백서 심근경색모델에서 시간경과와 경색의 크기에 따른 심자도의 변화

김미성(Mi Sung Kim),박영선(Young Sun Park),권순길(Sun Gil Kwon),지정훈(Jeong Hoon Ji),신종성(Jong Sung Shin),오광식(Kwang Sik Oh),양용모(Yong Mo Yang),연태진(Tae Jin Youn),김동운(Dong Woon Kim),조명찬(Myeong Chan Cho),이용호(Yong Ho 대한내과학회 2002 대한내과학회지 Vol.62 No.1

N/A Background: Magnetocardiogram (MCG), which records the changes of magnetic fields generated by the heart`s electrical activity, theoritically can provide unique data for clinical application. To date, MCG has been investigated only at a single time point after myocardial infarction (MI) with severe left ventricular dysfunction in rats. The purpose of the present study was to investigate sequential changes of MCG after MI and to evaluate effects of infarct size on MCG. Methods: Acute MI were induced by the permanent ligation of left coronary artery in 22 rats. Magnetic fields were recorded just above a rat with Nb Superconducting Quantum Interference Device (SQUID) gradiometer inside a magnetically shielded room. MCG was measured before and immediately after surgery and it was subsequently recorded at the time points of 1, 4 and 6 hours post operatively. MCG was also measured at 1, 3, 7 and 21 days after surgery. Results: Elevation of ST segment and appearance of pathological Q wave on the MCG were evident immediately after the ligation of coronary artery and persisted to 6 hours after MI. On MCG, ST segment was depressed and T wave was inverted from 1 day after MI. In rats with small-and moderate- sized MI (infarct size〈30%), ST depression returned to near the isoelectric level and Q wave disappeared from 7 days after MI. However, ST depression and Q wave were still present in rats with larger infarct (infarct size≥30%). Conclusion: Evolutional changes of MCG were well-recognized up to 21 days after MI. Furthermore, the infarct size can be expressed by the extent of Q wave and ST segment depression on MCG. Taken together, these data indicate that MCG is a helpful modality for the diagnosis, evaluation of infarct size and follow up after MI.(Korean J Med 62:42-48, 2002)

유아의 사회적 역할놀이에 대한 교사들의 인식

박찬옥,정남미 中央大學校 韓國敎育問題硏究所 1996 韓國敎育問題硏究所論文集 Vol.- No.11

The purposes of this study were to examine the patterns of teacher intervention in children's sociodromatic play at kindergarten, to investigate the perception of teachers concerning sociodramatic play, and to grope the effective strategies of teacher intervention. The results of this study were as follows ; 1. Most of kindergarten had settings and objects for sociodramatic play. However, they were limited to play house and household appliance. 2. Most of Kindergarten teachers recognized that sociodramatic play had influence on social, emotional, language development for children, and most of them involved in sociodramatic play for supporting and activating. 3. But most of them didn't make lists of props (equipments) and plans for sociodramatic play. 4. In general, they eveluated children's sociodramatic play. 5. The pre-service and in-service teacher traing for the effective intervention methods of sociodramatic play didn't well excute. 6. The effective intervention strategies contains changing the play themes, sharing the background informations for them, providing sufficient time, space, props, and teachers' prompting by the steps of planing, developing, and evaluating about the play activity.

눈꽃동충하초(Paecilomyces japonica)를 첨가한 증편의 미생물학적 품질특성 및 저장성

박찬성,최미애,박금순 한국조리과학회 2004 한국식품조리과학회지 Vol.20 No.6

The purpose of this study was to investigate the effect of Paecilomyces japonica mycelia(PJM) on pH, titrable acidity and microbiological quality of Jeungpyun(fermented rice cake). Jeungpyun prepared with 0?7% of PJM stored at 5℃ and 20℃ for 4 weeks and 7 days respectively. Before fermentation of Jeungpyun dough, viable cells of total bacterial counts(TBC), yeasts and lactic acid bacteria(LAB) were 6.0~9.8×10^6, 5.3~9.0×10^(6), 5.4~8.5×10^(6) CFU/g, respectively. During the fermentation of dough, viable cells of TBC, yeasts and LAB increased 0.3~0.4 log cycle and pH was decreased whereas acidity incresed as the progress of fermentation. Total viable cells in Jeungpyun before storage were 5.0×10¹ CFU/g. During storage of Jeungpyun, TBC, yeasts and LAB of control group increased 2.6, 2.4, 2.1 log cycle at 5℃ and 4.8, 4.6, 4.5 log cycle at 20℃, respectively, when reached at maximum level. Major microflora of Jeungpyun was composed of yeasts and LAB during fermentation of dough and storage at 5℃ and 20℃. Addition of PJM, inhibited the growth of microorganisms, the changes of pH and titrable acidity of Jeungpyun during storage at both of 5℃ and 20℃. From these results, the addition of PJM extended the shelf-life of Jeungpyun during storage at 5℃ and 20℃.

