와송 추출물의 면역기능 개선 효과 및 안전성 연구: 단일기관, 무작위배정, 이중눈가림, 위약대조 비교, 임상연구 프로토콜

최진용,최준용,임현우,김정,김소연,한창우,Choi, Jin Yong,Choi, Jun Yong,Lim, Hyun Woo,Kim, Jeong,Kim, So Yeon,Han, Chang Woo 대한한의학방제학회 2017 大韓韓醫學方劑學會誌 Vol.25 No.2

Objectives : This trial aimed to determine if Wasong (Orostachys japonicus) extract can enhance immune system and is safe enough to be approved as a health functional food. Methods : Total 62 people, aged 45 and older, will be recruited to participate in a randomized, double-blind, placebo-controlled clinical trial. This study will compare Wasong extract and placebo. Wasong group will take 1g of Wasong extract, once a day, for 8 weeks. Placebo group will take 1g of crystalline cellulose as placebo, once a day, for 8 weeks. Outcomes will be measured at the baseline, the end of 4th week, and 8th week. Primary outcomes are the ratio of NK cells/total lymphocytes and the ratio of T-helper cells/T-suppressor cells. Secondary outcomes are total white blood cell count, the ratio of neutrophils, lymphocytes, and monocytes in total leukocytes, the ratio of total T cells, T-helper cells, T-suppressor cells, and B cells to lymphocytes, the amount of blood IgM, IgG, IgA, and cytomegalovirus (CMV) IgG, and blood metabolite target &global analysis. Results : This trial was approved by institutional review board of Pusan National University Korean Medicine Hospital (registry number: 2016006), and registered in Clinical Research information Service, one of WHO International Clinical Trials Registry Platform (registry number: PRE20161006-002). Recruitment opened in February 2017 and is supposed to be completed by August 2017. The result is expected to be published by June 2018. Conclusion : This trial will provide clinical information to determine the efficacy and safety of Wasong in enhancing immune system of middle-aged and older people.

전기 손상으로 인한 두통 환자의 한방치료 증례 보고

최진용,배고은,심소현,서희정,서형범,최준용,권정남,이인,홍진우,윤영주,박성하,김소연,한창우,Choi, Jin-yong,Bae, Go-eun,Shim, So-hyun,Seo, Hee-jeong,Seo, Hyung-bum,Choi, Jun-Yong,Kwon, Jung-nam,Lee, In,Hong, Jin-woo,Yun, Young-ju,Park, Seong- 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.2

A 58-year-old woman came into our clinic with headache, dizziness, and malaise after an electrical injury. Even though she received conventional treatment about five weeks after the injury, the symptoms did not improve, and she decided to undergo traditional Korean medicine treatment. During a 20-day hospital stay with acupuncture and herbal medicine, the symptoms were reduced to about half, and after six months of further treatment in the outpatient clinic, there was no pain during the day and only moderate headaches occurred intermittently after intense physical activity. As far as we know, this is the first report to treat the aftereffects of electrical injury with traditional Korean medicine treatment. Hence, here we tried to fully describe and announce the detailed progress of the patient through this report.

항암화학요법으로 인한 백혈구감소증 환자의 침 치료 증례 보고

최진용,조재현,배고은,심소현,서희정,최준용,권정남,이인,홍진우,윤영주,박성하,김소연,한창우,Choi, Jin-yong,Cho, Jae-hyun,Bae, Go-eun,Shim, So-hyun,Seo, Hee-jeong,Choi, Jun-yong,Kwon, Jung-nam,Lee, In,Hong, Jin-woo,Yun, Young-ju,Park, Seong-h 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.5

Leukopenia is a commonly encountered adverse event experienced by cancer patients. It can cause serious infections and delays in chemotherapy. We describe a case of leukopenia induced by colon cancer chemotherapy. After acupuncture treatment, the patient showed improvement in the leukopenia and completed the scheduled chemotherapy without delay or additional administration of granulocyte colony-stimulating factor (G-CSF). Therefore, acupuncture may have a substantial benefit for treatment of leukopenia in this patient.

