수술방법에 따른 액취증의 합병증 비교

김형우, 이의태 충북대학교 의과대학 충북대학교 의학연구소 2012 忠北醫大學術誌 Vol.22 No.1

연구목적 : 액취증은 겨드랑이에서 암내라고 불리는 특징적인 냄새를 내는 증상으로 비교적 흔하면서 환자에게 사회적, 정신적으로 많은 괴로움을 주는 질환이다. 이러한 액취증을 치료하기 위해 과거로부 터 수술적 절제술이 많이 시술되어 왔다. 하지만 불행하게도 수술적 절제술은 여러 가지 합병증이 보고 되고 있다. 현재, 액취증을 치료하기 위해 흡입술이 도입되면서 기존 치료방법과 효과와 만족도에 대한 비교의 필요성이 대두되어 왔다. 대상 및 방법 : 2005년 7월부터 2009년 3월까지 충북대학교병원 성형외과에서 액취증 일차 수술을 한 환자는 총 24명(남자 15, 여자 9)으로 이중 수술적 절제술이 8명, 흡입술이 16명이었다. 추적은 의무기록 검토 및 전화통화를 통한 설문으로 이루어 졌으며, 시술을 받은 24명의 환자중 수술적 절제 술 8명 중 7명(87.5%), 흡입술 16명 중 10명(62.5%)과 인터뷰가 이루어 졌다. 나머지 환자들은 수 신거부, 전화번호변경 등으로 추적하지 못했다. 인터뷰가 이루어진 17명의 환자들은 최소 10개월(평균 27.3개월) 간의 추적기간을 거쳤다. 액취제거에 대한 각 시술의 효과는 매우좋음, 좋음, 보통, 나쁨, 시술에 대한 만족도는 매우만족, 만족, 보통, 불만족 이렇게 각각 4단계로 분류하였다. 결과 : 효과에 대해서 수술적 절제술을 시행한 환자군에서는 매우좋음 4명(57.1%), 좋음 3명(42.9%) 으로 모두 좋음 이상의 답변을 하였고 흡입술을 시행한 환자군에서는 매우좋음 1명(10%), 좋음 5명 (50%), 나쁨 4명(40%)으로 답변을 하였다. 만족도에 대해서 수술적 절제술을 시행한 환자군 중 5명 (71.4%)이 만족 이상을 답변하였고, 흡입술을 시행한 환자군 중 4명(40%)이 만족 이상을 답변하였다. 합병증으로 수술적 절제술의 경우 과색소침착을 동반한 경계부위 조직괴사 및 과색소침착, 상처개열, 혈 종 각 1명으로 나타났고(총 3/7, 42.9%), 흡입술에서는 어떠한 합병증도 발견되지 않았다(0%). 결론 : 수술적 절제술 환자의 효과 및 만족도가 더 높지만 합병증이 흔한 것으로 나타났으며 흡입술의 경우 합병증은 없지만 효과 및 만족도가 떨어지는 것으로 나타났다. 이에 따라 두가지 방법 어느 하나 가 다른 하나에 비해 반드시 우월하다고 볼 수는 없는 것으로 보이며 환자와 상황에 따라서 알맞은 방 법을 쓰는 것이 좋을 것으로 생각된다.

