형광입자들의 크기와 농도에 따른 형광 상관 분광함수 측정

한예슬,이재란,김석원,Han, Yesul,Lee, Jaeran,Kim, Sok Won 한국광학회 2012 한국광학회지 Vol.23 No.3

형광입자의 크기와 수에 따라 형광 신호의 상관함수 변화를 측정하는 형광상관분광법을 이용하여 용액 내에서 확산 운동하는 나노크기 형광 입자들의 농도와 유체역학적 반지름을 비교하였다. 시료에 사용된 나노크기 형광 입자들은 Alexa Fluor 647, 양자점, 형광 bead이고, 증류수에서 1/10, 1/100로 입자들이 들어있는 용액을 희석하여 각 입자들에 대해 3가지의 다른 농도의 시료를 준비하였다. Alex Fluor 647의 알려져 있는 확산시간을 이용하여 형광상관분광장치의 유효초점 부피를 구하고, 각 입자들의 확산계수, 크기, 희석에 따른 농도 변화를 측정할 수 있었다. 본 연구를 통해, 자체 제작된 형광상관분광장치로 임의적으로 희석된 시료들의 농도를 약 0.1 nM ~ 10 nM의 범위에서 측정할 수 있었고, 양자점의 확산계수를 $27{\pm}1{\mu}m^2/s$로 결정할 수 있었다. The concentration and hydrodynamic radius of nano-sized fluorescence particles diffusing in solution were compared by using fluorescence correlation spectroscopy (FCS), which can measure the variation of the correlation function of a fluorescence signal by size and number of particles. The used nano-sized fluorescence particles are Alex Fluor 647, quantum dots, and fluorescence beads, and three kinds of sample solutions with different concentrations were prepared by dilution to 1/10 and 1/100 with distilled water for each kind of particles. The effective focal volumes were calculated by using the known diffusion coefficient of Alexa Fluor 647 particles, and the diffusion time, number of particles in focal volume, and variation of concentration according to the dilution could be measured by the FCS system. Through this study, we determined that the concentrations of arbitrarily diluted sample solutions can be measured by a home-built FCS setup in the range of 0.1 nM ~ 10 nM and that the diffusion coefficient of the quantum dot was $27{\pm}1{\mu}m^2/s$.

대학생의 구강건강관련 삶의 질에 영향을 미치는 요인

한예슬,이근유,이주열,김혜영 한국학교・지역보건교육학회 2014 한국학교지역보건교육학회지 Vol.15 No.2

산모의 임신 2분기경 Ureaplasma urealyticum 집락이 35주 이하 미숙아에서 주수별 임상양상에 미치는 영향

한예슬,전상훈,천지영,성태정 대한신생아학회 2017 Neonatal medicine Vol.24 No.3

Purpose: The purpose of this study was to evaluate the relationship between maternal genital Ureaplasma urealyticum colonization in the second trimester and the neonatal outcomes. Methods: We studied 577 premature infants born at ≤35 weeks’ gestational age (GA) at Hallym University, Kangnam Sacred Heart Hospital from January 2008 to December 2014. Maternal vaginal specimens were collected and polymerase chain reaction and/or culture tests were done in the second trimester of pregnancy. The subjects were divided into 2 groups: a Uu colonization-positive group (UU) and a Uu-negative (control) group. Subgroup analyses were performed in extremely premature (23–28 weeks’ GA) and premature (29–35 weeks’ GA) infants. Various clinical outcomes were compared. Results: Of 577 preterm infants, 311 were delivered with maternal Uu infection (UU, 53.9%). Mean GA (30.0±3.6 weeks vs. 31.0±3.7 weeks, P=0.010) and birth weight (1,685.6±680.4 g vs. 1,932.7±733.1 g, P=0.003) were lower in the UU group than in controls. However, there were no significant differences in GA and birth weight in extremely premature group. Premature labor (P=0.002) and histological chorioamnionitis (P=0.032) was significantly more common in the UU group, especially in mothers who delivered in third trimester (29–35 weeks’ GA). In particular, the incidence of moderate-to-severe BPD was statistically higher in UU extremely premature group (60.8% vs. 32.2%) (P=0.001). Conclusion: Maternal colonization with Uu was associated with an increase in premature delivery and lower birth weights. Moderate-to-severe BPD was more common in premature infants born at ≤28 weeks’ GA with maternal Uu colonization.

