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Clinical Outcomes of Cryopreserved Arterial Allograft Used as a Vascular Conduit for Hemodialysis
하태용,김영훈,장재원,박양순,한영진,권현욱,권태원,한덕종,조용필,이성규 대한의학회 2016 Journal of Korean medical science Vol.31 No.8
This single center cohort study aimed to test the hypothesis that use of a cryopreserved arterial allograft could avoid the maturation or healing process of a new vascular access and to evaluate the patency of this technique compared with that of vascular access using a prosthetic graft. Between April 2012 and March 2013, 20 patients underwent an upper arm vascular access using a cryopreserved arterial allograft for failed or failing vascular accesses and 53 using a prosthetic graft were included in this study. The mean duration of catheter dependence, calculated as the time interval from upper arm access placement to removal of the tunneled central catheter after successful cannulation of the access, was significantly longer for accesses using a prosthetic graft than a cryopreserved arterial allograft (34.4 ± 11.39 days vs. 4.9 ± 8.5 days, P < 0.001). In the allograft group, use of vascular access started within 7 days in 16 patients (80%), as soon as from the day of surgery in 10 patients. Primary (unassisted; P = 0.314) and cumulative (assisted; P = 0.673) access survivals were similar in the two groups. There were no postoperative complications related to the use of a cryopreserved iliac arterial allograft except for one patient who experienced wound hematoma. In conclusion, upper arm vascular access using a cryopreserved arterial allograft may permit immediate hemodialysis without the maturation or healing process, resulting in access survival comparable to that of an access using a prosthetic graft.
하태용,박태정 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.0
The bovine viral diarrhea virus (BVDV) is the most fatal disease for cattle, which is high lethality virus and has been associated with inapparent infection. The high lethality for the cattle would occur economical losses and needs to detection method for BVDV as a prevention of cattle. In this study, the dot blotting method was introduced to develop the detection which is useful and portable method. In addition, this study was applied to the signal enhancement by using copper nano-polyhedral shell (CuP) overgrowth in order to improve the signal of gold nanoparticles (AuNPs), has an advantage for the development of naked-eye-based highly sensitive and selective detection against BVDV. Consequently, by using the signal enhancement method for the coated AuNPs with affinity peptide indicated a low detection limit of 0.19 copies/mL. Reducing infection syndromes, and the biosensor will have a potential as a new biosensing platform for point-of-care testing by applying much more fields.