다발성 골수종

최은숙,고광준 大韓口腔顎顔面 放射線學會 1993 Imaging Science in Dentistry Vol.23 No.2

This is a report of multiple myeloma occurred in the left mandibular body and skull. 66-year-old patient was referred to our hospital with a complaint of painful swelling on the left mandibular body area. The author diagnosed it as a multiple myeloma by the clinical examination, radiographic findings, laboratory findings and the histopathological findings. The purpose of this report is to aid in the diagnosis of multiple myeloma and to aid to differentiate it from malignant tumours. The characteristic features are as follows: 1. In clinical examination, painful swelling was observed in left mandibular body area. 2. In radiographic findings, radiograms showed relatively ill-defined radiolucency without sclerotic border in left mandibular body area. And also represented multiple punched-out radiolucency in the skull and pathologic fracture of vertebral body on lumbar 3 level. 3. In histopathologic findings, infiltration of abnormal plasma cells was observed. 4. In laboratory findings, decreasing of albumin/globulin ratio, hypercalcemia, renal impairment was observed, but we could not find the Bence-Jones protein in urin.

상악골에 발생된 연골형성형 측피질골육종

최선영,고광준,최은숙 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.2

39-year-old female had been treated for the exophytic mass on buccal aspect of the left maxillary posterior area 2 years and 8 months ago. Tentative diagnosis was obtained as fibrous dysplasia on clinical and radiographic examinations and histopathologic findings revealed as osteochondroma after bone trimming at that time. She revisited for the treatment of recurred lesions. We reviewed this case with clinical, radiologic and histopathologic standpoints retrospectively, and came to a conclusion that the tumor primarily occurred was juxtacortical osteogenic sarcoma and recurred due to inadequate treatment and then expanded over intramedullary. This case shows that the diagnosis of osteosarcoma should take account of the patient history, clinical, radiographic and histopathologic findings and it requires attentive follow up check. Retrospectively reviewed results were as follows ; At first visit, oral examination revealed a bony hard swelling on the buccal aspect of the left maxillary posterior area. Radiographically, a dense radiopaque mass was noted on the site. The lesion showed hot uptake of? Tc-MDP. Histopathologic diagnosis was done as osteochondroma, but it was considered as osteogenic sarcoma when compared with the recurrent lesion. When she revisited for the treatment of multiple bony swelling on the left maxilla, radiograms showed typical features of malignancy such as widening of periodontal ligament space and sunray appearace, and coincided with benign characters as follows ; relatively well circumscribed lesion and expansion and displacement of the adjacent structures. Finally, histopathologic findings of the lesion was well differentiated chondroblastic osteogenic sarcoma.

양로원 노인에서 인지기능 평가에 대한 연구

최성환,정은기,김유광 大韓神經精神醫學會 1993 신경정신의학 Vol.32 No.6

The aged population is growing rapidly in Korea. In 1989, the people aged 65 and older marked 4.7% of the population and is expected to exceed 5% in 1993. It has been considered that as the elderly grow older, their cognitive function decline. As the proportion they take in the society is becoming larger, the use of more stable and reliable examination tools become more important to deal with and prevent their cognitive dysfunction. This study looked into the characteristics of cognitive functions of the elderly living in nursing homes. Mini-mental status examination and Brief cognitive rating scale were administered to 530 eldery(mean age 76±7.5) residing in 8 nursing homes located in Kyun-Gi province, vicinity of Seoul, in 1989 and in 1991. Cognitive function correlated with educational level, but not with age. The correlation of MMSE with BCRS was high. According to the results, it was not evident that aging deteriorates cognitive function. The deterioration of cognitive function was related to educational level. MMSE and BCRS were considered appropriate instruments in brief assessment of cognitive function and its prognosis in the elderly. Lengthened follow up interval and the cognitive evaluation of more various groups are desired in the future studies.

