A Study of Suppliers' Participation in Private Exchanges: Focusing on MRO Markets

임성배(Seong-bae Lim),김성관(Sung-kwan Kim),Robert B. Mitchell,홍순구(Soongoo Hong) 한국전자거래학회 2004 한국전자거래학회지 Vol.9 No.4

성장 잠재력에도 불구하고 많은 B2B 시장은 참여업체 수의 부족으로 운영의 어려움을 겪고 있다. 따라서 어떠한 방법을 통해 충분한 숫자의 기업들을 시장에 참여하도록 유도할 것인가가 B2B 시장의 성공을 위한 주요 요인 중의 하나로 인식되고 있다. 본 논문은 MRO 시장을 대상으로 공급업체들을 구매자 중심의 전용시장(Private Exchanges)에 참여하게 만드는 요인들이 어떤 것인지를 규명해 보는 것을 주요 목적으로 하고 있다. 이를 위해 EDI 채택에 관한 선행연구와 실무자들과의 면접에 기초하여 실험대상 요인들을 추출하였다. 불완전한 계약 이론(Incomplete contract theory)에 기초하여 가설의 설정과 검증을 하였으며, 분석 결과 시장에 참여할 것으로 기대되는 공급업자들의 수와 시장 참여의 대가로 주어질 보상의 유무가 B2B시장의 참여에 긍정적인 영향을 주는 요인으로 나타났다. 한편 구매업자에 대한 신뢰는 유의한 요인으로 드러나지 않아 공급업자들은 기존의 구매업자와의 신뢰관계가 B2B 시장에서는 중요하지 않는 것으로 조사되었다. Many B2B electronic markets (EMs) are struggling to survive because they failed to attract enough participants. Thus reaching critical mass of participants is one of the key success factors for various types of EMs. The main purpose of this study is to investigate factors that lead MRO (maintenance, repair, and operating) suppliers to participate in private exchanges (PE), the buy-side EM. This paper introduces the characteristics of the PE according to the classification schemes introduced in previous studies about EM types. Literature is reviewed on suppliers’ adoption of inter-organizational information systems focusing on EDI adoptions issues. Data analysis based on incomplete contract theory and the social exchange theory is then presented. The results of this study show that the number of suppliers and subsidy are factors that influence suppliers' participation in PEs. Nonsignificant results relating to trust imply that suppliers who are invited to participate in a PE do not expect their off-line relationships with the buyer to be transferred to the PE.

Comparison of 90‐day case‐fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis

Yu, K‐,H.,Hong, K‐,S.,Lee, B‐,C.,Oh, M‐,S.,Cho, Y‐,J.,Koo, J‐,S.,Park, J‐,M.,Bae, H‐,J.,Han, M‐,K.,Ju, Y‐,S.,Kang, D‐,W.,Appelros, P. Blackwell Publishing Ltd 2011 Acta neurologica Scandinavica Vol.123 No.5

<P>Yu K‐H, Hong K‐S, Lee B‐C, Oh M‐S, Cho Y‐J, Koo J‐S, Park J‐M, Bae H‐J, Han M‐K, Ju Y‐S, Kang D‐W, Appelros P, Norrving B, Terent A. Comparison of 90‐day case‐fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis. 
Acta Neurol Scand: 2011: 123: 325–331. 
© 2010 John Wiley & Sons A/S.</P><P><B>Background – </B> It has not been clarified whether the disparity in ischemic stroke outcome between populations is caused by ethnic and geographic differences or by variations in case mix. Propensity score matching (PSM) analysis can overcome some analytical problems but is rarely used in stroke outcome research. This study was to compare the ischemic stroke case‐fatality between two PSM cohorts of Sweden and Korea.</P><P><B>Methods – </B> Prognostic variables related to baseline characteristics and stroke care were included in our PSM model. Then, we selected 7675 Swedish and 1220 Korean patients with ischemic stroke from each stroke registers and performed one‐to‐one matching based on propensity scores of each patient.</P><P><B>Results – </B> After PSM, all measured variables were well balanced in 1163 matched subjects, and the 90‐day case‐fatality was identical 6.2% (HR 0.997, 95%CI 0.905–1.099) in Sweden and Korea.</P><P><B>Conclusions – </B> No difference is found in the 90‐day case‐fatality in propensity score‐matched Swedish and Korean patients with ischemic stroke.</P>

