건강정보 이해능력과 코로나19 감염에 대한 염려의 관련성

허민희,백세종,노진원 사단법인 대한보건협회 2023 대한보건연구 Vol.49 No.1

Purpose: This study has attempted to analyze the association between health literacy and health concerns of COVID-19 infection by using the Korea Community Health Survey, nationally representative data collected under complex sample designs. Methods: The concern of COVID-19 infection was used as the independent variable and main dependent variable was health literacy. In this study, social determinants of health were considered as control variables. The relationships of health literacy with health concerns of COVID-19 infection were analyzed using binary logistic regression. Results: As a result, people with low health literacy were more likely to have health concerns of COVID-19 infection. And sex, age, marital status, household income, education level, unmet medical needs, health screening, residential area, reliability of social environment were significantly associated with health concerns of COVID-19 infection. Conclusions: This study revealed that health literacy was negatively associated with the health concerns of COVID-19 infection. People with low health literacy would be more likely to have low resilience on infodemic situation, distorted perceptions and uncertainty about COVID-19, leading to increased concerns of COVID-19 infection. Therefore, policymakers should support to enhance capacity to improve health literacy and delivery of accurate health-related information at the same time. 연구목적: 본 연구는 전국 성인을 대상으로 한 2021년 지역사회 건강조사 원시자료를 활용하여 건강정보 이해능력과 코로나19 감염에 대한 염려의 관계성을 파악하고자 하였다. 연구방법: 종속변수는 코로나19 감염에 대한 염려, 독립변수는 건강정보 이해능력이며, Healthy People 2030의 건강의 사회적 결정요인을 재구성하여 통제변수를 고려하였다. 층화변수, 집락변수 및 개인 가중치를 적용한 복합표본분석을 수행하였으며, 건강정보 이해능력 수준과 코로나19 감염에 대한 염려의 관련성 파악을 위해 이분형 로지스틱 회귀분석을 실시하였다. 모든 통계적 처리는 SAS 9.4를 사용하여 수행되었다. 주요결과: 분석결과, 건강정보 이해능력 수준이 높을수록 코로나19 감염에 대한 염려가 낮았다. 또한 성별, 연령, 혼인상태, 가구 월소득, 교육수준, 미충족 의료 여부, 건강검진 수검 여부, 거주지역, 사회환경에 대한 신뢰도가 코로나19 감염에 대한 염려와 유의미한 관련성이 있었다. 결론: 건강정보 이해능력 수준이 낮은 개인은 감염병의 실제 위험보다 더 많은 두려움에 노출된 정보전염병 상황에 낮은 회복 탄력성을 보일 가능성이 높으므로 코로나19에 대해 왜곡된 인식과 불확실성이 증가하여 코로나19 감염에 대한 더 높은 염려를 보일 것으로 판단된다. 따라서 코로나19의 장기화 및 위드 코로나로 방역이 일상생활과 동조화된 상황에서 개인수준의 건강정보 이해능력 제고를 위한 역량 강화와 정부차원의 정확한 정보의 전달과 환경 조성에 대한 지원이 동시에 요구된다.

Downward bias of conductivity based point-of-care hemoglobin measurement compared with optical methods

허민희,김준현,김경우,조호재,최원주,김경태,김지연,이상일,박장수,김정원 대한마취통증의학회 2018 Anesthesia and pain medicine Vol.13 No.3

Background: Point-of-care (POC) arterial blood gas analysis (ABGA) is widely used for checking hemoglobin (Hb) level. However, there is the tendency of downward bias of conductivity-based POC ABGA Hb measurement compared with optical methods. Authors tried to correct that bias by linear regression equation. Methods: We retrospectively collected a total of 86 Hb result pairs during surgeries. Hb measured by the Sysmex XE-2100 in the laboratory was set as the gold standard and was compared with that measured by the GEM Premier 3500. Data were compared using the Bland-Altman analysis, the reliability of transfusion decision was assessed using three-zone error grid. The linear regression analysis was performed to find out the relation between the Hb results of POC ABGA and those of laboratory based test. Results: The bias of the Hb measured between Sysmex XE-2100 and GEM Premier 3500 was −0.9 g/dl (P < 0.001, 95% confidence interval, −1.038 to −0.665 g/dl). The percentage error was 16.4%. According to error grid methodology, zone A, B and C encompassed 89.5%, 10.5% and 0% of data pairs. After adjusting the POC ABGA Hb values, the bias of the Hb measured by two methods was 0 g/dl (P = 0.991). The percentage error was 18.2%. The zone A, B and C encompassed 91.9%, 8.1% and 0% of data pairs. Conclusions: Hb measurements obtained with reference to conductivity via a POC ABGA were significantly lower than those obtained via optical methods. This bias may deserve attention of anesthesiologists when POC ABGA Hb level is used as a transfusion guideline.