N₂O 가스로 열산화된 게이트 산화막의 전기적 특성

김태형,김창일,최현식,장의구,서용진,이철인 중앙대학교 생산공학연구소 1992 생산공학연구소 논문집 Vol.1 No.2

미래의 ULSI 소자의 게이트 산화막으로 이용하기 위하여 N₂O 가스 분위기에서 기존의 전기로를 이용한 실리콘의 열산화에 의해 N₂O 산화막을 형성하였고, MOS 소자를 제작하여 전기적 특성을 고찰하였다. 900℃에서 90분간 산화한 N₂O 산화막의 경우, 플랫밴드 전압(??), 고정전하밀도(??)와 플랫밴드 전압의 변화량(??)은 각각 0.81 [V], ?? [??]와 80∼95[mV]를 나타내었다. N₂O 산화막의 전기전도기구는 저전계 영역에서는 Fowler-Nordheim 터널링, 고전계영역에서는 Poole-Frenkel 방출이 지배적으로 나타났고, 절연파괴전계는 16 [MV/㎝]로 높게 나타났다. 따라서 N₂O 산화로 형성된 게이트 산화막이 ULSI 소자의 게이트 유전체로 응용이 가능하리라 생각된다. In order to applicate gate insulators in future ULSI devices, electrical properties was investigated in MOS device with N₂O oxide grown by thermal oxidation using conventional furnace in N₂O ambient. For the sample oxidized at 900℃ for 90 min, Flatband voltage(??), fixed charge density(??) and shifts of flatband voltage(??) after BTS was obtained 0.81 [V], ?? [??] and 80∼95[mV], respectively. The dominant conduction mechanism of N₂O oxide appeared to be Fowler-Nordheim tunneling in the low electrical field region(4-6 [MV/㎝]) and to be Poole-Frenkel emission in the high electrical field region( 9 [MV/㎝] or above). Dielectrics breakdown fields of N₂O oxide appeared about 16 [MV/㎝]. These results suggest that the N₂O oxides is a promising candidate for ultrathin gate dielectric for MOS ULSI applications.

장중첩증을 동반한 맹장 지방종 1예

홍의실,나병규,김민옥,유일영,채지영,채희복,윤세진,이상전,송형근,박길선,정현용 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.2

대장 지방종은 주로 우측 결장에 호발하고 특히 회맹판 부위와 맹장 부위에 호발한다. 또한 50~60대에 빈도가 높고 증상이 있는 환자에서 장중첩증이 높게는 40~50%에서 보고되고 있어 성인 장중첩증의 원인으로 중요한 비중을 차지한다. 특히 성인 장중첩증 및 장폐쇄의 중요 원인인 악성 종양과 임상 양상이 유사하여 감별진단이 중요하다. 저자들은 반복적인 복통을 주소로 내원한 환자에서 맹장의 4×5㎝의 점막하 지방종이 말단 회장부위와 반복적인 장중첩중이 발생했던 1례를 부분 절제술로 치료하여 양호한 임상 경과를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Lipomas are one of the most common benign nonepithelial tumors of the colon which are often detected incidentally by radiologic investigation or on operation. These tumors are usually without specific symptoms. Colonic lipomas occur most often in the right colon, particularly in the ileocecal valve and the cecum. Most patients are asymptomatic. but tumors larger than 2 cm tend to produce a change in bowel habit. abdominal pain. rectorrhagia and complications including luminal obstruction or intestinal intussusception. Diagnosis can be made by colonoscopy abdominal CT. MRI, or barium enema. We report a case of lipoma of the cecum that originated in the submucosa and presented as a intussusception in a 50-year-old woman with a brief review of the literature.

