전자선과 불가사리 분말을 이용한 하수슬러지 탈수능 향상

유대현,이재광,이면주 한국환경과학회 2004 한국환경과학회지 Vol.13 No.7

This study was focused on the manufacturing method of a dewatering aid, which would reduce the water content of the sludge cake by enhancing the dewaterability of sewage sludge. The pretreatment technology for sludge by using radiation and among diverse discarded resources were starfish selected as the material to manufacture the dewatering aid. Starfish went through the process of washing, drying, and pulverizing. The starfish powder made in this process was applied to the digested sludge generated at the sewage treatment plant of D City, and its effects were investigated. The starfish powder that was 300 ㎛ in particle size was added to the irradiated digested sludge. After the application of the condensation process, the sludge with the starfish powder added was dewatered using the belt press and centrifuge, which were the traditional pressure dewatering devices. As the result, it reduced the water content of the sludge 20% higher than the dewatered cake with no dewatering aid added and irradiation. When the powder was added, it contributed to less use of the coagulant added. The more irradiation dose, the lower water content did the dewatered cake have and the more coagulant was needed for condensation, which seems to be a disadvantage that can be compensated for by the starfish dewatering aid. A small-scaled treatment of the study to a radiation technology and dewatering aid using a discarded resource confirmed the potential of dewaterability. Based on the results saying that the dewatering aid and radiation technology can improve dewatering effects using the traditional dewatering devices, this pretreatment technology will be expected to be applied to sewage treatment plants.

류마티스 관절염의 진단과 치료

유대현 한양대학교 의과대학 1998 한양의대 학술지 Vol.18 No.1

Rheumatoid arthritis(RA) is an autoimmune disorder of unknown etiology characterized by symmetric, erosive synovitis and sometimes multisystem involvement. Most patients exhibit a chronic fluctuating course of disease that, if left untreated, results in progressive joint destruction, deformity, disability, and premature death. Optimal management of requires early diagnosis and timely introduction of agents that reduce the probability of irreversible joint damage. The development of immunology and biotechnology have changed the management of RA: a strategy based on long-term treatment with nonsteroidal anti-inflammatory drugs and the addition of second line agents only in a later phase of disease (pyramid theraphy) has evolved to a more aggressive approach with the early intorduction of second line drugs in most patients with RA. Here I would like to review briefly advances of pathogenic mechanisms and current trend of RA treatment.

고등학교 영재 학생들이 선호하는 수학 수업형태와 수업환경

이대원,고호경,유미현 韓國英才學會 2012 영재교육연구 Vol.22 No.1

본 연구의 목적은 고등학교 영재 학생이 선호하는 수학 수업형태와 수업환경에 대한 인식을 조사함으로써 영재 학생들의 수업 만족도를 높이고 효과적인 영재 수업전략을 구상하는 것이다. 본 연구의 결과는 다음과 같다. 첫째, 영재 학생과 일반 학생의 수학 수업형태 하위 영역 중 다양화와 특성화는 영재 학생의 선호도가 높았고, 명료화는 일반 학생이 선호도가 유의미하게 높은 것으로 나타났다(p<.05). 둘째, 영재 학생 및 일반 학생의 성별에 따른 수학 수업형태와 수업환경 선호도에서는 전체적으로 여학생의 평균점과 선호도가 높았으나, 통계적으로 유의미한 차이는 심리 영역에서만 나타났다. 셋째, 영재 학생들은 수업방법, 교실과 교사태도 영역에서 영재 학급과 일반 학급에서 유의미한 선호 차이가 나타났다(p<.05). The purpose of this study is to design a more satisfactory and efficient teaching strategy for the gifted by comparing teaching type and learning environment preferred by the gifted with that preferred by normal students. As a result, the following findings are obtained. First, while the normal class students show higher preference for clarification and organization, gifted students prefer for diversification and specialization. Second, with the respect to the gender-related forms of mathematics classroom environment, the overall female preference and the average score are higher, indicating significant difference in the area is only a psychological domain. Third, compared to the regular classroom, the gifted have significantly different preference for teaching method, classroom and teachers' attitude between in the gifted class and regular class.

