만성 신부전을 동반한 Laurence Moon-Bardet Biedl 증후군 1례

박래경,이동환,문철,김은미,Park Lae Kyong,Lee Dong Hwan,Moon Chul,Kim Eun Mi 대한소아신장학회 1998 Childhood kidney diseases Vol.2 No.2

The Laurence Moon-Bardet Biedl syndrome is characterized by obesity, mental retardation, visual impairment with retinitis pigmentosa, polydactyly, hypogonadism and renal manifestations. We experienced an 11 years old female with Laurence Moon-Baret Biedl syndrome associated chronic renal failure. She was diagnosed to have LMB syndrom according to the clinical manifestations of polydactyly on hands and feet, mental retardation, obesity, retinitis pigmentosa and chronic renal failure. She is on maintenance hemodialysis now.

지난 2년간의 학회지 "신경정신의학" 심사 평가보고

김찬형,김세주,김도관,김성곤,박원명,송동호,박용천,이영문,오강섭,정영철,이상열,김주한,이동영,이헌정,함병주,김율리,김문두,김정진,이강욱,천근아,김재진,홍진표,홍승철 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.6

[논문]부산 시내 터널 내 총분진 농도 조사

구동철,문지용,정기호 부산대학교 환경문제연구소 2004 環境硏究報 Vol.22 No.-

The Survey of Dust Levels in Tunnels Located in Busan Metropolitan City

용접공들의 망간 폭로와 건강장해에 관한 연구

문덕환,강동묵,손병철 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : In order to evaluate the degree of manganese exposure and its health hazards effect on welders in manufacturing industry. Methods : The author measured airborne, blood and urine concentrations of manganese and blood chemistry, and also observed clinical symptoms and signs on 60 welders for case and 60 non-welders for control working in manufacturing industry by age maching method. Results : The geometric means of blood and urine concentrations of manganese were 1.13±1.38 ㎍/㎗ and 2.52±1.37㎍/ℓ for Welders group, 1.09±1.68 ㎍/㎗ and 1.86±1.34 ㎍/ℓ for Non-welders group. Airborne concentration of manganese was 0.15±1.66㎎/㎥ for exposured group, and the urinary mean concentration of manganese was statistically significant difference between exposured and non-welders group (P<0.05). Clinical signs in welders group were palmomentle reflex(23.3%), tremor(20.0%) and grabellar sign(5.0%). Symptoms in welders group were fatigue(66.7%), amnesia(66,7%), excessive sweating(51.7%), nervousness(51.7%), general weakness(48.3%) and arthralgia(46.7%) and so on, and there was statistically significant difference compared to non-welders group(P<0.05). Manganese effects on blood chemistry were not observed. There were statistically significant correlation between manganese concent- ration in blood and urine(r=0.269), airborne and urine(r=0.601) and airborne and blood(r=0.268). Conclusion : The author suggest that further studies are followed to evaluate the health status of welders whose blood and urine manganese concentrations were below normal reference level, and to establish the questionnaire and the diagnostic tools for early detecting the chronic manganese poisioning on welders.

