실험적 진폐증에서 투여약제에 따른 면역학적 병리학적 조직변화

윤임중,임현우,노영만,오상용,정장영,임영,김경아 가톨릭 대학 산업의학 쎈타 산업의학연구소 1993 韓國의 産業醫學 Vol.32 No.2

To access the effects of some drugs such as piperazine phosphare, azathioprine and allopurinol in the experimental pneumoconiosis, 263 rats weighted 240-320 gm was divided into the control and eight experimental groups. To each group, the turbid solution mixed free silica, talc and natural coal dust of 50 mg in 0.8 ml saline were instilled intratracheally. At the begining and 5th week of experiment, piperazine phosphate(8mg/week orally), aspirin(1.5mg/day intramuscularly), azathioprine(25mg/day orally) and allopurinol(1.5mg/day orally) were administered simultaneously, while the dust turbid solution was only given to the control group. For each group the change of body weight. dry right lung weight, cellularity including total cell, macrophage, lymphocyte and neurtrophil in bronchoalveolar lavage fluid, superoxide ion, hydroxyproline, leukotriene B₄, tumor necrotsis factor, prostaglandin E₂were examined, and observed the pathological chages in lung tissue. The results were as follow : 1. The larger amount of their instilled dust and the longer observation period, the severer pathological findings were found in the lung tissue of each experimental group. 2. The body and dry right lung wight was not significantly changed in the experimental groups compared with the control group. 3. The number of total cell in bronchoalveolar lavage fluid was markedly less in the experimental group than the control one, while no significant difference was found in the percent alveolar macrophages and lymphocytes in both groups. However, the percent of neutrophiles was usually lower than in the control group. 4. The amount of superoxide ion was frequently less in the experimental group compared with the control one. 5. The amount of hydroxyproline was significantly lower in the experimental group than in the control one. 6. The amount of leukotriene B₄was usually less in the drug administered group than in the control one. 7. The amount of tumor necrotic factor was also frequently lower in each experimental group than in the control one. 8. The amount of prostaglandin E₂was usually higher in each experimental group than in the control one.

침 시술로 발생한 Non-O1, Non-O139 Vibrio cholerae에 의한 패혈증

임태섭,지아영,이중희,장수연,김인수,김영주,김범경,김승업,박준용,안상훈,한광협,김도영 Ewha Womans University School of Medicine 2013 EMJ (Ewha medical journal) Vol.36 No.S

Vibrio cholerae is mainly known to cause gastrointestinal infection after seawater exposure or raw seafood intake. It is rarely reported to cause cellulitis or sepsis, but threre has been no known case after acupuncture. Herein, We report a 56-year-old cirrhotic patient of non-O1, non-O139 Vibrio cholerae septicemia caused by cellulitis of both lower extremities after acupuncture.

휴대용 근적외분광분석기를 이용한 유탕면의 수분 함량 측정 : Infrared(NIR) System

임현량,김도형,우영아,김효진 동덕여자대학교 종합약학연구소 2002 동덕약학연구지 Vol.6 No.-

This experiment was carried out to determine non-destructively water content in a intact fried noodle in oil by portable near-infrared system. Water content was ranged from 0 to 14.3w/w% and the near infrared (NIR) measurements were made on 70 intact samples over the spectral range 1100-1750nm. We found the variation of absorbance band due to OH vibration of water in the noodles depending on the concentration change around 1450nm in the second derivatives spectra. Partial least squares(PLS) regression models were set up using a calibration set(42 E.A.) and a validation set(28 E.A.) between the NIR response and value from loss on dry. Various pretreatments of the spectra were examined: the smallest stnadard error of prediction(0.35%) was obtained using autoscaling spectra over 1100-1700nm. 10 factors were required for the PLS model to give a good relationship between the spectral information and the noodle water content. In order to validate the developed calibration model, routine analyses were performed using other intact noodles. Water contents from the NIR calibration model were compared with the values from loss on dry and the results showed good correlation with those of loss on dry. This study showed that the rapid and non-destructive determination of water content in a intact fried noodle in oil was successfully performed by portable NIR system.

Are Adolescents with Internet Addiction Prone to Aggressive Behavior? The Mediating Effect of Clinical Comorbidities on the Predictability of Aggression in Adolescents with Internet Addiction

Lim, Jae-A,Gwak, Ah Reum,Park, Su Mi,Kwon, Jun-Gun,Lee, Jun-Young,Jung, Hee Yeon,Sohn, Bo Kyung,Kim, Jae-Won,Kim, Dai Jin,Choi, Jung-Seok Mary Ann Liebert 2015 CYBERPSYCHOLOGY BEHAVIOR AND SOCIAL NETWORKING Vol.18 No.5

