韓國 어린이들의 恐怖心에 關한 硏究

崔惠貞 梨花女子大學校 文理大學 家政學部 1965 家政 Vol.- No.13

식은 땀을 호소하는 진행성 암 환자에서 비스테로이드성 항염증 제제를 이용한 치료

최혜정,송하나,강정훈,Choi, Hye Jung,Song, Haa-Na,Kang, Jung Hun 한국호스피스완화의료학회 2016 한국호스피스.완화의료학회지 Vol.19 No.4

목적: 진행성 암 환자에서 발열이 동반되지 않은, 암성 발한에서 NSAID (non-steroid anti-inflammatory drug) 치료 효과를 알아보고자 함이 목적이다. 방법: 다음과 같은 조건을 만족하는 환자를 대상으로 후향적으로 의무 기록을 조사하였다. 1) 수술적 절제나 항암방사선 치료로 완치가 불가능한 진행성 암 환자 2) 숫자평가등급 4점 이상의 식은 땀을 호소하며 발열이 동반되지 않은 환자 3) 식은 땀의 원인이 될 만한 감염이 없고, 마약성 진통 및 호르몬 차단제를 현재 최근 1개월 이내 새롭게 사용하지 않는 환자 4) 식은 땀 치료를 위해 NSAID를 사용하고, NRS 평가가 치료 전 후 시행한 환자. 결과: 총 13명의 환자가 등록되었다. 남자가 9명(69%)이었고, 평균 59세(범위: 50~71)였다. 암종별 빈도는 담도암, 췌장암, 위암, 전립선암 순이었다. 치료 전 환자들의 식은 땀은 평균 NRS 6.5 (최소값: 4, 최대값: 10) 이었고, 치료 후에는 NRS 1.9 (최소값: 0, 최대값: 5)이었다. 평균 추적 관찰 기간은 9.1일이었다. 결론: 진행성 암 환자에서 열이 동반되지 않은 중등도 이상의 식은 땀 환자에서 NSAID는 효과적인 치료방법이다. Purpose: Advanced cancer may accompany cold sweat as paraneoplastic symptom. Few studies have been performed on the efficacy of non-steroid anti-inflammatory drug (NSAID) in advanced cancer patients who sweated without fever. Methods: To select study participants, medical records were retrospectively reviewed for patients who satisfied the following criteria: 1) incurable, advanced solid cancer; 2) Cold sweating of 4 or higher on the numeric rating scale (NRS) 4; 3) No evidence of infection or hypoglycemia; 4) No newly started opioid or anti-hormonal agents within one month; 5) NSAID prescription for the management of cold sweating and 6) Documented NRS information before and after NSAID administration. Results: A total of 13 patients were selected after excluding four patients due to lack of NRS information or fever. The mean age was 59 years old (range: 50~71), and nine patients (69%) were male. Bile duct cancer was the most common primary tumor followed by pancreatic cancer, gastric cancer and prostate cancer. The mean NRS of cold sweating dropped from baseline 6.5 (min-max: 4~10) to 1.9 at the follow-up assessment (min-max: 0~5). The mean follow-up period was 9.1 days (range: 2~30 days) from NSAID treatment to assessment. Conclusion: NSAID was effective medication for management of sweating without fever in patients with advanced cancer.

우울증

최혜정 약업신문사 2001 의약정보 Vol.2001 No.4

대상포진상 편평태선 1예

최혜정,정철수,박철종 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.2

Zosteriform lichen planus is a rare variant of lichen planus, which can be differentiated from linear lichen planus by not linear, but zosteriform distribution. The pathogenesis of zosteriform lichen planus has been most commonly described as a Koebner phenomenon. We, herein, present a case of zosteriform lichen planus in a 69-year-old man with pruritic, grouped, violaceous papules in zosteriform arrangement on his left flank for 3 months. He had no history of any previous skin disease. Histopathologically, the papule showed characteristic findings consistent with lichen planus. (Korean J Dermatol 2004;42(2):202~204)

