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        • SCOPUSKCI등재

          Churg-Strauss 증후군 1예

          함정희,강민정,황규광,조소연,김지연 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.5

          Department of Dermatology, College of Medicine, Ewha Womans University, Seoul, Korea Churg-Strauss syndrome is a rare systemic vasculitis characterized by bronchial asthma, peripheral eosinophilia, paranasal sinus abnormality, mono- or polyneuropathy, nonfixed pulmonary infiltration, pathologic findings such as prominent eosinophilic infiltration, necrotizing angiitis and extravascular granuloma formation.We herein report a case of 20-year-old male who presented with tender grey polymorphic vesicles on palms, soles, fingers and toes that had developed 1 month ago. Laboratory studies revealed peripheral blood eosinophilia, positive p-ANCA and pulmonary infiltration. In the past history, he had had maxillary sinusitis, and he was also suffering from asthma. His skin biopsy revealed eosinophilic infiltrates and leukocytoclastic vasculitis.

        • 국민학교 학동들의 피부병 발생빈도에 관한 고찰

          咸姃希,鞠泓一 中央醫學社 1977 中央醫學 Vol.32 No.2

          2,710 pupils at W primary school in Seoul and 1,268 pupils at S primary school at country were analyzed in order to purse the tendency of skin diseases in school years on these days in Korea. The results are summarized as follows: 1) Most frequent age group is 9-11 years group. Seoul(57.26%) Country(64. 5%) 2) No significant sex difference is in country, but male prevalence is seen in Seoul. (1.7 times) 3) The top 10 diseases in Seoul are; Pityriasis alba (40. 3%) Angular cheilitis (9. 8%) Pigmented Nevus (8.5%) Atopic dermatitis (5.1%) Verruca vulgaris (4.5%) Keratosis pilaris (4.5%) Insect bite (4.2%) Molluscum contagiosum (3.4%) Freckle (3.1%) Burn scar (2.5%) 4) The top 10 diseases in country are: Angular cheilitis (40.5%) Pityriasis alba (30.3%) Pediculosis capitis (10. 1%) Tinea capitis (6.5%) Pigmented nevus (5.4%) Verruca vulgaris (1.7%) Papular urticaria (1.1%) Scabies (0.9%) Atopic dermatitis (0.8%) Eczematoid dermatitis (0. 7%) 5) Most significant differences between two areas: a) Pediculosis capitis and Tinea capitis were only seen in country. b) Incidence of Burn scar is 2.5% in Seoul. c) Incidence of viral infection (11.2%) increased in Seoul.

        • SCOPUSKCI등재

          Hydroquinone에 의한 알레르기성 접촉 피부염 1예

          함정희,이주은 대한피부과학회 1992 大韓皮膚科學會誌 Vol.30 No.3

          Tego (dodecylic aminoethyl glycine HCl) is an antiseptic detergent used abroad in hospitals, food industries, public baths, and for cleaning machinery. Allergic contact dermatitis may occur in hospital operating-room personnel, swimming instructors, and deep-sea divers. We present two cases of allergic contact dermatitis to Tego in two siblings after dressing the accidental abrasion with Tego . The patch test results showed a strong positive reaction to 0.1% Tego. (Kor J Dermatol 1992; 30(3): 385-388) Bleaching creams containing hydroquinone are modestly effective in treating some cutane ous pigmentary disorders. Hydroquinone creams frequently cause mild irritant reactions and postinflammatory hyperpigmentation, but rarely allergic reactions. A case of allergic contact dermatitis due to hydroquinone in a 21-year-old woman was confirmed by the patch test. (Kor J Dermatol 1992; 30(3): 381-384)

        • SCOPUSKCI등재

          냉동외과술의 치료효과 극대화를 위한 시술방법 및 적용시간 고찰 : 선택적 냉동용해이론 Theory of Selective Cryolysis

          함정희,명기범,황규광,신나라 대한피부과학회 2001 大韓皮膚科學會誌 Vol.39 No.7

          Background: Cryosurgery uses freezing temperatures to achieve specific effects on tissues, and this method has been used to treat various skin diseases for the last five decades. The modern cryosurgery is especially effective on the treatment of benign, premalignant and malignant lesions including keloid, hypertrophic scar and pigmented disease such as Ota nevus. The results of cryosurgery depend on such factors as types of cryogen, freezing and thawing time, and numbers of the freezing-thawing cycle. Objective : The purpose of this study is to show differences among groups of disease, sites of treatment and applying methods through comparing freezing and thawing time. And specifying the optimum applying methods for the treatment of each specific disease is studied. Method: To attain the goal of the study, operation records of 224 patients, who received cryosurgical treatment at the Ewha Woman's University Dongdaemoon Hospital, have been analyzed. Results: 1. The numbers of male and female patients of selected group were 74 and 150, respectively, and their ages between 2 and 54 years. Among the group, 42 patients had epidermal pigmentary disease, 77 had dermal pigmentary disease and 105 had scars. 2. Ratios of TT (thawing time) to FT (freezing time) were significantly different among groups of disease (p$lt;0.05). 3. Ratios of TT to FT were significantly different among groups of treatment site (p$lt;0.05). 4. Ratios of TT to FT showed great difference between the group of rolling method applied and one of pressure method applied (p$lt;0.05). Conclusion. The output of this study indicates that the result of the cryosurgery tends to be heavily influenced by the surgical method that is employed. It also proves that the pressure method tends to inflict more severe cryoinjury on the tissues than the rolling method. Each different tissue shows different sensitivity to the cold injury, and the longer the thawing time is, the more cryoinjury of tissues occurs. Therefore, to achieve the maximum therapeutic result while minimizing the undesired effect, adequate surgical method should be selected and applied to each specific disease. This concept is introduced in this study as $quot; Theory of Selective Cryolysis $quot; .

