데이터 글러브를 이용한 손 제스처 기반 3차원 게임 구현

유다연,권차욱,곽지민,백화현,김이조,차경애 대구대학교 정보통신연구소 2010 情報通信硏究 Vol.7 No.1

데이터 글러브(Data Glove)는 손 제스처를 정의하여 시스템을 제어하는 입력장치로 가상현실기술 및 교육, 의료, 산업분야에서 많이 사용되고 있다. 이는 가상현실 속에 존재하는 사물을 현실에서 제어하게 함으로써 사용자에게 마치 현실 세계의 사물을 제어하는 느낌을 주는 장점을 가지고 있다. 이에 본 논문에서는 이러한 데이터 글러브의 장점을 이용하여 3차원 게임에 적용시키는 방법을 제안한다. 먼저 데이터 글러브로 제스처를 정의하고, 트래커(Tracker)와 연동하여 시스템을 구현한다. 구현된 시스템을 실험하기 위해서 OpenGL로 인형 뽑기 게임을 구현하고 사용자가 데이터 글러브를 착용 후 정의된 제스처를 통해 게임을 제어하도록 한다. 본 논문에서 제안한 방법은 사용자들에게 좀 더 높은 몰입감을 제공하며, 향후 게임 산업 발전에도 많은 영향을 줄 것으로 기대한다.

Pediatric tuberous xanthoma as a feature of familial hypercholesterolemia: a case report

( Da-ae Yu ),( Ohsang Kwon ),( Kyu Han Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Familial hypercholesterolemia, also known as type IIa hyperlipoproteinemia, is a lipid metabolism disorder characterized by high level of low-density lipoprotein (LDL), xanthomas, and early onset of cardiovascular diseases. Tuberous xanthomas are non-tender, yellow, subcutaneous nodules that usually involve the extensor of limbs and buttock in patients with familial hypercholesterolemia. A 10-year-old boy presented multiple asymptomatic yellow nodules and papules on the left elbow and right knee for 2 years. The patient had no underlying disease but had family history of acute myocardial infarction of his father. His mother was previously diagnosed with gestational diabetes mellitus and hypercholesterolemia, and his fraternal twin had mental retardation. Routine laboratory results were normal, but serum lipid profile showed markedly increased level of total cholesterol (421 mg/dl) and LDL (351 mg/dl). Lipoprotein electrophoresis revealed the increase of the beta-fraction (73.7%). No mutation was detected in coding region of LDL receptor (LDLR) gene. Based on the clinical features and laboratory results, the patient was subsequently diagnosed as tuberous xanthoma with familial hypercholesterolemia. After starting atorvastatin daily, the serum lipid profiles showed improvement in 4 months. This is a case of tuberous xanthomas that developed early in childhood as the first manifestation of familial hypercholesterolemia.

Efficacy of topical agents in lichen striatus: a comparative study

( Da-ae Yu ),( Jungyoon Ohn ),( Ohsang Kwon ),( Kyu Han Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Lichen striatus is a self-limited linear inflammatory dermatosis, and topical corticosteroid or calcineurin inhibitors have been reported to be effective. Objectives: To compare the efficacy of topical agents in lichen striatus. Methods: We retrospectively reviewed medical records and clinical photos of 60 pediatric patients with lichen striatus at Seoul National University Hospital from March 2007 to December 2017. The patients were classified into three groups by topical agent; calcipotriol, calcineurin inhibitor, and corticosteroid, and follow-up duration and treatment outcome were analyzed. Results: Among a total of sixty pediatric patients, twenty seven patients (45.0%) were male. Most common anatomical locations were lower extremities (51.7%) and upper extremities (33.3%). Mean age at first visit was 3.8 years, and mean follow-up duration was 192.6 days. Good response (>75% improvement) to treatment was observed in twenty two of forty patients treated with calcipotriol (55.0%), six of thirteen patients with corticosteroid (46.2%), and three of seven treated with calcineurin inhibitor (42.9%), and there was no statistical significance. No significant adverse events were observed in all groups. Conclusion: Though there was no statistically significant difference in treatment efficacy among the topical treatment groups, topical calcipotriol showed a tendency to shorten the course of the disease. Topical calcipotriol may be a safe and effective topical agent for lichen striatus.

