한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

표면중합을 이용한 초발수 복합입자의 제조 및 표면특성 : 중합시간의 영향 The Effect of Polymerization Time

범정철,하종욱,박인준,김정훈,이수복,ShiYuan, Cheng 한국공업화학회 2003 응용화학 Vol.7 No.2

This study investigates the preparation of poly(perfluoroalkyl acrylate)[PTA]/silica composite particles by surface polymerization and their characteristics according to surface polymerization time. The particles were prepared by "grafting-from" technique by immobilizing self-assembled initiator and surface radical polymerization from silica particle surface. Characterization was done by contact angle and sliding angle measurements, surface roughness measurement and surface free energy estimation Contact angle were inversely proportion to sliding angle. Graft density(GD) and contact angle of composites increased according to polymerization time. On the other hand, surface free energy and sliding angle were decreased according to increment of polymerization time.

인지된 신뢰, 위험, 유용성 및 편의성이 전자정부 민원서비스 사용의도에 미치는 영향 : 온라인 민원 안내와 민원 신청 서비스를 중심으로

김범수,이정,김경규 한국정보사회진흥원 2006 정보화정책 Vol.13 No.4

전자정부 민원서비스 혁신 시스템(G4C) 사업을 추진한 대한민국 정부는 현재 4,700 여종의 정보와 서비스를 통합전자민원창구(www.egov.go.kr)를 통하여 제공하고 있다. 이러한 전자정부 대국민 민원서비스를 그 관여도에 따라 단순 정보 제공 등“민원 안내 서비스”와 인터넷을 통한“온라인 민원 신청 및 발급 서비스”등의 두 가지로 크게 분류하고, 각 서비스 별로 정부에 대한 신뢰, 정부 서비스 이용과정에서 인지된 위험, 편의성, 유용성이 전자정부 민원서비스 혁신시스템(G4C)의 사용의도에 미치는 영향을 연구하였다. 인터넷을 사용하는 성인 3,074명을 대상으로 한 설문 조사를 통하여 (1) 관여도가 높은 전자정부 서비스에서만, 정부에 대한 신뢰가 사용의도에 영향을 미치며, (2) 인지된 위험은 서비스 종류에 따라 다양한 수준의 영향력을 보이고, (3) 서비스 이용 의도에 가장 큰 영향을 미치는 변수는 유용성이며, (4) 편의성은 서비스 이용의도에 직접적인 영향을 미치기보다는 유용성을 매개로 하여 간접적으로 미치는 영향이 더 큼을 보였다.

뇌기능 장애 환자에서 뇌 SPECT의 유용성

김권영,신수범 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

Objective: To evaluate usefulness of the brain SPECT in brain dysfunction patients who showed low Mini-MentaI State Examination(MMSE) score. Method: Eighty four patients who were visited to a rehabilitation hospital for their brain dysfunction were retropectively studied. We investigated percent of positive finding in brain SPECT, brain CT, MRI, P-300 studies, and correlation of MMSE scores, brain SPECT, P-300 studies, and correlation of brain SPECT, brain CT and MRI, P-300 studies. Resutts: Percent of positive finding in brain SPECT was high than brain CT, MRI, P-300 studies. MMSE scores were positive correlation with brain SPECT, but no correlation with P-300 study(P>0.05). Brain SPECT were significant correlation with brain CT (P<0.05), but no correlation with brain MRI and P-300 studies (P>0.05). P-300 study was no correlation with brain CT, MRI (P>0.05). Conclusion: We concluded that brain SPECT is useful for reflection of brain dysfunction.

재조합 대장균에 의한 Poly(3-hydroxybutyric acid)의 생산

김범수 建陽大學校 1994 建陽論叢 Vol.- No.3

A recombinant Escherichia coil strain XLI-Blue (KS) harboring the poly(3-hydroxybutyric acid) [P(3HB)] biosynthesis genes from Alcaligenes eutrophus was used to produce P(3HB) by pH-stat fed-batch culture in complex medium. Intial glucose concentration for optimal growth was found to be 20 g/L from a series of flask culture. A final P(3HB) concentration of 89 g/L could be obtained after 42 h of cultivation. The pH-stat fed-batch culture of recombinant E. coli K12 (pSYL 104) using defined medium was not suitable for efficient production of p(3HB) due to the formation of acetic acid. Exponential feeding fed-batch culture of E. coli K12 (pSYL 104) achieved high cell concentration (101 g/L) by controlling the specific growth rate as low as 0.1 h?. However, the P(3HB) content was very low because of the different conditions for cell growth and P(3HB) production.

