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        전기적 자극이 백서 대퇴골골단의 연골형서에 미치는 영향에 관한 연구

        고천석 大韓小兒齒科學會 1990 大韓小兒齒科學會誌 Vol.17 No.1

        The purpose of this study was to investigate the changes in the chondrogensis processes, induced by a direct electric current ranging 7-18㎂, of rat femur. 20 rats(Sprague-Dawley strain) weighing about 200gm were selected and divided into 2 groups, one control group consisting of 5 rats and one experimental group consisting of 15 rats. And the control and experimental group were subdivided into 5 groups according to the periods (6-hour, 12-hour, 1-day, 3-day, 7-day) that the electric stimulation applied. All surgery was performed under ether and thiopental sodium anesthesia with aseptic precautions, each naimal receibing 0.25cc/100gm of soluble ganamycin sulfate intraperitoneally at the end of the surgical procedure. A 0.010" stainless steel wire covered with posyethylene tube was tied at the right femoral neck portion of the rat, and this wire serving as a cathode was connected to the Constant Current Sink. Anode was implanted subcutaneously over the dorsum at the corss section area where the vertebral column and a line connecting the both iliac crests, and then connected to the Sink. Control groups were received the same electrodes but that those electrodes were not connected to the power supply pack. Animals were sacrified at 6-hor, 12-hour, 1-day, 3-day, and 7-day after the electrical stimulation. Head of femoral condyle was prepared for histologic findings including LM and EM. Based on the present study the following conclusions can be made. 1. It can be concluded that the activity of the chondroblasts was stimulated by means of direct electric current. 2. The increased activity of chondroblasts in the epiphyseal plate was noted at the 6-hour experimental group, and a marked increased activity was evident at 12-hor experimental group. 3. There appeared a secondary ossification center in the prechondroblastic layer at 3-day experimental group, and the epiphyseal plate of the 7-day experimental group showed an insignificant change relatively to the 7-day control rat. 4. The increased activity of the osteoclasts was marked at 24-hour experimental group, and the new bone formation was remarkable owing to the increased activity of the osteoblasts at 3-day experimental group. 5. The total energy dissipated approximately 0.13 joule elicited a marked changes of chondroblasts in the epiphyseal plate, and a remarkable bone formation was producd at about 0.33 joule.

      • 베타락탐계 항생제 합성과 항균성

        고옥현,강형룡,유진철,김경수,홍석순,김영수,황화영,하재천 조선대학교 약학연구소 1992 藥學硏究誌 Vol.14 No.1

        7β[5-(Substituted) phenyl-2H-tetrazol-2-yl]acetamidocephalospranic acid, 7β-(5-Diphnenyl-methyl-2H-tetrazol-2-yl) acetamidocephalosporanic acid and 7β-[5-(Substituted)-4-phenyl-1.2.4-triazol2-yl]thioacetamidocephalosporanic acid were synthesized and tested in vitro antimicrobial activity. These compounds exhibited good antimicrobial activity against Gram-positive bacteria whereas most compounds showed decreased antimicrobial activity against Gram-negative bacteria

      • KCI등재

        지렁이 분변토의 SO_2 가스 흡착특성

        金春姬,高京淑,安喆偶 한국환경과학회 2000 한국환경과학회지 Vol.9 No.2

        The purpose of this study was to determine whether Vermi Cast could be used effectively to remove SO_2 from flue gas, and then to investigate optimum adsorption conditions. The Vermi Cast used as adsorbent was mechanically screened with 8∼20 mesh sieve. The adsorption data for S0_2 were regressed using the Freundlich isotherm. The fit was generally satisfactory (R^2=0.945∼0.982). With the temperature changes from 20℃ to 40℃, the constant k in Freundlich isotherm q_e = kC_e^(1/n), decreased from 1.409 at 20℃ to 0.297 at 40℃, and the exponent 1/n were decreased from 0.343 to 0.134. With the bed depth changes from 10㎝ to 30㎝, the adsorption capacity expressed as m㏖ of SO_2 adsorbed per g of Vermi Cast increased from 0.247 to 0.381. Moisture content is an important parameter in the SO_2 adsorption efficiency. When the moisture content ranging 23∼53% temperature 28℃ the amount of SO_2 adsorbed were observed over 0.3m㏖ SO_2/g Vermi Cast. The best adsorption capacity was 0.487m㏖ SO_2/g Vermi Cast, and it was obtained with moisture content 37%, temperature 20℃. From the above results, it might be concluded that Vermi Cast is effectively available as a good adsorbent to remove SO_2 from flue gas.