Combinatorial Influence of Bimodal Size of B2 TiCu Compounds on Plasticity of Ti-Cu-Ni-Zr-Sn-Si Bulk Metallic Glass Composites

Hong, S. H.,Kim, J. T.,Lee, M. W.,Park, J. M.,Lee, M. H.,Kim, B. S.,Park, J. Y.,Seo, Y.,Suh, J. Y.,Yu, P. Springer Science + Business Media 2014 Metallurgical and Materials Transactions A - Physi Vol.45 No.5

<P>We report on the formation of Ti-Cu-Ni-Zr-Sn-Si bulk metallic glass composites containing bimodal size of B2 TiCu compounds. The small B2 TiCu compound with a size of 1 to 10 mu m has a strong influence on the oscillation of the shear stress, thus causing wavy propagation of the shear bands. In contrast, the large B2 TiCu compound with a size of 70 to 150 mu m dissipates the shear stress by branching and multiplication of the shear bands. By forming the bimodal size of B2 TiCu compound, it is possible to determine the harmonic influence to further enhance the plasticity of the Ti-Cu-Ni-Zr-Sn-Si bulk metallic glass composites.</P>

Influence of spherical particles and interfacial stress distribution on viscous flow behavior of Ti@?Cu@?Ni@?Zr@?Sn bulk metallic glass composites

Hong, S.H.,Kim, J.T.,Mun, S.C.,Kim, Y.S.,Park, H.J.,Na, Y.S.,Lim, K.R.,Park, J.M.,Kim, K.B. Elsevier Applied Science 2017 INTERMETALLICS Vol.91 No.-

Bulk metallic glass composites containing micro-scale B2 particles are subject to investigation with regards to the influence of B2 particles and interfacial stress and strain distribution on the viscous flow behavior at a super-cooled liquid state. An increased volume fraction of B2 particles leads to an increase of minimum viscosity and influences viscous flow behavior before crystallization. In high temperature deformation, the bulk metallic glass shows homogeneous deformation feature. However, the heterogeneous deformation feature is found in thermoplastically deformed bulk metallic glass composite. The strong stain accumulation and sluggish viscous flow occur around B2 particles, which are caused by the heterogeneous stress distribution linked to stress concentration and shear stress impediment around B2 particles. The sluggish viscous flow of super-cooled liquids around B2 particles during high temperature deformation induces an increase of viscosity and strongly affects the viscous flow behavior of Ti-based bulk metallic glass composites containing micro-scale spherical B2 particles.

혈청 HBV bDNA 음성이나 간기능검사 이상을 보인 만성 B형 간염 환자들의 임상상

김상진 ( S. J. Kim ),박중원 ( J. Park ),김진희 ( J. H. Kim ),홍요한 ( Y. H. Hong ),정혜령 ( H. R. Jung ),김형준 ( H. J. Kim ),도재혁 ( J. H. Do ),유병철 ( B. C. Yoo ),박실무 ( S. M. Park ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-

<목적> B형 간염바이러스(HBV)의 증식이 억제되면 만성 B형 간염의 활동성은 감소되며 이러한 이유에서 라미뷰딘과 같은 항바이러스제들을 치료제로 사용하고 있다. 그러나 HBV의 혈중 농도는 낮으나 간기능검사 이상을 보이는 만성 B형 간염 환자들이 상당수 있어 그 원인 규명이 필요한 실정이다. 이에 연구자들은 혈청 HBV branched DNA(bDNA) 음성인 만성 B형 간염 환자들을 대상으로 간 기능검사 이상과 관련될 수 있는 임상적 원인들을 조사하

Inhibitory effect of obovatol on nitric oxide production and activation of NF-κB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells

