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서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1
일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.
Ⅲ급 부정교합의 수술-교정 치료시 상악 소구치 발치가 치열궁 폭경 변화에 미치는 영향
이신재,홍성준,김영호,백승학,서정훈 대한치과교정학회 2005 대한치과교정학회지 Vol.35 No.1
본 연구에서는 Ⅲ급 수술-교정 치료 방법에 영향을 미치는 치열 상의 요소를 파악함으로써 술전 교정시 상악 소구치 발치와 비치의 판단에 필요한 임상적 정보를 얻고자 골격성 Ⅲ급 부정교합 환자의 수술-교정 치료시 흔히 선택되는 상악 제1소구치 발치로 치료된 군과 비발치로 치료된 군 간의 치료전/후 상/하악 개별 치아 이동 양상과 치열궁 폭경의 변화 양상을 비교 분석하였다. 이를 위하여 비발치로 Ⅲ급 수술-교정 치료를 마친 환자 (24명) 와 술전교정 치료시 상악 제1소구치가 발치된 환자 (31명) 의 치료 전/후 모형 상에서 개개 치아의 근원심/협설측 각도변화와 상/하 치열궁 폭경의 변화를 측정한 후, 두 군 사이의 교정적 치아 이동 양상을 비교 분석한 후 상/하 치열궁의 조화를 이루는데 필요한 치열궁 폭경의 변화와 이에 기여하는 치아 변위와의 관계를 분석하기 위하여 상관 분석과 회귀 분석을 시행한 결과 발치 군은 비발치 군에 비하여 상악 치열궁 폭경의 감소가 컸으며, 이는 상악 구치의 inclination 감소에 크게 영향 받은 것으로 관찰되었다. 하악 치열에서는 inclination의 증가와 폭경의 증가가 있었으나, 비발치/발치군간의 차이는 유의하지 않았다. 본 연구의 결과 결론적으로 Ⅲ급 수술-교정 치료시 술전 상악소구치 발치는 상악 구치부 치열궁 폭경의 감소에 크게 영향을 미치므로, 상악 소구치 발치에 대한 판단은 상/하악 치열궁의 폭경 및 구치부 경사도 문제와 연계하여 고려해야 할 사항으로 생각되었다. Collective changes caused by orthodontic tooth movement evaluated in a specific treatment modality could give suggestive information on the specific treatment strategy. The aim of this study was to investigate retrospectively the characteristics of the orthodontic tooth movement during surgical-orthodontic treatment in order to provide an effective presurgical orthodontic treatment planning for the maxillary premolar extraction modality in the skeletal Class Ⅲ malocclusion patient. Pre- and post-treatment dental casts of skeletal Class Ⅲ malocclusion patients with nonextraction (N=24) and the maxillary premolar extraction (N=31) were collected. The angulation and inclination measuring gauge (Invisitech Co. Seoul, Korea) was used to evaluate the orthodontic tooth movement. The changes in the maxillary and mandibular dental arch widths were also measured from the canines to the second molars. As a result, more palatal Inclination change in the maxillary dentition was found with the premolar extraction modality than with the nonextraction modality. Linear regression analysis showed that the inter-arch width coordination was mainly due to the inclination changes of maxillary posterior teeth. We conclude that the indications and proper treatment planning for surgical-orthodontic treatment in skeletal Class Ⅲ malocclusion with maxillary premolar extraction could depend partly on the magnitude of the transverse inter-arch coordination especially in the maxillary dentition.
이청림,이명호,김태호 한국경영과학회 2002 經營 科學 Vol.19 No.2
As the business structure of many industries changes under IT progress and internet economy, the customer information has emerged a key factor in setting up the management policy. The customer has come to replace the product as a central figure in business competition. The domestic life insurance market has also experienced the rapid structural changes in IT time. The competition in the insurance industry to maintain the existing membership and to attract the new members gets stronger under such a new business circumstance. Accordingly, it is necessary for an individual insurance company to develop a systematic marketing plan, based on the customer information, to be competitive in the market. Unlike other studies in which customer characteristics are neglected, this study attempts to utilize the customer information by applying the data mining technique, and then suggests an efficient marketing strategy that could prevail in the competitive business environment.
뇌자도 측정을 위한 저잡음 Nb SQUID 센서의 설계 및 제작
이용호,권혁찬,김진목,이상길,임청무,박용기,박종철 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1
We report on the design, fabrication and performances of a low-noise Nb SQUID sensor for neuromagnetic measurements. The main features of the developed sensor are i) large flux-to-voltage transfer, making the SQUID readout electronics simple, and ii) use of the integrated planar pickup coil to eliminate the environmental magnetic field noises. The magnetic field noise of the developed SQUID sensor is below 5 fT/√Hz at 100 Hz, which is low enough to be used in neuromagnetic measurements.
