석탄 가스화를 통한 전력 생산과 DME 병산 공정에 대한 기초 경제성 분석

유영돈 ( Young Don Yoo ),김수현 ( Su Hyun Kim ),조원준 ( Won Jun Cho ),모용기 ( Yong Gi Mo ),송용택 ( Tae Kyong Song ) 한국화학공학회 2014 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.52 No.6

석탄가스화를 기반으로 한 발전(IGCC 발전) 및 화학원료 제조공정의 상업화 관건은 화석연료인 원유 또는 천연가스를 기반으로 생산되는 경우와 비교하여 경제성을 확보할 수 있는지 여부이다. 경제성 확보를 위한 가장 현실적인 방법으로는 석탄 가스화를 통해 얻어진 합성가스로부터 2개 이상의 생산물(예: 발전과 화학원료를 동시 생산)을 병산(coproduction또는 poly-generation)하는 것이다. 본 연구에서는 석탄 가스화를 기반으로 하여 발전과 수송용, 발전용 및 가정용 연료로 사용이 가능한 DME(dimethyl ether)를 병산하는 공정에 대한 경제성 분석을 실시하였다. 경제성 분석을 위한 병산 공정에서는 250 MW 전력생산 연간 30만 톤의 DMZ 생산을 기준으로 하였다. 병산 공정에서 DME 판매가격이 50만원/ton인 경우, 전기 생산원가는 34.8~58.4원/kWh으로 SMP(계통한계가격) 가중평균인 150.69원/kwh(2013년 1월~12월까지의 평균값)의 33~58% 수준으로 산정되었다. 따라서, DME 판매가격이 적정하게 유지될 경우 석탄IGCC+DME 병산공정은 IGCC 단독 발전과 비교하여 경제성을 확보할 수 있을 것으로 판단된다. 현재 중국에서 DME판매가격이 900,000원/톤 내외이므로, 전력과 DME를 병산할 경우, IGCC 단독으로 전력을 생산할 경우와 비교하여 전력 생산 원가를 월등하게 낮출 수 있음을 알 수 있다. 이와 같이 석탄 가스화를 기반으로 한 병산 공정을 통해 전력과 DME를 병산하는 시스템에서, 시장 여건에 따라 전력과 DME 생산비율 제어가 가능하고, 석탄 가스화기 및 정제 시스템을 공통 설비로 활용함으로써, 개별적으로 생산하는 것보다 생산 원가를 낮출 수 있다는 결과를 얻었다. The key for the commercial deployment of IGCC power plants or chemical (methanol, dimethyl ether, etc.) production plants based on coal gasification is their economic advantage over plants producing electricity or chemicals from crude oil or natural gas. The better economy of coal gasification based plants can be obtained by co-production of electricity and chemicals. In this study, we carried out the economic feasibility analysis on the process of co-producing electricity and DME (dimethyl ether) using coal gasification. The plant’s capacity was 250 MW electric and DME production of 300,000 ton per year. Assuming that the sales price of DME is 500,000 won/ton, the production cost of electricity is in the range of 33~58% of 150.69 won/kwh which is the average of SMP (system marginal price) in 2013, Korea. At present, the sales price of DME in China is approximately 900,000 won/ton. Therefore, there are more potential for lowering the price of co-produced electricity when comparing that from IGCC only. Since the co-production system can not only use the coal gasifier and the gas purification process as a common facility but also can control production rates of electricity and DME depending on the market demand, the production cost of electricity and DME can be significantly reduced compared to the process of producing electricity or DME separately.

