用寒遠寒과 用熱遠熱에 대한 考察 : 六元正紀大論에서

채영진,신창환,임현택,여성원,한성규,이재원,정헌영,금경수 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

Five elements motion and six kinds of natural factors influence not only human disease but also difference of medicine effect. Because the climate of summer is very hot, that is easy to increase the properties of hot medicines, a doctor must be careful to use it in summer. Also the climate of winter is very cold, that is easy to increase the properties of cold medicines, a doctor must be careful to use it in winter. But in the certain conditions to use diaphoretics or purgatives, in spite of that regulation a doctor can use them.

十二變에 대한 考察 : 六元正紀大論을 중심으로

채영진,남호현,이석모,여성원,한성규,이재원,안민식,정헌영,금경수 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

The six kinds of natural factors(It refers to wind, cold, summer-heat, dampness, dryness and fire.) is constantly moving to maintain the balance of whole climate of one year. Four seasons are the largest mediation of whole climate of one year. The cold and the heat have the relationship of mutual intervention. The dampness and the dryness have it also. In this process they raise various climate appearance. And that various climate appearance influence the whole lives on the earth. This paper is concerned with the classification of them.

Superconducting MgB2 Wire Drawing Considering Anisotropic Hardening Behavior and Hydrostatic Effect

Young‑Seok Oh,Ho Won Lee,Kook‑Chae Chung,Duck‑Young Hwang,Seong‑Hoon Kang,Jeong Whan Yoon 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7

Numerical modeling was conducted to investigate the deformation behavior of powder mixture during multi-pass drawingprocesses for multi-filamentary MgB2wire. A modified Drucker-Prager Cap (DPC) model with an elliptical cap surface usingthe new material characterization method was developed to capture the anisotropic hardening behavior and hydrostatic effectof the powder mixture. A number of uniaxial die compaction, cold isostatic pressing, diametrical compression, and uniaxialcompression tests were conducted using different powder densities to characterize the modified DPC model. A commercialfinite element software ABAQUS with a user subroutine was used to simulate the drawing of the MgB2wire. The densityand area fraction of the powder mixture during the wire-drawing process were verified with experimental results. The differencein packing density at the inner and outer filaments of the MgB2wire was successfully captured by simulation. Inaddition, the effect of the initial packing density on the superconducting properties of MgB2wire was numerically studied. It is shown that the increase in the superconducting area, which results from a high initial packing density, should be moreeffective compared to the increase in the grain connectivity in enhancing the critical current properties for the MgB2wirewhen the final packing density is saturated after a number of drawing processes.

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

갑상선 결절의 임상양상과 미세침흡인검사의 의의

원진호,한희정,채수홍,김현진,송민호,김영건 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

We evaluated clinical manifestation of nodular thyroid disease and fine-needle aspiration cytology results to establish an appropriate diagnostic approach to thyroid nodule. We examined 594 patients who visited Chungnam National University Hospital with one or more thyroid nodules between Jan. 1996 and Dec. 1998. Fine-needle aspiration cytology was carried out after clinical evaluation including medical history, physical examination(hardness,size, multinodularity,fixation) and laboratory test(scan, thyroid function test). Among the 594 cases, 53 cases(8.9%) were diagnosed as cancer and 457 cases(77%) were diagnosed as benign nodule. None of these factors - age, sex. soft and firm nodule, multinodularity, thyroid scan, thyroid sonography, and thyroid function test - were significant to predict cancer in our study. The prevalence of cancer was significantly higher in hard nodule(28. 5%,39/137) than firm(3.8%,12/316) or soft nodule(0%,0/72). There was size difference between malignant(24.2±62.8ml) and benign nodules(12.6±26.1ml),but the size difference wasn't shown to an indicator to say whether malignant or benign. The prevalence of cancer in relation to fixation was significantly higher in fixation(50%,19/38) and partial fixation nodule(33%,4/12) than movable nodules(5.8%,28/476). Rapid growing, vocal cord palsy,and lymphadenopathy among the medical history had higher relative risk to cancer (relative risk= 14, 4.8, 10.2. respectively). We also examined 67 cases which were diagnosed by histology after operation and, through comparison between the results of histology and cytology., evaluated the effectiveness of fine-needle aspiration cytology. Sensitivity, specificity, false negative rate, and false positive rate of fine-needle aspiration cytology were 92-100%, 47-63%, 0-20%, 0-50%,respectively. Our data suggests that thyroid nodules of the patients which are characterized firm, fixed, rapid growing, lymphadenopathy, and vocal cord palsy require more careful evaluation for thyroid cancer. We also recommand thyroid aspiration cytology in first step evaluation to rule out thyroid cancer.

