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      • 옵션이론을 통한 리츠의 가치평가

        최진하,원재웅,전재범 한국지역개발학회 2018 한국지역개발학회 학술대회 Vol.2018 No.6

        Real estate investment trusts(REITs) have been witnessing a steady growth for the past 16 years since they were introduced in korea in 2001. However, in reality, the individual investor has limited opportunities to invest in REITs for various reasons, including excessively stringent regulations and lack of investment-related information due to non-uniform accounting standards. The fact that the capital can be withdrawn only at maturity also discourages investments, increasing concerns over potential capital recovery. Moreover, the growth rate of the REIT industry in Korea has been relatively lower than in other countries. This is because most AMC(Asset Management Companies)that act as the actual operators of REITs are small in their size, given that one company has only one underlying asset. To resolve these issues, this study seeks to structure financial model by modifying theories relevant to financial economics and option pricing. This, in turn, allows premature liquidation valuation alleviate the risk of capital recovery. This model facilitates AMCs to allow individual investors to decide capital recovery time and provide them with value-related information.

      • KCI등재후보

        An Atto-molar Detectable Colorimetric DNA Biosensor based on Enzyme Amplification Method

        최진하,구유경,김봉래,오병근 한국바이오칩학회 2009 BioChip Journal Vol.3 No.3

        In this study, we report on the rational design of a nano-complex that consists of silica nanoparticles (SiNP), probe DNA and horseradish peroxidase (HRP) for the detection of target DNA. SiNPs were modified to probe DNA and streptavidin for the subsequent binding of biotinylated HRP enzymes. The localized binding of multiple HRP enzymes to the SiNP was used to amplify the signal of the target probe. Afterwards, magnetic microparticles (MMP) were functionalized with capture DNA and used in a sandwich reaction with the target DNA. The MMPs containing the target DNA were then bound to SiNPs via DNA hybridization. The interaction forces that resulted from the DNA hybridization between the functionalized MMP containing target DNA and SiNPs was use to separate unbound MMP; a agnetic field was used to effectively remove unbound MMP. For detection of DNA, we exploited the reaction of HRP enzyme immobilized on silica probes with tetramethylbenzidine (TMB) that is a substrate of HRP, followed by stopping the reaction with 2M H2SO4. The resulting end products were analyzed by UV-vis spectroscopy. Using this method, we could detect down to 500 aM of target DNA a short time. This method is very simple and highly sensitive relative to established DNA biosensors and can be used to detect specific DNA markers associated with tumors, bacterial infections or other disease.

      • KCI등재

        H.264/AVC의 효율적인 전 영역 움직임 추정을 위한새로운 움직임 벡터 예측 방법 제안

        최진하,이원재,김재석 대한전자공학회 2007 電子工學會論文誌-SP (Signal processing) Vol.44 No.3

        H.264/AVC has many repeated computation for motion estimation. Because of that, it takes much time to encode and it is very hard to implement into a real-time encoder. Many fast algorithms were proposed to reduce computation time but encoding quality couldn't be qualified. In this paper we proposed a new motion vector prediction method for efficient and fast full search H.264/AVC motion estimation. We proposed independent motion vector prediction and SAD share for motion estimation. Using our algorithm, motion estimation reduce calculation complexity 80% and less distortion of image (less PSNR drop) than previous full search scheme. We simulated our proposed method. Maximum Y PSNR drop is about 0.04 dB and average bit increasing is about 0.6% 본 논문은 영상 부호화 표준인 H.264/AVC에서 중요한 과정인 움직임 추정에서 효율적인 전 영역 추정을 위해 인접 서브 매크로 블록과 독립적인 새로운 움직임 예측 방식을 제안한다. H.264/AVC는 높은 압축 효율을 위해 H.264/AVC에서는 움직임 추정 과정에서 7가지의 다양한 가변 블록을 사용 한다. 그러나 다양한 가변 블록으로 인해 반복적인 연산이 많아지고 복잡해져 움직임 추정에 많은 시간이 소요된다. 이로 인해 실시간 인코딩이 어려워지게 되었다. 이를 해결하기 위해 많은 고속 움직임 추정 방식이 제안되었으나 전 영역 움직임 추정에 비해 영상의 품질(PSNR)이 떨어지고 비트 수가 증가하게 된다. 제안된 독립적 움직임 예측 방식과 SAD 값을 공유하여 움직임 추정을 수행할 경우 기존 전 영역 탐색에 비해 반복적인 연산 양이 80%정도 감소하게 된다. 또한 연산양이 감소됨에도 불구하고 시뮬레이션 결과 Y PSNR은 최대 0.04 dB 이하의 변화만을 가져왔고 인코딩된 Bit 수는 평균적으로 약 0.6% 정도만 증가하였다.