Genetic Diversity and Pathogenicity of Cylindrocarpon destructans Isolates Obtained from Korean Panax ginseng

Song, Jeong Young,Seo, Mun Won,Kim, Sun Ick,Nam, Myeong Hyeon,Lim, Hyoun Sub,Kim, Hong Gi The Korean Society of Mycology 2014 Mycobiology Vol.42 No.2

We analyzed the genetic diversity of Cylindrocarpon destructans isolates obtained from Korean ginseng (i.e., Panax ginseng) roots by performing virulence tests and nuclear ribosomal gene internal transcribed spacer (ITS) and mitochondrial small subunit (mt SSU) rDNA sequence analysis. The phylogenetic relationship analysis performed using ITS DNA sequences and isolates from other hosts helped confirm that all the Korean C. destructans isolates belonged to Nectria/Neonectria radicicola complex. The results of in vivo and ex vivo virulence tests showed that the C. destructans isolates could be divided into two groups according to their distinctive difference in virulence and the genetic diversity. The highly virulent Korean isolates in pathogenicity group II (PG II), together with foreign isolates from P. ginseng and P. quinquefolius, formed a single group. The weakly virulent isolates in pathogenicity group I, together with the foreign isolates from other host plants, formed another group and exhibited a greater genetic diversity than the isolates of PG II, as confirmed by the mt SSU rDNA sequence analysis. In addition, as the weakly virulent Korean isolates were genetically very similar to the foreign isolates from other hosts, they were likely to originate from hosts other than the ginseng plants.

Arachidonic Acid 12-lipoxygenase (ALOX12) Promotes Pulmonary Fibrosis

( Gi Won Hwang ),( Sang Eun Lee ),( Su Jin Moon ),( Jin Woo Song ) 대한결핵 및 호흡기학회 2021 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.129 No.-

Background 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) is product of arachidonic acid metabolism through the enzyme of arachidonic acid 12-lipoxygenase (ALOX12) in human platelets or leukocytes. ALOX12 plays an important role in inflammation and oxidation and is involved in development of various human diseases. However, the role of 12(S)-HETE and ALOX12 in the pathogenesis of idiopathic pulmonary fibrosis (IPF) remains unexplored. We investigated the role of ALOX12 in IPF. Methods The level of 12-HETE was measured in human plasma (healthy control = 40, IPF = 76) via liquid chromatography-mass spectrometry (LC-MS/MS). The function of 12-HETE and ALOX12 were evaluated in TGF-β1-stimulated human lung fibroblast (MRC-5 cell, primary lung fibroblast) using ALOX12 inhibitor or silencing RNA (siRNA). The anti-fibrotic effects of ALOX12 inhibitor were evaluated in bleomycin-induced mice model of pulmonary fibrosis. Results The level of 12-HETE was significantly increased in plasma of IPF patients compared with controls. 12-HETE increased protein expression levels of collagen I and fibronectin in human lung fibroblast. ALOX12 levels were increased in lung tissues of patients with IPF and human lung fibroblasts stimulated by TGF-β1 compared with those of controls. ALOX12 inhibitor and ALOX12 specific siRNA downregulated protein expression levels of collagen I and fibronectin increased by TGF-β1 in human lung fibroblasts. In addition, ALOX12 inhibitor decreased TGF- β1 induced phosphorylation of Smad2/3 in MRC-5 cell. In bleomycin treated mice, ALOX12 inhibitor decreased levels of hydroxyproline in the lung compared of control mice. Conclusions Our findings suggest that inhibition of ALOX12 may have anti-fibrotic effects on pulmonary fibrosis, suggesting that ALOX12 is implicated as a potential therapeutic target in IPF.

