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      • KCI등재후보

        The level of urinary aflatoxin M1 in Korean adults

        Yong-Dae Kim1, Hyojin Kwon, Sun-In Moon, Sang-Yong Eom, Jung-Duk Park, Byung-Sun Choi, Seok-Joon Sohn, Young-Seoub Hong, Ho Kim, Ho-Jang Kwon, Ji-Ae Lim, Hae-Jung Yoon, Gwang-Jin Kim, Heon Kim 충북대학교 동물의학연구소 2012 Journal of Biomedical and Translational Research Vol.13 No.3

        Competitive ELISA methods were used to measure the level of aflatoxin M1 (AFM1) from urine in 1008 Korean adults. Subjects were selected by random sampling in all areas of Korea, except Cheju-do. The recovery rate of AFM1 using this method was 105% (73-124%). The geometric mean of urinary AFM1 in all subjects was 3.43 pg/mL (3.67 ng/g creatinine). The level of AFM1 in males was statistically higher, compared with female subjects. However, the levels of AFM1 did not differ according to age. Subjects in Chungbuk-do showed the highest urinary AFM1 concentration, whereas subjects in Kyeongnam-do showed the lowest concentration. Assuming an excretion rate of 5%, this AFM1 excretion corresponds to approximately 0.1 microgram/day in Korean adults.

      • 最近 十年間 우리나라 主要死因의 變化推移에 關한 硏究

        金得祚,尹太永,崔重明,朴淳永,柳東俊 慶熙大學校 1995 論文集 Vol.24 No.-

        The authors have made and attempt to examine the transition of the leading causes of death in Korea recently since 1984 by analytically reviewing the annual statistical data on the causes of death for the latest ten years reported mainly from the National Statistical Office and other informative materials. The results were summarized as follows: 1. After the inverting period of the 1970s and early 1980s changing remarkably from the communicable to the non-communicable disease, the leading causes of death were changed to the chronic degenerative diseases such as circulatory disease and malignant neoplasms recently. 2. With the particularly increasing deaths due to the unintentional accidents since the mid-1980s, circulatory disease, malignant neoplasms, and accidents became the three leading causes of death, and accounted for about 66.5 percent of the total deaths in 1993. 3. Concerning the sex-specific leading causes of death, currently they were malignant neoplasms, accidents, cerebrovascular disease, chronic liver disease, and heart disease in males, and cerebrovascuar disease, malignant neoplasms, heart disease, accidents, and hypertensive disease, malignant neoplasms, heart disease, accidents, and hypertensive disease in females in that order respectively. 4. As to the leading causes of death by the age-groups, they were congenital anomaly and infectious disease at infantile age; accidents and unintentional injury at ages 1-39year: malignant neoplasms, circulatory disease, and chronic degenerative disease at ages 40-69years; and circulatory disease, senility and other chronic degenerative disease at ages 70 and over respectively. 5. In reviewing the transition of the leading causes of death, communicable diseases formidably prevailed for the past decades were rapidly decreased recently, and chronic degenerative disease, So-called, "Chronic Illness" such as circulatory disease, malignant neoplasms, and chronic pulmonary disease are in tendency of continuous increase year by year. Although chronic liter disease seems to be stationary in incidence now-a-days, additionally, its level of death is still relatively high. And the death rates due to all kinds of accidents are remarkably increasing. Overall, accidents and unintentional injuries were the third leading cause of death and accounted for about 15 percent of the total deaths.

      • KCI등재

        한국형 우울장애 약물치료 알고리듬 2006 (Ⅲ) : 정신병적 양상을 동반한 주요우울삽화

        김원,박원명,서정석,민경준,석정호,전덕인,전현태,이상열,송해철,홍진표,한국형 우울장애 약물치료 알고리듬 2006 연구그룹 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

        Objectives : Since the publication of Korean Medication Algorithm Project for Major DepressiveDisorder (KMAP-MD) in 2002, there has been a substantial need for a revision due to rapid progress in the pharmacological management of depressive disorder. We revised KMAP-MD 2002 and developed the Korean Medication Algorithm Project for Depressive Disorder (KMAP-DD) 2006. Methods : We developed a questionniare for surveying the opinion of experts on pharmacotherapy of depressive disorder. The questionnaire consisted of 4 parts ; 1) treatment of non-psychotic depressive disorder, 2) treatment of psychotic de-pressive disorder, 3) treatment according to clinical subtypes and drugs choice considering adverse effects, and 4) treatment of depressive disorder in women. The questionnaire was completed by the review committee consisting of 101 experienced Korean psychiatrists. It is composed of 22 questions, and each question includes 54 sub-items. We classified the expert opinionto 3 categories (the first-line, the second-line, or the third-line) by χ²-test. Results : For depressive disorder with psychotic features, most reviewers prefer the combination of antidepressant and atypical antipsychotics. Electroconvulsive therapy and the combination of antidepressant and typical antipsychotics were the second-line treatment. Among antidepressants, venlafaxine was the most preferred, and SSRI and mirtazapine followed. Among atypical antipsychotics, quetiapine, risperidone and olanzapine were the most preferred, in this order. In patients who have no response to the first-line treatment, many reviewers recommended switching to another antidepressant or adding another atypical antipsychotics Conclusion : For severe depressive disorder with psychotic features, the combination of antidepressant and atypical antipsy-chotics was preferred for the first-line treatment. These results suggest that the medication strategies of depressive disorder are rapidly changing and reflects the recent studies and clinical experiences.