Heavy Mineral Sands on the Southeastern Continental Shelf of Korea

최진용,박용안,최강원,CHOI, JIN YONG,PARK, YONG AHN,CHOI, KANG WON The Korean Society of Oceanography 1995 韓國海洋學會誌 Vol.30 No.4

A study of heavy mineral sands in terms of heavy mineral group and concentration has been carried out by analyzing 88 grab samples from the continental shelf off the southeast coast of Korea. Heavy mineral groups seem to be outlined and classified into four regions in the study area: 1) the western region; high concentrations of stable minerals, such as opaque mineral, magnetite, garnet and ZTR, 2) Korean Trough region; moderate concentrations of stable minerals, 3) the eastern region; abundant altered mineral and amphibole with minor of pyroxene concentration, and 4) the northeastern shelf-break region; low concentration of stable minerals with abundant altered minerals. The sedimentologic natures of four major heavy mineral regions (groupings) seem to be influenced by physical, dynamic and hydraulic milieu and also aerial and/or subaqueous weathering processes. It seems to be, further, plausible that shallow marine waves and currents associated with neritic dynamic condition of transgressive sea might be very effective on the concentration and groupings (sorting) of heavy min-erals in the surficial sediments of the continental shelf. The pyroxene-abundant heavy mineral suite (group), in fact, seems to suggest a sediment source from Japanese Islands.

임상실습 학생을 대상으로 한 위전도검사와 Nepean Dyspepsia Index(NDI) 설문검사와의 연관성 연구

최진용,배고은,심소현,서희정,서형범,최준용,권정남,이인,홍진우,윤영주,박성하,한창우,김소연,Choi, Jin-yong,Bae, Go-eun,Shim, So-hyun,Seo, Hee-jeong,Seo, Hyung-bum,Choi, Jun-yong,Kwon, Jung-nam,Lee, In,Hong, Jin-woo,Yun, Young-ju,Park, Seong- 대한한방내과학회 2018 大韓韓方內科學會誌 Vol.39 No.4

Objective: The aim of this study was to find a correlation between the Nepean Dyspepsia Index (NDI) and electrogastrography (EGG) in clinical practice students. Methods: In total, 28 students were enrolled. NDI and EGG were measured in all students. NDI was classified as abnormal when the score was 11 or more. In EGG, standard 1 was classified as abnormal if the preprandial or postprandial percentage of normal gastric slow waves of Ch3 was less than 70% or if power ratio of Ch3 was less than 1. Standard 2 was classified as abnormal if standard 1 was met or if the percentage of normal gastric slow waves of Ch3 decreased after meals. Results: NDI and EGG had no statistically meaningful correlation when standard 1 was used, but NDI and EGG had statistically meaningful correlation when standard 2 was used. Conclusions: These findings suggest that NDI and EGG are correlated and that EGG can be used to evaluate the degree of dyspepsia.

홍수 차단

최진용,Choi Jin-yong 한국관개배수위원회 1997 한국관개배수논문집 Vol.4 No.2

인터넷과 웹기반지리정보시스템을 이용한 의사결정지원시스템(I)

