폐포 대식세포 및 단핵구가 Interleukin-2 Enhanced Natural Killer 및 LAK Activity에 미치는 영향

조철호 ( Jo Cheol Ho ),김병일 ( Kim Byeong Il ),김세규 ( Kim Se Gyu ),천선희 ( Cheon Seon Hui ),김형중 ( Kim Hyeong Jung ),장준 ( Jang Jun ),안철민 ( An Cheol Min ),김성규 ( Kim Seong Gyu ),이원영 ( Lee Won Yeong ),윤정구 ( Yun J 대한내과학회 1992 대한내과학회지 Vol.42 No.5

저자들은 폐포 대식세포 및 말초혈액내의 단핵구가 NK 활성도 및 LAK 활성도에 미치는 영향을 보기위하여, 임파구에 여러 가지 농도(0, 100 : 1, 10 : 1, 1 : 1)의 폐포 대식세포와 단핵구를 넣어 IL-2 enhanced NK 활성도 및 LAK 활성도를 비교하여 다음과 같은 결과를 얻었다. 1) 여러 가지 농도의 단해구는 IL-2 enchanced NK 활성도 및 LAK 활성도에 영향을 미치지 않았다. 2) 동량의 페포대식세포(임파구 : 폐포 대식세포= 1 : 1)는 IL-2 enhanced NK 활성도를 의의있게 억제하였으나(p<0.05), 소량의 폐포대식세포(임파구 : 폐포 대식세포-10 : 1과 100 : 1)는 IL-2 enhanced NK 활성도를 억제하지 못하였다. 3) 임팍와 폐포 대식세포의 비율이 1 : 1과 10 : 1에서는 LAK 활성도를 의의있게 억제하였으나, 소량의 폐포대식세포(임파구 : 폐포 대식세포=100 : 1)는 LAK 활성도를 억제하지 못하였다(p<0.05). 이상의 결과로 IL-2 enhanced NK 활성도 및 LAK 활성도는 폐포 대식세포의 양에 비례하여 억제되었으나, 말초혈액내의 단핵구에 의해서는 영향받지 않는 것을 알 수 있었다. Alveolar macrophages (AM) are thought to function as primary effector cells against tumors growing in the lung. Systemic administration of lymphokine activated killer (LAK) cells and IL-2 resulted in partial antitumor response in patients with advanced cancer. LAK activity is influenced by various factors. We studied the effects of AM and blood monocytes from healthy donors on IL-2 enhanced NK activity against K-562 cells and LAK activity against Raji cells utilizing a 4h ^(51)Cr release assay. The following results were obtained: 1) The addition of different doses of human blood monocytes showed no suppression or enhancement of IL-2 enhanced NK and LAK activity. 2) The addition of high dose of AM (Lymphocyte: AM=1:1) significantly suppressed IL-2 enhanced NK activity. Smaller doses of AM (Lymphocyte: AM= 10:1and 100:1) did not suppress IL-2 enhanced NK activity. 3) The addition of high dose of AM (Lymphocyte: AM = 1:1 and 10:1) significantly suppressed LAK activity. The smallest dose of AM (Lymphocyte: AM= 100:1) did not suppress LAK activity. In conclusion, IL-2 enhanced NK and LAK activity were dose-dependently suppressed by human alveolar macrophages. However IL-2 enhanced NK and LAK activity were not suppressed by blood monocytes.