<P>Previous studies have reported associations between aggression and Internet addiction disorder (IAD), which has also been linked with anxiety, depression, and impulsiveness. However, the causal relationship between aggression and IAD has thus far not been clearly demonstrated. This study was designed to (a) examine the association between aggression and IAD and (b) investigate the mediating effects of anxiety, depression, and impulsivity in cases in which IAD predicts aggression or aggression predicts IAD. A total of 714 middle school students in Seoul, South Korea, were asked to provide demographic information and complete the Young's Internet Addiction Test (Y-IAT), the Buss-Perry Aggression Questionnaire, the Barratt Impulsiveness Scale-11, the State-Trait Anger Expression Inventory-2, the Beck Anxiety Inventory, the Beck Depression Inventory, and the Conners-Wells Adolescent Self-Report Scale. Three groups were identified based on the Y-IAT: the usual user group (n=487, 68.2%), the high-risk group (n=191, 26.8%), and the Internet addiction group (n=13, 1.8%). The data revealed a linear association between aggression and IAD such that one variable could be predicted by the other. According to the path analysis, the clinical scales (BAI, BDI, and CASS) had partial or full mediating effects on the ability of aggression to predict IAD, but the clinical scales had no mediating effect on the ability of IAD to predict aggression. The current findings suggest that adolescents with IAD seem to have more aggressive dispositions than do normal adolescents. If more aggressive individuals are clinically prone to Internet addiction, early psychiatric intervention may contribute to the prevention of IAD.</P>

자연과 수업시 교사가 아동에게 제공하고 있는 뇌친화적 요소에 관한 연구

임채성,김병철,류양순,이영아 부산교육대학교 과학교육연구소 1999 科學敎育硏究 Vol.24 No.-

Educational practices should be based on the sound information about the structure and function of human brain. Recently, with the result of advancement in technology, inner workings of our brain were sufficiently accumulated to actually apply to the educational practices. The eight brain-compatible elements suggested by Kovalik & Olsen(1994) were based on these knowledge about brain. This study was undertaken with the purpose of providing insights into science teaching-learning based on the brain-compatible elements derived from several brain-based learning principles. To accomplish this purpose, we explored how the elements were provided to children by teachers in science instruction. The results as follows. The levels of appreciation of the elements by teachers were high. Especially, the appreciation element of cooperation in science teaching was relatively higher than those of others. Furthermore, they had attitudes to have children relate the science subject to their real lives. For one particular element, that is, enriched environment, it was found to be relatively less appreciated, probably because of the lack of resources such as books, videos, CD, pictures, regularly scheduled guest speakers, and the others to support science contents. These findings provide a basis for understanding the roles of the brain-compatible elements in learning science. The results also highlight the need for teachers to aware of and implement the elements to create environments which encourage the maximization of the brain potentials of children when teach science subjects.

석유화학공장 근로자에서 발생한 재생불량성 빈혈 1례

박영만,임영,강성규,김지홍,이종욱,최용휴,김경아 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.2

Aplastic anemia is characterized by pancytopenia with hypocellular bone marrow. Fifty percent of the cases are idiopathic and the rest are caused by various agents including drugs, chemicals, radiation and viruses. It is difficult to link specific etiologic agents, especially chemicals to the development of aplastic anemia because multiple or unknown exposures may be involved in. Benzene, a common industrial chemical and a component of gasoline, may lead progressively to pancytopenia, aplastic anemia and leukemia when exposed. A petrochemical worker with aplastic anemia was referred to our hospital to evaluate a relationship between the job history and the disease. He worked in the petrochemical plant for 21 years and was exposed to low-level benzene. There was not anyother etiologic agent except benzene and this is the case report of aplastic anemia which possibly due to benzene exposure.

다중지능 활동이 초등학교 아동의 과학학습에 미치는 영향

이영아,임채성 부산교육대학교 과학교육연구소 2000 科學敎育硏究 Vol.25 No.-

To examine the effects of multiple intelligences (MI) activities on learning science, the study compared and analyzed the classes of using MI and traditional instruction of fifth grade students. The patterns of using the MI by students, the science attitudes, and the achievements of science were compared. In the development of MI, there were no significant differences between the experimental and comparison groups. However, each mean score of MI measured after the instruction showed more improvement in the experimental group than comparison group, which indicates the long-term use of MI activities in science instruction can help the development of MI. The changes of the science attitudes and achievements didn't show statistically significant differences, but, from the interviews with the children, they showed considerable interests at their own planning of experiments and activities with peers, and actively engaged in the instruction. The science instruction which the children used MI on their own choices more contributed to achievement than those of traditional one. Several implications on science education were also discussed.