중증 외상환자에서 염기 결핍수치의 유용성

문준동,김수진,문철규,최성혁,전정민,이성우,홍윤식 대한응급의학회 2001 대한응급의학회지 Vol.12 No.3

Background: This study's objective was to determine the prognostic value of the base deficit measured in the emergency department(ED) and to determine whether base deficit can provide information not provided by advanced injury scoring system. Methods: This study was a retrospective analysis of data collected for two years. Thirty-two severe trauma patients who were admitted to the Emergency Department of Korea University Hospital were included in this study. The patients were divided into two groups: the normal base deficit group(-3 mmol/L to 3 mmol/L) and the elevated base deficit group(>3 mmol/L). The base-deficit value, age, sex, head injury, organ failure rate, and survival were considered, and the also Revised Trauma Score(RTS), Acute Physiology And Chronic Health Evaluation(APACHE II), and Injury Severity Score(ISS) were measured. Result: The elevated base-deficit group showed a lower survival rate and a higher organ failure rate compared to the normal base deficit group. Logistic Regression showed a strong association between base deficit and mortality rate. Among the previous injury scoring Systems(RTS, APACHE II, ISS), base deficit had the strongest correlation with RTS. By using base deficit value and the RTS together, we obtained a higher positive predictive value than that obtained by using base deficit or RTS alone. Conclusion: The admission value of the base deficit in the ED is a useful tool in predicting the outcome in severe trauma patients, and it can be an adjunct to previous injury scoring systems. As an advanced injury scoring System is developed in the future, the base deficit may have some significant role.

홀스타인의 乳量 및 乳質에 대한 季節, 年度 및 年度 季節의 效果에 관한 硏究

文点東,姜奉泰,金哲旭 진주산업대학교 1983 論文集 Vol.21 No.-

This was conducted to determine the main effects and interaction of season and year on milk yield and quality on the basis of the data surveyed during 4 years from Jan. 1979 to Dec. 1982 at Gyeongnam area.(J Palnt) The data were analyzed by the least square method and the results obtained are summarized as follow: 1. Average daily milk yield and fat percentage were each 14.45㎏ and 3.44% in the overall observations surveyed. Average daily milk yield tended to decrease in the spring group and average fat percentage, in the summer group. 2. Average daily milk yield was significant(P<.05) in the effects of season and year x season and average fat percentage, in the all factors studyed. 3. Averge daily milk yield and fat percentage were significant(P<.01) in the all factors studyed. 4. Average monthly disqualified milk yield was 7488.83㎏ and average rate disqualified 1.47% in the overall observation surveyed. Average monthly disqualified milk yield generally tended to be higher in the 1980 year and the summer group. 5. Of the average monthly disqualified milk yields, average adification rate was 69.60% Average rate disqualified by testing specific gravity and the others were each 14.33 and 16.07% Average adification rate tended to be high in the winter group and average rate disqualified by specific gravity, in the spring group.

노인외상환자의 예후 인자

문철규,전정민,최성혁,문준동,이성우,홍윤식 大韓應急醫學會 1999 대한응급의학회지 Vol.10 No.2

Background: It has been documented that certain prognostic factors may affect the outcomes of the old aged victims by trauma. Considering that trauma is the sixth most common cause of death in people over the age of 65 years and there is a rapid growth of elderly population, it is paramount to understand the prognostic factors when dealing with geriatric trauma patients. Hypothesis and Goals: It can be hypothesized that the prognostic factors should be determined independently between populations being consisted of different races, countries, socio-economic states, cultures, or so on. Thus, the study was designed to evaluate the factors affecting the outcomes of elderly Korean trauma patients. Methods: One hundred forty six patients aged over 65 years were retrospectively reviewed, who visited the Emergency Center of Korea University from January, 1997 to June, 1998. Of 146 patients, 7 were excluded due to discharge against advice or transfer to the other hospitals. Parameters analyzed were age, sex, mechanism of injuries, body region injured, Injury Severity Score (ISS), previous medical illness, hospital morbidity, duration of hospital stay, and cost. Each patient was classified into improved or not-improved group depending on the outcomes, and young-old or old-old group depending on the age. The factors affecting the hospital stay in improved patients were analyzed in the parameters of previous medical illness, hospital morbidity, multiple injuries, ISS, and age. All statistical tests were conducted with two-tailed levels of 0.05. Results: Of 139 patients, the mean age was 74±7.1 years, mean ISS 9.3±7.26, mean hospital stay 27±27.1 days. Most commonly injured body region was the extremities due to fall from a level surface. Rate of previous illness showed 0.94 medical diseases per person and were aggravated after trauma in 39 patients (60.9%). Hospital morbidity rate was 0.46 incidents per person. There were no differences in age and duration of hospital stay between the improved and the not-improved group. Substantial differences were noted in affected body region, incidence of previous illness, and hospital morbidity between the groups (p=NS). Not-improved group had higher ISS(p<0.05). ISS, previous illness and hospital morbidity affected the duration of hospital stay in the improved group. Hospital stay was 40±25.1 days in patients with ISS over 6 while 6±8.6 days in those with ISS 5(p<0.05). Hospital stay in the improved was 26±26.9 days while 31±24.8 days in the improved old-old group (p=NS). Hospital stay in the young-old minor trauma (ISS5) patients with previous illness and hospital morbidity was 26±10.1 days while 4±7.3 days in those without previous illness and hospital morbidity (p<0.05). Conclusion: Previous medical illness and hospital morbidity, not age, are predictive of outcomes of geriatric trauma patients with respect to hospital stay. As most of the hospital morbidity was a trauma-induced aggravation of previous medical illness and hospital morbidity contributing poor outcomes can be potentially avoidable, routine aggressive care for the geriatric trauma patients with previous medical illnesses is needed.