보강재 길이에 따른 보강토 옹벽의 지진저항 특성 연구

채영수, 윤원섭 水原大學校 2012 論文集 Vol.26 No.-

ABSTRACT In order to understand evaluation of the seismic stability of a reinforced earth retaining, we made chambers of 1:10 (the ratio of the miniature), considering the law of similarity based on drawings of representative cross sections. And we measured an increase in acceleration, earth pressure, and displacement after applying Hachinohe wave(long period), Ofunato wave(short period), and artificial wave, complying with the domestic standards, in order to evaluate the external stability of a reinforced earth retaining wall during earthquake based on the measurements. As a result, a unreinforced earth retaining wall collapsed at 2g of seismic acceleration. But a reinforced earth retaining wall was evaluated to ensure proper stability as well, with respect to the earth pressure gauge, the increments of earth pressure tend to be raised significantly in the upper than the lower and found that the longer reinforcement length, the displacement of reinforcement earth retaining walls was decreased and the earth pressure was increased. 본 연구에서는 보강토 옹벽 구조물의 지진저항 특성을 파악하기 위하여 대표단면을 기초로 하여 축소모형의 비율에 해당하는 상사법칙을 고려하여 1:10의 상사비로 토조를 제작하였다. 그리고 국내 설계기준에 준하여 장주기인 Hachinohe파, 단주기인 Ofunato파, 인공지진파를 가진하여 실험 대상단면에 대해 가속도변화, 토압, 변위를 측정하고, 측정된 결과를 통하여 보강토 옹벽의 지진 시 외적안정성을 평가하였다. 실험결과 보강재를 설치하지 않은 옹벽구조물에서는 지진가속도 0.2g에서 붕괴되었으나 보강재를 설치한 보강토 옹벽에서는 안정성을 확보하는 것으로 평가되었다. 토압계 측정결과 하부보다 상부에서 지진에 의한 토압의 증가량이 크게 발생되었으며, 보강재 길이가 증가할수록 보강토 옹벽의 변위는 저감되고, 토압은 증가되는 결과를 보였다.

야간 환자 발생양상에 관한 조사연구

원광연,심운택,조영채 충남대학교 의과대학 지역사회의학연구소 1988 충남의대잡지 Vol.15 No.2

This study was conducted with 800 patients, who came to the emergency rooms of hospital and clinic at night time of Cheongju medical bloc, to look for the characteristics of the occurance of: emergency patients at night time, for randomly sampled 7 days containing each different day from April 1st. to April 30th. 1987 on the basis of such various factors as age, sex, residence and status of patients. The following conclusions were obtained 1. The percentage of emergency patients by sex were 60.1% in male and 33.9% in female, making the ratio 1.54 : 1. The age group of 10s and 20s occupied 40.3% of all patients. 2. The percentage of each disease was 41.1% in injury and poisoning, 17.2% in disease of the respiratory system, 16.1% in disease of the digestive system. 3. Male had a higher incidence in the injury and poisoning, disease of the respiratory system, infectious and parasitic disease, but disease of the digestive system, disease of the nervous system and sense organ, complication of pregmancy, child birth and the p lerperium were higher in female. 4. Age distribution of emergency patients showed as followes : Injury and )oisoning had a higher percentage in the age group of 10-49 years, disease of respiratory system under 1 years of age, disease of the digestive system over 30 years of age, disease of circulartory system in 40-50 years of age. 5. Disease distribution on residential area revealed that residents out of city had higher propor tion of injury and poisoning, infectious and parasitic disease than the ones in city. The time of staying in the emergency room were less than 1 hour in 69% of all patients. 6. The status of patients when leaving the emergency room were complete cure(68.7%), admission(17.9%) self-discharge (12.5%), and death(0.9%).

