腦電算化斷層撮影을 通한 腦硬塞患者 20例에 對한 硏究

黃忠淵 圓光大學校 韓醫學硏究所 1995 원광한의학 Vol.5 No.1

The author analyzed 20 cases of cerebral infarction patients conformed by brain C.T. scan, who admitted to the Oriental Medical Hospital of Won Kwang University in Gwang Ju, from June 1,1994 to November 30,1994. We've analyzed these 20 cases in clinical point of view. The results were obtained as follows; 1. The digree of recovery after treatment, significant recovery was seen in 33.0%, the good recovery was seen in 50.4%, unchanged recovery was seen in 16.5%. 2. In general, the efficiency of the cases whose size of infarction was small were good, the efficiency of the cases whose situations and the size of infarction was large or the incidence of hemorrhage was occur were bad. 3. According to the situation of infarction area, various crinical symptoms were obtained. 4. The cases of Grade Ⅰ, Grade Ⅱ, Grade Ⅲ patients who can walk were increased from 5(25%) to 12(60%), and the cases of GradeⅣ, GradeⅤ patients were decreased from 15(75%) to 8(40%).

胃癌의 東西醫 治療에 관한 文獻的 考察

黃忠淵 圓光大學校 韓醫學硏究所 1997 원광한의학 Vol.7 No.1

癌(惡性新生物)은 오늘날 우리나라 成人死亡原因 1, 2위를 차지하며 전세계적으로 가장 무서운 疾病중의 하나이다. 癌의 治療는 지금까지 西洋醫學 위주로 手術療法, 化學療法, 免疫療法등의 治療가 행해지고 있으나 副作用과 毒作用이 심하여 필요한량의 治療를 끝까지 받지 못하는 경우가 많다. 또 免疫治療는 費用이 너무 많이들며 患者의 苦痛도 심하다. 最近에는 癌에 대한 東·西의 結合治療는 中半期 胃癌患者에 있어서 生存期間을 年長하고 化學治療 및 放射線療法의 독·부작용을 경감시켜 삶의 질을 높이고 體內의 건강상태와 면역기능을 높여 胃癌患者의 삶의 질을 높이고 生存期間을 年長시켰다. The following conclusions were obtained after bibliographic investigation on the therpy of gastric cancer by western oriental, and intergrated oriental and western medicine. 1. The major causes of gastric cancer are geographical environment, meal habit, inheritance and other diseases in the stomach, and its pathogenesis is stagnation of qi(氣滯鬱結), intemperance of food(飮食不節), weakness and coldness in spleen and stomach(脾胃虛寒), and stagnation of qi and blood(氣滯血瘀). 2. Treatment of gastric cancer by western medicine includes surgery, chemotherapy, radiotherapy and immunotherapy. 3. Treatment of gastric cancer by oriental medicine based on differentiation of symptom which classified into six types such as disharmony between liver and stomach(肝胃不和), impairment of yin by evil heat in stomach(胃熱傷陰), weakness and coldness in spleen and stomach(脾胃虛寒), obstruction of poisonous stagnant blood(瘀毒內阻), coagulation of dampness and phlegm(痰濕疑結), debility of qi and blood(氣血傷虧) with single recipe or empirical prescription. 4. Treatment by intergrated oriental and western medicine improved survival rate and quality of life as proper therapy such as herb medicine, surgery, chemotherapy or radiotherapy was applied according to the stage of the disease. Herb medicine promoted recovery and improved survival rate after surgery. Radiotherapy and intergrated therapy reduced adverse effect by radiotherapy and improved therapeutic effect and survival rate. Chemotherapy and intergrated treatment reduced side effect by chemotherapy and improved quality of life and survival rate. These results suggest that therapy of gastric cancer should be applied with intergrated oriental and western medicine from diagnosis to all the stage of treatment for promoting therapeutic effect. And further investigation on this therapy should be ensued.