돼지의 繁殖形質에 미치는 交配組合, 産次 및 分娩季節의 效果에 관한 調査

文点東,金哲旭 진주산업대학교 1984 論文集 Vol.22 No.-

Putting all accounts together obtained in this survey, mating type, parity and farrowing season have a high effect on reproduction traits before weaning of swine. Among mating types surveyed, the reproduction traits of 3­breedcrosses were superior to those of purebred and 2­breed crosses. Parity effects were important for the traits and the reproduction traits were superior in the 2nd to 5th parity to the other parity. Spring and fall­farrowed pigs and litters tended to be superior. The magnitude and direction of the farrowing season effects changed across the years resulting in significant year season interactions. Therefore, I think that breeding plans to improve effectively the reproduction traits before weaning are to be utilize the crossbred having highly the effect of heterosis and be farrowed in spring and fall.

소규모사업장 용접근로자들의 소음·용접흄·망간 노출에 관한 연구

김동구,문덕환,이채관,박명희,함성애,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

Objective : This study was conducted for the purpose of investigating the level exposure of welders to noise, welding fume and Manganese(Mn) related to this process. Methods and Material : All subjects in this study were welders engaged in CO2 arc and coated arc welding process especially in small-scale enterprises classified by type of manufacture of ship building, repairing and of other fabricated metal products, which is located in Gimhae and Milyang of Kyeongsang province in south Korea. Air sampling of welding fume was measured, shipped and analyzed on the basis of national institute for occupational safety and health(NIOSH) method in U.S. and work environment measurement method established in south Korea. To measure Noise in the work environment, Noise dosimeter was used on the basis of work environment measurement method established in south Korea. Result : This study was performed during a period from January, 2000 to December, 2001 and Results were as follows: 1. Noise level measured in this work environment was higher than national criteria for permissible exposure limit on health examinations related to hearing loss. 2. The concentration of welding fume and Mn in manufacture of ship building and repairing was higher than those in manufacture of other fabricated metal products. 3. In conditions of existing in ventilation system installed and operated, the concentration of welding fume and Mn was slightly lower than those of not existing. 4. In conditions of existing in sufficient air supply from out door into the work place relied on natural exhaust system, the concentration of welding fume and Mn was slightly lower than those of in not sufficient. 5. In all subjects, a rate of wearing ear plug and respiratory mask for dust and fume was lower than that of not wearing. Conclusion : According to above results, this study suggests that more positive work environment managements such as the use of portable local ventilation system, the supply of highly qualified personal protective equipment, and consecutive education and training related to health protection should be need to acquire suitable health protection program for welders engaged in small-scale enterprises in Korea.

제주화산회토양에 있어서 목초의 인산이용에 관한 연구 : 1. 농암갈색 화산회토양에 있어서 목초류의 인산시료 이용

김문철,정창조,김동암 제주대학교 농과대학 제주도축산문제연구소 1988 畜産論叢 Vol.3 No.1