Spray Dryer를 이용한 배연탈황의 수치모사

오의경,이형근,김선근,장순희 중앙대학교 생산공학연구소 1995 생산공학연구소 논문집 Vol.4 No.1

반건식 배연탈황공정에서 사용되는 spray dryer absorber(SDA)에 대한 수치모사를 행하였다. 기본 방정식으로는 기체와 액적의 각 성분들의 물질수지식, 에너지수지식과 액적의 운동 방정식등이 포함되었다. 만들어진 모델은 대부분이 기존의 SPRAYMOD-M보다 실제의 pilot plant date를 더 잘 모사하였다. 실제 pilot plant에서 사용되는 값의 범위 내에서 선정된 공정변수가 SDA의 성능에 미치는 효과를 계산하고, 이를 SO₂의 흡수속도, 배연기체의 체류시간, 그리고 액적의 건조시간 및 속도 등에 의해 검토하였다. 또 SO₂제거율을 두 개의 독립된 공정 변수의 함수로 구하였으며, 그 결과를 3차원 또는 2차원의 등가선으로 표시하여 SDA의 설계에 쉽게 적용될 수 있도록 하였다. A mathematical model has been developed for simulating the spray dryer absorber (SDA) used in semi-dry flue gas desulfurization process. Fundamental equations include the component mass and heat balances in both gas and droplet phases and the equation of motion for a single droplet. The model developed described the pilot-plant data much better than the existing SPRAYMOD-M model. The effect of the process variables, whose values were chosen within the operation limits of the actual pilot plants, on % SO₂removal or conversion of the sorbent were calculated, and discussed in terms of SO₂absorption rate, the residence time of flue gas, the velocity and drying time of droplets. Finally, the % SO₂removal was calculated with two independent process variables and the results were shown on three-dimensional or two-dimensional diagrams with the lines of constant % SO₂removal, so that they can be easily applied to preliminary design of the SDA.

악관절 수술후 안면신경 손상에 대한 임상적 연구

주재동,이의웅,김준배,박광호,김형곤 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.4

Authors have studied retrospectively the facial nerve injury after TMJ surgery through the preauricular approach routine. The study material used was 4 patients of all 113 patients who were diagnosed as internal derangement and have been operated from March 1989 to February 1991 in Youngdong severance hospital, and were induced postoperatived facial nerve injury. The patient group who had the postoperative injured facial nerve was recognized degree of injury using the diagnostic method, Electromyography(EMG) and Nerve conduction test(NCT) which are used widely at present and was treated as conservative care and we identified the recovery time as the same method. The results as follows : 1. The meticulous care and precious surgical technique are needed in both operation and postoperation. During the TMJ surgery, the excessive retraction of the flap and frequent use of nerve stimulator and electric surgical knife should be avoided as possible and postoperative hematoma and swelling should be minimized. 2. The 4 patients were experienced with the postoperative facial nerve injury of all 133 patients who had been operated the TMJ surgery through the routine preauricular approach on our hospital. And the incidence of postoperative facial nerve injury happened was about 0.3% and its incidence was relatively low comparing with any other previous reports. 3. EMG and NCT were considered as useful methods which can diagnose the nerve injury objectively and identified the effect of treatment and recovery time. 4. The faical nerve-injured patients who were induced postoperatively after TMJ surgery, were diagnosed as second-degree nere injury through the EMG and NCT. And the patient group was treated well as conservative physical therapy for about 2 to 4 months.

최근 6년간 연세의료원에서 경험한 한국인 안면골 골절에 대한 임상적 연구

권준호,이충국,이의웅,민우석,윤중호,박형식 大韓顎顔面成形外科學會 1989 Maxillofacial Plastic Reconstructive Surgery Vol.11 No.1

This is a series of continuing research on facial bone fractures of Koreans worked by Dept. of Oral and Maxillofacial surgery, Dental College of Yonsei University, Seoul, Korea, since 1972. The study was based on a series of 630 patients with facial bone fractures treated as in patient at Yonsei Medical Center, Yonsei University, during the period of Jan. 1982 through Dec, 1987. The results obtained are as follows: 1. The ratio of Men to Women was 4.3 : 1, and admissions for facial bone fractures have been increased year after 1984. 2. The age frequency was highest in the third decade(38.3%). and fourth, second, fifth decade in orders. 3. The traffic accident was the most frequent cause of facial bone fractures(51.3%). 4. The most common location of facial bone fractures was the Mandible(35.3%), and Zygoma complex(29.8%), Nasal bone(15.0%), Maxilla(11.0%) were next in order of frequency. 5. In 291 patients of Mandible fractures, 226(77.7%) had fractures only in Mandible and 65(22.3%) had another facial bone fractures. The most frequent fracture site of mandible was the Symphysis(43.0%) and Angle(22.4%), and Simple fracture was the most frequent in type of fracture(66.9%). Intermaxillarty fixatin & Open reduction was major method of treatment(36.9%). 6. In 394 patients of Midface fractures 323(82.0%) had fractures only in Midface and 71(18.0%) had another facial bone fractures. The most frequent site of Midface fractures was zygoma complex & zygomatic arch(42.7%), and Simple fracture was the most common type of fractures. Observation(Maxilla :44.2%, Zygoma :51.0%) and Open Reduction(Maxilla :20.0%. Zygoma :23.5%) were the major method of treatment. 7. The frequency of Nasal bone fracture was about 1/5 of Midface fractures, and Closed Reduction(42.2%) was the major method of treatment. 8. The complication was reported in only 16 patients, and Malunion was the major complication. 9. Head(44.4%), Lower extrimities(14.5%) and Eye(12.3%) were injured commonly with facial bone fractures. 10. The elapsed time from injury to hospital was within 24 hours in 73.8% of patients, however 15.5% of patients arrived the hospital 72 hours after injury.