과학 용어 분류를 통한 초등학생들의 심리적 과학 영역 분석
이성호,임청환,정진후 한국교원대학교 과학교육연구소 2001 청람과학교육연구논총 Vol.11 No.1
통합적인 과학 교육의 필요성이 부각되고 있으며 통합 방안에 관한 여러 연구들이 이루어지고 있다. 그러나 대부분의 통합에 관한 연구는 학문의 구조와 인식론적인 측면에 그 근거를 두고 이루어지고 있다. 보다 효율적인 통합 과학 학습을 위해서는 학생들의 심리적인 측면에 관한 연구가 이루어져야 한다. 이러한 필요성에 의해 본 연구에서는, 초등학교 6학년 96명을 대상으로 교육과정상의 과학 용어 분류를 통하여 초등학생들의 심리적인 과학 영역과 그 특징을 알아보았다. 연구 결과, 다양한 과학 영역을 형성하고 있는 것으로 나타났으며 특히 ‘전기’, ‘인체’, ‘지구’, ‘에너지’, ‘식물’, ‘동물’, ‘환경’, ‘생물’, ‘날씨’, ‘꽃’의 빈도가 높게 나타났다. 각 영역에 포함된 과학 용어를 분석한 결과는 다음과 같다. 첫째, 일상 생활의 경험에서 형성된 관련성을 강하게 유지하고 있는 경우가 있었다. 둘째, 가장 포괄적인 영역은 ‘지구’영역이었다. 이 영역에는 다른 영역에 포함되었던 대부분의 용어들이 관련되고 있었다. 따라서 ‘지구’영역을 통합의 중심으로 하는 것은 학생들의 심리적인 측면에도 잘 부합되는 것이라고 보여진다. The importance of integrated approach have increased gradually in science education. But most of researches on integrated science have been based on the structure of science and epistemology. The investigations of students' psychological science domains are needed for effectiveness of integrated science in science curriculum and classrooms. In this study, for exploration of elementary school students' psychological science domains and their properties, students(N=96) were asked to classify scientific words presented on textbooks in several categories. Many psychological science domains were revealed. Among them, the domains that were over 20% are 'Electricity', 'The human body', 'The earth', 'Energy', 'Plant', 'Animal', 'Environment', 'Living things', 'Weather', 'Flower'. According to the results from analysis on the words that students presented in each domains, the participants hold strongly the relationships caused by everyday experiences. For example, 'light' and 'heat' showed high frequency in 'Electricity' domain and 'The human body' domain included 'force' and 'motion' in high frequency. The most inclusive domain was 'The earth'. Not only the words on earth science but also biological and chemical words were classified in this domain. So The integration that centered with 'The earth' domain looks correspond to the elementary school students' psychological aspect.
마이크로니들의 형태 및 적용방법이 약물의 피부 투과에 미치는 영향
임지호,이경록,이은주,조정원 충남대학교 약학대학 의약품개발연구소 2012 藥學論文集 Vol.27 No.-
The purpose of this study is to develop the microneedle using biodegradable and biocompatible polymer and to pioneer the new route of drug delivery through the research to apply the most desirable administration form of small molecules, peptides, proteins, genes, biological products including vaccines. Various biocompatible microneedles were manufactured. To apply drug to microneedle, drug formulation using ethylene vinyl acetate patch or polyacryl acid gel was developed. Drug permeation into rat skin based on the application method of patch or gel with microneedle was studied using Franz diffusion cell system. In vitro drug permeation results showed that the permeation by the application of hollow microneedle was not increased compared with solid microneedle. When G60 or G60*2 microneedle was used, the permeated amount of calcein was increased compared to when solid microneedle was used. The permeated amount of lidocaine HCl in 12 hr was increased when microneedle was used was increased. Skin irritation followed by microneedle showed there was little difference in the decrease of redness after microneedle application based on application time.
오정환,이종호 忠南大學校體育科學硏究所 2002 體育科學硏究誌 Vol.20 No.1
The purpose of this study was to identify kinetics factors during the two-step vertical jump. Two college students representing college were participated as the subject. The three-dimensional visual analysis and ground reaction were used for the purpose of this study. The results of this study were as follows: (1) the time spent jump took 0.13 seconds and the height of jump was 63.55cm during two-step vertical jump: (2) the speed of upper segment were appeared in order hand, forearm, upper arm, trunk and the lower segments were the thigh and crus in order during two-vertical jump: (3) the angles of shoulder joint, hip joint, knee joint, and ankle were 94.1°, 105.2°, 116.4°, and 84.2°, respectively during taking arms back: (4) the speeds of shoulder joint, knee joint, ankle joint, hip joint were 1926.9deg/sec, 626.6deg/sec, 546.4deg/sec, and 368.4deg/sec, respectively: (5) the vertical speed of the central gravity on body was 362.1cm/sec and the force that was applied to vertical was 1154.2N/sec during the two-step vertical jump: (7) hands, forearms, upper arms, trunk, and head were going down and feet, lower limbs, and thigh were going up vertically during the two-step vertical jump.