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조덕봉,마상조,최춘순,이송주,최옥범 광주보건대학 1997 論文集 Vol.22 No.-
The various components and antimicrobial activities of Pona cocos were studied to obtain the basic data as giving many applications. In the results of analysis of fatty acids compositions, it consist of stearic acid as saturated fatty acid, and oleic acid, linoleic acid as unsaturated one. The Pona cocos was extracted with methanoi and its extracts were determined to be antimicrobial activities against bacteria and yeast. Methanoi extracts of the Poria cocos showed stronger antimicrobial activities on Staphylococcus aureus, Staphylococcus epidermidis. Bacillus subtilis, Micrococcus luteus, Leuconostoc mesenteroides, Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa than control, benzoic acid. In conclusion, Poria cocos extracts showed antimicrobial activities and will be required to isolate and identify substance with antimicrobial activity as functional materials.
馬相朝,趙德鳳,金東弼,崔春淳,李松周 광주보건대학 1988 論文集 Vol.13 No.-
As a result of research on the present condition of the department relating to food at the junior college as of 1987 in our country, the number of the departments are 23 cases and the full-time professors are 132 persons and the number of students are 3,760 persons. This study can see that our country has attached importance to food science education as fourfold in the number of students comparing with that of 1971. The character of the curriculum is different according to its systems, but it has the subject that need to train the major technicians and graduating students advance into each field. Because of great many of students who are trained in a field of food science, it can be said that further the food industry and the development of food science have good prospects. Food science is recognized as important thing to everyone due to a serious problem of food in accordance with the population growth and gradual scientific propulsion of the national dietary life. With the basis of the analytical about the curriculum of the department relating to the food of university and junior college in internal and external and the result that is analyzed students and teachers' replies by the questionaire, this study makes out a model plan of te curriculum in junior college like table 14. Though the curriculum is ideal and perfective, as if it is not governed well nothing can be obtained, the other way also even though the curriculum is not perfect, if the mystery of management is praciced, a good results can be getting. Especially modern creative way of field practice makes students themselves set up purpose to learn and look for its meaning, and as experimenting and confirming their own thought and ability through solution of problem it helps to get developed and made up theirs own self. Therefore constitution of course of the field pratice is established centering around the experence of students to set studying purpose. It is continuously managed to do the ideal studying by change of a time and demand of society, and also should be recognized to build up ability that judge and decide as theorizing a lot of knowledge on the conceptional and theorical basis. In the way that the department of food processing at a junior college should improve, improvement of educational equipment is urgent, then the cost of equipment should be secured and the curriculum should be improved. Finally, thank for every junior college who cooperate with this study and such study for more better fixed curriculum will be continued after this report. So there will be sufficient results.
Song, Ki-Duk,Cho, Hyun-Woo,Lee, Hak-Kyo,Cho, Byung Wook Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.5
The objective of this study was to determine the molecular characteristics of the horse vascular endothelial growth factor alpha gene ($VEGF{\alpha}$) by constructing a phylogenetic tree, and to investigate gene expression profiles in tissues and blood leukocytes after exercise for development of suitable biomarkers. Using published amino acid sequences of other vertebrate species (human, chimpanzee, mouse, rat, cow, pig, chicken and dog), we constructed a phylogenetic tree which showed that equine $VEGF{\alpha}$ belonged to the same clade of the pig $VEGF{\alpha}$. Analysis for synonymous (Ks) and non-synonymous substitution ratios (Ka) revealed that the horse $VEGF{\alpha}$ underwent positive selection. RNA was extracted from blood samples before and after exercise and different tissue samples of three horses. Expression analyses using reverse transcription-polymerase chain reaction (RT-PCR) and quantitative-polymerase chain reaction (qPCR) showed ubiquitous expression of $VEGF{\alpha}$ mRNA in skeletal muscle, kidney, thyroid, lung, appendix, colon, spinal cord, and heart tissues. Analysis of differential expression of $VEGF{\alpha}$ gene in blood leukocytes after exercise indicated a unimodal pattern. These results will be useful in developing biomarkers that can predict the recovery capacity of racing horses.