pH 5.5에서 재광화 용액의 포화도 변화가 인공 탈회된 법랑질의 재광화에 미치는 영향

곽영준,김의성,박성호,공형규,이윤,이찬영 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.5

초기 법랑질 우식의 경우 주위의 pH. 유기산의 종류 및 농도,치아의 무기질 및 유기질의 화학적 조성,불소의 농도,용액의 포화도등에 의해 영향을 받는다고 하였다. 본 연구에서는 lactic acid를 이용하여 법랑질을 인공 탈회시키고, pH 5.5인 포화도가 다른 세 가지 재광화 용액 (포화도 0.25,0.30, 0.35)으로 12일간 처리한 후,편광 현미경에서 얻은 상에서 탈회 깊이의 변화,우식 표면층 폭의 변화,무기질의 양적 변화를 Photoshop, Image pro plus, Scion Image, Excel을 이용하여 비교,분석하였다. 1. pH 5.5 에서 재광화 용액의 포화도가 증가할수록 우식 표면층의 폭은 증가하였다. 2. pH 5.5 에서 l 군의 경우 우식 부위에 전반적으로 재광화가 일어났으나,3군의 경우 우식 표면층에서만 재광화의 양상이 뚜렷하게 나타났고, 2군에서는 1군과 3군의 중간적인 양상이 나타났다. 한편,3군의 경우 1, 2 군보다 우식 표면층의 폭이 유의하게 증가하였다. 결론적으로 본 실험의 조건에서 포화도가 가장 낮았던 군에서는 우식 표면층에서 우식 섬부까지 전반적으로 재광화가 일어난 반면,포화도가 높아질수록 우식 표면층의 폭은 증가하였으나 우식 심부에서는 큰 변화를 보이지 않는 양상이 나타났다. The purpose of this study is to observe and compare the remineralization tendencies of artificially demineralized enamel by remineralization solutions of different degree of saturations at pH 5.5, using a polarizing microscope and computer programs (Photoshop, Image pro plus, Scion Image, Excel). For this study, 36 sound permanent teeth with no signs of demineralization, cracks, or dental restorations were used. The specimens were immersed in lactic acid demineralization solution for 3 days in order to produce dental caries artificially that consist of surface and subsurface lesions. Each of 9 or 10 specimens was immersed in pH 5.5 lactic acid buffered remineralization solution of three different degrees of saturation (0.25, 0.30, 0.35) for 12 days. After the demineralization and remineralization, images were taken by a polarizing microscope (× 100). The results were obtained by observing images of the specimens, and using computer programs, the density of caries lesions were determined. In conclusion, in the group with the lowest degree of saturation, remineralization occurred thoroughly from the surface to the subsurface lesion, whereas in the groups with greater degree of saturation showed no significant change in the subsurface lesion, although there was corresponding increase in the remineralization width on the surface zones.

