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적외선 흡수 분광법 및 DPC를 이용한 치과용 수복재의 광중합 거동 분석
정찬문,김중곤,최준호,장두옥,김경남,김광만 대한치과기재학회 1998 대한치과재료학회지 Vol.25 No.1
Mechanical properties of compomers would be obtained mainly by photopolymerization by visible light irradiation. Photopolymerization behavior of two commercial compomers was investigated by FT-IR spectral analysis and differential photocalorimetry(DPC). The results obtained were as follows: 1. From FT-IR analysis, it was found that the compomer products were photocured mainly by radical polymerizations of multifunctional methacrylate monomers. Final conversion values of the polymerizations after exposure to visible light for 60 sec were 67% for Dyract and 59% for Compoglass. 2. Upon exposure the compomers exhibited autoacceleration and autodeceleration, which are usually observed in bulk polymerizations of multifunctional monomers. 3. Dyract showed higher rate of polymerization and conversion of double bond than Compoglass.
Epstein-Barr virus(EBV)와 연관된 Nasal type T/Natural Killer(NK)-cell lymphoma 1예
지두현,최지호,성경제,문기찬,고재경 울산대학교 의과대학 1996 울산의대학술지 Vol.5 No.1
Nasal type T/NK-cell lymphoma는 병리조직학적으로 응고성 괴사가 동반된 혈관중심성 침윤을 특징으로하며 T-cell과 NK-cell 항원을 모두 표현하는 면역조직화학염색 소견을 보이는 매우 드문 피부 림프종으로서 EBV와의 연관성이 흔히 보고되고있다. 저자들은 42세 여자에서 발생한, 전신적인 홍반성 구진, 판, 결절의 임상양상을 보였으며 피부 병변에서의 EBV-encoded RNA(EBER)에 대한 in situ hybridization상 양성소견을 보였고 전산화단층촬영, 골주사, 갈륨주사 등의 검사상 비강, 위장관 및 다른 내부장기 침범소견은 보이지 않아서 피부에만 국한된 경우로 사료되는 nasal type T/NK-cell lymphoma 1예를 보고하는 바이다.
문두찬(Doo Chan Moon),현명기(Myung Ki Hyun),권경술(Kyung Sool Kwon),정태안(Tae Ahn Chung) 대한피부과학회 1989 대한피부과학회지 Vol.27 No.2
Involucrin is a recently recognized structural component of mature squamous epithelial cells and is considered as a marker of normal eratinocyte differentiation and ma.turation. In this study peroxidase-antiperoxidase techniques were used to assess involucrin expression in histologic sections of normal skin and a variety of epidennal tumors including squamous cell carcinomas(25 cases), keratoacanthomas(11 cases), basal cell carcinomas(20 cases), trichoepitheliomas(5 cases), Howens diseases(12 cases), arsenic keratoses(10 cases), actinic keratoses(10 cases) and Pagets diseases(2 cases). The results were as follows : l. In normal skin, the upper third of the viable epidermis showed diffuse cytoplasmic staining for involucrin. In hair follicles, the lower area of inner root sheath and inner area of the outer root sheath stained positively. The sebareous glands did not stain, but the ducts of sebaceous glands were positive. 2. Keratoacanthomas showed a relatively homogeneous staining pattern for inirolucrin ', all cells except basal cells stained with mild to moderate intensity. In contrast, squamous cell carcinomas disclosed a highly irregular involucrin staining pattern with marked variation in staining intensity from cell to cell. 3. Basal cell carcinomas were negative for involucrin except squamous horn cysts, and the epidermis overlying basal cell carcinomas showed the field effect, that is, the epidermis overlying the tumors exhibited diffuse, homogeneous positive staining of cells in all layers of the epidermis. 4. ln trichoepitheliomas, the involucrin reactivity was negative as in basal cell carcinoma.s, but the field effect was not observed. 5. In Elowens disease, actinic keratosis, arsenic keratosis and Pagets disease, the positivit.y for involucrin staining extended deeper into the stratum malpighii than was observed wit,h normal epidermis. And areas showing irregular patchy pattern of involucrin staining were considered to have the potentiality of malignant invasive change much more than the negative or homogeneous areas. Paget's cells were negative for involucrin as the adjoining keratinocytes in the lower portion af epidermis.