한국에서 동물간호사제도의 필요성과 자격시험에 대한 분석 및 평가

이성호,박영석,박병권,곽명순,강종일,조성진,김선균,김병수 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

The study examined qualification test of the 1st term Animal Nurse Technician and conducted questionnaire survey as well as site investigation to settle Animal Nurse Technician system in Korea. The objects were undergraduates, graduates and director of animal hospital. 115 applicants applied to the qualification test of animal specialists, and 50 applicants passed the test to record 43.47% of ratio of successful applicants. The subjects having relative difficulty were anatomy physiology and public hygiene to record 19 points in average: In particular, the anatomy physiology recorded 35 points of the highest score and 6 points of the lowest score to have the highest deviation and to require adjustment of difficulties. 89.2% of the interviewee supported needs of animal nurse technician system in Korea to show positive response. At the survey of actual conditions of recruitment of animal nurse technicians at animal hospitals, 28.6% of the interviewee was employing the technicians, and 35.7% had employment plan, and 32.1% wanted to employ them under good conditions. In other words, 96 4% of the interviewee responded positively, while no more than 3.6% did negatively. In Korea, the animal nurse technicians had roles as follows: The animal hospitals gave priority to reception service and customer controls followed by medical examination support,whilethecollegesdidtomedicalexaminationsupport. To differentiate hospitals in accordance with the increase of number of animal hospitals, the animal hospitals should employ animal nurse technicians having specialty and qualifications on animal nurse technician examination. In particular, the roles and demand of animal nurse technicians were expected to grow because of developed technologies of veterinary medical science, development of medical supplies and instrument, and the increase of aged animals, etc. Therefore, job analysis on animal nurse technicians should be done to adjust the subjects of qualification test and to develop questions.

慶南 梁山地方의 工業化에 따른 氣溫上昇에 대한 考察

李富龍,田炳日,金有根 부산대학교 환경문제연구소 1991 環境硏究報 Vol.9 No.-

The temperature variations due to industrialization in Yangsan area are investigated using the 10 years(1980∼1989) temperature data and compared with those of Jinju. The major results are as follows: (1) The rates of increase of mean and minimum temperatures were more pronounced in Yangsan area than in Jinju area, and the increasing rates were always positive for every month. (2) There exists close correlation between the growth of population and increase of minimum temperature, and between the growth of population and the increase of mean temperature. Furtheromore, close correlations between the increase of those temperature and other industrial factors are also indentified.

지구성 운동이 자연발생 고혈압 흰쥐의 혈압에 미치는 영향

이규승,전병화,김일곤,전종귀 忠南大學校體育科學硏究所 1996 體育科學硏究誌 Vol.14 No.1

The purpose of this study is to investigate the effects of indurance exercise on BP of SHR Experimental animals were SHR(180) and SD(90) and they were divided into three groups ; a experimental group1( practice group), a experiment group2(non practice group), and a comparative group (normal group). The experimental group 1 was practicing on a treadmill at 15m/min exercise intensity for 30 minutes a day four times per week for eight weeks. While raising experimental animals, We measured BP for each group once a week, and took the weight of the heart after killing a rat. and then we examined the concentration of ?? and ??, compared, and analyzed them. we have reached the following results. 1. As time passed, BP in the experimental group 1 was almost equal to BP eight weeks ago. BP in the experimental group 2 continued to rise and then showed typical hypertension. 2. The three groups were inclined to increase the weight of their hearts as time passed. However, the experimental group 2 presented the weight of hearts increasing compared with the experimental group1 after eight weeks. 3. In the experimental group 1, and experimental group 2 groups, ?? concentration was but ?? concentration increased as time passed. However, the experimental group1 showed fewer changes than the experimental group 2. 4. The weight of all three groups were inclined to increase as time passed, but it didn't present any noteworthy differences. According to the analysed result of the above experiment, endurannsce exercise becomes an important factor in preventing the raising of BP of SHR, and the hypertrophy of hearts. Key Words : Spontaneously Hypertension Rats, Blood Pressure, Endurance Ecercise

