Ethanol fermentation by wild mushroom cultures isolated from Korea

Do Bin Shin,Trung Kien Nguyen,Kyung Rim Lee,Mi Ja Shim,Min Woong Lee,Kyung Hoan Im,Tae Soo Lee 한국버섯학회 2013 버섯 Vol.17 No.2

Xylose Fermentation for Ethanol by Mushrooms isolated from Korea

Do Bin Shin,Trung Kien Nguyen,Kyung Rim Lee,Mi Ja Shim,Min Woong Lee,Kyung Hoan Im,Tae Soo Lee 한국버섯학회 2013 버섯 Vol.17 No.2

대학 내 블랜디드 러닝 이용자의 자기결정성 요인이 학습흥미와 즐거움을 통해 만족도에 미치는 영향

신유빈(Yu Bin Shin),이도윤(Do Yun Lee),권두순(Do Soon Kwon),박동철(Dong Cheul Park) 학습자중심교과교육학회 2022 학습자중심교과교육연구 Vol.22 No.15

목적 본 연구의 목적은 대학 내 학생들을 대상으로 블랜디드 러닝 이용자의 지각된 자율성, 유능성, 관계성을 파악한 뒤 학습흥미와 즐거움를 통해 그에 대한 만족도를 연구하고자 한다. 이를 통해 블랜디드 러닝을 통해 학습자에 미치는 영향과 블랜디드 러닝의 발전방안에 대해 제시하고자 한다. 방법 설문조사는 블랜디드 러닝을 이용 경험이 있는 서울 소재 S대학, 지방 K대학을 대상으로 실시했으며, 온⋅오프라인 설문을 배포, 회수하였다. 설문조사 기간은 2022년 02월 01일부터 2022년 02월 15일까지 2주간 실시되었다. 이 기간에 총 229부의 설문이 회수되었고, 229부의 설문지가 자료 분석에 사용되었다. 결과 첫째, 블랜디드 러닝의 지각된 자율성은 학습흥미와 즐거움에 유의미한 영향을 미치는 것으로 나타났다. 둘째, 블랜디드 러닝의 지각된 유능성은 학습흥미와 즐거움에 유의미한 영향을 미치는 것으로 나타났다. 셋째, 블랜디드 러닝의 지각된 관계성은 학습흥미와 즐거움에 유의미한 영향을 미치는 것으로 나타났다. 넷째, 블랜디드 러닝의 학습흥미는 즐거움과 만족도에 유의미한 영향을 미치는 것으로 나타났다. 다섯째, 블랜디드 러닝의 즐거움은 만족도에 유의미한 영향을 미치는 것으로 나타났다. 결론 본 연구의 결론은 다음과 같다. 지난 몇 년간 계속 지속되고 있는 코로나 펜데믹로 인해 대학 내 교수자는 블랜디드 러닝을 통해 수업에 대처할 수 있는 능력을 키우는 동시에 학습자에게도 수업 환경의 변화로 인한 능동적인 대처 능력을 키웠을 것이라 예상한다. 그렇지만 대학 내 블랜디드 러닝을 통해 학습이 진행될 때 학습자의 자기결정성이 중요하다는 것이다. 학습자를 대상으로 블랜디드 러닝에 대한 학습만족도를 높이기 위해서는 교수자는 학습자의 자기결정성을 갖도록 해야 할 것이다. Objectives The purpose of this study is to investigate the perceived autonomy, competence, and relationship of blended learning users among university students, and then to study their satisfaction through learning interest and pleasure. Through this, I would like to present the impact on learners through blended learning and the development plan of blended learning. Methods The survey was conducted for S-University in Seoul and local K-University with experience in using blended learning, and online and offline questionnaires were distributed and collected. The survey period was conducted for two weeks from February 01, 2022 to February 15, 2022. A total of 229 questionnaires were collected during this period, and 229 questionnaires were used for data analysis. Results First, the perceived autonomy of blended learning was found to have a significant effect on learning interest and enjoyment. Second, the perceived competence of blended learning was found to have a significant effect on learning interest and enjoyment. Third, the perceived relationship of blended learning was found to have a significant effect on learning interest and enjoyment. Fourth, learning interest in blended learning was found to have a significant effect on pleasure and satisfaction. Fifth, the pleasure of blended learning was found to have a significant effect on satisfaction. Conclusions The conclusion of this study is as follows. Due to the coronavirus pandemic that has continued over the past few years, it is expected that professors at universities will develop their ability to cope with classes through blended learning, while also increasing learners' ability to actively cope with changes in the class environment. However, the self-determination of the learner is important when learning proceeds through blended learning in universities. In order to increase the learning satisfaction of blended learning for learners, the instructor should have learners' self-determination.

