http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
茵蔯蒿와 韓茵蔯이 Triton WR-1339로 유도된 고지혈증 흰쥐에 미치는 영향
함인혜,정성웅,이경진,박규하,최호영 대한본초학회 2005 大韓本草學會誌 Vol.20 No.1
Objectives : In order to elucidate hyperlipidemia effect of the aerial part of A. capillaris and A. iwayomogi, an experimental study was performed on the hyperlipidemia of rats induced by Triton WR-1339. Methods : The amount of total cholesterol, triglyceride, phospholipid, HDL-cholesterol, LDL-cholesterol, AST, and ALT were measured. Results : In the hyperlipidemia of rats induced by Triton WR-1339, A. capillaris and A. iwayomogi showed decreasing effects on total cholesterol, triglyceride, phospholipid,, LDL-cholesterol. ALT, and AST. Especially, A. iwayomogi showed significant decreasing effects on total cholesterol, and phospholipid. Conclusion : According to the results, A. capillaris and A. iwayomogi need to considered for the application in hyperlipidemia
함인혜,김호현,이승재,조형권,황완균 중앙대학교 약학연구소 2001 약학 논총 Vol.15 No.-
Recently, hydrolyzed silk peptide on acid and alkaline were developed and studied on anti bacterial, cryoprotective, antioxidant, anticancer and antidiabetic activities. For the investigation of antidiabetic drug, we were elucidated the effects of enzyme hydrolyzed silk peptide on streptozotocin induced hyperglycemia, silk peptide of two different molecular weight were administrated after injection of streptozotocin (50mg/kg, ip), and blood glucose, serum triglyceride and serum cholesterol levels were determined at 4 days after streptozotocin injection. And the results were as following: 1. The blood glucose levels of streptozotocin induced hyperglycemic rats were significantly decreased by the administrations by various dose of silk peptide of Japan Products and glibenclamide and especially enzyme hydrolyzed silk peptide were showed to decrease glucose levels than another silk peptide. 2. The serum cholesterol levels of streptozotocin induced hyperglycemic rats were significantly decreased by the administrations by various dose of silk peptide of Japan Products and glibenclamide and especially enzyme hydrolyzed silk peptide were showed to decrease cholesterol levels than another silk peptide. 3. The serum triglyceride levels of streptozotocin induced hyperglycemic rats were significantly decreased by the administrations by various dose of silk peptide of Japan Products and glibenclamide and especially enzyme hydrolyzed silk peptide were showed to decrease triglyceride levels than another silk peptide.
함인혜,김일혁 중앙대학교 약학연구소 1990 약학 논총 Vol.4 No.-
To elucidate the effects of Urtica thunbergiana on streptozotocin-induced hyperglycemia, U. thunbergiana extracts were administered before and after injection of streptozotocin (45mg / kg, i.p.), and blood glucose, serum triglyceride and serum cholesterol levles were determined at 4 days after streptozotocin injection. The results were as following; 1. The blood glucose levels of streptozotocin-induced hyperglycemic rats were significantly decreased by the administrations by all of the various fractions of U. thrnbergiana and methanol extracts of herb parts were showed dose-dependently. 2. The serum total cholesterol levels were decreased by the administrations by all of the various fractions of U. thunbergiana and methanol extracts and butanol extracts of herb parts were showed dose-dependently. 3. The serum triglyceride levels decreased significantly all of the various fractions of U. thunbergiana.
함인혜,정민영,최용주,이상대,성환길,심상수,황완균 중앙대학교 약학연구소 2000 약학 논총 Vol.14 No.-
Phellinus linteus(polyporaceae) has been used as anti-cancer agent in Korea. We were studied to evaluate the anti-tumor and immunopotentiation effect of Phellinus lintenus(PL) single and mixing administration with three anti-tumor agents in folk medicines(Ulmus davidiana var japonica, Cudrania tricuspiata, and Bupleurun palcatum). Oral administraion to tumor bearing mice significantly prolonged suvival rate compared to control group with the prolongation ratio of 2% to 9%. Nitrite production of Raw 264.7 cell was increase dose-dependently
함인혜,전인주,김호현,고성권,황완균 중앙대학교 약학연구소 2002 약학 논총 Vol.16 No.-
Organic Ge and Se are very important agents of anti-cancer and preventive geriatric disease drugs so on. We were carried out the micro-elements(Ge, Se, Fe, Mg and Zn) content of several Ginsengs that were cultivated in Korea(6 regional groups) and foreign countries(Japan, China and America) by ICP analysis. From results, Ginseng of Kumsan have been appeared to high levels of Ge and Se contents in comparison with other regional samples. Especially 4 years old Ginseng appeared to high levels of Ge, Se but also Fe, Mg and Zn contents.
강장생약의 생리활성에 관한 연구(Ⅰ) : 산약의 항당뇨 효과 The Antidiabetic Effect of Dioscoreae Rhizoma
함인혜,김일혁 중앙대학교 약학연구소 1992 약학 논총 Vol.6 No.-
As one of series of traditional tonic drug in Korea, the studies were carried to evaluate the antidiabetic activities on the hyperglycemia-induced by streptozotocin in rats of Dioscorea batatas tuber. Dioscorea batatas water and methanol extracts were adiministered before and after injuction of streptozotocin(45mg/kg, i.p.)and blood glucose, serum total cholesterol and serum triglyceride levels were determined at 4th days after streptozotocin injection. The results were as follows: 1. The blood glucose levels of streptozotocin-induced hyperglycemic rats were dose-dependently decreased by administrations of all doses(100,200,400mg/kg) of water and methanol extracts. 2. The serum total cholesterol levels of streptozotocin-induced hyperglycemic rats were dose-depen dently decreased by administrations of all doses (100,200,400mg/kg) of water and methanol extracts. 3. The serum triglyceride levels of streptozotocin-induced hyperglycemic rats were dose-dependently decreased by administrations of all doses (100,200,400mg/kg) of water and methanol extracts.