3.46(2.07∼5.79). Conclusions : These results show that employees in hair salon are likely to have high risk for work-related dermatologic, respiratory and musculo-skeletal symptoms and diseases. Hence, prevention methods from those work-related diseases are required to be developed. Also, the scope of occupational and environmental medicine should be expanded to service area including hairdressers.

한국형 우울장애 약물치료 알고리듬 (Ⅳ) : 우울장애의 아형 및 부작용에 따른 항우울제의 선택과 여성우울장애에서의 치료전략

전현태,이상열,김원,민경준,박원명,서정석,석정호,송해철,전덕인,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

Objectives : In 2002, the Korean Medication Algorithm Project for Major depressive Disorder (KMAP-MD) was published, but there has been a need for a guideline about detailed issues of depressive disorder. We revised KMAP-MDD andreestablished Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) in 2006. Methods : A questionnaire had been developed by the executive committee for KMAP-DD. The review committee consisted of 101 experienced psychiatrists. From the total of 22 questions in the questionnaire, 7 questions were evaluated for these subjects . We classified the expert opinions to 3 categories according to its confidence interval; first, second and third line. Results : SSRI and venlafaxine were the first line antidepressants (AD) for atypical and melancholic depression. For dysthymic disorder and minor depressive disorder, SSRI was recommended as the first line medications. Only AD medications was a preferred initial strategy for treating premenstrual dysphoric disorder, mild to moderate and severe non-psychotic postpartum depression. In severe psychotic postpartum depression, combination therapy of AD and atypical antipsychotics was the treatment of choice. SSRI was preferred when considering sedation, anticholinergic and cardiovascular adverse effects. Also, experts recommended mirtazapine against gastrointestinal adverse effects and bupropion in avoiding sexual dysfunction. Conclusion : These results suggest that clinicians have to consider both clinical situations and drug adverse effects in the choice of antidepressant medications.

메틸렌 클로라이드에 의한 폐장염

장규진,박종태,,김은경,김병권,김해준 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Objectives: The authors report a case of pneumonitis caused by methylene chloride (MC). Methods: The patient was examined and diagnosed by clinical, radiologic, laboratorial and medical evaluation. The concentration of MC in the factory was measured to determine the exposure level. Results: The patient had an infiltration in chest X-ray, which underwent rapid relief of radiological finding, respiratory acidosis and hypoxemia in arterial blood gas analysis, and a ground-glass opacity in high resolution computerized tomography. MC was the only exposed chemical compound in this case. The concentration of MC was 39.9 ppm in the factory. Conclusions: We diagnosed this to be a case of pneumonitis by MC based on clinical laboratory findings, exposure history to MC and MC concentration in the factory.

미생물을 이용한 해조류의 가수분해 및 이용 : Ⅱ. 돌가사리, 톳 및 가시파래를 가수분해시키는 미생물군의 탐색 Ⅱ. Screening of Microfloras Involved in Hydrolysis of Seaweed Tenella, Seaweed Fusiforme and Green Laver

김해섭,배태진 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.3

해조류 조직을 가수분해시켜 기호성 및 응용성이 높은 액상원료로 가공하는 기술 개발의 일환으로 우선 자연계에 존재하는 미생물로서 산, 논, 밭, 해변 및 어판장에서 약 200종류의 미생물군 시료를 수집하여 해조의 조직파괴가 인정되는 8군의 미생물 시료를 사용하여 돌가사리, 톳 및 가시파래의 조직파괴와 가수 분해 가능성에대하여 검토하고, 추출액 중의 전당과 환원당을 측정하여 추출율과 분해율을 비교하였다. 그 결과 돌가사리, 톳 및 가시파래의 전당 추출량과 추출율은 각각 담수에서 채취한 미생물군 시료 (No. 27번), 부식한 식물에서 채취한 미생물군 시료 (No. 8번) 및 담수에서 채취한 미생물군 시료가 가장 높은 값을 나타내었고, 환원당의 추출량과 시료가 가장 높은 값을 나타내었고, 환원당의 추출량과 추출율에서는 각각 8번, 8번 및 27번 미생물 군 시료가 가장 높은 값을 나타내었다. 분해율은 전당의 추출율도 상당히 높으면서 환원당의 추출이 가장 높았던 실험구들이 각각의 해조에서 가장 높은 분해율을 나타내는 결과를 얻었다. 따라서 이들 자연계에서 채취한 미생물군 시료중에 해조 조체를 파괴시키고, 또한 해조에 다량 함유되어 있는 당을 비롯한 유용성분의 추출을 용이하게 하며, 해조를 가수분해시키는 효소를 가진 미생물이 존재할 것으로 판단되었으며, 또한 이들 미생물군에서 단일 또는 복합 해조가수분해 미생물 및 효소의 생산이 가능할 것으로 기대되었다. The purpose of this study is screening of microfloras involved in hydrolysis of seaweed tenella, seaweed fusiforme and green laver. This is a part of studies on the hydrolysis of seaweed using microorganisms. First, about two hundred microflora samples were obtained from mountain, rice field, dry field, sea, seaside and fish market in the vicinity of Yeosu. Thiry-three microflora samples were screened from the destruction of tissue in sea tangle and sea mustard . It was sufficient that results of the naked eye observation were obtained at eight microflora samples as a feces of bull, a decayed pine tree, a soil of dry field, the mud of the banks in a rice field, the water of a ditch in a rice field, the weed of the banks in a rice field, the water in a rice field and leaved in the air. Above all, extraction rate and contents of reducing sugar in extracts of seaweeds added a decayed pine tree (sample No. 8) and the water of a ditch in a rice field (sample No. 27) were showed high value. And the value of chemical analysis of the sample is much better in comparison with control. Accordingly the hydrolysis of seaweed using mcriorganisms in the inside of these microflora samples can be possible.