삼황세제 가미방 외용이 NC/Nga 마우스의 아토피 피부염에 대한 효과

황충연,박민철,홍석훈,주현아,조현우,정수영,조정희,Hwang, Chung-Yeon,Park, Min-Cheol,Hong, Seok-Hoon,Joo, Hyun-A,Cho, Hyun-Woo,Jung, Soo-Young,Cho, Jeong-Hee 대한한방안이비인후피부과학회 2012 한방안이비인후피부과학회지 Vol.25 No.1

Objectives : In this study, Samhwangsaejaegami extract was tested to prove its anti-atopic dermatitis effect on NC/Nga mice. Methods : In order to evaluate the external use effects of Samhwangsaejae extract on anti-atopic dermatitis, the expression of filaggrin, serine palmitoyltransferase(SPT), and COX-2 were analyzed. In vivo study, clinical skin severity score, IgE, IL-4, IL-5 and IL-6 level were analyzed through NC/Nga atopic mice model after 12 weeks external treatment. Results : In vitro study results showed the reduction in the expression of filaggrin, SPT, and COX-2. In vivo study results demonstrated the significant reduction in clinical skin severity score, IgE, IL-4, IL-5, IL-6 expression level. Conclusions : These results showed Samhwangsaejaegami extract can be a promising candidate for anti-atopic dermatitis treatment.

腫瘤에 대한 최근 中醫 및 中西醫 결합치료 연구경향

황충연(Chung Yeon Hwang),홍철희(Chul Hee Hong) 한의병리학회 2004 동의생리병리학회지 Vol.18 No.6

肺癌의 東西醫結合治療에 關한 文獻的 考察

黃忠淵(Whang Choong-Yeon) 대한한의학회 1995 대한한의학회지 Vol.16 No.2

耳鍼療法을 利用한 耳鳴症 治療效果에 關한 臨床的 觀察

김성철,황충연,Kim, Seong-Cheol,Hwang, Chung-Yeon 대한한방안이비인후피부과학회 1993 한방안이비인후피부과학회지 Vol.6 No.1

三次神經痛의 鍼灸治療에 關한 文獻的 考察

邊宰煐,黃忠淵,文錫哉,金庚植 대한한의학회 1993 대한한의학회지 Vol.14 No.2

탁리소독음(托裏消毒飮) 합(合) 황련해독탕(黃連解毒湯)의 아토피피부염에 대한 실험적 연구

원영호,황충연,임규상,김종한,고성규,이부균,이동효,김남권,Weon, Young-Ho,Hwang, Chung-Yeon,Lim, Kyu-Sang,Kim, Jong-Han,Ko, Seong-Gyu,Lee, Boo-Kyun,Lee, Dong-Hyo,Kim, Nam-Kwen 대한한방안이비인후피부과학회 2011 한방안이비인후피부과학회지 Vol.24 No.1

Objective : This Experimental study was done to investigate the Effect of Taklisodok-um and Hwangryunhaedok-tang(TH) on Atopic Dermatitis. Methods : We assessed effects of TH on the IgE, IL-4, IL-5, IL-6, IgM, IgG1, IFN-${\gamma}$ in vivo, on the IL-4, IL-5, CCR3 in the skin tissues of ear and dorsum with NC/Nga mice. And we assessed effects of TH on the COX-2, IL-$1{\beta}$, TNF-${\alpha}$, IL-6 with RAW 264.7 cell. Results and Conclusion : 1. IgE, IL-4, IL-5, IL-6, IgM, IgGl levels in the serum of TH treated NC/Nga mouse group were decreased compared to the untreated control mice. IFN-r showed a increase in the experimental group compared to the untreated control group. The spleen weight of TH treated NC/Nga mice was decreased compared to the untreated control group. 2. mRNA expression levels of IL-4, IL-5 and CCR3 in the skin tissues of TH treated NC/Nga mice were decreased, and expression levels of IL-6 in the skin tissues of TH treated NC/Nga mice were decreased compared to the untreated control group. IFN-${\gamma}$ mRNA expression levels were increased compared to the untreated control group. 3. Judged from that IL-$1{\beta}$, TNF-${\alpha}$, IL-6 express of gene, effect of inflammatory Cytokines revelation were decreased compared to the untreated control group. 4. Depend on the strength of TH, inflammatory RAW 264.7 in the serum of TH were inhibited compared to the untreated control serum that leaded a COX-2 activity model. 5. Histological observation of the ear and skin tissues showed that the extents of inflammation and infiltrated immune cells in the epidermis and dermis of TH treated NC/Nga mice were highly reduced compared to the untreated control group.