Adverse pregnancy outcomes in female patients with alopecia areata: a nationwide population-based study in Korea

( Da-ae Yu ),( Soo Ick Cho ),( Ohsang Kwon ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

Background: Alopecia areata (AA) is a common hair loss disorder that is characterized by autoimmune attack against the hair follicles. Several autoimmune disorders are associated with adverse pregnancy outcomes, but the effects of AA on pregnancy outcomes are not yet discovered. Objectives: To investigate the pregnancy outcomes in female patients with AA Methods: We performed a nationwide, population-based retrospective case-control study using the Korean National Health Insurance claims database from 2011 to 2017. The pregnancy outcomes of 4,552 female patients with AA and 508,345 control subjects were analyzed using multivariate logistic regression models, adjusted by age, comorbidities (autoimmune diseases and metabolic disorders), and obstetric and gynecological diseases. Results: AA patient group showed high frequency of autoimmune diseases and pelvic inflammatory disease, compared to control group. They showed a lower total live birth rate (odds ratio (OR), 0.876; 95% confidence interval (CI), 0.820-0.937) and higher rates of all kinds of abortion (OR, 1.145; 95% CI, 1.071-1.225) and ectopic pregnancy (OR, 1.261; 95% CI, 1.112-1.431) after adjustment. Conclusion: AA is associated with an increased risk of abortion, especially ectopic pregnancy. This study may contribute both to the understanding of obstetric comorbidities in AA and to the better management for pregnancy.

Effect of topical timolol 0.5% solution on infantile hemangiomas: a retrospective study of 353 cases

( Da-ae Yu ),( Jong Seo Park ),( Hanjae Lee ),( Jungyoon Ohn ),( Ohsang Kwon ),( Kyu Han Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.2

Background: Topical timolol has been reported as an efficient and safe topical agent for superficial infantile hemangiomas (IHs). However, there are limited data about the outcome and several factors affecting the treatment response to topical timolol. Objectives: To investigate the efficacy, safety, and the predictive values for good response of topical timolol for IHs. Methods: We retrospectively reviewed medical records and clinical photos of IH patients treated with topical timolol at Seoul National University Hospital from June 2011 to December 2017. To evaluate the response to treatment, serial clinical photographs were compared to that of initial visit using a 100mm visual analog scale (VAS). Results: A total of 353 IH patients were treated with topical timolol. Mean age at initiation of treatment was 4.71±5.33 months, and 254 patients (72.0%) started treatment before the age of six months. Final VAS was significantly low in the deep or mixed type (P = .003), in flexural area (P = .006), and in the patients with treatment initiation after 12 months of age (P = .001). Also, IH patients with preterm or SGA history showed significantly lower initial VAS at 1- and 2-month from baseline (P = .004, P = .005, respectively). Mild adverse events were reported in four patients with local irritation. Conclusion: Topical timolol was safe and effective treament for IHs, and the superficial type, non-flexural location, and early initiation of treatment may be good responders to topical timolol.

Hypomelanosis of Ito with multiple congenital anomalies

( Da-ae Yu ),( Ohsang Kwon ),( Kyu Han Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Hypomelanosis of Ito, also known as incontinentia pigmenti achromians, is a neurocutaneous disorder that is associated with chromosomal mosaicism in many cases. It is characterized by whorl-like or linear hypopigmentation along the Blaschko’s line in infancy, and other abnormalities involving the ocular, musculoskeletal, and central nervous system. A 2-month-old girl was referred to the department of dermatology for evaluation of the extending hypopigmented skin lesions developed at birth. She presented with symmetric, linear, hypopigmented patches with irregular border on the face, scalp, trunk, and both extremities. She had the history of intrauterine growth retardation as a prenatal problem. There was no specific family history and her two siblings were healthy. She also presented multiple congenital anomalies. Physical examination revealed patchy alopecia of scalp, hypoplastic nails, and irregular gingiva with saw tooth. Ocular examination showed bilateral microphthalmia, aniridia, and uncertain retinal vessels and optic nerves. Musculoskeletal examination showed syndactyly of toes, hypoplasia and clinodactly of fingers, and coccyx deviation. Chromosomal analysis showed normal karyotype, and NF-κB essential modulator (NEMO) IKBKG gene test for incontinentia pigmenti revealed no mutation. Herein, we report a rare case of hypomelanosis of Ito with multiple congenital anomalies in a patient without chromosomal mosaicism.

