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      • The Role of Marketing Function in the New Product Development Process in the Hotel Industry

        Lee,Yeong Ah 한국복합리조트포럼 2022 관광체육연구 Vol.1 No.1

        Purpose: The purpose of this study was to investigate the role of marketing function in New Product Development(NPD) in the hotel industry. Method: In the research, using in-dept interviews with ten hotel managers and executives in the UK and South Korea, data were collected in the area of NPD. Results: Overall, this research found that categorization of new products in general in not fully applied to the hotel industry, due to their varied characteristics, including intangibility, heterogeneity, perishability and inseparability. However, the predevelopment stages was emphasized by the entire process and to a perversion of the concept of the product itself. In order to launch a new product successfully, the role of marketing is more than ever vital, leading activities in the commercialization. Conclusion: In conclusion, the results of this paper suggest that sophisticated market research is not performed as part of the process, but it is carried out throughout the process to monitoring market changes in the hotel industry. This study, furthermore, require into the specific NPD framework with a specific example of a new product in an organization, which would contribute to setting more systemic behavior for practitioners of NPD in hotels.

      • Quantitative Estimation of Fruit Crops Water Stress using Infrared Imaging

        ( Ah-yeong Lee ),( Suk-ju Hong ),( Yun-hyeok Han ),( Seok Kyu Yun ),( Minyoung Kim ),( Ghiseok Kim ) 한국농업기계학회 2018 한국농업기계학회 학술발표논문집 Vol.23 No.1

        In order to enhance the competitiveness of agriculture and develop into future growth industries, researches are being conducted to spread smart farm universally that combines ICT. Among them, research on Phenomics, which is a technology for developing plant phenotype that combines ICT, bio, and optical technology, is essential. Among the various phenotypes of crops, leaf temperature of crops provides important physiological information for crop management such as moisture content, water stress, and disease. By measuring changes in plant temperature due to the opening and closing of crop pores, the response of crops to various stresses can be analyzed. Infrared thermal imaging technique is non-destructive unlike conventional contact sensors because it does not contact with objects. It makes it possible to measure the temperature of the entire range of the leaves, thus enabling accurate and precise temperature measurement. In this study, leaf temperature information of crops is extracted by thermal images. Using the extracted temperature, we confirmed the changes of the leaf temperature with time and the relationship between the leaf temperature and the soil water potential. Peach crops are used. After different soil water potential treatments, the temperature, humidity, water tension, thermal imaging data were obtained. After obtaining the spatial information of the leaves using thermal images, the temperature information of the leaves of each tree was extracted through image processing. The relationship between water stress and leaf temperature was analyzed by checking the relationship between the leaf temperature and soil water potential.

      • SCIESCOPUS

        Effects of warming and eutrophication on coastal phytoplankton production

        Lee, Kyung Ha,Jeong, Hae Jin,Lee, Kitack,Franks, Peter J.S.,Seong, Kyeong Ah,Lee, Sung Yeon,Lee, Moo Joon,Hyeon Jang, Se,Potvin, Eric,Suk Lim, An,Yoon, Eun Young,Yoo, Yeong Du,Kang, Nam Seon,Kim, Kwan Elsevier Science B.V., Amsterdam. 2019 HARMFUL ALGAE Vol.81 No.-

