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황경균 대한치과의사협회 2023 대한치과의사협회지 Vol.61 No.4
Pain control according to sensory nerve innervation in the oral and maxillofacial area is an important part of clinical dentistry for treating diseases of teeth, periodontal tissue, oral mucosa, temporomandibular joint, and maxillofacial area. Local anesthesia has been used the basic pain control procedure in dental treatment. Dental local anesthesia is a basic procedure in the curriculum of dental schools, and is the most frequently used dental procedure by many dentists in clinical practice. As one of these procedures, we would like to review the considerations of whether clinical guidelines for these procedures are necessary
가토 하악골 골신장 후 맥동전자기장이 조기 골경화에 미치는 효과에 대한 연구
황경균,조태형,송윤미,김도균,한성희,김인숙,황순정,Hwang, Kyung-Kyun,Cho, Tae-Hyung,Song, Yun-Mi,Kim, Do-Kyun,Han, Sung-Hee,Kim, In-Sook,Hwang, Soon-Jung 대한악안면성형재건외과학회 2007 Maxillofacial Plastic Reconstructive Surgery Vol.29 No.2
Introduction: Distraction osteogenesis is widely used as for bone lengthening in patients with maxillofacial deformity and alveolar bone atrophy. One of the major problems in distraction osteogenesis is long consolidation period for 2-3 months, in which the devices have to be fixed on the bone to prevent relapse. It results in scar formation on the face, disturbance of mastication and speech. This study was performed to evaluate the stimulating effect of pulsed electromagnetic field on the early bone consolidation in distraction osteogenesis. Materials and methods: Total 10 rabbit were used (5 for control group, 5 for experimental group). A vertical osteotomy in the mandibular body was performed and the distraction device was fixed. After 5 days distraction was done 1mm per a day for 7 days. A pulsed electromagnetic field (38 Gauss, 60 Hz) was applied for 8 hours per day and it continued for 5 days immediately after distraction in the experimental group. Both groups were sacrificed after 2 weeks. Histological specimens with H&E and Masson Trichrome staining were made and histomorphometrically analysed with image analyser. Results: The device for distraction osteogenesis was displaced in one animal for each group, therefore, only four animals in both groups were evaluated. In both groups, a new bone formation was observed in the distracted area after 2 weeks. The bone formation was enhanced in the experimental groups ($31.76{\pm}8.68%$) compared with control group ($9.94{\pm}3.23%$), its difference was statistically significant (p<0.001). Conclusion: This study suggests that electrical stimulation with electromagnectic field may be effective in the early bone formation after distraction osteogenesis. Further studies with large number of animals are needed before clinical application.
구강 악성 흑색종에서 PCNA 발현에 관한 면역조직화학적 연구
황경균,남윤우,이재일,이종호,심광섭,김명진 大韓顎顔面成形再建外科學會 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.6
Malignant melanoma arising from the mucosa of head and neck region was rare and showed poor prognosis. Some of malignant melanoma were transformed from benign melanotic lesion. Malignant melanoma had high cellular proliferation and rapid growth. The percentage of PCNA-positive cell (labeling index) is high in many malignant tumor. So we compared the pattern of PCNA expression in the melanotic lesion. We performed the immunohistochemical study in malignant melanoma(19 cases), benign melanotic macule(24 cases) and normal mucosa(20 cases) were diagnosed in Seoul National University Dental Hospital between 1980 and 2000. Positive PCNA staining was found mainly in malignant melanoma. The mean PCNA expression in malignant melanoma, melanotic macule, normal tissue were 29.2%, 1.4%, 0%, respectively. Significant differences in PCNA expression were noted between malignant melanoma and melanotic macule(p<0.01), normal mucosa(p<0.01). These result suggested that the PCNA expression seems to be used as a diagnostic indicator for malignancy in malignant melanoma and melanotic lesion.
황경균(Kyung-Gyun Hwang),송승일(Seung-Il Song),김상우(Sang-Woo Kim),이성훈(Sung-hoon Lee),김영면(Young-Muen Kim),심광섭(Kwang-Sup Shim) 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.5
Sinus floor augmentation has been proven an effective treatment procedure to increase bone volume in the posterior edentulous maxilla. Autogenous bone considered to be the best material for reconstructive bone surgery and has been successfully used as a graft material to augment posterior maxilla. However, the collection of autogenous bone required extra risks for morbidity and complaints. So, various bone graft materials included β-tricalcium phosphate(β-TCP) has been introduced for replacing the autogenous bone. The objective of this clinical study was to determine the predictability of endosseous implant placed in a maxillary sinus with β-TCP grafting. We performed sinus elevation with β-TCP to install the implant in the 10 maxillary cases. The prosthetic procedure was performed 6-9 months after. The implant-prosthetics was checked about 1 year. We checked the implant and measured the maximum bite force to evaluate the function of the implant. There was not observed the specific problem and complication in dental implant and maxillary sinus in the grafted materials. The maximum bite force was 558N in case of natural tooth, 365N in implant without grafting, 318N in implant with β-TCP grafting. There was no significant difference between with and without sinus grafting on maximum bite force(p>0.05). As though the long term check-up is needed, the grafting of β-TCP as a osteoconductive materials can expand the volume and induce dense new bone formation in maxillary sinus. So, this short-term results support that β-TCP can be a suitable material for sinus augmentation.
가토 두개부 골결손에서 맥동전자기장이 골형성에 미치는 영향에 관한 연구
황경균(Kyung-Gyun Hwang),이종환(Jong-Hwan Lee),김명진(Myung-Jin Kim),심광섭(Kwang-Sup Shim),김종원(Jong-Won Kim) 대한구강악안면외과학회 2002 대한구강악안면외과학회지 Vol.28 No.4
Pulsed electromagnetic field (PEMF) was used first to induce osteogenesis in 1974. The appliance which was consisted of the Helmholtz coil configuration have used to osteogensis. The objective of this study was to determine whether PEMF, a frequency of 100 Hz and magnetic field strength of 38 gauss applied to the calvarial defect in rabbit, could affect the induction of osteogenesis and the healing of the graft bone. This field should not produce excitation of nerve or muscle and heating the tissue. To evaluate the effect of PEMF on osteogenesis, 16 rabbit under the same condition was divided into 8 experimental groups and 8 control groups. 10 mm calvarial bone defects were formed around sagittal suture. The defect of left side was left without graft while the defect of right side was grafted by bone harvested from left side. A pulsed electromagnetic field was applied for 8 hours per day. Each group was sacrificed after 1 week, 2 weeks, 4 weeks, 8 weeks. Microscopic specimens were obtained from the calvarial bone defects and surrounding tissue using Hematoxylin-Eosin staining method. The results were as follows. 1. In the group which pulsed electromagnetic field was applied, new bone formation filled up the defect was observed after 4 and 8 weeks effectively. 2. There are no difference in the healing period for the fusion between the bone and graft bone. According to the result, the PEMF with 38 Gauss, 100 Hz was very effective in the healing of bone defect and new bone formation. So The PEMF will be useful in clinical aspect for oseteogenesis.
비스포스포네이트(Bisphosphonate)를 복용하는 환자에서 발생하는 골괴사증
황경균(Kyung-Gyun Hwang) 대한치과의사협회 2011 대한치과의사협회지 Vol.49 No.7
Bisphosphonates are widely used in the management of osteoporosis patients. Many reports and clinical studies have published a relationship between necrotic bone lesions localized to the jaw and the use of chronic bisphosphonate therapy. This osteonecrosis named bisphosphonate-related osteonecrosis of the jaw(BRONJ). This article described the mechanism, chemical structure, indication, risk factor of the bisphosphonate