양 하지의 근력저하를 주소로 응급실로 내원한 원발성 알도스테로증 1예

안력,김원,조규종,홍정석,이미우,장성은,오세현,임경수 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

A primary central nervous system lymphoma(PCNSL) is defined as a lymphoma limited to the cranial-spinal axis without systemic involvement. PCNSLs were formerly very rare, only 0.5∼ 1.2% of all intracranial neoplasms, and were usually associated with acquired immuno-deficiency syndrome(AIDS) and other immune-compromised states. Recently, there has been a clear rise in the incidence of this disease among normal individuals. We describe a 77-year-old female with hyponatremia who presented with a confused mental state. Computed tomography(CT) of the brain demonstrated a suprasellar mass with enhancement. We evaluated the basic hormonal studies and the magnetic resonance imaging(MRI). A ventricular biopsy was done, and the result was a diffuse, large, B-cell-type malignant lymphoma. She presented panhypopituitarism and partial central diabetes insipidus. She received chemotheraphy and was discharged in an improved condition. We report a case of panhypopituitarism due to PCNSL and give a review of the literature.

연골외막세포가 포함된 alginate beads를 이용한 토끼에서의 골연골결손 치료

안현정,김은미,정미현,조현철,이인범,성상철,이명철 대한정형외과연구학회 2003 대한정형외과연구학회지 Vol.6 No.2

입원 환자 영양검색 전산 프로그램 개발

안수미,윤기영,신연명,최경현,임근승,장문경,송윤미,공은희 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

Background : About 30% of patients in the hospital are under nourishment. A large portion of people are undernourished when they are admitted to the hospital and in the majority of these, undernutrition develops further while in hospital. Patient-Generated subjective global assessment(PG-SGA), a method of nutritional assessment based on clinical judgment, has been widely used to assess the nutritional status of adults for both clinical and research purposes. Modified PG-SGA can be used as a nutrition screening tool, and a comprehensive nutrition assessment is desirable for those who are malnourished. The purpose of this study is to develop a simple, reliable and valid nutrition screening program(NSP). Methods : We applied the nutrition screening program(NSP) to adult inpatients who are at risk of malnutrition using the Modified Patient-Generated subjective global assessment(PG-SGA) and objective assessment(electrical medical record data). Results : Therefore simple and beneficial NSP is developed for patients with severe malnutrition. Using NSP. nutritional information of the severe malnutrition patient should be shared with the physicians and they should be taken care of by clinical dietitians to improve their nutritional status. Conclusion : The Modified PG-SGA and nutrition screening tool are simple, reliable and valid nutrition screening program(NSP).

지형적 방법을 이용한 인물영상의 윤곽선 추출

안은영,송미영 남서울대학교 1998 남서울대학교 논문집 Vol.4 No.-

In this paper, we suggest a new method to contour extraction from the given gray-scale character image using topological method. Many proposed methods are not fitable to extract contour of character image because character features (like ridge of nose, chin etc.) are not extracted by the methods. We use topological method from gray scale character image directly and minimize the character inforamtion of the input image and extrat contour of character feature.

소양호에서 세균군집 크기에 미치는 폴랑크톤의 영향

안태석,정미정,이은주,조규송 江原大學校 附設 環境硏究所 1996 環境硏究 Vol.13 No.-

To scrutinize the biological effects of plankton communities to bacterial community, the total bacterial numbers, chlorophyll a concentration and phytoplankton, zooplankton communities were analyzed in Lake Soyang from May 13, to July 14, 1994. At 0m depth, total bacterial numbers positively coi-related with chlorophyll o concentration. On the other hand, at 2m depth, the two parameters had negative correlation. At the middle of the June, whe dominants of phytoplankton, zooplankton were changing, the bacterial numbers dropped down. These results suggest that as the Anabaena becoming dominant species, the some zooplankton species changed to bacterivore. The bacterial community was mainly effected by phytoplankton at 0m, and by zooplankton at 2m depth.

다매체를 이용한 단계적 창작무용 학습이 아동의 창의성 발달에 미치는 영향

김미자,안은주 서울교육대학교 2003 한국초등교육 Vol.14 No.2

말단 비대증의 임상적 특성

박은미,안용환,김현정,김병수,임종주,김하영,박병현,조정구 圓光大學校 醫科學硏究所 2004 圓光醫科學 Vol.19 No.2

한국인에서 NOTCH4 유전자 내 두 개의 단일염기다형성과 정신분열병의 연합연구

주은정,정성훈,김미재,구영진,배승오,안용민,이규영,김용식 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : Previous studies on N0TCH4 gene and schizophrenia have not produced consistent results, and more studies with various ethnicities and populations were warranted. This study was performed with Korean population to find the role of the N0TCH4 gene in the development of schizophrenia. Methods : 235 schizophrenics and 236 normal controls participated in the study. Two SNPs (-1725 A/G and -25 T/C) on the N0TCH4 gene were investigated. Genotyping was done by Taqman assay, and statistical analysis was done by contingency chi-square test for the allele and genotype frequencies and PowerMarker V3.0 for the haplotype. Results : The two SNPs did not deviate from Hardy-Weinberg equilibrium in neither schizophrenics or normal controls. Two groups were not different in terms of allele and genotype distribution for both SNPs. Two SNPs were found to be in linkage disequilibrium. Haplotype analysis could not find an association between schizophrenia and these two SNPs. There was no association between the age at onset and the genotypes for both SNPs. Conclusion : We could not find any significant association between schizophrenia and the N0TCH4 gene in this Korean population. Although there are limitations in this study, this result supports the conclusion that the N0TCH4 gene is less likely to play a major role on the development of schizophrenia in the Asian population.