그람양성구균에 대한 Teicoplanin과 Vancomycin의 시험관내 항균력

최태열,김경숙,전용관,서일혜,김정욱,이웅수,안정열,김홍석,정재용,최효선,김덕언,유진우 대한감염학회 1994 감염 Vol.26 No.1

An increasing frequency of methicillin resistant S. aureus(MRSA), methicillin resistant coagulase negative staphylococci(MRCNS) and Enterococcal infection have been observed in recent years. Teicoplanin is a new glycopeptide antibiotic obstained from the Actinoplanes teicomycetius. The molecular structure and spectrum of antimicrobial activity of teicoplanin is simillar to those of vancomycin, and has been reported to have an excellent in vitro and in vivo effect against various gram-positive infections. Therefore, we evaluated the in vitor susceptibility of gram positive cocci, such as, S. aureus, coagulase negative Staphylococci(CNS), and Enterococci to teicoplanin and vancomycin. The total 253 strains consisted of MSSA(40), MRSA(53), MSCNS(47), MRCNS(48), and Enterococci(65). They were assayed by disc diffusion and agar dilution. During the study, 57% of S. aureus and 49% of CNS showed resistance to methicillin. The inhibitory diameter of teicoplanin was 15-20mm in MSSA, 12-19mm in MRSA, 13-24mm in MSCNS, 11-23mm in MRCNS, and 15-22mm in Enterococci respectively, and showed sensitivity in all but 8 strains(3.2%). The range of the minimum inhibitory concentration (MIC) of teicoplanin to MSSA, MRSA, MSCNS, MRCNS and Enterococci were 9.12-2.0㎍/ml, 0.25-2.0㎍/ml, & 0.25-32㎍/ml, 0.12-1.0㎍/ml respectively. One case of S. haemolyticus was resistant to teicoplanin (32㎍/ml) by the agar dilution method. Eight minor (3.2%) and one major(0.4%) error was observed when the MIC and disk diffusion data were correlated with teicoplanin. As for vancomycin the inhibitory diameter was 17-21mm in MSSA, 15-21mm in MRSA, 18-26mm in MSCNS, 18-25mm in MRCNS, and 16-22mm in Enterococci respectively. The range of the MIC of vancomycin to MSSA, MRSA, MSCNS, MRCNS, and Enterococci were 0.25-1.0㎍/ml, 0.25-4.0㎍/ml, 0.5-2.0㎍/ml and 0.5-2.0㎍/ml respectively. One minor error (0.4%) was seen with the vancomycin disk. The MIC90 of MSSA and MRSA exhibited the same results in teicoplanin (1.0㎍/ml, 1.0㎍/ml), and vancomycin(2.0㎍/ml, 2.0㎍/ml). MSCNS and MRCNS exhibited greater MIC90 with teicoplanin(4.0㎍/ml, 8.0㎍/ml) than vancomycin(2.0㎍/ml, 2.0㎍/ml). Incontrase Enterococci were more susceptible to teicoplanin(0.5㎍/ml) than to vancomucin (2.0㎍/ml). Results from this analysis indicated that both teicoplanin and vancomycin were very excellent for gram positive infections, especially those resistant to methicillin.