Donor Biliary Complications in High-Volume Living-Donor Liver Transplantation Center in Korea

( Gi-won Song ),( Gil-chun Park ),( Dong-hwan Jung ),( Tae-yong Ha ),( Ki-hun Kim ),( Shin Hwang ),( Sung-gyu Lee ),( Eun-kyung Jwa ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Donor safety is the most important Living donor liver transplantation. Biliary complication is common complications in donor hepatectomy. This study intended to analyze the incidence and outcomes of donor biliary complications in a Korean high-volume LT center. Methods: Institutional LT database was searched from 2006.01.01 to 2011.05.31. Their medical records and imaging studies were reviewed. All of them did AMC technique for BD division. Results: Between 2006.01.01-2011.5.31, total 1658 donors did hepatectomy in AMC center. Among them, 1099 were male and 559 were female. Graft types were Right liver graft in 1302 (78.5%), Left liver graft in 274 (16.5%), Left lateral section graft in 72 (4.3%) and Right posterior section graft in 10 (0.6%). Mean age of total donor was 29 years and Mean steatosis of liver was 5.7%. Mean hospital days was 12days and Mean follow-up period were 17.5 month. Among 1658 donors, the biliary complications occurred in 47 donors (2.7%). Most of them were bile leak, only 2 case were bile duct stenosis. All of the biliary complication occurred in early period (< 1 month). In the biliary complication(BC) group, the 10 donors did percutaneous drainage(21.3%) and the 12 donors did ERCP(25.5%) and the only one donor was re-operated. Mean hospital days in BC group was 22 days and mean duration of treatment was 1.8 month. Hospital days in BC group was more longer than non- BC group but, there is no significant difference. Conclusions: Very low incidence of BC in donor by using AMC technique for BD division. The incidence of late BC in LD hepatectomy is neglisible.

Effect of Circuit Training on Aging-related Hormones in Obese Middle-aged Women

Won-Mok Son(손원목),Yi-Sub Kwak(곽이섭),Gun-Do Kim(김군도),Min-Sung Ha(하민성),Song-Young Park(박송영),Gi-Dong Sung(성기동) 한국생명과학회 2017 생명과학회지 Vol.27 No.9

노화 과정에 따라 중년 여성들은 폐경 이후 체력이 저하되기 시작하면서 체지방 증가와 제지방량의 감소로 비만으로 이어지기 쉽고, 이러한 현상은 체내 호르몬의 분비의 변화와 함께 발생된다. 본 연구는 서킷 트레이닝이 비만 중년 여성의 노화 관련 호르몬에 미치는 영향을 구명하기 위해 실시하였다. 대상자 체지방률 30% 이상인 비만 중년 여성 운동군 10명, 대조군 10명 총 20명을 실시하였다. 운동 시간은 준비운동 5분, 본 운동 20분, 정리운동 5분으로 총 30분 주 3회 실시하였으며, 운동 강도는 운동자각도를 이용하여 13~17(약간 힘들다-매우 힘들다)수준으로 실시하였고, 또한 POLAR 심박수 변화량을 측정하여 1~6주는 60~70%HRR (Heart rate reserve), 7~12주는 70~80%HRR로 설정하였다. IGF-1은 운동군이 유의하게 증가하였으며, GH는 운동군이 유의하게 증가하였고, DHEA-S는 운동군이 유의하게 증가하였다. 이상의 결과 서킷 트레이닝이 비만 중년 여성의 노화 관련 호르몬에 긍정적인 영향을 준 것으로 사료된다. Due to aging, the physical fitness of middle-aged women decreases after menopause. This results in increased body fat and reduced lean body mass, both of which can lead to obesity. This phenomenon is accompanied by changes in hormone secretion in the body. The purpose of this study was to analyze the effects of circuit training on aging-related hormones in obese middle-aged women. The subjects were 20 obese middle-aged women. The subjects were divided into two groups: a circuit training group (n=10) and nonexercise control group (n=10). Growth hormone (GH), insulin-like growth factor-1 (IGF-1), estrogen, and DHEA-S were measured before and after the circuit training program. The circuit training group performed circuit training for 12 weeks, three times per week. Exercise intensity was increased gradually from 60% to 80% of heart rate reserve every 6 weeks. In the circuit training group, at the end of the 12-week training program, the IGF-1 levels were significantly increased compared to pre-exercise levels, and they were higher than those of the control group. GH levels were also significantly increased in the circuit training group, but the differences were not statistically significant. DHEA-S was significantly increased in the circuit training group, but the difference was not statistically significant. The results showed that circuit training improved aging-related hormones levels in obese middle-aged women.

