방광에서 발생한 염증성 근섬유아세포종

조시완,유지형,노충희,김정연,정재용,성락희 仁濟大學校 白病院 2010 仁濟醫學 Vol.31 No.-

Spindle cell lesions of the urinary bladder are uncommon tumors, and are most often spindle cell (sarcomatoid) carcinomas, non-neoplastic reactive mesenchymal proliferations, or soft tissue sarcomas. Inflammatory myofibroblastic tumors (IMTs) may also occur in this location, but IMTs occurring at bladder sites have rarely been described. We experienced a case of IMT of bladder.

국소성 피질이형성증의 외과적 치료

조관국,김형일,이민철,김근수,김연희,정창오,Neto, Pedro R. 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.12

Corticai Dysplasia(CD) is increasingly recognized as a cause of intractable epilepsy since it can be easily diagnosed with high resolution magnetic resonance imaging(MRI). We analyzed 24 consecutive cases with cortical dysplasia who underwent resective surgery at our institute between September. 1992 and December. 1995. MRI was demonstrated to be a decisive tool to identify CD in 16 cases(66.7%). However, the remaining 8 cases(93.9%) were confirmed to have CD based on histological examination. Location of the lesion included temporal(n=9), central(n=5), multilobar(n=5), and frontal(n=5). Intracranial EEG recording was performed to delineate the epileptogenic zons in 16 cases : subdural grid(10 cases) and depth electrode(6 cases). Resection was performed in temporal(n=9), frontal(n=7), central(n=5). parietal(n=1), and muitilobar(n=1). Complete resection was possible in 15(62.5%) and partial resection in 9(37.5%). Histological examination revealed dyslamination of cortical layers only(n=9), additional dysplastic neurons(n=7), and additional balloon cells(n=8). Surgical outcome was graded as seizure free(n=14 : 58.3%), rare seizures(n=3 : 12.5%). <50% reduction of seizure frequency(n=2 : 8%), and no change(n=5 : 20.8%) after mean follow-up of 12.7 months. The most influencing factor on the surgical outcome was the degree of completeness of resection(p<0.05). However. detectability of CD on MRI, severity of histological findings, age of seizure onset, and duration of seizure were not significantly related with the surgical outcome High suspicion is required to detect the CD among the patients with intractable epilepsy and surgical strategies should be well-planned to improve the surgical outcome in the patients with CD.

한국판 아동용 예일-브라운 강박 척도:신뢰도와 타당도 연구

정선주,이정섭,강윤형,조성진,서동혁,홍강의 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.1

목적 : 본 연구는 소아, 청소년의 강박 증상을 평가하기 위한 도구인 아동용 예일-브라운 강박척도(Childen's Yale-Brown Obsessive Compulsive Scale : Y-BOCS)의 한국판을 제작하여 그 신뢰도와 타당도를 검증하고자 시행되었다. 방법 : 강박장애로 진단된 42명의 아동과 청소년들을 대상으로 CY-BOCS를 시행하였다. 평가자간 신뢰도를 측정하기 위하여 20명의 환자를 2명의 평가자가 동시에 면담하였다. 수렴타당도와 변별타당도의 검증을 위해 총괄적인 임상 인상척도-강박장애(Clinical Global Impression-Obsessive Com-pulsive Disorder : CGI-OCD). 아동용 Leyton 강박 척도(Lryton Obsessional Inventory-Child Version : LOI-CV), 소아우울척도(Child Depression Inventory : CDI), 소아 상태-특성 불안척도(State-Trait Anxiety Inventory for Children : STAI-C)를 시행한다. 결과 : Cronbach's α값으로 평가한 내적 일치도는 0.86으로 높게 나타났다. CY-BOCS 전체 점수 강박사고, 강박행동 소척도 점수에 대한 군내 내적일치도는 각각 0.94. 0.94. 0.84로 우수한 평가자간 일치도를 보였다. CY-BOCS 전체 점수와 CGI-OCD 점수간의 상관관계는 매우 높게 나타났고(r-0.88), LOI-CY 총점과도 통계적으로 유의한 상관관계(r=0.51)가 관찰되었다. CY-BOCS 전체 점수와 STA-I-C의 상태불안 점수간에는 상관관계가 나타나지 않았고(r=0.25), 특성불안 점수(r=0.43) 및 CDI 점수(r=0.49)와는 유의한 상관관계를 나타냈다. 결론 : 본 연구결과, 한국판 CY-BOCS의 높은 타당도 및 신뢰도가 입증되었으며, 향후 강박 증상의 객관적인 평가 및 정량화를 위해 유용하게 사용될 수 있을 것이다. Objective : This study was carried out to evaluate the reliability and validity of the Korean form of the Children's Yale-Brown Obsessive Compulsive Scale(CY-BOCS). Method : Forty-two children with obsessive-compulsive disorder(OCD)(31 boys and 11 girls, aged 7 to 18 years) were assessed with CY-BOCS. Interrater agreement was assessed by two raters in subsample(n=20). discriminant and convergent validity were assessed by comparing CY-BOCS scores to Clinical Global Impression-OCD(CGI-OCD), Leyton Obsessional Inven-tory-Child Version(LOI-CV), State-Trait Anxiety Inventory for Children(STAI-C), and Child Depression Inventory( CDI ). Results : Internal consistency was high, measuring 0.86 for the 10 items and total score. The intraclass correlations for the CY-BOCS total, obsession, and compulsion scores were 0.94, 0.94, 0.84, suggesting excellent interrater agreement for subscale and total scores. The CY-BOCS total score showed highest correlation with CGI-OCD(r=0.88), and significant correlation with LOI-CV(r=0.51), Trait Anxiety score(r=0.43), and CDI scores(r=0.49), but it was not correlated with State-Anxiety score(r=0.25). Conclusion : The results of this study indicate that the Korean form of CY-BOCS is a reliable and valid scale for rating obsessive-compulsive symptom severity. KEY WORDS : Development · Rating scale · Obsessive-compulsive disorder · Reliability Validity.