장호선,문두찬,권경술,정태안 ( Ho Sun Jang,Doo Chan Moon,Kyung Sool Kwon,Tae Ahn Chung ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.4
N/A Clinical and Histopathological Observation of Confluent and Reticulated Papillomatosis Ho Sun Jang, M.D., Doo Chan Moon, M.D., Kyung Sool Kwon, M.D., Tae Ahn Chung, M.D. Department of Dermatology, College of Medicine, Pusan National University, Pusan, Korea Confluent and reticulated papillomatosis is a rare but clinically distinct dermatosis of which the etiology is unknown. We observed the clinical and histopathological findings of 14 patients of confluent and reticulated papillomatosis who had visited Pusan National University Hospital, and studied mycologically Pityrosporum orbiculare. The results were as follows : 1. The mean age of onset was 17.7 Years and the most common site of initial involvement was epigastrium(57.1%), and the most common sites of involvement were abdomen(85.7%), and back(85.7%). 2. Positive KOH/Parker ink direct smears were observed in 9 cases, and they were treated with oral and topical antifungal agents. Six out of the patients were responsive to these treatment. 3. Skin biopsy was performed in 13 patients. The major histologic features were hyperkeratosis, focal acanthosis, papillomatosis, parakeratosis, slight atrophy of stratum malpighiii, decreased granualr cell layer, hypermelanosis of basal cell layer, and slight perivascular infiltrate of mononuclear cells. Periodic acid-Schiff stain showed Pityrosporum orbiculare yeasts in the stratum corneum in 7 cases. 4. The cultrued Pityrosporum orbiculare colonies were inoculated on the inner ear surface of 5 rabbits, and one week after inoculation, thick yellowish scaly crusts were seen in 3 of 5 rabbits. Therefore, we believe that Pityrosporum orbiculare may play an important role in the pathogenesis of confluent and reticulated papillomatosis. (Kor J Dermatol 29(4) : 471-480, 1991)
장호선,이장수,문두찬,권경술,정태안 ( Ho Sun Jang,Jang Soo Lee,Doo Chan Moon,Kyung Sool Kwon,Tae Ahn Chung ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.4
A Case of Acute Febrile Neutrophilic Dermatosis Associated with Ulcerative Colitis Ho Sun Jang, M.D., Jang Soo Lee, M.D.*, Doo Chan Moon, M.D., Kyung Sool Kwon, M.D., Tae Ahn Chung, M.D. Department of Dermatology, College of Medicine, Pusan National University, Department of Dermatology, Pusan Medical Center*, Pusan, Korea We report a case of acute febrile neutrophilic dermatosis associated with ulcerative colitis occurred in a 58-year-old woman who showed well-demarcated, painful, erythematous papules, nodules, and plaques on the face, posterior neck, and both upper and lower extremities. The patient also experienced frequent diarrhea and intermittent bloody stool for about 10 years. Laboratory findings revealed polymorphonuclear leukocytosis, elevated erythrocyte sedimentation rate, and occult blood in stool. Findings of sigmoidoscopy, barium enema, and rectal biopsy were consistent with diagnosis of ulcerative colitis. Skin biopsy from the lesion on the posterior neck showed dermal edema resulting in subepidermal blisters and a dense inflammatory cell infiltration composed predominetly of polymorphonuclear leukocytes and a few mononuclear cells in the dermis. Biopsy from the lesion on the right shin revealed a moderate inflammatory cell infiltrate in the septa of the subcutaneous fat layer, composed chiefly of the lymphohistiocytes and a few eosinophils. The symptoms and signs responded well to orally administered prednisolone and sulfasalazine. This is a very rare case of acute febrile neutrophilic dermatosis with which ulcerative colitis was associated. (Kor J Dermatol 29(4) : 522-528, 1991)