군집분석을 활용한 지역별 건강격차 연구: 주관적 건강수준을 중심으로

허민희,백세종,김영진,노진원 한국보건행정학회 2023 보건행정학회지 Vol.33 No.2

Background: Personal socio-economic abilities are crucial as it affects health inequalities. These multidimensional inequalities acrossthe regions have been structured and fixed. This study aimed to analyze health vulnerabilities by regional cluster and identify regionalhealth disparities of self-rated health, using nationally representative cross-sectional data. Methods: This study used personal and regional data. Data from the Community Health Survey 2021 were analyzed. K-means clusteranalysis was applied to 250 si-gun-gu using administrative regional data. The clusters were based on three areas: physicalenvironment, health-related behaviors and biological factors, and the psychosocial environment through the conceptual frameworkfor action on the social determinants of health. And binary logistic regression analyses were conducted to examine the differencesin self-rated health status by the regional clusters, controlling human biology, environment, lifestyle, and healthcare organizationfactors. Results: The most vulnerable group was group 3, the moderate vulnerable group was group 1, and the least vulnerable group wasgroup 2. The group 2 was more likely to have high self-rated health status than the moderate vulnerable group (odds ratio [OR],1.023; p<0.001). And the group 3 showed low self-rated health status than the moderate vulnerable group (OR, 0.775; p<0.001). However, the moderate vulnerable group had significantly higher self-rated health status than the most vulnerable group (group 2:OR, 1.023; p<0.001; group 3: OR, 0.775; p<0.001). Conclusion: These results demonstrate that community members’ health status is influenced by regional determinants of health andindividual levels. And these contribute to understanding the importance of specific and differentiated interventions like locallytailored support programs considering both individual and regional health determinants.

유방 정기검진 10년 결과 보고

허민희,송현정,고승상,이해경,강성수,이경상,조병제,김혜선,최종순,이지현 대한외과학회 2004 대한외과학회 학술대회 초록집 Vol.2004 No.10

질식분만이 회음부 하강과 음부신경 말단운동근 잠복기에 미치는 영향

허민희,최윤미,우상욱,김세중,홍기천,김종화,우제홍 대한대장항문학회 2000 Annals of Coloproctolgy Vol.16 No.2

Cancer stem cells in breast cancer

허민희 대한외과학회 2009 대한외과학회 학술대회 초록집 Vol.2009 No.11

Postoperative Thrombotic Microangiopathy with the Combined Administration of Tranexamic Acid and Batroxobin: Two Case Reports

허민희,김정현,김지연 순천향대학교 순천향의학연구소 2021 Journal of Soonchunhyang Medical Science Vol.27 No.1

Thrombotic microangiopathy (TMA) is a clinical syndrome characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end-organ damage. When TMA is suspected, accurate diagnosis is required; however, differential diagnosis is often difficult because each patient has various clinical features, and the causes of triggers may overlap. We report two cases of TMA that developed after surgeries in patients, with the combined administration of tranexamic acid and batroxobin intraoperatively. We need to consider the risk of adverse effects of the concomitant use of tranexamic acid and batroxobin for anesthetic management.

음주시작연령과 BMI의 연관성에 대한 융복합 연구: 성별 차이를 중심으로

허민희,장하은,정윤지,노진원 한국융합학회 2022 한국융합학회논문지 Vol.13 No.2

This study aims to explore the relationship between onset drinking age and the current Body Mass Index (BMI) level stratified by sex. This study used the data of Korea Community Health Survey (KCHS) 2019, of which 206,987 participants included in study populations for multivariable binomial logistic regression model. The study results show the evidence that the early age of onset alcohol consumption had significantly associated with abnormal BMI status in adult male. These results could be explained by high alcohol consumption and sex difference in social atmosphere which encourages men to drink more. Our finding suggest that the need to prevent problem drinking for reducing the long-term side effects of health. 본 연구는 성별에 따른 음주시작연령과 BMI 간의 상관관계를 파악하여 청소년기 음주행태와 성인기의 건강과의 관계에 대해 고찰하고자 한다. 본 연구는 2019년 지역사회건강조사를 활용하여 206,987명의 연구대상자를 대상으로 이분형 로지스틱 회귀분석을 실시하였다. 연구결과, 음주시작연령이 성인기 이전인 경우 성인 남성의 BMI가 비정상일 오즈값이 통계적으로 유의미하게 높았다. 이러한 연구결과는 남성의 높은 알코올 소비량과 음주에 대한 성별에 따른 차별적인 음주문화 때문인 것으로 설명할 수 있다. 본 연구는 성인기 이전의 조기음주가 야기할 수 있는 한시적인 어려움이 아닌 장기적인 건강 부작용 측면을 다룸으로써 자발적인 문제성 음주를 예방의 필요성을 강조하였다.

암줄기세포

허민희 한국유방암학회 2007 Journal of breast cancer Vol.10 No.3

Recent results have supported the cancer stem cells hypothesis in which tumors originate from tissue stem cells or their early progenitors and, as a result, produce tumors that retain stem cell properties. These properties include selfrenewal that drives tumorigenesis and differentiation that contributes to cellular heterogeneity. The number of these cells is very small, and is tightly controlled by the self-renewal pathway and the signals of their environment (niche). Evidence for the existence of cancer stem cells has been reported for a number of human cancers including leukemia, cancers of the breast, brain, and colon. Although our understanding of the biology of these cancer stem cells remains rudimentary, the existence of these cells has implications for current conceptualization of malignant transformation and targeted therapy for the treatment of cancer.

군집분석을 활용한 지역별 건강격차와 건강불평등 연구 - 주관적 건강상태를 중심으로

허민희,백세종,김영진,노진원 한국보건행정학회 2022 한국보건행정학회 학술대회 논문집 Vol.2022 No.1