척추관절염의 최신 치료 경향

유대현 대한의사협회 2003 대한의사협회지 Vol.46 No.11

자동 경계 탐지(Automated Border Detection)심초음파도를 이용한 좌심방 면적 및 기능의 평가

김현주,주승재,임진형,정효균,이영수,유호대,차태준,이재우 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.2

간호대학생의 MBTI 성격유형과 학습태도, 학업성취도간의 상관성

정현경,김명수,유연자,김수옥,원대영 대한간호행정학회 2007 간호행정학회지 Vol.13 No.4

Purpose: This study was to explore the relationship between personality type and learning attitude and academic achievement of nursing students. Method: 91 students were sampled from freshman in nursing school. Data were collected from April 2 to October 5 2007. Analysis of the results were carried out using SPSS win 12.0 for frequency, mean and standard deviation, t-test, ANOVA, Pearson correlation. Result: The result of MBTI test was that nursing students in this study showed extraversion(52.7%), sensing(82.4%), thinking(56.0%), judging(57.1%). Academic achievement according to personality was that only feeling(F) type students had significantly higher score of English than thinking(T) type students(p=.013). Learning attitudes according to personality were that sensing(S) type students had significantly positive attitude toward their college than intuition(N) type students (p=.016). And think(T) type students had significantly higher confidence of learning than feeling(F) type students. There was significant positive correlations between learning method and score of English, Fundamental Nursing, Anatomy(p<05). Conclusions: Diagnosing personality can differentiate student's learning attitude. It is important to develop teaching-learning strategies according to their personality, which can help them to improve their academic achievement.

상황버섯(Phellinus linteus)으로부터 Ergosterol의 분리

류하나,유종수,송명종,이대영,김동현,노영덕,김인호,백남인 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1

상황버섯을 80% MeOH 용액으로 추출하고, 추출물을 EtOAc, n-BuOH 및 물로 분배, 추출하였다. 이 중 EtOAc 분획을 silica gel 및 octadecylsilica gel(ODS) column chromatography로 정제하여 1종의 sterol 화합물을 분리하였다. 화합물의 화학구조는 NMR, MS 및 IR 등의 스펙트럼 데이터를 해석하여, ergosta-7,22E-diene-3β,5α,6β-triol(cerevisterol, 1)로 동정하였다. 이 화합물은 상황버섯에서 처음 분리 보고 되었다. Phellinus linteus was extracted with 80% aqueous MeOH, and the concentrated extract was partitioned with EtOAc, n-BuOH and H_(2)O. The repeated silica gel and ODS column chromatographies of the EtOAc fraction led to the isolation of one sterol. From the result of spectral data including NMR, MS and IR, the chemical structure of the sterol was determined as ergosta-7,22E-diene-3β,5α,6β-triol (cerevisterol, 1). Compound 1 was isolated from the Phellinus linteus for the first time in this study.

만성 심부전 환자에서의 Denopamine 투여효과

최석구,김현대,정태기,김대현,김용복,유원상 인제대학교 1994 仁濟醫學 Vol.15 No.2

만성 심부전 환자에게 새로운 경구용 비 digitalis 강심제인 denopamine 1T(5mg)을 1일 3회 3개월간 투여하여 그 유효성 및 안전성을 검토했다. Background : Patients with congestive heart failure have a high mortality rate and are also hospitalized frequently. We studied the effects of a new oral inotrophic agent, denopamine in patients with chronic heart failure. Methods : 16 patients receiving conventional treatments for heart failure were treat ed with denopamine 5mg tad for at shortest 3 months. Their history were taken and the physical examination, general laboratory test and the echocardiographic examination were done before and after treatment. Results: There were 3 deaths and 1 withdrawal because of worsening heart failure. 5 patients (42%) among 12 patients showed the improvement in their subjective symptoms. The fractional shortening and ejection fraction of the left ventricle were increased by 3.2% and 5.6% respectively in their absolute values. Conclusion : The addition of denopamine to conventional therapy considerably improved the subjective symptoms and the left ventricular function in the limited number of patients with chronic heart failure.