키틴계 담체를 이용한 효율적인 효소고정화법 개발

김용범,강수정,한상문 서울산업대학교 산업대학원 1999 大學院論文集 Vol.6 No.-

본 연구에서는 키토산을 담체로하고 5가지 다른 방법에 의해 단백질 가수분해 효소인 trypsin을 선정하여 효율적인 효소고정화법을 개발하고자하였다. 비교한 효소고정화 방법으로, 먼저 가교제의 변화로서 glutaraldehyde와 hexamethylenediisocyanate를 비교였고, 다음으로 프로세스의 변화로서 ⅰ)chitosan bead에 효소를 흡착한 후 glutaraldehyde로 가교하는 방법, ⅱ)chitosan bead에 효소를 흡착한 후 hexamethylenediisocyanate로 가교하는 방법, ⅲ)chitosan과 효소를 혼합하여 bead화하고 glutaraldehyde로 가교하는 방법, ⅳ)chitosan bead를 glutaraldehyde로 1차 가교 하고 효소를 흡착한 후 다시 glutaraldehyde로 2차 가교하는 방법, ⅴ)chitosan bead에 효소 흡착 후 glutaraldehyde로 가교 처리하여 NaOH로 처리하는 방법등으로 비교하여 ⅲ>ⅴ>ⅳ>ⅰ>ⅱ 의 순으로 아미노산 생성효율을 확인하므로써 보다 효율 높은 효소고정화법을 모색하였다. 가교제의 종류에서는 glutaraldehyde가 더 유리하였고, 고정화 가교방법에서는 chitosan과 효소를 미리 혼합하여 bead화한 다음 가교한 것이 기타 다른 방법들에 비해서 고정화 효율이 가장 우수함을 확인하였다. More effective methods for immobilization of enzymes(trypsin) were examined with chitosan beads, through comparison of several different immobilization methods. The methods applied in this experiment are: Firstly with different crosslinking agents : glutaraldehyde and hexamethylenediisocyanate. Secondly with different processes: ⅰ) Adsorption of enzyme on the beads, then crosslinking with glutaraldehyde. ⅱ) Adsorption of enzyme on the beads, then crosslinking with hexamethylenediisocyanate. ⅲ) Mixing chitosan with enzyme, then beads formation followed by crosslinking with glutaraldehyde ⅳ) Treatment with glutaraldehyde, then enzyme adsorption on the beads followed by crosslinking with glutaraldehyde. ⅴ) Adsorption of enzyme on the beads and then crosslinking with glutaraldehyde followed by treatment with 0.01N-NaOH aq. solution The order of superiority is ⅲ>ⅴ>ⅳ>ⅱ>ⅰ described above. The efficiencies of hydrolysis of milk protein by the immobilized enzymes were estimated by spectrophotometry of amino acids produced through hydrolysis.

재조합 대장균의 고농도 유가식 배양에 의한 인체 Granulocyte-Colony Stimulating Factor 생산

김범수,유미진 建陽大學校 1999 建陽論叢 Vol.- No.7

Fed-batch fermentation of recombinant Escherichia coli harboring the gene encoding mature human granulocyte-colony stimulating factor (hG-CSF) fused to the gene for the pectate lyase B (pelB) signal peptide of Erwinia caratovora was performed. The fusion protein, pelB-hG-CSF, was produced at a concentration of ca. 1.7 g/L in an inclusion body form.

난치성 외측 상과명에서 포동당 용액과 자가혈 주사치료의 효과

김종규,김권영,신수범 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.1

Background and Objectives: To investigate the effect of hyperosmolar dextreose and autologous blood injection in the refractory lateral epicondylitis. Materials and Methods: The sunjects consisted of 39 patients suffering refractory lateral epicondylitis. All patients had failed previous nonsurgical treatments including all or combinations of physical therapy, splinting, nonsteroidal anti-inflammatory medication, and prior steroid injections, Sixteen subjects were injected with 15% dextrose solution under the extensor carpi radialis and tender points. Other subjects were injected with 2mL of autologus blood under same area. ResuKs: In the comparison of the VAS before and after treatment, Prolotherapy was 6.38 and 3.44, autologous blood injects was 6.12 and 2.54 respectively, which demonstrated statistically significant decrease..The effect of autologous blood injections was shown to be more effective than that of prolotherapy. Conclusion: After autologous blood injection therapy in whom nonsurgical modlalities had failed were relieved completely of pain even during strenuous activity. This study offers encouraging results of an alternative minimally invasive treatemnet that addresses the pathophysiology of latera epicondylitis that has failed traditional nonsurgical modalities.

광주·전남지역의 무역구조 분석

모수원,김창범 조선대학교 지역사회발전연구원 2001 地域發展硏究 Vol.6 No.1

철강제품과 반도체의 수출행태

모수원,김창범 국제무역학회 2003 국제무역연구 Vol.9 No.1

한국경제는 외환위기 이후 경제개방의 확대에 따라 대외여건의 변동에 상당히 취약한 면을 보이고 있으며, IT산업의 비중확대로 IT경기가 경제에 미치는 영향이 확대되어 IT품목의 수출회복 없이는 경기회복을 기대할 수 없는 실정이다. 그러나 최근 세계경기의 침체와 수요감소로 IT품목의 수출은 큰 폭으로 감소한 반면 비IT품목의 수출은 상대적으로 양호하여 역양극화가 이루어지고 있다. 이에 따라 본고는 반도체와 철강제품의 수출구조를 분석하여, IT제품의 수출이 세계경기와 환율변동에 대해 장기에 걸쳐 더 큰 영향을 받으며, 특히 세계경기변동에 민감하게 반응한다는 점을 보인다. 또한 세계시장에서 공급과잉과 같은 불균형 요인에 대해 우리나라 IT산업의 적응능력이 상당히 낮다는 점도 밝힌다. The purpose of this study is to estimate and analyse the export structure of IT and non-IT products. We employ Engle and Granger two-step cointegration technique, Johansen's multivariate cointegration methodology and GPH test, since the model must be stationary to avoid the spurious results. The empirical results show that our model is stationary as well as mean-reverting. This paper also applies variance decompositions and impulse-response functions to get additional information regarding the responses of the export volumes of IT and Nor-IT products to the shocks in world business and real effective exchange rate. The results indicate that while both IT and non- IT products respond positively to the shocks and then decay very slowly, the responses of the former last longer and greater than those of the latter.