      • 반건식-백필터에 의한 소각배가스 중의 HCI, SOx 제거 (Ⅰ)

        배병훈,신남철,고경숙,김춘희,문종익,임경택 동아대학교 환경문제연구소 1997 硏究報告 Vol.20 No.1

        This study has been carried out to investigate the removal efficiencies of HCl/SOx in a Spray-Dryer/Fabric-Filter system. In HCl/SOx removal, we could identify the key factors such as spray dryer outlet temperature, molar equivalence ratio(MER) and fabric filter velocity, but we couldn't find out the correlation of HCl and SOx. The removals of HCl/SOx were inversely proportional to spray dryer outlet temperature(l30~170℃) and filter velocity(l.0~1.5 m/min), at the MER, HCl removal efficiency was strongly proportional to MER, but SOx, removal efficiency was not particularly increased by MER over 1.5. The removal efficiencies of HCl/SOx were improved over 10% at the fabric filter. In this Spray-Dryer/Fabric-Filter system, HCl/SOx removal efficiencies were about 99%, 96% respectively.

      • VOCs의 光觸媒處理에 관한 硏究

        임경택,김춘희,고경숙,배병훈,문종익 동아대학교 환경문제연구소 1997 硏究報告 Vol.20 No.2

        This study has been carried out to observe photodegradation efficieny of TCE with the variation of IN irradiation strength, liquid thickness and immobilized TiO₂. The results are summarized as fallows; 1. Without photocatalyst, the TCE removal efficiency was observed to be about 15% with UV irradiation. 2. Above 93% of TCE were mineralized by immobilized TiO₂on glass panel(5g, 500℃) and UV irradiation. The photodegradation efficiency increased with increasing UV lamp numbers and reaction rate increased with increasing TCE initial concentration. 3. The photodegradation efficiency decreased with increasing the liquid thickness and above 96% of TCE were removed with using 3 UV lamps and liquid thickness less than 6cm.

      • 病院 地下空間內의 空氣中 微生物分布에 관한 硏究

        박천제,배병훈,고경숙,김춘희,임경택 동아대학교 환경문제연구소 1998 硏究報告 Vol.21 No.1

        This study was carried out to investigate the distribution and concentration of microorganism by the method of the air contamination using RCS air sampler in underground linac room of two general hospital located in Pusan. The places of air sampling were 4 different spot in two each hopital. Therefore, total 8 places were sampled from June 30, 1996 to May30, 1997. The results obtained were as follows 1. In a agar strip GK-A media for total count of microbial particles, it was estimated to be 76 CFU/ft^(3) in ICR room, and the consulting room was 53 CFU/ft^(3), lobby was XI CFU/ft^(3), linac room was 35 CFU/ft^(3), in the M hospital, respectively. The distribution of organism in the air of M hospital were shown gram positive cocci 72%, gram negative bacilli 15%, gram positive bacilli 6.1%, fungi 6.1%, respectively . On the other hand, in P hospital, it was obtained to be ICR room 74 CFU/ft^(3), lobby- 45 CFU/ft^(3), consulting room 34 CFU/ft^(3), linac room 31 CFU/ft^(3), respectively. The distribution and concentration of microorganism in the air were detected gram positive cocci 75%, fungi 10.3%, gram negative bacilli 8.7%, gram positive bacilli 6.0%. respectively. The results were recognized to be a low frequency in the linac room. 2. In agar strip S media for total counts of M hospital, ICR room was shown the highest organism with 32 CFU/ft^(3), but the lowest organism was detected linac room with 20 CFU/ft^(3). Also, the case of P hospital was estimated high 43 CFU/ft^(3) at ICR room, low organism was shown at linac 17 CFU/ft^(3) Test of coagulase were recognized to be a negative Staphylococci 68.3% in M hospital, 60.7% in P hospital. Coagulase positive cocci was estimated to be 31.7% in M hospital, 39.3% in P hospital. 3. In agar strip C media for coliform bacteria, colony counts at ICR room 10 CFU/ft^(3), consulting room 7 CFU/ft^(3), linac room 6 CFU/ft^(3), lobby 4 CFU/ft^(3) in M hospital, respectively. On the other hand, in P hospital were shown ICR room and main lobby 7 CFU/ft^(3), consulting room 5 CFU/ft^(3), linac room 4 CFU/ft^(3), respectively.

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