약한 교류 자기장을 이용한 광학 매질의 Faraday 회전 측정

한예슬,이재란,김석원 한국물리학회 2010 새물리 Vol.60 No.1

Faraday rotation, the phenomenon of polarization rotation, occurs when a magnetic field is applied to a dielectric material along the propagation direction of a light beam. In this study, the Faraday rotation was identified and the Verdet constants were measured for materials such as BK7 glass, Nd:glass, and ruby under an AC magnetic field by using a simple device with a linearly-polarized He-Ne laser with a 632.8-nm wavelength as a light source. The results show that the Verdet constants of BK7 glass, Nd:glass, ruby (o-ray), and ruby (e-ray) were (2.302±0.300) ˚/cm·T, (2.089±0.059) ˚/cm·T, (0.020±0.008) ˚/cm·T, and (0.019±0.006) ˚/cm·T, respectively. In this study, it was found that the Faraday rotation under a small could be measured precisely even under the relatively small magnetic field induced by the application of a low current to a solenoid wound coil and that the magnetic properties of BK7 glass and Nd:glass, which include silica glass and ruby, with birefringence were compared and analyzed. 유전체 매질에 빛의 진행 방향으로 자기장이 인가될 때 빔의 편광방향이 회전하는 Faraday 회전 현상이 나타는데, 비교적 간단한 장치 구성으로 파장이 632.8 nm이고 선편광된 He-Ne 레이저 광원에서 BK7 유리, ruby, Nd:glass와 같은 매질에 대해 교류 자기장에서의 Faraday 회전 현상을 확인하고 각 매질의 자기광학 상수인 Verdet 상수를 측정하였다. 측정결과 BK7 유리, Nd:glass, ruby(o-ray), ruby(e-ray)의 Verdet 상수는 각각 2.256±0.036 ˚/cm·T, 2.162±0.004 ˚/cm·T, 0.020±0.008˚/cm·T, 0.019±0.006 ˚/cm·T로 측정되었다. 본 연구를 통해 코일에 낮은 전류를 흘려서 비교적 작은 자기장에서도 Faraday 회전을 정밀하게 측정할 수 있음을 확인하였고, sillica glass가 포함된 BK7 유리와 Nd:glass, 복굴절 매질인 ruby의 자기적 특성을 비교․분석할 수 있었다.

COVID-19로 인한 마스크 착용이 구강건강행동에 미치는 영향

한예슬,오한나 한국엔터테인먼트산업학회 2023 한국엔터테인먼트산업학회논문지 Vol.17 No.6

The purpose of this study was to understand the changes in oral health behavior caused by mask wearing due to the COVID-19 pandemic and to confirm the influencing factors. The collected data used a self-administered questionnaire collected from 254 adults in their 20s to 60s living in Jeollabuk-do. SPSS Windows program 18.0 was used for the analysis and the statistical significance level was chosen at 0.05. Independent sample t-test and one-way ANOVA were performed to compare self-oral health symptoms by general characteristics or oral health behaviors. Changes in oral care product use before and after the COVID-19 epidemic were analyzed using a matched sample t-test. A logistic regression analysis was performed to identify factors influencing changes in positive oral health behaviors. Studies have shown that oral fern fluid was used more frequently post-COVID-19 than pre-COVID-19. In addition, factors that cause positive changes in oral health behavior were shown to be the degree of self-recognition of oral health symptoms, oral health education behavior, brushing behavior, and use of oral care products. Therefore, oral health education focused on oral care products will have to be implemented in order to take positive actions to create a healthy mouth.