Cho, Hyun-Jong,Termsarasab, Ubonvan,Lee, Song Yi,Maeng, Han-Joo,Kim, Dae-Duk,Yoon, In-Soo American Scientific Publishers 2017 Journal of nanoscience and nanotechnology Vol.17 No.4
<P>Gold nanoassemblies (AuNAs) stabilized by chitosan oligosaccharide (CSO), chitosan oligosaccharide-arachidic acid (CSOAA), and chitosan oligosaccharide-arachidic acid-polyethylene glycol (CSOAA-PEG) were fabricated and evaluated. CSOAA was synthesized by amide bond formation between CSO and arachidic acid (AA), and CSOAA-PEG was then prepared by amide bond formation between CSOAA and methoxypolyethylene glycol succinimidyl succinate (mPEGSS). All AuNAs, such as CSO-stabilized AuNA (C/AuNA), CSOAA-stabilized AuNA (CA/AuNA), and CSOAA-PEG-stabilized AuNA (CAPE/AuNA), exhibited < 150 nm hydrodynamic size in the aqueous environment. Unlike C/AuNA and CA/AuNA groups, CAPE/AuNA exhibited similar particle size in aqueous buffer and serum conditions as well as in water. The results of surface plasmon resonance (SPR) measurement provided corresponded particle size of all AuNA groups, which determined by an electrophoretic light scattering (ELS) method. Developed AuNAs also did not show serious cytotoxicity in A549 (human lung adenocarcinoma) and U87-MG (human glioblastoma) cells within tested Au concentration range. Conclusively, CAPE can be used for the fabrication of hybrid AuNAs which are stable in the blood stream.</P>
Common genetic variants at 1q22 and 10q23 and gastric cancer susceptibility in a Korean population.
Song, Hye-Rim,Kim, Hee Nam,Kweon, Sun-Seog,Choi, Jin-Su,Shim, Hyun Jeong,Cho, Sang Hee,Chung, Ik Joo,Park, Young-Kyu,Kim, Soo Hyun,Choi, Yoo-Duk,Joo, Kyung Woong,Shin, Min-Ho Saikon Pub. Co 2014 TUMOR BIOLOGY Vol.35 No.4
<P>Genetic variants at 1q22 and 10q23 were identified as genetic markers of both gastric cancer and esophageal squamous cell carcinoma susceptibility by two genome-wide association studies. The aim of this study was to determine whether rs4072037A > G in MUC1 at 1q22 and rs2274223A > G in PLCE1 at 10q23 are associated with a risk of gastric cancer in a Korean population. We conducted a large-scale case-control study of 3,245 patients with gastric cancer and 1,700 controls. The allele frequencies of rs4072037G and rs2274223G were 11.2 and 25.5% among patients with gastric cancer, compared with 12.8 and 26.4%, respectively, among controls. We found that the rs4072037 AG genotype was significantly associated with a reduced risk of gastric cancer [odds ratios (OR)?= 0.78; 95% confidence interval (CI)?= 0.67-0.91 for AG vs AA]. Compared with the rs2274223 AA genotype, we found a significant association between the rs2274223 AG genotype and a weakly reduced risk of gastric cancer (OR = 0.87; 95% CI = 0.76-0.99 for AG vs AA). Our data suggest that genetic variants at 1q22 and 10q23 play a role in gastric carcinogenesis.</P>
Cho, Hyun-Woo,Shin, Sangsu,Park, Jeong-Woong,Choi, Jae-Young,Kim, Nam-Young,Lee, Woon-Kyu,Lee, Hak-Kyo,Song, Ki-Duk,Cho, Byung-Wook Asian Australasian Association of Animal Productio 2015 Animal Bioscience Vol.28 No.5
While athletic abilities such as speed, endurance and recovery are important in the horse, genes related to these abilities have not been extensively investigated. Here, we characterized the horse peroxisome proliferator-activated receptor delta ($PPAR{\delta}$) gene and analyzed the expression of $PPAR{\delta}$ during exercise. $PPAR{\delta}$ is a known regulator of ${\beta}$-oxidation, muscle fiber transformation, and running endurance. Through evolutionary analysis using the synonymous and non-synonymous mutation ratio, it was revealed that positive selection occurred in the horse $PPAR{\delta}$ gene. Two important domains related to nuclear hormone receptors, C4 zinc finger and ligand binding domain, were also found to be conserved well in horse $PPAR{\delta}$. Horse $PPAR{\delta}$ was expressed ubiquitously in many tissues, but the expression level was various depending on the tissues. In the skeletal muscle, $PPAR{\delta}$ increased about 2.5 folds after 30 min of exercise. Unlike in muscle, the increase of $PPAR{\delta}$ expression was observed at 60 min but not 30 min of exercise in leukocytes. This finding might be useful for testing the endurance of horse using blood samples. Conclusively, the horse $PPAR{\delta}$ gene is evolutionarily conserved well and can be used as a biomarker of endurance in horse.