      • 日本語 會話文에 나타난 敬語使用 分析

        김덕준,이정아 경원전문대학 2002 論文集 Vol.24 No.-

        We have analyzed the speakers' mental intentions, the situations, the roles of scenes and so on from some viewpoints by the study of verbal expression for respect and politeness by means of the analysis on the colloquial language in Japanese modern novels. The abstract of the analysis result is that the use of honorifics is a means of controlling mental sense of distance besides basic verbal means for paying one's respect to others. Additionally, the honorifics use seems to be generalized as an intention for giving good image of oneself and expressing politeness to others rather than the paying one's respect to them.

      • On-line 학습 신경회로망을 이용한 열간 압연하중 예측

        손준식,이덕만,김일수,최숭갑 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

        In the face of global competition, the requirements for the continuously increasing productivity, flexibility and quality(dimensional accuracy, mechanical properties and surface properties) have imposed a major change on steel manufacturing industries. Indeed, one of the keys to achieve this goal is the automation of the steel-making process using AI(Artificial Intelligence) techniques. The automation of hot rolling process requires the developments of several mathematical models for simulation and quantitative description of the industrial operations involved. In this paper, a on-line training neural network for both long-term learning and short-term learning was developed in order to improve the prediction of rolling force in hot rolling mill. This analysis shows that the predicted rolling force is very closed to the actual rolling force, and the thickness error of the strip is considerably reduced.

      • X선 촬영인자의 변화에 따른 영상의 주관적인 화질 평가

        권덕문,박명환,김성환,박종삼,이준일,남효덕 대구보건대학 2001 대구보건대학 論文集 Vol.21 No.-

        In this study, visual recognition of X-ray images were estimated using hawlet charts. The resolution has achieved excellent result when densities of film were 1.0~1.5. The more thickness of object was increase, the more the resolution was decrease, because scattered X-ray were increased. The more distance of object to film was increase, the more the resolution was decrease, because groedel effect. The more focal spot size was increase, the more resolution was decrease, because unsharpness was increase. The more field size was increase and grid ratio was decrease, the more resolution was decrease, because scattered X-ray were increase. As a result, we could to improve image quality by determination of resolution according to Radiography parameters. And, we proved that hawlet charts were useful for estimate of image quality and set up x-ray radiography.

      • KCI등재

        조중 삽화로 입원했던 환자의 재평가 : 혼재성 삽화 진단의 가능성

        전덕인,김경란,이 은,손상준 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

        Objective : Mixed states are difficult to define precisely and to recognize accurately. Moreover, the DSM-IV criteria for diagnosis of a mixed episode might be too restrictive. The purpose of this study was to investigate the possibility of a mixed episode in bipolar inpatients hospitalized with DSM-IV manic episodes using the Cincinnati criteria, which is a broader criteria compared to DSM-IV. Methods : Inpatient charts of manic patients were carefully evaluated to determine the presence of depressive symptoms in the Cincinnati criteria. The probable mixed patient group was compared with the definitely manic patient group on demographic and clinical variables. The predictability of depressive symptoms for a mixed episode was assessed. Results : Twenty-one out of 101 manic inpatients were possibly diagnosed as mixed episodes. They showed more psychiatric family history, comorbid personality disorder and suicide attempts. Two symptoms (suicidal ideation and helplessness or hopelessness) had good positive predictive value. Conclusion : Diagnosis of a mixed episode can be increased with careful interview and by using a broader diagnostic criteria. The presence of suicidal ideation and helplessness or hopelessness may suggest a mixed state.

      • 대퇴골 전자간 골절을 동반한 고령의 환자에서 시행한 슬관절 전치환술

        고덕환,김동헌,김규현,신주용,양준호 건국대학교 의과학연구소 2001 건국의과학학술지 Vol.11 No.-

        Purpose: To analyze the clinical results of total knee arthroplasty In elderly patients who had arthritic knees and intertrochanteric fractures. Materials and Methods: From fan 1992 to March 1999, 27 cases of the patients with arthritic knees and associated intertrochanteric fractures were treated by total knee arthroplasties and we evaluated the patients by Knee Score of American Knee Society. Results: Flexion contracture was improved from 10.3 degree to 5.2 degree, KSS score was improved from 57.4 points to 78.6 points, authors' evaluation system score was improved from 50.3 points to 73.2 points. Conclusion: In elderly patients with arthritic knees and associated intertrochanteric fractures, total knee arthroplasty seemed to decrease the rehabilitation time and allow earl weight bearing, so provide an improvement in quality of life.

      • KCI등재

        방사형기저함수망을 이용한 열간 사상압연의 압연하중 예측에 관한 연구

        손준식,이덕만,김일수,최승갑 한국공작기계학회 2004 한국생산제조학회지 Vol.13 No.6

        A major concern at present is the simultaneous control of transverse thickness profile and flatness in the finishing stages of hot rolling process. The mathematical modeling of hot rolling process has long been recognized to be a desirable approach to investigate rolling operating practice and the design of mill equipment to improve productivity and quality. However, many factors make the mathematical analysis of the rolling process very complex and time-consuming. In order to overcome these problems and to obtain an accurate rolling force, the predicted model of rolling force using neural networks has widely been employed. In this paper, Radial Basis Function Network(RBFN) is applied to improve the accuracy of rolling force prediction in hot rolling mill. In order to verify and analyze the performance of applied neural network, the comparison with the measured rolling force and the predicted results using two different neural networks-RBFN, MLP, has respectively been carried out. The results obtained using RBFN neural network are much more accurate those obtained the MLP.

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