에코세대의 라이프스타일과 주관적 심리건강 및 구강건강상태와의 연관성

한예슬,박소영 보건의료산업학회 2020 보건의료산업학회지 Vol.14 No.4

Objectives: The purpose of this study is to identify the lifestyle of the eco-generation and identify general factors, subjective psychological health, and oral health-related factors as related variables to assist in psychological health care and oral health projects and education. Methods: A survey was conducted on 192 patients, guardians, and simple visitors from 1979-1992 who visited a dental clinic in Seoul. Results: As a result of this study, the eco-generation has the highest health-seeking lifestyle and the lowest social-supporting lifestyle. Subjective psychological and oral health status were the most influential factors in all five lifestyle areas of the eco-generation. Conclusions: We examined the lifestyle and psychological and oral health related factors of the eco-generation, which is useful in that it has provided theoretical and practical implications for the eco-generation to realize a more positive lifestyle.

Successful Management of Severe Peripheral Tissue Ischemia after Arterial Catheterization in Micro Preemies using Humidification & Topical Nitroglycerin

한예슬,송송이,성태정,천지영 대한신생아학회 2017 Neonatal medicine Vol.24 No.4

Micro preemies usually undergo arterial catheterization for frequent blood pressure monitoring and blood sampling. Peripheral tissue injury associated arterial catheterization is a well-described morbidity observed in neonates. Despite the potential permanent disability associated with this complication, the currently available therapeutic options remain limited. We report a unique case of a preterm infant who developed severe tissue ischemia after arterial catheterization of the radial artery and was successfully treated using extensive humidification and topical nitroglycerin ointment application over an extended period (36 days) until complete clinical recovery.

치약선택기준에 따른 구매만족, 재구매 의도 및 권유 의사 분석

한예슬 ( Ye Seul Han ),이지은 ( Ji Eun Lee ),문학진 ( Hak Jin Moon ),임순연 ( Soon Ryun Lim ),조영식 ( Young Sik Cho ) 한국치위생과학회 2015 치위생과학회지 Vol.15 No.1

The purpose of this study was to understand the buying behavior characteristics of the customers. Also, it was intended to provide information to provide companies marketing strategy. The criteria of purchasing toothpaste was to try to understand the impact on satisfaction, recommendation and repurchase Intention. The study was surveyed 248 customers who re-buy the toothpaste in oral care products showroom at university dental hospital. Statistical analysis was performed using PASW Statistics 18.0 and AMOS 18.0 at the 5% significance level. The results were as follows: ‘Flavor’, ‘Price’, ‘Brand’, ‘Function’, ‘Design’ of toothpaste and satisfaction showed a positive correlation. Satisfaction and repurchase intention, Recommendation showed a positive correlation. Selection criteria that affect the satisfaction when customers buy toothpaste, ‘Function’ was the greatest and others became the order of the ‘Brand’, ‘Flavor’, ‘Price’. Satisfaction affect the recommendation and repurchase Intention. If customers are satisfied with the toothpaste products, showed the Repurchase Intention, have shown opinion that is willing to recommend this product to others. Therefore, dentistry and manufacturers of toothpaste must share a lot of information about toothpaste with customers. Also, information, function, flavor of toothpaste as well as other oral care product, It will be a needed the continuing research and development.

동기면담을 적용한 구강 관리 프로그램의 효과

한예슬 ( Ye Seul Han ),배현숙 ( Hyun Sook Bae ),조영식 ( Young Sik Cho ) 한국치위생과학회 2014 치위생과학회지 Vol.14 No.3