Lichen Striatus: Clinical Features and Treatment Outcomes of Topical Agent Use in 60 Pediatric Patients

( Da-ae Yu ),( Jungyoon Ohn ),( Ohsang Kwon ),( Kyu Han Kim ) 대한피부과학회 2020 大韓皮膚科學會誌 Vol.58 No.5

Background: Lichen striatus (LS) is a linear, inflammatory dermatosis that mainly affects children. To date, there are limited data comparing treatment outcomes between topical agents for pediatric LS. Objective: To investigate the clinical features and treatment outcomes associated with the use of topical agents for pediatric LS. Methods: We retrospectively reviewed the medical records and clinical photographs of 60 pediatric patients classified into three groups according to the topical agent used. Treatment response was evaluated by comparing subjective symptoms and clinical photographs obtained at each visit. Results: A good response (>75% clinical improvement from baseline) was achieved in 55%, 46.2%, and 42.9% of patients from the calcipotriol, corticosteroid, and calcineurin inhibitor groups, respectively. There were no statistically significant differences in treatment duration among groups. However, when compared to other drugs, calcipotriol showed a trend towards shortening the disease course duration. Conclusion: Topical use of calcipotriol, as well as corticosteroids and calcineurin inhibitors, may represent useful treatment options for pediatric LS, although further studies are required to confirm their efficacy and long-term safety. (Korean J Dermatol 2020;58(5):318∼323)

A case of acropustulosis of infancy treated successfully with topical corticosteroid and salicylic acid

( Da-ae Yu ),( Ohsang Kwon ),( Kyu Han Kim ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Acropustulosis of infancy is characterized by recurrent, self-limited, pruritic vesiculopustular eruptions on the distal extremities in early childhood. The cause is still unclear, but its association with the scabies infection is often reported. A 2-month-old male infant presented pruritic erythematous papules and pustules with crusts on the face, palms, soles, and scrotum for one month. Skin lesions first developed on the scrotum and then spread to the palms, soles and face. The patient had no underlying disease and there was no history of scabies in his family. Previous treatment with oral antibiotics and antihistamines could not improve his symptoms. According to the clinical manifestations, the patient was subsequently diagnosed with acropustulosis of infancy. Topical corticosteroid (desoxymethasone) ointment and salicyclic acid 5% ointment were applied on his hands and foots. After one week later, he came up with much improved state of the hand and foot lesions, but with remaining crusted lesions on the face. Then, topical corticosteroid (prednisolone valerate acetate) was also applied to the face lesions and almost all lesions disappeared after one month. Herein we report a case of acropustulosis of infancy that was treated successfully with topical treatment.

Blue rubber bleb nevus syndrome with facial nerve involvement: a case report

( Da-ae Yu ),( Chang-hun Huh ) 대한피부과학회 2018 대한피부과학회 학술발표대회집 Vol.70 No.1

Blue rubber bleb nevus syndrome is a rare disorder of venous malformation that affects the skin and internal viscera, such as gastrointestinal tract. Skin lesions usually appear as multiple dark blue nevi in the upper trunk and arm and may increase in size and number over lifetime. A 17 year old boy presented a bluish swelling on the left cheek since birth. Nasopharyngeal MRI showed diffused infiltrating hemangioma in the left masticator space and lower neck. Since he had no symptom other than swelling, no specific treatment was done. Twelve years later, he presented newly developed multiple bluish subcutaneous masses on his neck and anterior chest. Histopathological examination on the chest lesion showed multiple dilated vascular space lined by normal endothelium. Based on the clinical manifestations and histopathologic examination, the patient was subsequently diagnosed as blue rubber bleb nevus syndrome. He denied previous history of anemia or bleeding episodes, but had the history of objective hearing loss at regular check-up. Pure tone audiogram showed high-frequency hearing loss on the left ear. Temporal bone CT showed left facial nerve involvement of hemangioma. Esophagogastroduodenoscopy and colonoscopy revealed no vascular lesions. Herein we report a rare case of blue rubber bleb nevus syndrome with multiple skin lesions and unilateral hearing loss caused by facial nerve involvement.

Hypomelanosis of Ito with Multiple Congenital Anomalies

( Da-ae Yu ),( Ohsang Kwon ),( Kyu Han Kim ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.5

Hypomelanosis of Ito (HI) is a neurocutaneous disorder, also known as incontinentia pigmenti achromians. HI has been associated with chromosomal abnormalities, especially mosaicism. Herein, we report a case of HI with multiple congenital anomalies. A 2-month-old girl presented with multiple linear and whorling hypopigmentation on the face, trunk, and both extremities and patch alopecia on the scalp. Moreover, she had conical teeth, aniridia of the both eyes, and multiple musculoskeletal problems, including syndactyly and coccyx deviation. Cytogenetic analysis on peripheral blood was normal 46, XX, and no mutation was found in IKBKG gene test. (Ann Dermatol 31(5) 576∼580, 2019)