        <P><B>Abstract</B></P> <P>Phytoplankton production in coastal waters influences seafood production and human health and can lead to harmful algal blooms. Water temperature and eutrophication are critical factors affecting phytoplankton production, although the combined effects of warming and nutrient changes on phytoplankton production in coastal waters are not well understood. To address this, phytoplankton production changes in natural waters were investigated using samples collected over eight months, and under 64 different initial conditions, established by combining four different water temperatures (i.e., ambient T, +2, +4, and + 6 °C), and two different nutrient conditions (i.e., non-enriched and enriched). Under the non-enriched conditions, the effect of warming on phytoplankton production was significantly positive in some months, significantly negative in others, or had no effect. However, under enriched conditions, warming affected phytoplankton production positively in all months except one, when the salinity was as low as 6.5. These results suggest that nutrient conditions can alter the effects of warming on phytoplankton production. Of several parameters, the ratio of initial nitrate concentration to chlorophyll <I>a</I> concentration [NCCA, μM (μg L<SUP>−1</SUP>)<SUP>−1</SUP>] was one of the most critical factors determining the directionality of the warming effects. In laboratory experiments, when NCCA in the ambient or nutrient-enriched waters was ≥1.2, warming increased or did not change phytoplankton production with one exception; however, when NCCA was <1.2, warming did not change or decreased production. In the time series data obtained from the coastal waters of four target countries, when NCCA was 1.5 or more, warming increased phytoplankton production, whereas when NCCA was lower than 1.5, warming lowered phytoplankton production, Thus, it is suggested that NCCA could be used as an index for predicting future phytoplankton production changes in coastal waters.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Four temperatures and two nutrient conditions in 8 months were combined. </LI> <LI> Under non-enriched conditions, warming affected positively, negatively, or negligibly. </LI> <LI> Under the enriched conditions, warming in all months except one affected positively. </LI> <LI> Thus, nutrient conditions can alter warming effects on phytoplankton production. </LI> <LI> Ratio of initial nitrate to chlorophyll-a concentration was a critical factor. </LI> </UL> </P>

      • SCISCIESCOPUS
      • Noncontrast Myocardial T1 Mapping by Cardiac Magnetic Resonance Predicts Outcome in Patients With Aortic Stenosis

        Lee, Heesun,Park, Jun-Bean,Yoon, Yeonyee E.,Park, Eun-Ah,Kim, Hyung-Kwan,Lee, Whal,Kim, Yong-Jin,Cho, Goo-Yeong,Sohn, Dae-Won,Greiser, Andreas,Lee, Seung-Pyo Elsevier Science B.V. Amsterdam 2018 JACC CARDIOVASCULAR IMAGING Vol.11 No.7

        <P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>The aim of this study was to evaluate whether native T1 value of the myocardium on cardiac magnetic resonance (CMR) could predict clinical events in patients with significant aortic stenosis (AS).</P> <P><B>Background</B></P> <P>Although previous studies have demonstrated the prognostic value of focal fibrosis using late gadolinium enhancement (LGE) by CMR in AS patients, the prognostic implication of diffuse myocardial fibrosis by noninvasive imaging remains unknown.</P> <P><B>Methods</B></P> <P>A prospective observational longitudinal study was performed in 127 consecutive patients with moderate or severe AS (68.8 ± 9.2 years of age, 49.6% male) and 33 age- and sex-matched controls who underwent 3-T CMR. The degree of diffuse myocardial fibrosis was assessed by noncontrast mapping of T1 relaxation time using modified Look-Locker inversion-recovery sequence, and the presence and extent of LGE were also evaluated. The AS patients were divided into 3 groups by the native T1 value. Primary endpoint was a composite of all-cause death and hospitalization for heart failure.</P> <P><B>Results</B></P> <P>Native T1 value was higher in AS patients, compared with control subjects (1,232 ± 53 ms vs. 1,185 ± 37 ms; p = 0.008). During follow-up (median 27.9 months), there were 24 clinical events including 9 deaths (6 pre-operative and 3 post-operative), the majority of which occurred in the patients in the highest T1 tertile group (2.4% vs. 11.6% vs. 42.9% for lowest, mid-, and highest tertile groups; p < 0.001 by log-rank test). The total number of events for both pre- and post-operative events also occurred more frequently in patients in the highest T1 tertile group. EuroSCORE II, the presence and/or extent of LGE, and the native T1 value were predictors of poor prognosis (adjusted hazard ratio for every 20-ms increase of native T1: 1.28; p = 0.003). In particular, the highest native T1 value provided further risk stratification regardless of the presence of LGE.</P> <P><B>Conclusions</B></P> <P>High native T1 value on noncontrast T1 mapping CMR is a novel, independent predictor of adverse outcome in patients with significant AS.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Paracentric Inversions Found in Prenatal Diagnosis

        Lee, Shin Yeong,Lee, Bom Yi,Park, Ju Yeon,Choi, Eun Young,Lee, Yeon Woo,Oh, Ah Rum,Ryu, Hyun Mee,Park, So Yeon Korean Society of Medical Genetics and Genomics 2013 대한의학유전학회지 Vol.10 No.2