정상인에서 전기 및 자기 자극을 이용한 설 근육의 전기생리학적 평가

조은미,류종현,안성환,조경원,임건한,김진호,김후원 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.1

Background: Abnormality of lingual muscles is clinically common. But its exact clinical assessment is quite difficult. Evaluation of motor power of the lingual muscles and their neural pathway is limited because of anatomical inaccessibility and individual variation of subjective symptoms. Transcranial magnetic stimulation (TMS) of the human motor cortex is a non-invasive tool to assess the functional integrity of the fast conducting central motor pathways and electrical stimulation of lingual nerve is a conventional method of peripheral nerve conduction. Therefore both study will be helpful to understanding of pathophysiology of lingual abnormality. Until now there is no such report in Korea. This study was conducted to acquire the easier method and normal control values of Korean subjects. Method: We recorded the motor responses from the lingual muscles of 32 healthy subjects (22 men, 10 women) by focal cortical TMS with a circular coil. Motor potentials were recorded by means of surface electrodes applied on the both side of the tongue, following TMS several centimeters lateral from the vertex and parietooccipital cortex and peripheral electrical stimulation of the 12th cranial nerve at the lateral 1/3 point of the line between the midline and angle of mandible. Results: During moderate motor activation, majority of maximal motor response were obtained 4-6cm lateral to the vertex with similar latencies. And the responses from magnetic stimulation of the intracranial segment of hypoglossal nerve were discarded because of difficulty to obtain and unsatisfactory reproducibility. The latency of motor evoked potentials in right cortical stimulation was 10.08 ± 1.17 msec and in left stimulation 10.04 ± 1.32 msec. The amplitudes in right 2.15 ± 1.02, left 2.09 ± 1.11 mV. The latencies electric hypoglossal nerve stimulation were 2.42 ± 0.34 in right, 2.49 ± 0.35 msec in left side. The amplitudes were 2.90 ± 2.37 in right, 2.43 ± 1.86 mV in left side. Central conduction times as calculated by subtracting the response latencies obtained by magnetic and electric stimulation are right 7.65 ± 1.19, left 7.55 ± 1.35 msec. There was no significant difference between man and woman, Conclusion: The method may be efficient, noninvasive, painless, and easy reproduced. With more extensive application to various neurological disorders, it comes close to being an ideal clinical conduction study technique for this cranial nerve.

ADHD 아동을 위한 예술치료 프로그램 개발 : 영상매체 활용을 중심으로

이에스더,안은미 한국문화교육학회 2012 문화예술교육연구 Vol.7 No.1

고도화된 물질문명의 시대가 가속화됨에 따라 현대인들에게 인간소외 현상, 정신적 불안과 공포, 자아감 상실 등의 역기능 현상들이 나타나고 있다. 이 뿐만 아니라 일반아동에게서도 일시적인 정신장애나 행동상의 문제가 나타나고 있다. 특히 학교, 가정 그리고 또래집단의 관계형성에서 여러 가지 행동장애를 일으키는 ADHD 아동이 늘어나고 있다. ADHD 아동은 기질적으로나 환경적으로 심리가 불안하고 정서가 안정되지 못하는 특징을 지니고 있다. 이러한 아동들이 좋아하고 관심을 가지는 영상매체를 활용하여 예술치료 프로그램을 적용한다면 그들의 문제점들을 보다 더 명확하게 파악하여 이를 개선할 수 있다고 본다. 이에 본 연구는 ADHD 아동의 인지·정서·행동개선을 위해 영상매체 활용 음악, 미술, 동작, 놀이가 통합될 수 있는 예술치료 프로그램을 개발하였다. 1회기부터 8회기까지 총 8개의 프로그램으로 설계하였고, 치료단계는 초기, 중기, 종결로 구성하였다. 처음 1회기와 2회기는 초기단계로 치료사와 집단 간의 적응 및 탐색을 통해 라포 형성에 목표를 두었고, 3회기부터 6회기는 중기단계로 주의집중과 정서조절능력을 키워줄 수 있도록 하였다. 마지막 7회기부터 8회기는 종결단계로 긍정적인 피드백을 주고받는 과정에서 집중력을 높이고 그들의 행동에 긍정적 변화를 도출할 수 있도록 구성하였다. Acceleration of a highly developed material civilization has caused adverse effects such as the human alienation phenomenon, mental anxiety and fear, loss of self-esteem, etc. Furthermore, normal children are also suffering from temporary mental disabilities or behavioral disorders. More children with ADHD are having behavioral problems at their school, at home and when they form peer relationships. Children with ADHD have characteristics of being temperamentally and environmentally unstable. Application of programs that utilize visual media and arts therapy that draw these children's interests can help finding solutions by figuring out their problems more clearly. Therefore, this study developed an integrated arts therapy program of music, art, motion and game utilizing visual media for the cognitive, psychological and behavioral improvement of children with ADHD. The program consists of eight programs that are divided into beginning, middle and ending sessions. The first and the second sessions are the beginning stages that aimed for establishing a close rapport between the clients and the therapists by adaptation and exploration, and from the third to the sixth sessions are the middle stages that focused on enhancing their span of attention and emotional concentration ability. The seventh and the eight sessions are the final stages that focused on improving the clients' concentration ability and fostering positive changes of their behaviors by exchanging positive feedbacks.