The purpose of this study is to use basic data of dental hygiene curriculum with a new technique called motivational interviewing of communication skill to demonstrate the effectiveness of the method of oral health care. In this study, we performed oral health care program that has been made in dental hygiene department to university students. It was assigned to the control group and 66 and 32 experimental group based on the date of the first visit time. It conducted motivational interviewing of a total of three times in the experimental group. The analytical results of the measurements obtained in the oral examination and questionnaires. The results were as follows: The experimental group measured value was reduced after the intervention compared to before the PSR to evaluate the state of periodontal, gingival index, calculus index, plaque control record(PCR; O’Leary plaque index), simple plaque scor of Quantitative Light Induced Fluorescnece Digital measurement value (p<0.05). Experimental group decreased more and more the result of changes in the reduction of the average of the PCR. But control group was reduced to 3 weeks and increased back to the middle 16 weeks. There was also support interaction between the measurement point and the groups (p<0.05). Re-visit adherence of fit, 12.1% in the control group, the experimental group was 43.7% in the period of participation in the oral health care program. Thus, visit adherence of the experimental group was higher. In this study, a group that has motivational interviewing, It was able to confirm the improvement of oral health state. Discussion of the motivational interviewing can be applied to oral health care program.

회전법과 변형스틸맨법의 치면세균막 감소 효과 비교

한예슬 ( Ye Seul Han ),임순연 ( Soon Ryun Lim ),조영식 ( Young Sik Cho ) 한국치위생과학회 2012 치위생과학회지 Vol.12 No.6

본 연구는 회전법과 변형 스틸맨법간의 치면세균막 감소 효과를 비교하기 위하여 천안 소재 대학교 31명의 대학생을 대상으로 무작위 배정한 순수실험을 설계하여 치면세균막관리프로그램을 시행한 결과 다음과 같은 결과를 얻었다. 1. 중재 전후에 따른 각 잇솔질의 치면세균막 관리를 비교한 결과 중재 전에 측정한 SPS Score와 □R30에서 두 잇솔질 방법간의 차이는 나타났으나(p<0.05), 나머지 측정값들과 중재 후의 측정값에서 유의한 관련성을 보이지 않았다(p>0.05). 2. 각 잇솔질 방법에 따른 중재 전 후의 치면세균막 관리를 비교한 결과 PCR, QLF-PCR, □R30, □R60j에서 회전법과 변형 스틸맨법 집단은 통계적으로 유의한 차이가 있었다(p<0.05). 또한, 회전법보다 변형 스틸맨법 집단에서 치면세균막 지수는 더 큰 감소를 보였고,잇솔질 교육 중재를 실행한 후 치면세균막 지수가 감소하는 것으로 나타났다. 3. PCR과 QLFD 촬영 측정값의 관계에서 PCR과 육안검사 QLF-PCR의 관계, SPS Score와 그 하위 척도 □R값들의 상관관계는 보였으나, PCR와 QLF값의 상관관계는 보이지 않았다. 이상의 결과를 종합해보면, 회전법과 변형스틸맨법의 치면세균막 관리 효과는 통계적으로 유의하지 않았으나, 회전법보다 변형 스틸맨법 집단에서 치면세균막 감소차이는 더 큰 것으로 확인되었고, 잇솔질 교육을 샐행함으로써 치면세균막 지수가 감소하는 것으로 나타났다. The purpose of this study was to use basic data of dental hygiene curriculum by comparing the rolling method and modified stillman method. Plaque measurement method, Q-ray examination of the clinical utilization value shall review. True experimental design is randomized controlled trial to the intervention group and the control group. Measurements are plaque control record (PCR; O`Leary index) measurements and Quantitative Light induced fluorescnece Digital (QLFD) shooting as a pre-test was conducted. Intervention group is modified stillman method, control group is rolling method. Intervention after 5 weeks, PCR measurement and QLFD shooting was carried out as a post-test. Rolling method and modified stillman method plaque reduction did not differ. Intervention before and after the results of the comparison showed reduced plaque score after brushing law education. Also, Plaque reduction differences were more pronounced modified stillman method than rolling method. PCR and QLFD values of the correlation was not confirmed but SPS Score and the lower value of the ΔR value of the correlation. Plaque of maturity tooth that are not observed visually.