안면골 외상환자의 전산화단층상을 이용한 삼차원재구성상의 비교 연구

최은숙,고광준 大韓口腔顎顔面 放射線學會 1994 Imaging Science in Dentistry Vol.24 No.2

The purpose of this study was to clarify the spatial relationship in presurgical examination and to aid surgical planning and postoperative evaluation of patients with facial bone injury. For this study, three-dimensional images of facial bone fracture were reconstructed by computed image analysis system and three-dimensional reconstructive program integrated in computed tomography. The obtained results were as follows: 1. Serial conventional computed tomograms were value in accurately depicting the facial bone injuries and three-dimensional reconstructive images demonstrated an overall look. 2. The degree of deterioration of spatial resolution was proportional to the thickness of the slice. 3. Facial bone fractures were the most distinctly demonstrated on inferoanterior views of three-dimensional reconstructive images. 4. Although three-dimensional reconstructive images made diagnosis of fracture lines, it was difficult to identify maxillary fractures. 5. The diagnosis of zygomatic fractures could be made equally well with computed image analysis system and three-dimensional reconstructive program integrated in computed tomography. 6. The diagnosis of mandibular fractures could be made equally well with computed image analysis system and three-dimensional reconstructive program integrated in computed tomography.

퍼지 논리 제어기를 이용한 유도 전동기 전류 제어에 대한 연구

崔洪圭,全光鎬,姜泰垠 홍익대학교 산업기술연구소 1995 産業技術 Vol.5 No.-

In this paper, we propose the control method of an inverter-fed induction motor using Fuzzy Logic Controller. The FLC chooses the switching states based on a set of fuzzy variables. Error in flux component magnitude of stator current error in torque component magnitude of stator current and flux position are used as fuzzy state variables. Fuzzy rules are determined by observing the vector diagram of flux and currents. The proposed controller shows a good dynamic speed response and decoupling characteristics. Moreover, since the rotor parameter has no effects on the performance the controller and the fuzzy controller possesses highly adaptive capability the performance of fuzzy controller is quite robust and insensitive to the motor parameters and change of operation conditions

유도 전동기의 동특성 개선을 위한 퍼지 제어기 설계

최홍규,전광호,최병숙,강태은 홍익대학교 산업기술연구소 1998 産業技術 Vol.8 No.-

The conventional PI control that are used in the control loop for outer speed of the induction motor, also has difficulty dealing with the dynamic speed tracking parameter variation and the load disturbance. As a result, the motion control system operates with a poor performance in the motor's low speed range. In this dissertation a novel speed control system that implements and fuzzy logic controller(FLC) is proposed. The proposed FLC used the speed error its rate of change and the drive current as three fuzzy variables. The real command output current is chosen by the dufuzzification of the fuzzy output extracted from the fuzzy control rules. The flux and the torque of the induction motor are estimated using the dynamic model with an excellent dynamic response over a wide speed range and with the rotor flux field-oriented scheme of the decoupling characteristics. The performance of this control system is substantiated by computer simulations.

누에 배자와 난소의 초대 배양에 있어서 세포의 분화형태

최광호,손홍대,조은숙 東亞大學校生命資源科學大學附設 農業資源硏究所 1997 農業生命資援硏究 Vol.6 No.1

곤충 세포의 초대 배양에 있어서 그 분화양상을 관찰하기 위하여 누에 배자와 난소를 초대 배양하였다. 그 결과 몇 가지 상이한 세포형이 관찰되었는데 배자 초대 배양의 분화형태는 상피형 세포와 망상조직을 형성하는 섬유상 세포가 관찰되었고, 난소에서는 주로 상피형 세포가 관찰되었다. 또한 두 조직 모두에서 거대 세포보다는 작지만 다소 큰 세포 형태가 관찰되었다. This study was carried out to investigation for differential charaterization of the cells in primary culture with insects. In the process of primary culture with embryos and larval ovaries of silkworm, Bombyx mori, three types of cells were observed. Fibroblast-like cells which formed network and epitherial-like cells migrated from embryos. But in case of ovaries, fibroblast-like cells were not found. Somewhat large cells but smaller than giant-cells were observed in the cultured embryos and ovaries.