수면 무호흡과 불안장애의 불면증에 대한 다원수면기록

채정호,박원명,채영래,김제헌 大韓神經精神醫學會 1994 신경정신의학 Vol.33 No.2

Objects : The authors studied polysomnographic findings of patients with sleep apnea DIMS (disorders of initiating and maintainig sleep) syndrome and anxiety disorders with insomnia related to another mental disorders. Methods : Eight patients with sleep apnea DIMS syndrome and fourteen patients with anxiety disorder with insomnia related to another mental disorder(nonorganic) were studied using computerized polysomnography. Results : 1) The sleep period time were significantly decreased in anxiety disorder group and the sleep latency was prolonged in these patients. 2) The changes in sleep stage and the number of arousals during sleep period time were more frequent in sleep apneic patients group. And using these variables we could discriminate sleep apneic patients group from subjects with anxiety disorder. 3) The stage 1 sleep was significantly increased in sleep apneic patients. 4) The apnea index in sleep apnea patients was 28.1±25.7. Conclusion : These results suggested that even though there were similiar clinical presentaion such as insomnia, the sleep features of sleep apnea DIMS syndrome and anxiety disorder with insomnia were different. And though there were no instruments to check respiratory flow or movement, it would be possible to discriminate the sleep apnea DIMS syndrome from the anxiety disorder with insomnia by recording the changes in sleep stage and the number of arousals in overnight electroencephalographic procedure.

중년여성의 연령별 체력 비교

원영두,송채훈,안용덕 朝鮮大學校 스포츠科學硏究所 2005 스포츠科學硏究 Vol.16 No.-

This study measured physical fitness with 282 middle-aged women between 30 and 59, living in G metropolitan city who have no abnormality as a result of physical examination with a view to develop standardization method of health and strength factors by age and model of converting such factors into health age measures and obtained the following conclusions. In comparison of physical fitness by age. there were statistically significant differences in grip strength, sit-up, side step, reaction time. trunk extension, sargent jump. close eyes foot balance, Vo2max, and subjects in their thirties showed higher scores in physical fitness measurement and the older they are, the lower their strength.

企業社會會計의 測定對象과 方法에 관한 硏究

蔡源榮 단국대학교 대학원 1984 學術論叢 Vol.8 No.-

A business enterprise has performed it essential social function of production and distribution of goods and services, which is also social responsibility. But these production­related activities of a business enterprise often do harm and provide benefit to other components of society in general. The modern business enterprise should assume the responsibility for such outgrowth brought about by the activities. The former is called corporate economic responsibility to society and the latter social but non­economic one. Corporate social accounting started from the demand for social information that will help to define and moniter the corporate social responsibility. It will also provide a basis for the development and application of better methods of evaluating and controlling corporate activities. This study discusses from the view­point of corporate social accounting that is a new field in the modern accounting, the essenoes of corporate social accounting and the objects of measurement and, the measurement and reporting problem of social responsibility that is the most difficult area in realizing corporate social accounting. This study is organized into five major chapters; (1) Introduction (2) Objects of measurement of corporate social accounting (3) Measurement methods of social coast and benefits. (4) Case application (5) Conclusion Though we have considerable difficults for the application of corporate social accounting theory to the corporation, I suggest for the future research in corporate social accounting as follows; (1) The definite identification and classification of the components of corporate social responsibility. (2) Development and validation of the new measurement methods. (3) Development of a system approach to indirect effects of corporate activities. (4) Development of the standardized and applicable model for corporate social reporting. (5) Verification and attestation of information provided by corporate social accounting.