      • KCI등재

        뇌동맥 경화증 진단에서 삼차원 비약시간기법을 이용한 자기공명혈관조영술과 조영증강 자기공명혈관촬영술의 비교 연구

        최진하,임수미,김유경 대한영상의학회 2011 대한영상의학회지 Vol.64 No.3

        Purpose: We compared diagnostic performance of 3D Time of flight MRA with contrast-enhanced MRA to detect and quantify intracranial atherosclerotic occlusive disease. Materials and Methods: From April 2007 to December 2009, we enrolled 95 patients with clinically suspected intracranial atherosclerotic steno-occlusive disease who had undergone 3D TOF-MRA and CE MRA at 1.5T or 3T with DSA. Two radiologists analyzed the post-processed images using a maximum intensity projection. Intracranial vessels were categorized as distal internal carotid artery, middle cerebral artery or vertebrobasillar artery. We graded the degree of stenosis and assigned subjects to one of three groups: low grade occlusion (<50%), high grade occlusion (50-99%) and complete occlusion. Using the McNemar test, we compared the results of CE MRA with those of 3D TOF for detecting >50% stenosis using DSA as a reference standard. Results: CE MRA had 94.2% sensitivity, 88.1% specificity, 51% positive predictive value, 99.1% negative predictive value and 88.8% diagnostic accuracy for detecting >50% stenosis; In contrast, 3D TOF-MRA showed 94.2% sensitivity, 91.6.1% specificity, 59.8% positive predictive value, 99.1% negative predictive value and 91.9% diagnostic accuracy. Sensitivity and specificity of CE MRA were not significantly different than sensitivity and specificity of 3D TOF MRA (p >0.05). Conclusion: 3D TOF-MRA provides comparable diagnostic performance with CE-MRA for diagnosis intracranial atherosclerotic disease. 목적: 뇌혈관 협착 및 폐색 질환 진단에 삼차원 비약시간 자기공명혈관촬영술(3D Time of flight Magnetic Resonance Angiograhpy, 이하 3D TOF MRA) 과 조영증강 자기공명혈관촬영술(Contrast enhanced MRA, 이하 CE MRA)의 진단적 가치를 비교하고자 하였다. 대상과 방법: 2007년 4월부터 2009년 12월까지 뇌혈관 협착 증상이 있거나 의심되어 뇌자기공명혈관촬영술을 시행하고 고식적 혈관조영술을 함께 시행한 95명 환자를 대상으로 하였다. 영상분석은 두 명의 영상의학과 의사가 최대강도투사기법으로 재구성한 3D TOF MRA와 CE MRA 영상을 분석하였다. 두개강 내 혈관은 원위부 내경동맥, 중대뇌동맥, 척추바닥뇌동맥으로 나누어 혈관 직경이 50%까지 좁아져 있으면 저등급 협착, 50% 이상 99%까지 고등급 협착 그리고 폐색 3단계로 기록하였다. 이후 혈관조영술을 표준지표로 설정하고 McNemar test를 이용하여 50% 이상의 고등급 및 폐색 진단에서 3D TOF MRA와 CE MRA의 민감도(sensitivity)와 특이도(specificity)를 비교하였다. 결과: 50% 이상의 고등급 및 폐색 진단에서 CE MRA의 민감도, 특이도, 양성예측도, 음성예측도, 정확도는 94.2%, 88.1%, 51%, 99.1%, 88.8%이며, 3D TOF MRA는 94.2%, 91.6%, 59.8%, 99.1%, 91.9%였다. CE MRA와 3DTOF MRA의 민감도와 특이도는 통계적으로 유의한 차이를 보이지 않았다(p > 0.05). 결론: 뇌혈관 협착이나 폐색의 진단에서 3D TOF MRA는 CE MRA와 대등할 만한 진단적 성취를 제시하였다.