흰쥐의 신경병증성 통증에 대한경피신경전기자극과 미세전류신경근자극

이윤주,이충휘,조상현,임중우,남택상 大韓再活醫學會 1999 Annals of Rehabilitation Medicine Vol.23 No.3

슬관절 전치환술시 슬개골 비치환술

조세현,정운화,천충우,윤영필 대한슬관절학회 2002 대한슬관절학회지 Vol.14 No.2

슬개골-대퇴골 관절의 합병증은 슬관절 전치환술 후 가장 흔한 합병증 중의 하나로, 이런 합병증을 예방하기 위해 슬관절 전치환술 시 슬개골을 치환할 것인가, 아니면 보존할 것인가에 대하여 아직도 많은 논란이 되고 있다. 1993년 8월부터 200년 8월까지 퇴행성 관절염 및 류마티스 관절염으로 슬개골 치환을 하지 않고 인공슬관절 전치환술을 시행한 환자 중 2년이상 추시가 가능했던 36명, 43례를 연구대상으로 하였다. 전례에서 슬개골의 퇴행성 변화에 관계없이 슬개골 보존술(즉 슬개골을 치환하지 않고 슬개골 성형술만 실시함)을 시행하였으며, 추시 기간은 최단 2년에서 최장 10년으로 평균 54개월이었다. 수술전 슬개골의 방사선 사진으로 정상 슬개골을 A군 (10례), 중등도의 퇴행성 변화를 B군 (20례), 심한 퇴행성 변화를 C군 (13례)으로 분리하여 세군의 슬관절 전방부 동통, 운동범위, 계단 오르기 능력 등의 임상적 소견과 슬개골 경사(patellatilt) 및 외측 슬개골 전위(lateral patella shift)의 두 가지 방사선사학적 소견을 비교 분석하였다. 35명중 퇴행성 관절염이 29명, 류마티스 관절염이 6명였으며, 임상적 분석은 American Knee Society Score(KSS)를 사용하였다. 최종추시시 평균 Knee Society Score (KSS)는 A군 93.1점, B군 92.7점, C군 94.2점이었다. 총 43례중 슬관절 전방부 동통을 호소한 예는 A군 2례, C군 2례로 4례 (9.3%)뿐이었으며, 이들은 보행 시는 동통이 없으나, 쪼그린 자세나 계단을 오르내릴 때 동통을 호소하였다. 세군간의 슬관절 운동범위, 계단 오르기 능력 등의 비교에서는 유의한 차이가 없었으며, 방사선학적 비교에서 외측 슬개골 전위는 유의한 차이가 없었고, 슬개골 경사는 A군과 B군에서는 유의한 차이가 없었으나, C군에서는 유의하게 차이가 있었으므로 술전 슬개골의 퇴행성 변화가 심할수록 슬개골 경사가 증가됨을 알 수 있었다(p=0.01). Patello-femoral problem is one of the common complications in total knee arthroplasty and whether to replace the patella or retain it has long been controversial in order to prevent the complications. 43 cases (35 patients) of total knee arthroplasty with patellar retention performed by single surgeon between August 1993 and August 2000 were reviewed retrospectively. The follow-up period averaged 54 months (range, 24-120months). The whole cases were divided into three groups according to the preoperative radiographs. Group A was normal patella (10 knees), Group B was borderline arthritic patella (20 knees), and Group C was severely deformed patella (13 knees). All of 43 knees, regardless of preoperative radiological degree of arthritis received patelloplasty including removal of osteophytes, subchondral shaving and lateral retinacular release was performed in 20 knees (47%). Each groups was evaluated in terms of the objective criteria of anterior knee pain, range of motion, stair climbing ability, and roentgenographic findings. All 35 patents were diagnosed as osteoarthritis in 29 and rheumatoid arthritis in 6. American Knee Society Score (KSS) was assessed for the clinical analysis and lateral patella shift and patella tilt were assessed for roentgenographic analysis. The mean Knee Society Score at final follow-up was 94 in group A, 93 in group B, and 94 in group C. Mild anterior knee pain was reported in 9.3% (Group A: 2 cases, Group C: 2 cases). patellar tilt was significantly higher in C group (oneway ANOVA test, p=0.01), representing that advanced patello-femoral arthritis caused increased patellar tilt. There was nither significant difference in terms of range of motion, and stair climbing ability nor of patellar shift among all three groups. TKA with patelloplasty, not resurfacing the patella, provided satisfactory results without significant problems regardless of the preoperative degree of patello-femoral arthritis.