        • SCOPUSKCI등재

          두정부에 국한되어 발생한 결절성 열모증 1예

          함정희,김명화,황규광,조소연 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.3

          Trichorrhexis nodosa is the most common hair shaft anomaly in which there is a distinctive response to injury. The hair is fragile and on examination pale `node-like' swelling may be observed. It may affect normal hair following excessive or repeated trauma, or may occur after minimal trauma if there is an inherent defect in keratin synthesis causing abnormally brittle hair. We report a case of localized trichorrhexis nodosa in a 42-year-old male who had scratched frequently for the relief of the pruritus in the parietal area. Scanning electron microscopy revealed longitudinal fissures and fracture in the cortex. A paint brush effect was noted at the site of fracture.

        • SCOPUSKCI등재

          소아기 아토피 피부염이 가족에 미치는 영향에 관한 연구

          함정희,김성현,황규광,조소연,신나라 대한피부과학회 2000 大韓皮膚科學會誌 Vol.38 No.4

          Background:Childhood atopic dermatitis(AD) has a profound effect on the quality of life, disturbing family and social relationships. Stressful familial condition from the child's AD may aggravate AD itself but no information concerning the effect of childhood AD on family function is available in Korea. Objectives:The aim of this study was to show how AD effects families, to identify the areas of life most affected and to evaluate the relationship between the effect and severity of AD. Method:The 10-questionnaire item(Dermatitis Family Impact questionnaire[DFI]) with assessment of severity of AD was studied in AD patients and compared with control subjects. Results:The average of the total score of the DFI questionnaire in the AD group was significantly higher than that of the control group (P$lt;0.05) and was linearly related with AD severity, but not as highly (R²=0.161, P=0.003). The highest scoring question in the 10 questions of the DFI questionnaire was that of causing physical tiredness or mental exhaustion, and the lowest, that of time spent on shopping for the family. Conclusion:There is an obvious need to identify and to reduce the suffering of families of children with AD. The DFI may potentially be of value to help guide appropriate management of AD and as an added parameter in clinical trials concerning AD management.

        • Flashlamp-Pumped Pulsed Dye Laser를 이용한 소아화염상모반의 치료효과에 관한 연구

          함정희 梨花女子大學校 韓國生活科學硏究院 1992 韓國生活科學硏究院 論叢 Vol.50 No.-

          Portwine stain(pws) is a congenital vascular malformation that occurs primarily on the face and neck, affecting approximately 0.3% to 0.5% of newborns. The major indication for therapy in most patients, regardless of age, is the psychosocial burden due to the portwine stain. Purpose of this study is to evaluate safety and efficacy of flashlamp-pumped pulsed dye laser for pws in children. Seventy-eight children, 5months to 15years of age, with portwine stains were treated with the flashlamp-pumped pulsed dye laser with an emission wavelength of 585nm, a pulse duration of 450 microseconds and 5mm spot size. More than 75% lightening of their lesion was achieved with an average of 5.9 treatments(±2.50) in 28 patients(35.8% of all patients). Children less than five years old required fewer sessions(mean±SD, 4.63±1.71) than older children(7.15±2.33 : P<0.05). Portwine stain lesion is found more frequently on the left side of the face. There was no evidence of depressed scars, atrophy and hyperpigmentation in the treated areas. The only side effect was transient hypopigmentation which occurred in 5 patients(6.4%), indicating the relative safety of this treatment modality.

        • SCOPUSKCI등재

          CO2 레이저를 이용한 양성 피부 종양의 치료 효과

          함정희,박미연 대한피부과학회 1993 大韓皮膚科學會誌 Vol.31 No.4

          Bsckground : CO laser emiis energy in the mid portion of the infrared spectrum at a wavelengt,h of 10,600nm. The CO laser is the workhorse laser in the treatment of cuianeous disease. With water as the chromophore(light-absorbing compound), CO laser light is highy absorbed in biologic tissue. Human body tissue comprises between 75% to 90% of water. The CO laser is superficially absorbed by tissue water, with little scat ter, limiting penetration into the skin to less than 0.1 mm. The beam can be delivered with a large spot size and low power density(defocus mode) or focused tightly with great power density(focused mode). As a result : the CO laser may be used both to vaporize and to cut tissue while coagulating blood vessels, providing a relatively bloodless su gical field. Objective : The purpose of this study was to evaluate the therapeutie effect of the CO laser on benign cutaneous tumors. Methods : 114 cases of benign cutaneous tumors treated with the CO laser between October 1987 and September 1992 were subjected to detailed analysis, The CO later is Pizer Laser system(U.S.A., Ca) Model 20-C CO. The laser produces power output that ranges from 0 to 25 W of continuous wave. Spot size is variable, between 0.3mm and 2mm. Results : 1. Angiofibromas and seborcheic keratoses showed very good response(95.3%, 92.8% ). 2. Syringomas showed a good esponse(82.8%). 3. Epidermal nevus and trichovpitheliomas showed a fair response(58.5%, 60%). 4. There were hypertrophic scars(10.5%) and transient hypopigmentation. Conclusion : The Co laser was a very effective modality for the treatment of benign cutaneous tumors such as angiofibromas, seborrheic keratosis and syringomas. (Kor J Dermatol 1993; (31):502-507)

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