웹 브라우져를 통한 서버 클라이언트 환경의 영상처리 실습 시스템 설계

이병일,손병환,최항묵,최흥국 인제대학교 2001 仁濟論叢 Vol.16 No.1

웹 기반의 환경은 인터넷과 컴퓨터의 접목으로 실생활에서 연구활동에 이르기까지 다양하게 그 효용성의 범위를 굳혀가고 있다. 교육기관에서 활용하는 가상강좌는 이러한 웹의 장점을 활용한 학습방법의 다양화의 결과이다. 본 논문에서 설계한 웹 브라우져를 통한 서버 클라이언트 환경의 영상처리 실습 시스템은 가상강좌나 웹 환경이 구축된 장소에서 교육자와 피교육자사이의 교육효과를 증진시키도록 상호 의사전달의 효율성을 가지게 하는 시스템이다. 각 클라이언트가 다운로드 받은 컴포넌트를 실행하여 구동하게 되면 클라이언트들이 자신의 실습을 위한 프로그램을 로컬에서 가동할 수 있도록 하였기 때문에, 서버측의 부하가 얼어서,실습 결과영상을 로컬 클라이언트에서 부하시간 없이 얻을 수 있게 하였다. 또한 서버의 수정 혹은 갱신으로 바뀌어진 컴포넌트는 클라이언트 측에서 접속시 업데이트가 가능하므로 각 클라이언트에 대한 업 데이트를 따로 고려하지 않아도 되는 장점이 있다. 또한 컴포넌트가 가지는 여러 가지 메쏘드들은 다양한 영상처리의 결과를 볼 수 있게 해 줌으로써 고가의 소프트웨어를 따로 구입하지 않아도 되는 장점을 가지게 된다. The environment of web is applied variously from our life to research activities thanks to the internet and the computer. The virtual lecture utilized by an educational institution is the result of application of a learning system with the advantage of web. In this paper, a design of the image processing training system at the environment of server-client through web browser is the system of high degree of efficiency at the point of communication between lecturer and student. A client can get the result image from another client without load balancing of the server, because the processer for image processing is operated at the container of a client after downloaded as the form of a component. Clients can get the new version of component when they contact, so clients do not need to consider the status of updated component locating in the server. Furthermore, the client can handle an image with the many operations included in component with no purchase of the software additionally, that is another merits of this system.

태국 깐짜나부리지역의 다크투어리즘 역사경관 활용에 대한 연구 -콰이강의 헬파이어패스와 연합군 묘지를 중심으로-

오일환,윤병국,이준태 한국사진지리학회 2017 한국사진지리학회지 Vol.27 No.3

본 연구는 역사적 장소를 직접 방문하여 새로운 교훈을 얻는 다크투어리즘 관점에서 전쟁의 참상과 잔혹한 현장이었던 깐짜나부리지역을 중심으로 전쟁유산의 역사경관과 관광자원의 구성요소에 대하여 살펴보았다. 첫째, 태국은 고대 왕조의 역사도시 유적지 그리고 자연생태환경 원시림 등의 세계유산이 있다. 이와 함께 방콕의 왕궁유산을 중심으로 짜오프라야강의 근대 개항지를 재현하고 있으며 현지 주민의 운하생활 모습 그리고 해변을 활용한 휴양지 등이 주요한 관광자원이다. 둘째, 깐짜나부리는 제2차 세계대전 기간에 태국과 미얀마를 연결하는 죽음의 철도공사 지역으로 대표적인 다크투어리즘 장소이다. 연합군 포로들의 유품을 전시하는 제스전쟁박물관 그리고 철도공사강제노역장소인 헬파이어패스와 이를 추모하는 기념박물관을 비롯하여 연합군 포로 희생자 묘역인 던락묘지와 청까이묘지 등이 있다. 셋째, 이러한 역사문화도시와 자연환경유산은 콰이강의 다리라는 영화적 유희요소 뿐 아니라 죽음의 철도와 연합군 묘지의 서사적 스토리텔링을 전쟁유산과 태국고유의 관광자원과 결합하여 관광상품으로 활용하고 있다. 그리고 세계 여러 국가 명칭을 도로이름으로 활용하고 빛과 소리 축제와 결합하면서 국제적인 다크투어리즘 유산으로 확장하고 있다. The purpose of this study is to examine components of tourism and recreation that which use of war heritage that are scattered in the Kanchanaburi region as new tourist attractions. It may have been a tragic place of many wars. However, as dark tourism attractions, it can attract much interest as a new learning tour to visit these historical places. First, Thailand’s World Heritage Site actively utilizes archaeological remains of historical city ruins of ancient dynasties and the natural ecological environment of primeval forest as tourism resources. Second, the Kanchanaburi region uses the war heritage of the Death Railway, which connects the Thai and Myanmar(Burma) during the Second World War, as dark tourism. The Jeath War Museum, which displays and reproduces the lifestyle and relics of Allied prisoners, and the Hellfire Pass and Museum with the name of Hellfire as a torch work, as well as the Kanchanaburi War Cemetery and the Chung Kai War Cemetery. Third, these war heritage combines the light and sound festival with commercialization of the film factor of the bridge of the River Kwai and the railroad of death. In addition, the names of cities in the world are given as the names of roads in the city, and waterfalls of national parks and the natural ecological environment are merged and utilized as international dark tourism elements.