Salvage living donor liver transplantation versus repeat liver resection for patients with recurrent hepatocellular carcinoma and liver cirrhosis: A propensity score-matched comparison

Gi-Won SONG,Young-In YOON 한국간담췌외과학회 2021 Annals of hepato-biliary-pancreatic surgery Vol.25 No.-

Content based Similar Image Retrieval Method using Deep Neural Network

Gi-won Lee,Ju-Hyeong Maeng,Seok-il Song 한국콘텐츠학회 2021 한국콘텐츠학회 ICCC 논문집 Vol.2021 No.12

Surgical challenges beyond conventional hepatectomy

Gi-Won Song 한국간담췌외과학회 2013 한국간담췌외과학회 학술대회지 Vol.2013 No.4

Clinicopathological features of the intraductal papillary neoplasms of the intrahepatic bile duct

Gi-Woong Jang,Shin Hwang,Yong-Joo Lee,Ki-Hun Kim,Kwang-Min Park,Chul-Soo Ahn,Deok-Bog Moon,Tae-Yong Ha,Gi-Won Song,Dong-Hwan Jung,Gil-Chun Park,Sung-Gyu Lee 한국간담췌외과학회 2012 한국간담췌외과학회지 Vol.16 No.4

Backgrounds/Aims: This study is intended to investigate the clinicopathological features of the intraductal papillary neoplasms of the intrahepatic bile duct (IPNB), especially focused on malignant changes. Methods: From the institutional database of liver resection cases (Asan Medical Center, University of Ulsan College of Medicine), 18 patients who met the definition of IPNB were selected. They had undergone liver resection between February 2002 and October 2006; thus, the follow-up period was more than 5 years. Results: Of the 18 patients, 11 patients were male. Their mean age was 61.3±6.7 years. There were no differences between the non-malignant and malignant lesions, in the comparison of the CEA levels (5.6±2.7 vs.12.6±31.1 ng/ml, p=0.439) and the CA19-9 levels (29.2±34.7 vs.31.9±30.2 ng/ml, p=0.871). The common radiologic findings were: intraductal growing mass in 10; bile duct dilatation in 6; and saccular duct dilatation in 2. Left and right hepatectomies were performed in 15 and 3, respectively. Five patients showed benign lesions of IPNB, and 13 patients revealed malignant lesions of intraductal papillary adnocarcinoma or cholangiocarcinoma. All 4 patients with benign lesions survived for a mean period of 53 months without recurrence. In 13 patients with the malignant lesions, 1-year, 3-year, and 5-year survival rates were 100%, 84.6%, and 59.2%, respectively. Conclusions: We concluded that intrahepatic IPNB is a rare type of biliary neoplasm which includes a histological spectrum, ranging from benign disease to invasive malignancy. The long-term survival was anticipated after complete curative resection. (Korean J Hepatobiliary Pancreat Surg 2012;16:138-141)

Distributed Monitoring and Control on LonWorks/IP Virtual Device Network

Song, Ki-Won,Kim, Jong-Hwi,Choi, Gi Sang 서울시립대학교정보기술연구소 2002 정보기술연구소 논문집 Vol.4 No.-

Requirements for Distributed Monitoring and Control Networks (DMCN) differ greatly from those of typical data networks. Specifically, any DMCN technology which employs a fieldbus protocol is different from IP network protocol TCP/IP. In general, one needs to integrate fieldbus protocol and TCP/IP to realize DMCN over IP network or internet, which can be viewed as Virtual Device Network (VDN). Interoperability between devices and equipments is essential to enhance the quality and the performance of predictive maintenance (PM). This paper suggests a basic framework for VDN using DMCN over IP network and a method to guarantee interoperability between devices and equipments.