가토안의 Acid Phosphatase의 활성 및 분포

김태조,손해숙,송미영,이양진 曉星女子大學校 藥學大學 學生會 1990 曉星藥誌 Vol.5 No.-

Lysosomal enzyme activity of choroid, newrosensory retina, iris and ciliarybody, cornea and sclea of the rabbit eye was measured by acid phosphatase(ASPase)as enzyme maker. We reported lysosomal enzyme activity on retinal pigment epitherium in 1998. Distribution of ACPase in the tissues was carried out using Fukuzawa method and Kind-king method. Of the tissues of the rabbit eye the ACPase activity was highest in the choroid(28.6583±12.6920)by Kind-king method. The meurosensory retina(4.5433±2.2091), Iris & ciliary body(2.4138±0.8307), cornea(1.7223±0.6492)and sclea(0.9550±0.0646)also showed the specipic activity of enzyme.

일 농촌지역에서 발기부전의 유병률 및 상관 요인

홍진표,송해철,이무송,이창화,안준호,한오수,안태영,김성윤 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The purpose of this study was to investigate the prevalence of erectile dysfunction (ED) in a rural area of Korea and to examine the relationship between the prevalence and correlates of subjects. Method : This study was done as a part of the chronic disease survey of rural area by the Asan Foundation. Among 30 years or older population from Jung Eup, a rural area of Korea, 711 male subjects were sampled using a cluster probability sampling method. Trained interviewers visited and interviewed subjects aged 30 years or older with a structured interview. ED was categorized as 'none', 'mild', 'moderate', or 'severe' according to the ability to 'attain and/or maintain an erection satisfactory for sexual intercourse'. Response rate was 54.3% (N=386). Results : The age weighted prevalence of ED was 27.2% (minimal 14.1%, moderate 7.6%, severe 5.5%). Prevalence and severity increased with age. Liver disease and underweight were significantly (p<0.05) associated with ED. Smoking seemed to be correlated with ED, but did not reach statistically significant level. Conclusion : ED was highly prevalent in the rural community of Korea. Medical, sociodemographic, and lifestyle variables associated with ED may alert physicians to patients at risk for ED and offer insight to its etiology.

시각 특성을 고려한 웨이브릿 변환 비디오 압축

양해권,김진태 群山大學校 情報通信技術硏究所 1998 情報通信技術硏究論文集 Vol.2 No.-

In this paper, we will compress the data of video signal using motion compensation and wavelet transform method. It is abbreviate to process have not large gain that analysing human visual characteristic for video signal and is compressed to the high portion without low resolution for video signal by abbreviated unsensitive information for human visual. In the result of simulation with 'Football' and 'People', we get high resolution under compress of frame per 30:1.

신경회로망에서 뉴런간의 연결도를 이용한 4백 배치 문제 해결 알고리즘

현해진,김덕주,강부식,이기태,임재윤 濟州大學校 工科大學 産業技術硏究所 1993 産業技術硏究報告 Vol.4 No.-

In this paper we have proposed a method for solving a four-coloring problem using adjusted information transmission between adjacent neurons in neural networks. These algorithms are based on McCclloch-Pitts binary neuron model neural networks. If a map shares n regions, a 4×n neural array is used to color a map of n regions where each neuron as a processing element performs it. By programming these algorithm by a C-language in IBM PC 486 DX and adapting it to various examples, we have showed the ability of our system. If one neuron is selected among four neurons, the strength of order three neurons is wakened. So, by transmitting the information of selected neuron, adjacent neurons cannot share the same color.

저빈도 반복성 경두개 자기자극이 정상인의 시각적 단기 기억에 미치는 영향

오해정,김원,이경욱,박원명,전태연,한진희,채정호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : Repetitive transcranial magnetic stimulation (rTMS) is a novel, noninvasive method of brain stimulation. Since conventional rTMS does not cause seizure, marked advantage over electroconvulsive therapy (ECT), rTMS can be used easily and widely. Once the effects of rTMS on cognitive function are elucidated, its application will be further extended. However, the effects of rTMS on cognitive function have not been well examined. This study aimed to evaluate the effect of low frequencyr TMS on visual short term memory. Methods : Forty normal healthy volunteers were randomly assigned to rTMS (n=20) or sham (n=20) groups. The rTMS group were again randomly divided into left prefrontal (n=10) and right prefrontal (n=10) groups. For each group rTMS was given at 1 Hz for 20 minutes with 100% of motor threshold. As a cognitive task, Corsi Block Tapping Test (CORSI) in the computerized Vienna Test System, which can assess visual short term memory, was performed before, during, and after the rTMS. Results : No significant difference was found in the visual short term memories between the rTMS and the sham groups before, during, or after 1 Hz rTMS, nor between the left and right prefrontal rTMS groups. Conclusion : This study demonstrates that rTMS, contrary to ECT, has no adverse visual short term memory effect when used as the standard treatment paradigm. Therefore, rTMS could be a new and safe treatment method in various neuropsychiathc fields without any interference of cognitive function.