Acetylcholinesterase, inflammation, and diabetic inhibitory activities of Lentinus giganteus

Trung Kien Nguyen,Do Bin Shin,Jae Hyuk Choi,Kyung Hoan Im,Min Woong Lee,Pyung Gyun Shin,Tae Soo Lee 한국버섯학회 2014 버섯 Vol.18 No.1

Lentinus giganteus is a edible mushroom cultivated in Asian countries. The present study was initiated to evaluate the anti-inflammatory, anti-acetylcholinesterase, anti-α-glucosidase, and free radical scavenging activities from fruiting bodies of L. giganteus extracted with methanol and hot water. The free radical scavenging activities of methanol and hot water extracts on 1,1-diphenyl-2-picrylhydrazyl (DPPH) were 92.26% and 90.17% at 2.0 mg/mL concentration, respectively and comparable with positive control, BHT. The chelating activities of methanol and hot water extracts were significantly higher than the positive control tested. The reducing power of methanol and hot water extracts showed lower activities compared to positive control, BHT. The phenolic and flavonoid contents of hot water extract were 1.56 μg/mg and 24.35 μg/mg, respectively. Nitric oxide (NO) produced by lipopolysaccahride (LPS) activated RAW 264.7 cells were significantly inhibited by treatment of methanol and hot water extracts. The methanol extract inhibited the acetylcholinesterase (AChE) activity by 91.19% at the 2.0 mg/mL concentration, whereas galanthamine, the standard drug, inhibited the AChE activity by 97.80%. The hot water extracts inhibited the α-amylase and α-glucosidase activities by 78.86% and 80.78%, respectively at the 2.0 mg/mL concentration, while acarbose, the positive control, inhibited the activities by 89.91% and 81.81%, respectively at the same concentration. Therefore, it is concluded that fruiting bodies of L. giganteus contain antioxidant, anti-inflammatory, anti-cholinesterase, and anti-diabetic substances, which can be used for natural health food for promoting human health.

Free Radical Scavenging, Anti-cholinesterase, Anti-inflammation, and α-Glucosidase Inhibitory Effects of Russula compacta Fruiting bodies

Trung Kien Nguyen,Do Bin Shin,Jae Hyuk Choi,Kyung Hoan Im,Mi Ja Shim,Min Woong Lee,Tae Soo Lee 한국버섯학회 2014 버섯 Vol.18 No.1

Russula compacta, a wild mushroom, belongs to Russulaceae, Russulales of Basidiomycota. This study was conducted to evaluate the free radical scavenging, anti-inflammatory, anticholinesterase and anti-α-glucosidase effects from fruiting bodies of R. compacta extracted with methanol and hot water. In 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging effects, the methanol and hot water extracts showed good scavenging effects comparable with positive control, BHT. The chelating effect of methanol and hot water extracts of the mushroom were significantly higher than the positive control, BHT. The reducing power of the methanol and hot water extracts of the mushroom were lower than the positive control at the concentrations tested. In the HPLC anaysis of phenolic acids profile of the mushroom extract, 7 phenolic acids such as gallic acid, vanillin, rutin hydrate, resveratol, quercetin formononetin, and biochanin-A were detected. Nitric oxide (NO) production in lipopolysaccahride (LPS) activated RAW 264.7 cells was inhibited by 1.5-fold with the treatment of methanol extract when compared with the control. In the anti-cholinesterase activity assay, the methanol extract inhibited the acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) effects by 73.9% and 81.05% at the 1.0 mg/mL concentration, whereas galanthamine, the standard drug, inhibited the AChE and BChE activities by 97.80% and 81.12%, respectively at the same concentration. The methanol and hot water extracts of the mushroom inhibited the α-glucosidase activity by 55.44% and 62.00%, respectively at the 2.0 mg/mL concentration, while acarbose, the positive control inhibited the α-glucosidase activity by 81.81% at the 2.0 mg/mL concentration. From the experimental results, the fruiting bodies of R. compacta contained natural antioxidant, anti-inflammatory, anti-cholinesterase, and anti-diabetic substances, which might be used for health foods.

Free radical scavenging, Anti-acetylcholinesterase, Anti-inflammatory, and α-Glucosidase Inhibitory Activities of Coprinellus micaceus

Trung Kien Nguyen,Do Bin Shin,Jae Hyuk Choi,Kyung Hoan Im,Min Woong Lee,Tae Soo Lee 한국버섯학회 2014 버섯 Vol.18 No.1