복합트레이닝이 비만청소년의 내장지방과 면역세포에 미치는 영향

박상갑,윤미숙,권유찬 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

The purpose of this study was to investigate the changes of abdominal fat, lymphocyte subunits and NK cell after lBweeks combined training, Subjects were consisted of fourteen obese middle-school students, The training program was separated treadmill running and muscular resistance training. The treadmill running was composed of 60%HRmax(Intensity), 30 minutes per day(Duratiori), 4 days per week(Frequency). The muscular resistance training was composed of 60% of 1RM[(Intensity), 40 minutes per day(Duration), 4 days per week(Frequency). One-way ANOVA was used to evaluate change between groups. We found that VO₂max(0.34ℓ/min) was increased after 16 weeks combined training and %body fat(3.01%), total abdominal fat(158.98㎤), visceral fat(76.69㎤), subcutaneous fat(82.29㎤), visceral at and subcutaneous at ratio(0.10) were significantly decreased after 16 weeks combined training, Furthermore lymphocyte subunits and NK cell number were improved after 16 weeks combined training. In conclusion, combined training was shown to positive influence on body coposition, lymphocyte subunits and NK cell, Therefore, it is maybe thought that combined training was important role for obesity treatment.

장기간의 복합트레이닝이 중년 남녀의 스포츠 의학적 변인에 미치는 영향

박상갑,권유찬,윤미숙,김은희 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.5

The purpose of this study was to investigate the changes of sports medicine variables after 20weeks combined training. Subjects were consisted of 130 middle-aged males and females. The training program was separated treadmill running and muscular resistance training. The treadmill running was composed of 60-70% HRmax(Intensity), 30 minutes per day(Duration), 5 days per week(Frequency). The muscular resistance training was composed of 70% of 1RM(Intensity), 40 minutes per day(Duration), 5 days per week(Frequency). multiple ANOVA was used to evaluate change times. We found that weight, BMI %body fat, SBP and DBP were significantly decreased and LBM was significantly increased after 20 weeks combined training. In conclusion, combined training was shown to positive influence on body composition and blood pressure. Therefore, it is maybe though that 20 weeks combined training will benefit the prevention of life style related diseases.

취학전 아동의 下衣構成을 위한 下肢 皮膚面의 形態變化分析

朴贊美,徐美亞 漢陽大學校 韓國生活科學硏究所 1995 韓國 生活 科學 硏究 Vol.- No.13

This study aimes to inverstigate the changes of sgape of the Lower limb surface, the rate of the measurement of expansion and contraction caused by hip joint and knee joint movements. The replicas of the lower trunk and the lower limb surface were taken by using a gypsum method on 4 pre-shcool chdrens subjects under 5 standardized lower limb positions. Those replicas obtained were developed to the patterns and the changes in shope and area of those were measured. The characteristics of regional body surface changes were summarized as follows ; 1.The surface changes in the lower trunk and the lower limb seemed to be influenced directly by the direction and the amount of lower limb movement. 2.As a result of investigating into the rate of the expansion and contraction of the body surface area by the lower limb movements, the back area of the hip showed the maximum rate of expansion. 3.The rate of changes in the horizontal direction were little. The hip girth and knee girth showed the large rate extentions in flexion 90 at both the hip and knee joint. Therefor, when the lower clothing contrution for pre-school children at least the amount of ease of 1.0cm of hip girth and 3.5cm of knee girth must be made. 4.The changes in the vertical direction were apparently more than those in the horizontal one. This meant that the changesof the body surface area previously reported were largely effected from the changes in vertical direction. The center back line showed the maximum rate of extension. So when the lower clothing construction for pre-school children at least the amount of ease of 4.7cm dncenter back line must be made.