디밍 안정기를 이용한 형광등의 퍼지 제어기 설계

崔洪圭,全光鎬,姜太垠,崔琁雄 홍익대학교 산업기술연구소 1997 産業技術 Vol.7 No.-

This paper proposes Dimming Ballast illumination control method using fuzzy reasoning the proposed method has the following effects. First the power saving above 50% is accompanied by the automatic control of the illumination and the choice of a turn-on or -off of a fluorescent lamps that is accompanied by the number of person and working time and weather Second the maintainment of the best illumination in spite of time and weather variation. Third More simple establishment and low than BAS(Building Automation System) because need not main control unit or communication cable

시험관내 KB세포주의 방사선 및 항암제감수성에 관한 연구

고광준,최은숙,홍성우 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.1

The purpose of this study was to aid in the prediction of tumor cell tolerance to radiotherapy and/or chemotherapy. For this study, cell surviving curves were obtained for human squamous cell carcinoma KB cell line after radiation exposure and/or administration of antitumor drugs. 2, 4, 6, 8, 10Gy were irradiated at a dose rate of 210cGy/min using ?? Irradiator ALDORADO 8. After irradiation. KB cell lines(3×104cells/ml) were exposed to 2㎍/ml of bleomycin or cisplatin for 1 hour. The viable cells were determined by MTT assay for each radiation dose and/or each drug at the 4th day. And they were compared to control values. The obtained results were as follows: 1. The slope of the surviving curve after irradiation of 2, 4, 6, 8, 10Gy on KB cell line was relatively steep. 2. There was no significant difference between the cytotoxicity of bleomycin compared to control group. But, there was significant difference between the cytotoxicity of cisplatin compared to control group. And the cytotoxicity of cisplatin was greater than that of bleomycin on KB cell line. 3. There were significant differences of surviving fractions after irradiation of 2Gy and 10Gy with 2㎍/ml of bleomycin compared with the groups of irradiation only on KB cell line. 4. There were significant differences of surviving fractions after irradiation of 2, 4, 6, 8, 10Gy with 2㎍/ml of cisplatin compared with the groups of irradiation only on KB cell line. 5. There was significant difference of surviving fraction between groups after irradiation of 10Gy with 2㎍/ml of bleomycin and cisplatin.

디지털 치근단방사선영상에 관한 시각 특성 연구

고광준,최은숙 大韓口腔顎顔面 放射線學會 1999 Imaging Science in Dentistry Vol.29 No.1

Objectives: The purpose of this study was to evaluate the optimal distance and angle of observers by modulation transfer functions(MTFs) and receiver operating characteristics(ROCs). Material and Methods: Digital periapical radiograms were taken from 43 patients who have dental diseases(19 patients : dental caries, 12 patients : periapical lesions, 12 patients : periodontal diseases). Segmental images(4×4cm) were evaluated by 4 MTFs and ROC analysis. Results: The optimal distance(magnification) using MTF by Mannos & Sakrison was 12.97, and those by Nill, Ngan and Rao were 8.39, 4.78, 5.84 respectively. The optimal distance obtained from 4 radiologists by ROC analysis was 32cm(Az value : 0.89), and it was 40cm(Az value : 0.78) from 4 non-radiologists. There were significant differences of Az values between 4 radiologists and 4 non-radiologists at 24, 32 and 40cm (P<0.05). No significant differences of optimal distances were observed using 4 MTFs among +20, +10, 0, -10, -20 degrees(P>0.05). The optimal angle obtained from 4 radiologists by ROC analysis was +20 degree(Az value : 0.91), and no significant differences of Az value were observed among +20, +10, 0, -10 and -20 degrees(P>0.05). The optimal angle obtained from 4 non-radiologists by ROC analysis was 0 degree(Az value : 0.81), and no significant differences of Az values were observed among +20, +10, 0, -10 and -20 degrees(P>0.05). And there was significant difference of Az value between 4 radiologists and 4 non-radiologists at +20 degree(P<0.05), but no significant differences of Az values were observed among +10, 0, -10 and -20 degrees(P>0.05).(J Korean Oral Maxillofac Radiol 1999:29:259-272)