소화성 궤양에서 삼제 병합 요법의 저용량에 의한 Helicobacter pylori 제균률과 궤양 치유효과

김예리,박봉안,이재동,이종혁,김인숙,박형석,진춘조,김상윤,박의우 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Helicobacter pylori is the major cause of histologic chronic gastritis and is strongly associated with peptic ulcer disease, gastric cancer and lymphoma. Several recommendations for the management of the Helicobacter pylori infection have been developed. However, there has been no clear therapeutic regimen for the optimal treatment of Helicobacter pylori infection. This study was desinged to evaluate the eradication rate and the ulcer healing rate of the triple regimen with low-dose clarithromycin(0.5g/day) in peptic ulcer patients. Forty three patients with gastric ulcer(n=15) and duodenal ulcer(n=28) were enrolled. The patients were treated either with omeprazole 20mg b.i.d. amoxicillin 0.5g b.i.d. and clarithromycin 250mg b.i.d. (low-dose regimen group, n=29) or with omeprazole 20mg b.i.d., amoxicillin 1.0g b.i.d. and clarithromycin 0.5g b.i.d.(high-dose regimen group, n= 14) for 2 weeks. After 4 weeks, the patients were evaluated for the eradication of Helicobacter pylori and the healing of ulcer. And gastritis scores according to the Sydney system were evaluated before and after 4 weeks from the end of the triple regimen. There was no significant difference in the eradication rate and the ulcer healing rate between the low-dose regimen group, group and the high-does regimen group. In the low-does regimen group, the mean initial scores of chronic inflammation and activity were decreased after the eradication of Helicobacter pylori. In conclusion, the low-dose triple regimen is as effective as the high-dose triple regimen on the eradication of Helicobacter pylori and the ulcer healing rate in peptic ulcer disease.

급냉 응고된 Al-Li-Cu합금의 열처리, 미세조직 및 기계적 성질에 관한 연구(I)

許明日,南勝義,李範圭,羅亨用,金錫胤 弘益大學校 1988 弘大論叢 Vol.20 No.2

Effect of aging condition on the microstructure and hardness properties of Al-3Li, Al-3Li-2Cu, Al-3Li-2Cu-0.3Zr have been studied. The alloy ribbons have been prepared by means of Single Roll Melt Spinning by rapid solidification technique. In rapidly solidified Al-3Li-2Cu, Al-3Li-2Cu-0.3Zr alloy ribbons show the icosahedral intermetallic compound of five-fold symmetry which is placed in cell-bound-ary and matrix. In the matrix precipitated fine δ'(Al₃Li) phase. Heat-treated at 250℃ 1hr. In this condition, δ'(Al₃Li) phase started decompose. The icosahedral intermetallic compound has been grown. When heat-treated at 300℃ 1 hr, the δ' phase has been decomposed all. In the matrix, icosahedral intermetallic compound has been grown greatly. The micro-hardness has been obtained more high Al-Li-Cu-(Zr) alloy than Al-Li alloy. Strength-hardended phenomena showed to solution hardning by the addition of Cu. When the heat-treated at 250℃ 1 hr, in the alloy of Zr addition, delayed decomposed δ' phase. In the case, micro-hardness gradually decreased. When the heat-treatment have done at 300℃ 1 hr, the micro-hardness has been decreased because δ' phase decomposed all.

일측성 질폐쇄 및 동측 신장 무발생을 동반한 중복자궁 2예

윤일영,여소진,김형문,김정식,김태희,이해혁,남계현,이권해,김준모,김민의 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Uterus didelphys with unilateral obstructed hemivagina and ipsilateral renal agenesis usually presents after menarch with progressive abdominal pain during menses secondary to hematocolpos, and indeed a very rare congenital anomaly due to Mullerian duct malformation. An accurate and prompt diagnosis is of importance to permit treatment and to assure the future fertility of the patient. Pelvic ultrasound, physical examination and pelvic MRI established a diagnosis of hematometracolpos secondary to uterus didelphys with unilateral imperforate hemivagina. An incision in the vaginal septum allowed drainage of the hematocolpos, providing relief of the patients symptoms. We report two case of uterus didelphys with obstructed hemivagina with brief review of the literature.