배지의 종류가 식중독세균의 열손상으로 부터 회복에 미치는 영향

박찬성,김경희,김미림 慶山大學校 1994 論文集 Vol.12 No.1

10^6 - 10^7 cells/ml of pathogenic bacteria, vibrio parahaemolyticus 10135, Staphylococcus aureus 196E and Listeria monocytogenes were exposed at 45, 50 and 60℃ for 60 minutes in tryptic soy broth(TSB). Following thermal stress, cells were allowed to recover in three kinds of recovery media for 24 hour. TSB, Flounder homogenate and Oyster homegenate were used for heat injured Vibrio parahamolyticus and Staphylococcus aureus where as TSB, Listeria enrichment broth(LEB) and Oyster homogenate for Listeria monocytogenes as recovery media. Heat injury of Vibrio parahamolyticus was larger Staphylococcus aureus or Listeria monocytogenes at 50℃. Recovery of heat injured cells of Listeria monocytogenes was laster than other strains. TSB was a good media for recovery of heat injured cells but Oyster homogenate was poor.

복합트레이닝이 비만중년여성의 복부지방과 IGF-Ⅰ에 미치는 영향

박상갑,권유찬,윤미숙 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

The purpose of this study was to investigate the changes of O₂max, abdominal fat, serum lipid and IGF-I concentration after 12weeks combined training. Subjects were consisted of fourteen obese middle-aged women. The training program was separated treadmill running and muscular resistance training. The treadmill running was composed of 70%HRmax, 60 minutes per day, 3 days(mon, wen, fri) per week. The muscular resistance training was composed of 70% of 1RM, 60 minutes per day, 2 days(tue, thur) per week. The levels for abdominal fat volume were measured by determining the subcutaneous fat volume(SFV), visceral fat volume(VFV), and VFV/SFV by CT(computed tomography). The VO₂max(㎖!/㎏/min) was significantly increased. The subcutaneous fat and visceral fat levels were decreased in combined training group. In addition, HDL-C, Apo A-I, IGFBP-3 were increased, and LDL-C, Apo B were decreased after 12weeks combined training. In conclusion, combined training was shown to positive influence on abdominal fat, serum lipids, and IGFBP-3. Therefore, it is maybe thought that combined training was important role for obesity treatment.

근저항 트레이닝이 비만중년여성의 복부지방에 미치는 영향

박상갑,권유찬,윤미숙 東亞大學校 2001 東亞論叢 Vol.38 No.-

The purpose of this study was to investigate the effect of muscular resistance training on abdominal fat. Subjects were composed of sixteen obese middle-aged women. Resistance training was performed 60minutes per day, 5days per week at 60% of 1RM during 1~12weeks and at 70% of 1RM during 13~24weeks. The items for abdominal fat volume were measured subcutaneous fat volume(SFV), visceral fat volume(VFV), VFV/SFV by computed tomography. Paired t-test was used to evaluate the difference of baseline and after 24 weeks muscular resistance training. The 0.05 level of significance was as critical level for the study. The results of this study are as follow; 1. Body weight and %fat were significantly(p<.05) decreased in muscular resistance training group. 2. VFV and SFV were significantly decreased in muscular resistance training group. 3. VFV/SFV was significantly decreased in muscular resistance training group. In conclusion, visceral fat and subcutaneous fat were decreased in muscular resistance training. So it is maybe thought that long-term muscular resistance training improved body composition for obesity treatment.

난소에 전이된 간세포암 1예

박용관,박치영,조은택,조기섭,박찬국,송창훈,이미자,기근홍 朝鮮大學校 附設 醫學硏究所 1995 The Medical Journal of Chosun University Vol.20 No.2

Hepatocellular carcinoma frequently metastasizes through direct extension, lymphatic, and hematogenous routes. The most common sites of metastasis are the lungs and the lymph nodes, glands, bones, spleen, kidneys, colon, and pleura are the sites of metastasis in decreasing order of frequency. But metastasis to the ovary is very rare. It is thought that metastasize to the ovary occurs through infiltration or dissemination. However, we observed ovarian metastasis of primary hepatic tumor in a 34-year old female who suffered from lower abdominal pain. At first, it was diagnosed as a primary ovarian tumor. But histologically, it presented sinusoidal pattern surrounded by the tumor cells and contained rounded by the tumor cells and contained round hyaline globules in minority of the cytoplasm. Then, the histologic features of percutaneous, sono-guided liver biopsy speecimen of the liver mass are similar to those of resected ovarian tissues. Therefore, we concluded that ovarian tumor was originated from hepatocellular carcinoma. In summary, this report examines a case of hepatocellular carcinoma with ovarian metastasis in a female and reviews the literature.