Choi, M.S.,Lee, S.H.,Cho, H.S.,Kim, Y.,Yun, Y.P.,Jung, H.Y.,Jung, J.K.,Lee, B.C.,Pyo, H.B.,Hong, J.T. North-Holland ; Elsevier Science Ltd 2007 european journal of pharmacology Vol.556 No.1

The components of Magnolia obovata are known to have many pharmacological activities. In this study, we investigated the effects of obovatol, a neolignan compound isolated from the leaves of M. obovata, on nitric oxide (NO) production and NF-κB activity in lipopolysaccharide (LPS)-activated RAW 264.7 cells. The results show that obovatol (1-5 μM) significantly inhibited LPS-induced NO production in a concentration-dependent manner (IC<SUB>50</SUB>: 0.91 μM). Consistent with the inhibitory effect on NO production, obovatol inhibits the expression of inducible nitric oxide synthase and cyclooxygenase-2 expression. Furthermore, obovatol suppressed NF-κB (p50 and p65) translocation to the nucleus as well as IκB release resulting in the inhibition of the DNA binding activity of the NF-κB. Obovatol also inhibited c-Jun N-terminal kinase (JNK) and extracellular signal-regulated kinase (ERK) signal, which are the most significantly involved signal in NO production and NF-κB activation. When the cells were treated with the combination of obovatol with U0126 (an ERK inhibitor) or SP600125 (a JNK inhibitor) as well as with SC-514 (an IKK2 inhibitor), much more inhibition of NO production was observed than that by obovatol alone. The present results suggest that obovatol has an inhibitory effect on NO production through the inhibition of NF-κB/MAPK activity, and thus can be used as an anti-inflammatory agent.

Peroxiredoxin 6 expression is inversely correlated with nuclear factor-κB activation during Clonorchis sinensis infestation

Pak, J.H.,Son, W.C.,Seo, S.B.,Hong, S.J.,Sohn, W.M.,Na, B.K.,Kim, T.S. Pergamon ; Elsevier Science Ltd 2016 FREE RADICAL BIOLOGY AND MEDICINE Vol.99 No.-

Clonorchis sinensis is a carcinogenic human liver fluke. Its infection promotes persistent oxidative stress and chronic inflammation environments in the bile duct and surrounding liver tissues owing to direct contact with worms and their excretory-secretory products (ESPs), provoking epithelial hyperplasia, periductal fibrosis, and cholangiocarcinogenesis. We examined the reciprocal regulation of two ESP-induced redox-active proteins, NF-κB and peroxiredoxin 6 (Prdx6), during C. sinensis infection. Prdx6 overexpression suppressed intracellular free-radical generation by inhibiting NADPH oxidase2 and inducible nitric oxide synthase activation in the ESP-treated cholangiocarcinoma cells, substantially attenuating NF-κB-mediated inflammation. NF-κB overexpression decreased Prdx6 transcription levels by binding to two κB sites within the promoter. This transcriptional repression was compensated for by other ESP-induced redox-active transcription factors, including erythroid 2-related factor 2 (Nrf2), hypoxia inducible factor 1α (HIF1α), and CCAAT/enhancer-binding protein β (C/EBPβ). Distribution of immunoreactive Prdx6 and NF-κB was distinct in the early stages of infection in mouse livers but shared concomitant localization in the later stages. The intensity and extent of their immunoreactive staining in infected mouse livers are proportional to lesion severity and infection duration. The constitutive elevations of Prdx6 and NF-κB during C. sinensis infection may be associated with more severe persistent hepatobiliary abnormalities mediated by clonorchiasis.

Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-κB

Lee, S.Y.,Yuk, D.Y.,Song, H.S.,Yoon, D.Y.,Jung, J.K.,Moon, D.C.,Lee, B.S.,Hong, J.T. North-Holland ; Elsevier Science Ltd 2008 european journal of pharmacology Vol.582 No.1