수종의 니켈-티타늄 폐쇄형 코일 스프링의 하중-변위 특성 및 소성 변형 비교

손아영,임성훈 대한치과교정학회 2009 대한치과교정학회지 Vol.39 No.5

Objective: NiTi closed coil springs were reported to have relatively constant unloading forces. However, the characteristics of NiTi closed coil springs from various manufacturers have not been elucidated. The purpose of this study was to compare load-deflection characteristics of various NiTi closed coil springs and to find out the optimal range of extension. Methods: Seven kinds of NiTi closed coil springs from five manufacturers were tested. Load deflection curves were obtained at extension ranges from 2 mm to 30 mm. Also, springs were kept extended during a 4 week period, and then load deflection curves were obtained again. Results: Sentalloy (Tomy) and Jinsung blue (Jinsung) showed superelasticity in every extension ranges tested and showed plastic deformation of less than 1 mm. Ni-Ti (Ormco) showed superelasticity only after the springs were extended at or more than 10 mm, thereby meaning that clinicians should extend these springs at or more than 10 mm to utilize the superelasticity. Orthonol (RMO) and Nitanium (Ortho Organizers) did not show superelasticity. After 4 weeks of extension, all springs showed plastic deformation less than 1 mm when the extension was at or under 25 mm. Conclusions: The superelastic behavior of NiTi closed springs were different among various NiTi spring products, and some NiTi closed springs failed to show superelasticity. 폐쇄형 니켈-티타늄 코일 스프링은 탈부하 과정에서 힘이 거의 일정하게 유지되는 초탄성을 보이는 것으로 알려져있으나, 각 제조사에 따른 니켈-티타늄 스프링의 실제 특성에 대한 보고는 부족하다. 따라서 본 연구에서는 수종의 폐쇄형 니켈-티타늄 코일 스프링들의 하중-변위 특성과 소성 변형에 대해 비교하고 임상적으로 적용 가능한 신장 범위에 대해서 알아보고자 하였다. 다섯 개 제조회사에서 생산된 일곱 종의 폐쇄형 니켈-티타늄 코일 스프링을 각 종류별로 2 mm, 5 mm, 10 mm, 15 mm, 20 mm, 25 mm, 30 mm로 신장시켜 하중-변위 곡선을 얻은 후 같은 길이로 4주간 유지시킨 후 다시 하중-변위 곡선을 얻었다. 실험 결과 Sentalloy (Tomy, Tokyo, Japan), Jinsung (Jinsung, Seoul, Korea)은 모든 범위에서 초탄성을 나타내며 영구변형도 1 mm 이하로 작아 가장 바람직한 물성을 보였다. 반면 Ni-Ti (Ormco, Orange, CA, USA)는 10 mm부터 초탄성 구간을 보였는데, 이는 이러한 스프링을 적용 시에는 10 mm 이상 신장시켜야 초탄성 성질을 활용할 수 있다는 것을 의미한다. Orthonol (RMO, Denver, CO, USA)과 Nitanium (Ortho Oganizers, San Marcos, CA, USA)은 초탄성을 보이지 않았다. 4주 동안 신장 후의 소성 변형 정도를 측정한 결과 25 mm 이내의 신장 범위에서는 1 mm 이하의 소성 변형만이 나타났다. 폐쇄형 니켈-티타늄 코일스프링의 초탄성 성질은 제조사에 따라 다양하게 나타났으므로, 임상 적용 시 이를 고려하는 것이 바람직하다.

열공성 뇌경색과 뇌내출혈의 위험인자 비교

이장준,이현아,최종환,이형,임정근,이상도,박영춘 계명대학교 의과학연구소 2000 계명의대학술지 Vol.19 No.2

Cerebral small vessel disease is the most important cause of lacunar infarction (LI) and intracerebral hemorrhage (ICH). It is generally postulated that, in its early stages, the vascular lesion engenders vessel wall fragility and ICH. But if rupture dose not occur, segmental vessel occlusion evolves, producing LI. It may be a common aging phenomenon that is exacerbated by hypertension and diabetes mellitus. This study was performed to evaluate risk factors of LI and ICH. We reviewed retrospectively the medical records of 690 patients (254 LI, 436 ICH) with stroke who were admitted to Keimyung University Dongsan Medical Center from January 1995 to December 1998. The major risk factors including age, sex, hypertension, diabetes mellitus and several minor risk factors were analyzed in these patients. Older age (p<0.01), male sex(p<0.01), hypertension with treatment(p<0.01), hypertension with long duration(p<0.01) and hypertriglyceridemia(p<0.01), cigarette smoking(p<0.01) were significantly more frequent in LI. Younger age(p<0.01), female sex(p<0.01) and hypertension without treatment(p<0.01), hypertension with short duration(p<0.01) were more frequent in ICH. The prevalence, duration and treatment of diabetes mellitus were not different between these two groups. This study show that the age, sex, treatment of hypertension, duration of hypertension and cigarette smoking seem to be significant risk factors between LI and ICH.

한국비서자격시험의 개선점과 비교연구

남자현,이미정,이미영,이아영,정해금,최유정,이미숙,전인선,정혜림 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17