      • KCI등재후보

        환경갈등의 발생원인과 구조분석-계룡산자연사박물관 건립사례를 중심으로

        최진하,이진헌 한국환경정책학회 2004 環境政策 Vol.12 No.2

        This study were purposed to do the causing factors and structure analysis about the environmental conflicts generated during the construction of Natural History Museum at Gyeryong-Mountain. We surveyed 95 persons who were Government Officers and environmental NGO's in Chungnam-do, with questionnaire on August 2003.We analyzed factor I, II, and III from 25 environmental conflict causes. The explanatory power were 33.1% at factor I, 23.6% at factor II and 14.5% at factor III, respectively. Factor I included 12 conflict causes, which has the communality of ‘Administrative Procedures. Factor II included 5 conflict causes, which has the communality of ‘Environment-Economy'. Factor III included 5 conflict causes, which has the communality of ‘Political Factor'. Chronbach's α were 0.9271 at factor I, 0.9316 at factor II, and 0.8710 at factor III, respectively.The responses of females, 20 ages and NGO's were very negative at all factors, such as ‘Administrative Procedures Factor', ‘Environment-Economy Factor', and ‘Political Factor'. Their response were significantly different between 20 ages and 50 ages(p<0.05), and between Government Officers and NGO's(p=0.000). The multiple regression model of conflict level with factor I, II and III was Y=4.526 - 0.466(factor I) - 0.272(Factor II) - 0.118(factor III)(R=0.478).We concluded that the first major factor was ‘Administrative Procedures Factor', and next were ‘Environment-Economy Factor' and ‘Political Factor' at conflict causes generated during the construction of Natural History Museum at Gyeryong-Mountain. And also depending to be NGO's 20 ages-female, their response were negative.

      • KCI등재

        Nanomaterial-Based In vitro Analytical System for Diagnosis and Therapy in Microfluidic Device

        최진하,이재원,오병근 한국바이오칩학회 2016 BioChip Journal Vol.10 No.4

        Nanomaterials have several advantages in detecting several biomaterials and in enhancing signals and their inherent effects. Thus, they have been widely applied in the biomedical fields such as biosensor and cancer therapeutics. Recently, the development of microfluidic technology has led to superior biological analysis systems to detect biomarkers related to diseases or serve as in vitro drug screening platform. In a microfluidic device, samples could be analyzed more accurately, rapidly and simply. In addition, it is possible to culture the cells in these microfluidic devices, therefore making the in situ analysis of secretomes easy. Nanomaterials can be easily applied in the microfluidic channels as capturing and signaling materials in order to improve the sensing or therapeutic property. In particular, nanomaterial integrated microfluidic cell culture model can replace in vivo disease models for nanotherapeutics screening. In this review, nanomaterial-based sensing systems, which include diverse organic and inorganic nanoparticles, are introduced with specific examples, including microfluidics integrated systems. Moreover, microfluidics derived nanomaterial analytic systems as in vitro 2 or 3-dimensional (2D or 3D) cell culture platform will be presented. We also highlight the future perspectives of the microfluidic-driven system as highly sensitive total analysis system with functional nanoparticles.

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