http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
OB-04 : Maternal serum pregnancy-associated plasma protein-A as a predictor of severe preeclampsia
( Ha Yan Kwon ),( Hyo Ryun Lee ),( Ju Hyun Cho ),( Hee Young Cho ),( Young Han Kim ),( Yong Won Park ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-
목적: The aim of study was to evaluate whether a level of maternal serum PAPP-A was associated with preeclampsia and to investigate the role of these screening serum analysis in the prediction of severe preeclampsia. 방법: A retrospective study was conducted in pregnant women presenting for first-trimester aneuploidy screening between January 2009 and December 2013. A total of 33 patients who had developed preeclampsia during the subsequent pregnancy course and 151 woman who had not any adverse obstetric outcomes were identified. Maternal and neonatal data were reviewed from the medical records and PAPP-A, free ß-hCG and NT MoM values were compared between the two groups. 결과: NT and CRL values were no significant difference between two groups(p= 0.501 and p=0.964, respectively). Although free ß-hCG values showed no statistically significant difference(p=0.786), the levels of PAPP-A were significantly decreased in the preeclampsia group compared to the control group(<p=0.05). However, PAPP-A levels were no significant difference between non-severe and severe preeclampsia groups(p=0.268). 결론: Our study showed than low PAPP-A value is associated with preeclampsia, although it is limited as a predictor of preeclampsia severity.
Efficacy of Bakri Balloon Tamponade in Massive Postpartum Hemorrhage: A Series of 57 Cases
( Ha Yan Kwon ),( Young-han Kim ),( Yong-won Park ),( Ja-young Kwon ) 대한주산의학회 2016 大韓周産醫學會雜誌 Vol.27 No.4
Purpose: To evaluate the efficacy of intrauterine Bakri balloon tamponade as a management of massive postpartum hemorrhage (PPH). Methods: Retrospective study including women who underwent intrauterine Bakri balloon tamponade for massive PPH between April 2010 and July 2015 was conducted. Massive PPH was defined as estimated blood loss exceeding 1,500 mL. Bakri balloon was inserted into uterus if women had PPH despite medical treatment after vaginal delivery or cesarean section. The balloon was inflated with sterile saline and removed after 12-24 hours. Failure was defined as needing another procedure for hemorrhage control. Demographic, obstetric and specific factors in regard to the Bakri balloon use were recorded. The successful rate of hemostasis by Bakri balloon was evaluated. Results: Among 138 women with PPH managed Bakri balloon insertion, 57 patients were diagnosed with massive PPH. The most common cause of massive PPH was placenta previa without accreta (54.4%), uterine atony (33.3%), placenta previa with accreta (10.5%) and placenta accreta (1.8%). The mean estimated blood loss was 2279.0 mL (range, 1,500-6,500 mL). The rate of successful control of massive PPH after Bakri balloon placement was 82.5%. From the cases of 57 patients, 10 patients needed additional procedures; five required uterine artery embolization and five underwent cesarean hysterectomy. No short-term complications or maternal death were observed after Bakri balloon insertion. Conclusion: Bakri balloon tamponade is an effective, simple and quick approach in the treatment of massive PPH and it is useful as complementary management for earning time for another procedure.
( Ha Yan Kwon ),( Kyung Mee Choi ),( Hee Young Cho ),( Young Han Kim ),( Yong Won Park ),( Ja Young Kwon ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
To evaluate the risk of cesarean section due cephalopelvic disproportion or induction failure according to maternal pre-pregnant body mass index (BMI), 2009 Institute of Medicine (IOM) gestational weight gain guideline and large for gestational age (LGA) infant. We conducted a retrospective study and analyzed data of 1519 women with singleton full-term birth from 2010 to 2012. Pregnancy with preeclampsia, chronic hypertension, diabetes, gestational diabetes, previous myomectomy status, planned cesearean section due to CPD or elderly primigravida, placenta previa and delivery due to fetal distress or fetal anomaly were excluded. Odds ratio (OR) and 95% confidence intervals of cesarean section were obtained with adjustment for maternal age, parity, gestational age, fetal gender, pre-pregnant BMI, weight gain and birthweight. Of 1519 pregnancies, 178 (11.7%) cases underwent emergency cesarean delivery. Higher pre-pregnant BMI and weight gain tended to have an increased risk of cesarean section, however it was not significant stastically. Pregnancies with LGA infant had a significant association with increasing risk of cesarean section (OR, 2.38 ;95% confidence interval, 1.5-3.5). Women with LGA infant has an increased risk of cesarean section when adjusting for BMI and weight gain. However, maternal pre-pregnant BMI and excess weight gain were not clearly associated with risk of cesarean section in this study.