        Purpose: This study was designed to confirm whether the paracentric inversions of fetuses and parents may be harmless. Materials and methods: We report 10 cases (0.14%) with paracentric inversions among 7,181 prenatal cases observed during prenatal diagnosis performed at Cheil General Hospital between January 2009 and June 2013. We used cytogenetic GTL- and RBG-banding techniques. Results: Of the 10 cases, nine cases were transmitted from each of the parents, and one case was de novo. Nine cases were phenotypically normal up to one month of age after birth. One case was lost to follow-up. We present prenatal diagnosis and follow-up examination of the fetuses with paracentric inversion. Conclusion: Based on our cases, most paracentric inversions are considered to be harmless. The precise identification of paracentric inversions might be clinically important and helpful for genetic counseling.

      • Human Adipose Stem Cells Improve Mechanical Allodynia and Enhance Functional Recovery in a Rat Model of Neuropathic Pain

        Lee, Hye Yeong,Lee, Hye-Lan,Yun, Yeomin,Kim, Jin-Su,Ha, Yoon,Yoon, Do Heum,Lee, Soo-Hong,Shin, Dong Ah Mary Ann Liebert 2015 Tissue engineering. Part A Vol.21 No.13

        <P>Stem cells are a promising source of tissue engineering due to their differentiation potential. Today, direct transplantation of stem cells for cell therapy is commonly performed. However, in cases of nerve injury, direct transplantation of cells could lead to secondary nerve damage. Male Sprague-Dawley rats were randomized into four groups: the phosphate-buffered saline epineural transplantation (PBS-ENT) group, the PBS intraneural transplantation (PBS-INT) group, the human adipose-derived stem cells epineural transplantation (hASCs-ENT) group, and human adipose-derived stem cells intraneural transplantation (hASCs-INT) group. Transplantation was conducted 1 week later after inflicting a crush injury with subsequent observation for 5 weeks. To evaluate pain, each group was examined with regard to paw withdrawal latency and evoked potentials. The sciatic functional index (SFI) was calculated to estimate functional recovery. The sciatic nerve was also examined histologically. The hASCs-ENT group showed a more rapid paw withdrawal threshold and SFI recovery than the other groups (p<0.05). The hASCs-ENT group also showed shorter initial latencies in both somatosensory evoked potential (SSEP) and motor evoked potential (MEP) than the PBS-INT group (p<0.05). In addition, the N1 latency of the MEP and the N1 and P1 latencies of the SSEP were significantly shorter than those of the PBS-INT group (p<0.05). Histological examination revealed that the transplanted groups showed better neural recovery and remyelination than the groups injected with PBS. These results show that the transplantation of hASCs into the injured sciatic nerve improved mechanical allodynia and functional recovery as determined by the paw withdrawal test, SFI analysis, and electrophysiological studies. ENT is superior to INT in terms of invasiveness and better outcomes.</P>

      • Breakfast consumption and depressive mood: A focus on socioeconomic status

        Lee, Sang Ah,Park, Eun-Cheol,Ju, Yeong Jun,Lee, Tae Hoon,Han, Euna,Kim, Tae Hyun Elsevier 2017 Appetite Vol.114 No.-

        <P><B>Abstract</B></P> <P>Skipping breakfast can be potentially harmful because breakfast consumption is considered one of the important health-related behaviors that benefit physical and mental health. As the rate of depression has increased recently, we investigated the association between the frequency of eating breakfast and depression in adults. We obtained the data from the 2013 Korean Community Health Survey; a total of 207,710 survey participants aged 20 years or over were studied. Participants were categorized into three groups by the frequency of breakfast consumption as follows: “seldom,” “sometimes,” and “always.” We performed a multiple logistic regression to investigate the association between breakfast consumption and depressive mood. Subgroup analyses were conducted by stratifying socioeconomic variables controlling for variables known to be associated with depressive symptoms. Participants who had breakfast seldom or sometimes had higher depressive symptoms than those who always ate breakfast (“seldom”: OR = 1.43, 95% CI 1.36–1.52; “sometimes”: OR = 1.32, 95% CI 1.23–1.40). Subgroup analyses showed that this association was more marked in those who were 80 years or older, those who had low household income, or those with elementary school education level or less. The result of this study suggests that lack of breakfast consumption is associated with depression among adults with different socioeconomic factors.</P>

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