베트남 다크투어리즘 유산의 현황과 활용에 관한 연구

오일환,윤병국,이준태 한국사진지리학회 2017 한국사진지리학회지 Vol.27 No.2

본 논문은 베트남 다크투어리즘 유산의 현황과 활용에 관한 연구를 목적으로 호치민 중심의 남부권역에 대한 전쟁유산의 구성요소와 양상을 고찰하였다. 베트남 다크투어리즘의 전쟁유산으로 하노이 중심의 북부지역은 전쟁의 승자와 패배자의 정치적 개념으로 상징화하면서 자연유산과 결합하고 있다. 중부지역은 후에, 미선 그리고 호이안의 전통문화유산과 DMZ지역의 전쟁유산을 접목하면서 다낭해변의 관광요소를 활용하고 있다. 호치민시를 중심으로 한 남부권역은 프랑스와의 독립항전과 미국에 대한 반전유적지 그리고 혁명유적지로서의 전쟁유산뿐 아니라 맹그로브 숲과 해변휴양관광을 결합하면서 메콩델타지역의 정치 경제적 중심공간으로 상징화하고 있다. 베트남 다크투어리즘의 전쟁유산은 역사 문화적 지역성이 투영된 장소적 진정성과 전쟁유산을 재현하고 기억하는 공간의 기념성을 융합하면서 중요한 관광요소로 활용하고 있다. 이와 함께 외세에 대한 저항정신과 항전으로 쟁취한 독립에 대한 자부심과 애국심을 확립하는 정신적 가치의 전쟁유산으로 활용하고 있다. The purpose of this study is to investigate the components and aspects of war heritage in the southern part of Vietnam, focusing on the present situation and usage of Vietnam`s Dark Tourism. In the northen region, the war heritage of Vietnam Dark Tourism is combined with the natural heritage symbolizing the political concepts of the winner and loser of the war. The central region uses coastal tourism elements with the traditional historical culture of the dynasty and the war heritage in the DMZ area. The southern region around Ho Chi Minh is represented as the united central space of the Mekong Delta, integrating the mangrove forest with the beach recreational tourism as well as the war heritage and anti-war relics as a revolutionary site that was against France for independence and against America by Vietnam war. Vietnam`s Dark tourism is an important tourism resource since it combines the regional authenticity of the historical and cultural aspects with the spatial memorial that recreates and reminds the war heritage. It is also used as a patriotic tourism resource that establishes self-esteem and nationalism for the independence against foreign countries by physical and spiritual resistance.