( Ha Yan Kwon ),( Ja-young Kwon ),( Yong Won Park ),( Young-han Kim ) 대한산부인과학회 2016 Obstetrics & Gynecology Science Vol.59 No.3
Objective To evaluate the risk of emergency cesarean section according to the prepregnancy body mass index (BMI) and gestational weight gain per the 2009 Institute of Medicine guidelines. Methods A retrospective analysis of data from 2,765 women with singleton full-term births (2009 to 2012) who attempted a vaginal delivery was conducted. Pregnancies with preeclampsia, chronic hypertension, diabetes, planned cesarean section, placenta previa, or cesarean section due to fetal anomalies or intrauterine growth restriction were excluded. Odds ratios (ORs) and confidence intervals (CIs) for emergency cesarean section were calculated after adjusting for prepregnancy BMI or gestational weight gain. Results Three-hundred and fifty nine (13.0%) women underwent emergency cesarean section. The adjusted OR for overweight, obese, and extremely obese women indicated a significantly increased risk of cesarean delivery. Gestational weight gain by Institute of Medicine guidelines was not associated with an increased risk of cesarean delivery. However, inadequate and excessive weight gain in obese women was highly associated with an increased risk of emergency cesarean section, compared to these in normal BMI (OR, 5.56; 95% CI, 1.36 to 22.72; OR, 3.63; 95% CI, 1.05 to 12.54; respectively), while there was no significant difference between normal BMI and obese women with adequate weight gain. Conclusion Obese women should be provided special advice before and during pregnancy for controlling weight and careful consideration should be needed at the time of vaginal delivery to avoid emergency cesarean section.
권하얀 ( Ha Yan Kwon ),( Ja-young Kwon ),( Yong Won Park ),( Young-han Kim ) 대한산부인과학회 2017 대한산부인과학회 학술대회 Vol.103 No.-
Objective: To evaluate the risk of emergency cesarean section according to the prepregnancy body mass index (BMI) and gestational weight gain per the 2009 Institute of Medicine guidelines. Methods: A retrospective analysis of data from 2,765 women with singleton full-term births (2009 to 2012) who attempted a vaginal delivery was conducted. Pregnancies with preeclampsia, chronic hypertension, diabetes, planned cesarean section, placenta previa, or cesarean section due to fetal anomalies or intrauterine growth restriction were excluded. Odds ratios (ORs) and confidence intervals (CIs) for emergency cesarean section were calculated after adjusting for prepregnancy BMI or gestational weight gain. Results: Three-hundred and fifty nine (13.0%) women underwent emergency cesarean section. The adjusted OR for overweight, obese, and extremely obese women indicated a significantly increased risk of cesarean delivery. Gestational weight gain by Institute of Medicine guidelines was not associated with an increased risk of cesarean delivery. However, inadequate and excessive weight gain in obese women was highly associated with an increased risk of emergency cesarean section, compared to these in normal BMI (OR, 5.56; 95% CI, 1.36 to 22.72; OR, 3.63; 95% CI, 1.05 to 12.54; respectively), while there was no significant difference between normal BMI and obese women with adequate weight gain. Conclusion: Obese women should be provided special advice before and during pregnancy for controlling weight and careful consideration should be needed at the time of vaginal delivery to avoid emergency cesarean section.
유방암이 진단된 젊은 한국 여성에서 발견한 크루켄버그종양
권하얀 ( Ha Yan Kwon ),남은지 ( Eun Ji Nam ),김상운 ( Sang Wun Kim ),김영태 ( Young Tae Kim ) 대한산부인과학회 2011 Obstetrics & Gynecology Science Vol.54 No.10
Metastasis of breast cancer to lung, bone and liver is common, but metastasis to ovaries is rare in Korea. A 31-year-old woman diagnosed with breast cancer was referred to our department due to a newly detected adnexal mass via abdomen sonography during regular check-up. Imaging studies revealed solid mass on left ovary and enlarged lymph nodes. She underwent a laparotomy including hysterectomy, bilateral salpingo-oophorectomy, lymphadenectomy, with a suspected impression of primary ovarian neoplasms or Krukenberg tumors. Pathologic findings revealed metastatic adenocarcinoma from breast cancer involving left ovary and paraaortic lymph nodes. To our knowledge, this is the youngest Korean patient with Krukenberg tumors from the breast. In Korea, since the average age affected by breast cancer is younger than in the West, and the incidence and the mortality of breast cancer has increased, possible ovarian metastasis should be kept in mind when Korean patient with breast cancer visits for follow-up.
Yan, Bing Chun,Park, Joon Ha,Kim, Sung Koo,Choi, Jung Hoon,Lee, Choong Hyun,Yoo, Ki-Yeon,Kwon, Young-Geun,Kim, Young-Myeong,Kim, Jong-Dai,Won, Moo-Ho Kluwer Academic/Plenum Publishers 2012 Cellular and molecular neurobiology Vol.32 No.8
<P>In the present study, we investigated neuronal death/damage in the gerbil hippocampal CA1 region (CA1) and compared changes in some trophic factors, such as brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF) and vascular endothelial growth factor (VEGF), in the CA1 between the adult and young gerbils after 5 min of transient cerebral ischemia. Most of pyramidal neurons (89%) were damaged 4 days after ischemia-reperfusion (I-R) in the adult; however, in the young, about 59% of pyramidal neurons were damaged 7 days after I-R. The immunoreactivity and levels of BDNF and VEGF, not GDNF, in the CA1 of the normal young were lower than those in the normal adult. Four days after I-R in the adult group, the immunoreactivity and levels of BDNF and VEGF were distinctively decreased, and the immunoreactivity and level of GDNF were increased. However, in the young group, all of their immunoreactivities and levels were much higher than those in the normal young group. From 7 days after I-R, all the immunoreactivities and levels were apparently decreased compared to those of the normal adult and young. In brief, we confirmed our recent finding: more delayed and less neuronal death occurred in the young following I-R, and we newly found that the immunoreactivities of trophic factors, such as BDNF, GDNF, and VEGF, in the stratum pyramidale of the CA1 in the young gerbil were much higher than those in the adult gerbil 4 days after transient cerebral ischemia.</P>