情神分裂病 患者의 腦梁과 視床 : 腦 磁氣共鳴映像 硏究 Magnetic Resonance Imaing Study

조성연,강민희,이정섭 대한생물치료정신의학회 2002 생물치료정신의학 Vol.8 No.2

남성 정신분열병 환자에서 대조군에 비하여 뇌량무릎(genu)부위가 유의하게 작았으며 여성 정신분열병 환자군에서는 양군에서 차이가 없었다. 시상의 면적에서는 양군의 차이가 없었다. 이러한 결과는 남성 정신분열병에서 전전두엽의 크기가 작을 가능성을 시사하며, 또한 남성 정신분열병이 여성에 비하여 신경발달학적인 이상이 많을 가능성을 생각할 수 있다. Magnetic resonance imaging study about size of corpus callosum and thalamus of the shizophrenic patient. Many previous studies have been performed. But the result have been inconsistent. We studied with developed semiautomated measurement method. Using DSM-Ⅳ diagnostic criteria of schizphrenia, we selected 20 subjects and 22 controls. We measured area of corpus callosum and thalamus in midsagittal image with NIH image software. Divided 7 areas of corpus callosum as Witelson method and area of thalamus were measured. Significant difference was found in genu area of male corpus callosum, but no significant difference was found in female between schizophrenia and control. Above finding suggests that male schizophrenia may have neurodevelopmental abnormalities and prefrontal abnormalities.

아동 정신건강서비스에 대한 요구도 및 실제 이용에 관한 예비적 연구

김신영,조선미,임기영,정영기,신윤미 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.1

Objectives : We aimed to identily the degree of perceived need and use of child mental health services, and to examine the factors associated with the perceived need and use of the child mental health services. Methods : The sample consisted of 3,477 children aged 8 to 13 years. The parents completed the sociodemographic data, the Korean version of the Child Behavior Checklist (K-CBCL), and the Korean version of DuPaul's Attention Deficit Hyperacti-vity Disorder Rating Scale (K-ARS). Results : Overall, 10% of children demonstrated the need for mental health services, and 2.36% utilized the child mental health services. All subcategoiy scores of K-CBCL and K-ARS were significantly low in the no help needed group. Factor sassociated with the actual use ofchild mental health services included social problems and thought problems. Conclusion : The demand for child mental health services is high, but only a small number of children are using mental health services. To increase actual use, it is necessary to educate and campaign for various child mental health.

마우스의 장내 농양(intraabdominal abscess)형성에 대한 연구

박장환,정용훈,조양자,김정목,전윤홍 한양대학교 의과대학 1992 한양의대 학술지 Vol.12 No.1

Intraabdominal abscesses (IAA) are produced microbiologically by mixed infection. And clinical treatment of IAA is limited because duration of the these diseases are prolong and the their nature is mixed infection. This study was carried out to develop a standardized IAA model used in B.fragilis. Encapsulated B.fragilis and autoclaved colonic and cecal contents produced IAA> And encapsulated B.fragilis produced IAA more than unencapsulated B. fragilis. Only E.coli was not effective to produce IAA but combination with encapsulated B.fragilis produced IAA. Abscesses were usually found in the serosal surface adherent to pancrease or colon and in the fatty tissue around the uterus. This study will subsequently support a development of IAA treatment.

BaO-Al₂O₃-SiO₂계 유리의 결정화

이희수,조동현,정윤중 연세대학교 산업기술연구소 1981 논문집 Vol.13 No.1

In the study of dielectric properties and structure for the BaO-Al₂O₃-SiO₂ system glass ceramics, the following results were obtained: 1. The parent glass batch for 36BaO-24TiO₂-36SiO₂-6Al₂O₃for mula melted when it at was heated at the 1520℃ for 2hrs. 2. The two crystals, Barium titanate and Barium celsian, existed together in the glass ceramics of this system. It was observed that the Barium titanate controls the crystallizatton. As the crystallinity of Barium tiatate was increased, the dieliectric constant was increased in the glass of this system. The variation of dielctric loss factor was slightly increased. 3. The conditions which have the large value of the crystallinity of Barium titanate and the uniform distribution of the crystal are the heating temperature of 650˚C and the soaking time of 3hrs for nucleation and 1150℃ and 5hrs for crystallization. The crystallinity was 35wt% and the dielectric constantwas 400.

학국에서 심방세동의 임상양상에 관한 연구

이선미,조정휘,홍순조,최윤식,안신기,김성순,김영훈,김윤년,조정관,차태준,김유호,최기준,김준수,이상민,신동구 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.5