영한/한영사전을 이용한 동의어/유의어 사전 자동 구축

고병일,이태우,서영훈 충북대학교 컴퓨터정보통신 연구소 2004 컴퓨터정보통신연구 Vol.12 No.1

본 논문에서는 한-영사전과 영-한사전의 상호 정보를 이용한 동의어/유의어사전 자동구축에 대해서 기술한다. 유의어/동의어사전은 정보검색분야 뿐만 아니라 의미정보를 요구하는 자연언어처리의 다양한 분야에서 필요로 한다. 기 구축된 한-영사전과 영-한사전 정보들을 이용하여 동의어/유의어 후보목록들을 획득하고, 획득된 후보목록들에 대해서 후보목록에 출현하는 빈도수, 사전의 위치정보, 입력명사정보들을 이용하여 최종적으로 동의어/유의어 목록들을 추출하게 된다. 동의어/유의어 사전 엔트리들은 한-영사전에 수록된 한국어 명사 64,630개를 대상으로 하여 구하였다. 제안한 동의어/유의어사전을 문서 필터링시스템에 적용하여 실험한 결과 종래방식보다 F-score가 약 0.01정도 상승되었다. This paper describes an automatic synonym-dictionary construction method using the mutual information from the Korean-English and English-Korean dictionaries. The synonym-dictionary is an important resource in the information retrieval and the various fields of the natural language processing requiring the semantic knowledge. Synonym candidate list is extracted by the information of pre-existing Korean-English and English-Korean dictionaries. Finally, synonym words are selected from the candidate-list, using its frequency in the candidates-list, the location information in the dictionary, and the given words. the synonym dictionary was constructed from the 64,630 Korean nouns which listed in the Korean-English dictionary. Document-Filtering System with this dictionary shows higher F-score than without it.

전북 익산지역에서의 묘화 이용실태 조사

박윤점,이일병,정주연,장흥기,허북구 한국식물인간환경학회 2001 인간식물환경학회지 Vol.4 No.1

This study was surveyed to know utilization of the in graveyard the military and the police(MP), the catholic graveyard(CG) and graveyard of mausoleum(GM). The items of investigation were the ratio, kinds of flower, color of cut flower and form of offering a bunch of flowers. The time of investigation were New Year's day, Chusok(the korean thanksgiving day) and a weekday. On a week day, the ratio of offering a bunch of flowers was 6.3 perrcent in GM. CG and GM were 2 and 6 percent, respectively, On Chusok MP was 9 percent, CG was 25 percent and GM was 55.9 percent. On New Year's Day MP was 17.9 percent, CG was 43.3 percent and GM was 49.8 percent. Except for GM, when we compared the chusok with a week day, they were offered 12-24 times. Of the kinds of cut flower offered a bunch of flowers, chrysanthemum was 60 percent or more without regard to MP, CG and GM. About color of cut flower, white was 39.2 percent or more and yellow was 8.8 percent or more. Most of used colors were white and yellow. And they were 48 percent or more. That of on a week day was low remarkably. The form of offered flower on a graveyard were various: a flower, a basket of flower, a potflower, a flower in a case of glass, and a flower in a vase. Of that, a bunch of flowers were 33 percent or more in GC, MP and CG. KEY WORDS : flower, graveyard, new year's day, chusok, chrysanthemum

동결건조 장미의 화색과 형태적 특성

서춘순,박윤점,이일병,허북구 한국화훼연구회 2001 화훼연구 Vol.9 No.2

Rosa hybrida L. 'Sandra' was freeze dried and investigated the length fur drying, color change of petal, leaf and stem, and the change of flower diameter, 12 days were needed to dry flower completely by natural drying method, otherwise 2 days needed by freeze drying. There was significant difference between fresh flower and natural dried flower in terms of L, a, b value of petal color, otherwise there was no significant difference between fresh flower and freeze-dried flower. L, a and b value of leaf and stem of freeze-dried flower was different comparing with those of fresh flower, however the degree of difference was not higher than these of natural-dried flower, There was no significant difference between fresh flower and freeze-dried flower in terms of anthocyanin content in petal. The change of flower diameter of natural-dried flower and freeze-dried flower comparing with fresh flower was respectively 52.0% and 9.9%.