이명증 환자 중증도와 삶의 질의 상관 연구

서은성,황충연,임규상,강형원,박민철,김남권,Seo, Eun-Sung,Hwang, Chung-Yeon,Lim, Kyu-Sang,Kang, Hyuong-Won,Park, Min-Chol,Kim, Nam-Kwen 대한한방안이비인후피부과학회 2012 한방안이비인후피부과학회지 Vol.25 No.4

Objective : This study was done to investigate the correlation between general quality of life(QOL) and disease specific QOL of tinnitus patients. Methods : 2009 National health and nutrition survey(NHNS) data were employed for analyzing the mean estimates of total population and tinnitus sub-group patients, and predicting the regression equation of mapping between EQ-5D and disease severity. Baseline statistical analyses and normality tests were done by using Student t-test, Chi-square test, Shapiro-Wilk test and ladder test. Hierarchial regression analyses were performed using related variables and predicted the optimal regression equations. Statistical significance was achieved if the probability was less than 5%. Results : Firstly, the standardized prevalence of tinnitus patient in South Korea was 18.69% and over 90th age-group was relatively higher than other groups. Mean value of domestic QOL measured by EQ-5D was estimated as 0.9486 and QOL of tinnitus subgroup(0.9169) was lower than the non-tinnitus subgroup(0.9559), significantly. Stratified by age and sex, QOLs of all sub-groups with tinnitus were lower than without tinnitus sub-groups significantly. Regression equations from 2009 NHNS data were developed using hierarchial regression analysis which is as follows. $$Y_{EQ-5D}=0.9224-0.0079{\times}T1-0.0261{\times}T2-0.0951{\times}T3+\sum_{i=1}^{n}{\beta}_i{\times}X_i\\{\hspace{95}}(0.0106){\hspace{3}}(0.0037){\hspace{30}}(0.0072){\hspace{30}}(0.0038)$$ ($X_i$=Other explanatory variables except Tinnitus QOL1, 2, 3, ${\beta}$= Regression Coefficient of Model 4) Conclusion : We confirmed the correlation among THI and EQ-5D and HUI-III, and developed the inference for regression equation of EQ-5D.

이명(耳鳴)의 동(東)·서의학적(西醫學的) 문헌(文獻) 고찰(考察)

허은선,황충연,Heo, Eun-Sun,Hwang, Chung-Yeon 대한한방안이비인후피부과학회 2016 한방안이비인후피부과학회지 Vol.29 No.4

Objectives : This study is performed to investigate the therapy on tinnitus through the literature of Eastern and Western medicine. Methods : This study review the definition, etiology, classification, internal and external methods of treatment of tinnitus based on 50 articles of Eastern medicine, 16 articles of Western medicine about the treatment of tinnitus. Results : The results were as follows. 1. In Eastern medicine, the cause and mechanism of disease of tinnitus arose from the state of qi-blood deficiency, internal dampness-heat and depression stagnation. In Western medicine, there are mainly caused by damage to the auditory system the lower induced changes in the upper. 2. In Eastern medicine, differentiation of syndromes classifies clinical aspects, and cause and mechanism of disease. In Western medicine, it divides into an generating region, clinical and associated symptoms aspects. 3. In Eastern medicine, internal method of treatments of tinnitus are divided into four treatments. In Western medicine, internal methods of tinnitus are vasodilators, blood-flow improvers, Metabolism improvers etc. 4. In Eastern medicine, external method of treatments of tinnitus are paste preparation method, powder preparation method, pill preparation method, acupuncture & moxibustion method. In Western medicine, external method of treatments of Tinnitus are divided into injection, other surgical therapies and adjuvant therapy. Conclusions : Until now, there is no perfect, effective single treatment. We think that Eastern medicine approach and treatment can be helpful to overcome the limitations of tinnitus cure.