H9c2 심근 세포주에서 외인성 nitric oxide가 허혈에 의한 세포 독성에 미치는 영향

정성구,장현용,김명천,고영관,정주호,배영미,박원서,김대중,유영민,김성수,임성빈 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Background: Nitric oxide(NO) is known to have protective effects on an ischemic heart and to exert triggering effects on ischemic preconditioning. However, the effects of NO during the ischemic period have not been investigated. To investigate the role of exogenous nitric oxide in a model of ischemic heart cell death, we studied the effects of ischemic preconditioning and ischemia in a normal and an ischemic buffer. Methods: Rat cardiac myoblast cells(H9c2) were cultured in a normal and an ischemic buffered medium. For the ischemic culture of heart cells, the cells were cultured in a dessicator with GasPak for 5 hrs. In ischemic preconditioning, the cells were pretreated with ischemic buffer for 5 min and then perfused with normal medium for 30 min. For the measurement of the cytotoxicity, a MTT(3-4-Sdimethylthiazol-2-yl-2,5-diphenyl tetrazolium bromide) assay was performed. A DAPI(4',6-diamidino-2-phenylindole dihydrochloride) staining procedure and a flow cytometry analysis were performed to confirm apoptotic cell death by ischemia. Results: Cell viability, as determined by using a MTT assay, showed that the preconditioned group treated with NO showed more cell death than with the not-preconditioned groups in both normal and ischemic buffers. But, In normal medium and not-preconditioned groups, NO showed protective effect according to the concentrations(100,1000μM) . No treatment with NO produced the different results. In normal medium, the protective effect of ischemic preconditioning was demonstrated, but no protective effect of ischemic preconditioning could be seen in the case of the ischemic buffer. The DAPI staining and flow cytometry analysis of heart cells showed characteristic apoptotic features. Conclusion: NO added in the ischemic phase had deterious effects on heart cells. Ischemic preconditioning was more harmful than ischemia alone. The toxicity of the cells was characteristic apoptosis.

위 MALT 림프종에서 다발성 림프절 전이로 오인된 동시성 림프절 결핵 1예

김성은,김규종,김도현,송준영,문대성,장리라,유찬희,문원,박무인,박선자,김영옥 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.2

28세 남자가 내시경적 점막절제술을 통해 저등급 위MALT 림프종으로 진단되었다. 병기설정을 위해 18F-FDG PET 검사를 시행하였고 우측 쇄골상부, 우측상/하부 기관주위, AP window 부위에 강한 섭취가 관찰되어 전이성 림프절로 판단하였다. 그러나, 우측 쇄골상부 림프절에서 시행한 절제생검에서 만성육아종성염증소견이 관찰되었고 조직의 결핵 중합효소연쇄반응에서도 양성 반응을 보였다. 2개월간 항결핵제의 사용 후 시행한 추적 컴퓨터단층촬영 검사에서 림프절 크기의 감소를 보여 최종적으로 위 MALT 림프종에서 광범위 림프절 전이로 오인된 동시성 림프절 결핵으로 진단되었다. A 28-year-old man was diagnosed as gastric MALT lymphoma in diagnostic EMR (endoscopic mucosal resection). He subsequently underwent an 18F-FDG PET. 18F-FDG PET showed intense multifocal uptake in right supraclavicular, right upper and lower paratracheal, and AP window areas that was considered radiologically to represent widespread metastatic lymphadenopathy. Excisional biopsy of a supraclavicular lymph node, however, revealed chronic granulomatous lymphadenitis with a positive reaction of Tb-nested PCR. After antituberculosis treatment for 2 months, a follow-up CT scan showed complete resolution of the lesions. Intense 18F-FDG uptake could be due to an infectious process such as synchronous tuberculous lymphadenitis. Therefore, this could mimic a malignant condition such as lymphoma with extensive lymph node metastasis due to a false-positive finding, which may lead to a misdiagnosis.