Biphenolic components in Magnolia obovata including magnolol and honokiol have shown several pharmacological activities such as anti-tumor, anti-oxidant and anti-inflammatory effects. Previously in cultured macrophage Raw264.7 cells and fibroblast, we found that obovatol, an active compound isolated from M. obovata inhibited NF-κB activity which has been known to be a significant transcriptional factor to control of cancer cell growth. We investigated here whether obovatol could inhibit NF-κB activity, and thereby inhibit cancer cell growth in prostate (LNCaP and PC-3) and colon cancer (SW620 and HCT116) cells. Treatment of obovatol (10, 15, 20, 25 μM) inhibits cancer cell growth in the absence or the presence of tumor necrosis factor-α (TNF-α , 10 ng/ml) and tetradecanoyl phorbol acetate (TPA 10 or 50 nM) in a concentration-dependent manner through induction of apoptotic cell death. Cytotoxic activity was not observed in normal cells with up to 50 μM obovatol. It was also found that obovatol inhibited TNF-α and TPA-induced transcriptional and DNA binding activities of NF-κB. In further study, obovatol decreased translocation p65 and p50 into nucleus via decrease of phosphorylation of IκB. Correlated well with the induction of apoptosis, obovatol increased the expression of the apoptotic genes; Bax, caspase-3, caspase-9, whereas inhibited expression of anti-apoptotic genes; Bcl-2, inhibitor of apoptosis protein (IAP-1) and X chromosome IAP (XIAP) as well as the cell proliferation marker genes; Cox-2, c-Fos, c-Jun and cyclin D1. These results suggest that obovatol inhibits prostate and colon cancer cell growth via induction of apoptotic cell death, and that inhibition of NF-κB may be a significant as its action mechanism.

Autotrophic hydrogen photoproduction by operation of carbon-concentrating mechanism in Chlamydomonas reinhardtii under sulfur deprivation condition

Hong, M.E.,Shin, Y.S.,Kim, B.W.,Sim, S.J. Elsevier Science Publishers 2016 Journal of biotechnology Vol.221 No.-

<P>Under autotrophic conditions, starch plays an important role in establishing anoxic conditions during PSII-dependent hydrogen (H-2) photoproduction in microalgae. This is because starch is the sole organic substrate during respiratory consumption of internal oxygen (O-2) from PSII-dependent direct pathway. Herein, we propose a novel approach to further facilitate the internal starch synthesis of Chlamydomonas reinhardtii through the operation of carbon-concentrating mechanism (CCM) along with a two-stage process based on sulfur (S) deprivation, thereby resulting in enhanced anaerobic capacity during PSII-dependent H-2 photoproduction. When CCM-induced cells were exposed to high levels of carbon dioxide (CO2) (5%, v/v) with S deprivation, internal levels of starch were significantly elevated by retaining a functional CCM with the boosted photosynthetic activity during 24 h of O-2 evolution phase (I) of S deprivation. Consequently, during H-2 production phase of S deprivation at irradiance of 50 mu E m(-2)s(-1), the concentrations of starch and H-2 in CCM-induced cells were remarkably enhanced by 65.0% and 218.9% compared to that of CCM-uninduced cells, respectively. The treatment of low-CO2-driven CCM induction prior to S deprivation is a cost-effective and energy-efficient strategy that significantly improves the solar-driven H-2 production by microalgae; this is particularly realizable in an industrial scale. (C) 2016 Elsevier B.V. All rights reserved.</P>

Three dimensional evaluation of aluminum plates with wall-thinning by full-field pulse-echo laser ultrasound

Hong, S.C.,Abetew, A.D.,Lee, J.R.,Ihn, J.B. Applied Science Publishers 2017 Optics and lasers in engineering Vol.99 No.-

We propose a full-field pulse-echo laser ultrasonic wave propagation imager (FF-PE-UPI) for the evaluation of structural defects. The FF-PE-UPI consists of a Q-switched laser for the generation of thermoelastic waves, a laser Doppler vibrometer (LDV) for sensing, and a two-axis translation stage for raster scanning of the combined generation and sensing laser beams. A-scan, B-scan, and C-scan data representations are used for the evaluation of structural defects. Three specimens were tested: a 4-mm aluminum plate with an area of 50% thickness reduction, a 6-mm aluminum plate with an area of 25% thickness reduction, and an 8-mm aluminum plate with engraved letters. The damages on the tested specimens were successfully visualized.