Pseudomonas sp. BCNU106에 의한 indigo 및 관련 화합물의 생산

최혜정,이민아,문자영,김동완,이영근,정영기,주우홍 한국생명과학회 2005 한국생명과학회 심포지움 Vol.45 No.-

퇴행성신경질환과 운동

최혜정 대한운동사협회 2008 대한운동사협회 운동사대회자료집 Vol.2008 No.-

흰쥐에서 streptozotocin에 의해 유도된 당뇨병에 대한 운동과 melatonin의 효과

최혜정,장은주,김유현,김기진,문교철 대한스포츠의학회 2005 대한스포츠의학회지 Vol.23 No.2

The effects of melatonin and exercise on diabetes mellitus induced by streptozotocin in male Sprague-Dawley rats were studied. Diabetes was induced by the intraperitoneal injection of 65 mg of streptozotocin per kg of body weight. To know the effect of melatonin, a dose of 10 mg of melatonin per kg of body weight was administered intraperitoneally. And to know the effect of exercise, rats were performed exercise by a treadmill running at the speed of 10 m/minute, 8% of slope, for 60 minutes in a day for 1 week. The parameters including the levels of blood glucose, hemoglobin A1C, and malondialdehyde analysed to evaluate diabetic state and the degree of lipid peroxidation by oxygen free radicals. The injection of streptozotocin caused significant increases in the levels of blood glucose, hemoglobin A1C and malondialdehyde. Melatonin and exercise reduced significantly the levels of blood glucose, hemoglobin A1C and malondialdehyde which were increased by streptozotocin injection. When the effect of melatonin and exercise in the diabetic rats was compared the exercise was more effective for normalizing the parameters which were changed by streptozotocin injection than melatonin. These results may suggest that melatonin and exercise are effective the oxidative damage in the diabetes induced by streptozotocin. Exercise is more protective for diabetes mellitus than melatonin.

Morphological characterization and molecular phylogenetic analysis of Dolichospermum hangangense (Nostocales, Cyanobacteria) sp. nov. from Han River, Korea

최혜정,주재형,김주환,Pengbin Wang,기장서,한명수 한국조류학회I 2018 ALGAE Vol.33 No.2

Dolichospermum is a filamentous and heterocytous cyanobacterium that is one of the commonly occurring phytoplanktons in the Han River of Korea. Morphological observations led to the identification of D. planctonicum-like filaments in seasonal water samples. In the present study, we successfully isolated these filaments using culture methods, and examined its morphology using light and scanning electron microscopy. The morphology of the D. planctonicum-like species differed from that of typical D. planctonicum; it had thin cylindrical-shaped akinetes, which were narrower towards the ends than at the center. This morphology is firstly described in the genus Dolichospermum. In addition, the akinetes in the filament developed solitarily and were distant from the heterocytes. Phylogenetic analysis of the 16S rRNA sequences showed that our Dolichospermum clustered with D. planctonicum and D. circinale, which have coiled trichome. However, phylogenetic analysis of the gene encoding rivulose-1,5-bisphosphate carboxylase (rbcLX) clearly separated our species from other Dolichospermum, forming a unique clade. Additionally, structures of D. planctonicum and D. hangangense strains were different type in Box-B and V3 region. These results demonstrated that the new Dolichospermum species was unique in morphology and molecular traits. Therefore, we propose this to be a new species belonging to genus Dolichospermum with the name Dolichospermum hangangense sp. nov.

성찰일지 분석을 통한 간호대학생의 보건소 실습 경험(현상학적 연구)

최혜정 대한통합의학회 2019 대한통합의학회지 Vol.7 No.4

Purpose : The purpose of this study is to understand the experiences of nursing students in clinical practice at public center through self- reflection Subjects : The 110 students in the 3rd grade, practice with two public center in p city and k city. Among them, 53 male and female university students who were practice in k city were selected. The study participants were 16male (30.2%) and 37 female students.(69.8%). Methods : Data were analyzed through self-reflection of 53 undergraduate nursing students after clinical practice. Results : On the basis of these data, most students think public health center provides much more services for community people than they usually have thought. They evaluate health center program highly, and want to be community health nurse. For the first time, they come to know the manpower of public health nurses is very important. Especially their emotion at public health center is quite different from emotion at the other clinics. The environment of health center makes them more comfortable and not stressful, Generally, they were satisfied with the practice of public health center. Conclusion : On the basis of these findings, following recommendations are to be made. Experiences at public health center are important part of nursing student education. I suggest the research of the experience of the practice at the public health center should proceed to other research methods other than the reflection journal, and follow - up study of experience of practice at public health center should be attempted according to the level of self-reflection. 간호학과 학생들의 보건소 실습 경험에 대해 성찰일지 내용을 현상학적으로 분석한 결과 ‘보건소 인식의 변화’, ‘지역사회 간호사 역할의 재발견’, ‘정서적 경험’, ‘전문적 경험’, ‘실습체계’, ‘의사소통’, ‘새로운 발견’의 7개의 범주와 ‘부정적 선입견’, ‘새로운 내용을 알게 됨’, ‘보건소의 중심 역할’ ‘새로운 프로그램 창조자’, ‘기대감’, ‘여유로움’, ‘두려움과 불안’, ‘아쉬움’, ‘당황함’, ‘친절함’, ‘감사함’, ‘무시당함’, ‘노인인구와 노인간호사업의 이해’, ‘독거노인들의 현실이해’, ‘건강증진사업의 이해’, ‘다양한 지원사업의 발견’, ‘실습시간 이용의 부적절’, ‘실습시기의 조정’, ‘현장지도자 부족’, ‘노인과 의사소통 기회’, ‘다양한 프로그램 참가’등 21개의 주제가 도출되었다

면세점 유니폼에 대한 자기이미지와 고객지향성 간 영향관계

최혜정,양정임 관광경영학회 2014 관광경영연구 정기학술 세미나 Vol.2014 No.08