Coprinellus miaceus, belongs to Coprinaceae of Agaricales, Basidiomycota, has been used for an edible purposes in asian countries. This experiment was initiated to evaluate the free radical scavenging, free radical scavenging, anti-acetylcholinesterase, anti-inflammatory and α-glucosidase inhibitory activities of C. micaceus fruiting bodies extracted with methanol and hot water. In 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay, the scavenging activities of methanol and hot water extracts were lower than that of positive control, BHT. The chelating effects of methanol and hot water extracts were significantly higher than positive control, BHT at the concentrations of 0.125-2.0 mg/mL. In the reducing power assay, methanol and hot water extracts exhibited the lower activities than the positive control, BHT at the 0.125-0.2 mg/mL concentration. In the HPLC analysis of phenolic acids profile of the mushroom fruiting bodies, 4 phenolic compounds including procatechuic acid, chlorogenic acid, (-)-epicatechin, and naringin were detected. The tyrosinase inhibitory activities of methanol and hot water extracts were 91.33% and 91.99% at 2.0 mg/mL concentration, while the inhibitory activity of kojic acid, the positive control, was 99.61%. Nitric oxide (NO) production in lipopolysaccahride (LPS) activated RAW 264.7 cells were inhibited by the methanol extract in a concentration dependent manner. In the acetylcholinesterase (AChE) inhibitory activity assay, methanol and hot water extracts of the mushroom inhibited the AChE by 94.64% and 74.19%, respectively at the 1.0 mg/mL concentration, whereas galanthamine, the standard drug inhibited the AChE activity by 97.80% at the same concentration. The methanol and hot water extracts of the mushroom inhibited the α-glucosidase activity by 62.26% and 67.59%, respectively at the 2.0 mg/mL concentration, while acarbose, the positive control inhibited the α-glucosidase activity by 81.81% at the same concentration. Therefore, it is concluded that fruiting bodies of C. micaceus contained natural antioxidant, anti-inflammatory, anti-acetylcholinesterase and α-glucosidase inhibitory substances which might be used for promoting human health.

Storage Benchmarking System using NoSQL Database Engines

Do-Jin Choi,Song-Hee Park,Soo-bin Park,Yeon-Hee Baek,Bo-Kyoung Shin,So-Min Lee,Jae-Yong Choi,Jae-Yeol Park,Jong-Tae Lim,Kyoung-Soo Bok,Jae-Soo Yoo 한국콘텐츠학회 2019 한국콘텐츠학회 ICCC 논문집 Vol.2019 No.12

Patient outcomes and prognostic factors associated with colonic perforation surgery: a retrospective study

Do-bin Lee,Seonhui Shin,양춘석 영남대학교 의과대학 2022 Yeungnam University Journal of Medicine Vol.39 No.2

Background: Despite advances in surgery and intensive perioperative care, fecal peritonitis secondary to colonic perforation is associated with high rates of morbidity and mortality. This study was performed to review the outcomes of patients who underwent colonic perforation surgery and to evaluate the prognostic factors associated with mortality. Methods: A retrospective analysis was performed on 224 consecutive patients who underwent emergency colonic perforation surgery between January 2008 and May 2019. We divided the patients into survivor and non-survivor groups and compared their surgical outcomes. Results: The most common cause of colon perforation was malignancy in 54 patients (24.1%), followed by iatrogenic perforation in 41 (18.3%), stercoral perforation in 39 (17.4%), and diverticulitis in 37 (16.5%). The sigmoid colon (n=124, 55.4%) was the most common location of perforation, followed by the ascending colon, rectum, and cecum. Forty-five patients (20.1%) died within 1 month after surgery. Comparing the 179 survivors with the 45 non-survivors, the patient characteristics associated with mortality were advanced age, low systolic blood pressure, tachycardia, organ failure, high C-reactive protein, high creatinine, prolonged prothrombin time, and high lactate level. The presence of free or feculent fluid, diffuse peritonitis, and right-sided perforation were associated with mortality. In multivariate analysis, advanced age, organ failure, right-sided perforation, and diffuse peritonitis independently predicted mortality within 1 month after surgery. Conclusion: Age and organ failure were prognostic factors for mortality associated with colon perforation. Furthermore, right-sided perforation and diffuse peritonitis demonstrated a significant association with patient mortality.

Increasing Incidence of Inflammatory Bowel Disease Among Young Men in Korea Between 2003 and 2008

Shin, Dong Hyuk,Sinn, Dong Hyun,Kim, Young-Ho,Kim, Jin Yong,Chang, Dong Kyung,Kim, Eun Jin,Ryu, Ho Yoel,Song, Han Ul,Kim, Il Young,Kim, Do Hyoung,Kim, Yun Young,Kim, Suk Hun,Seo, Yu Bin,Hwang, Ki Won Springer-Verlag 2011 Digestive diseases and sciences Vol.56 No.4

A survey of knowledge and practices regarding atopic dermatitis

( Young Bin Shin ),( Jeong Won Jo ),( Hae Bong Jeong ),( Yun Sun Moon ),( Do Seon Jeong ),( Sang Min Lee ),( Eui Chang Jung ),( Chi Yeon Kim ),( Tae Jin Yoon ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.2

Background: The recognition of basic skin care practice education has been increased. Recently, there was a report that participants most often received education on skin health from their clinics and take care their baby more effectively. Objectives: In this study, we survey on knowledge resources and behavior regarding atopic dermatitis. Methods: A questionnaire consisting of 28 questions concerning demographics and use, knowledge, and educational program participation was checked from patients and accompanying persons who visited dermatologic clinics. Results: The most patients replay (96%, 86/90) and want to know the prognostic factor of atopic dermatitis(97.8%), proper ointment usage(96.8%), effective basic skin care practice(93.3%) and what to look for during the ordinary life(91.1%). The results show the most of patients want to learn about knowledge and practices regarding proper medical/non-medical skin care make their skin more comfortable. Conclusion: The result shows dermatologist should provide the proper information to their patients and an action that can help their patients to take care of themselves.