최진용,Choi Jin Yong 한국관개배수위원회 2005 한국관개배수논문집 Vol.12 No.1

하계동안 한국 서해 태안반도 연근해에서 부유퇴적물의 운반양상

최진용,박용안,Choi, Jin-Yung,Park, Yong-Ahn 한국해양학회 1998 바다 Vol.3 No.1

1996년 하계동안 한국 서해 대안반도 연근해에서 부유퇴적물의 총함량과 분포경향 및 부유물질의 입도특성을 측정하였고, 수온과 염분의 수괴특성치와 비교하여 부유퇴적물의 운반양상을 해석하였다. 연구해역의 하계 수괴 특성은 수온과 염분이 수직적으로 균질한 연안수괴와 수온약층이 뚜렷한 외양수괴로 구분되는 바, 연안수와 외양수는 강한 조석전선의 영향으로 활발하게 혼합되지 않았다. 그런데 경기만으로부터 유래된 저염의 연안수는 조석전선의 외양역에서 밀도약층대를 따라 중층 저염수를 형성하였고, 남쪽방향으로 이동하는 것으로 분석되었다. 부유물 총함량(TSM)은 경기만 입구의 연안수역에서 5 mg/l 이상으로 높았으며, 외양수역에서 대체로 2 mg/l 이하로 낮게 측정되었다. 외양수역에서는 수괴 홍탁도가 상층과 하층에 비하여 높게 나타나는 중층 혼탁수가 형성되었으며, 경기만 연안해역에서 유래한 부유물질은 위에서 설명된 수괴이동을 따라 남쪽방향으로 이동되는 것으로 규명된다. 부유물질의 입자크기는 전체적으로 2~9 ${\mu}m$의 평균입자 범위이며, 평균입자가 7 ${\mu}m$ 이상인 조립질 부유물은 경기만 연안수역의 혼탁수와 외양역 중층 저염수의 혼탁수에서 우세하다. 따라서 수괴분포와 연관된 부유물질의 입자특성은 부유물질의 이동과 거동방향의 해석에 긍정적인 자료로 여겨진다. The transport of suspended matter was interpreted in the coastal zone off Taean Peninsula during the summer (June) in 1996. Coastal waters were homogenous in water temperature and salinity, whereas offshore waters were characterzed by the strong thermocline. Mixing between coastal and offshore waters are negligeable, largely lessened, due to the existence of strong tidal front between the two water masses. In the offshore area, less saline coastal waters from the Kyunggi Bay are considered to be transported southward along the mid-depth layer of thermocline. Concentration of suspended matters was higher than 5 mg/l in the northern coastal area near the Kyunggi Bay, but generally less than 2 mg/l in the offshore area. Less saline waters along the mid-depth layer in the offshore area sustain maximum turbidities throughout the water column. Therefore suspended matters supplied from the coastal area of Kyunggi Bay are considered to be transported southward by the advective movement of less saline coastal waters. Mean particle size of the suspended matters shows 2~9 ${\mu}m$. Coarse grains (mean size larger than 7 ${\mu}m$) are predominant in the less saline coastal waters extending to the offshore mid-depth waters. Such size distributions of suspended matters together with the characteristics of water masses are considered to be an indicator for the southward movement of suspended matters derived from Kyunggi Bay.

Hydrological Impect Evaluation Web-Based DSS for Local Community

최진용,Choi, Jin-Yong,Engel Bernard A. Korean Society of Rural Planning 2002 농촌계획 Vol.8 No.2

의사결장지원시스템은 다양한 분야에 적용되어 왔으며, 그 중 수자원 및 수질 관련 분야에도 다각적으로 적용되어 왔다. 본 연구에서는 미 농무성의 자연자원보전국(NRCS, Natural Resources Conservation Service)에서 개발한 유출곡선법(Curve Number Method)과 EMC(Event Mean Concentration)을 사용한 L-THIA(Long-Term Hydrologic Impact Assessment) 수문/수질 모형을 강우자료 데이터베이스, 웹기반 지리정보시스템, 웹 사용자 편의 시스템과 통합한 수문/수질 L-THIA web 의사결정지원시스템을 개발하였다. L-THIA web은 도시계획가나 지방자치단체, 또는 지방의 공동체가 사용할 수 있도록 쉽고 단순한 사용자 편의 시스템을 제공하고 있으며, 미국의 50개 본토의 주와 카운티(County) 이름으로 기상자료와 수문토양분류(Hydrologic Soil Group)을 인터넷 지리정보시스템을 이용하여 제공하고 있다. 본 연구는 지방자치단체 및 지역공동체의 실무자를 사용자로 수문/수질 평가 및 관리를 위한 시스템으로 유용하게 활용될 수 있을 것으로 사료된다.

한반도 동해 남부 대륙붕에 분포하는 탄산질-쇄설성분 혼합 퇴적물에 대한 연구

최진용,Choi, Jin-Yong 한국지구과학회 1997 한국지구과학회지 Vol.18 No.6

한반도 동해 남부 대륙붕에 분포하는 탄산질-쇄설성분 혼합 퇴적물에서 성분별 입도분석을 실시하여, 퇴적 환경 및 퇴적기작을 해석하였다. 쇄설성분은 평균입도가 중립사와 세립사 범위였으며, 분급이 양호한 단빈도 입도분포를 나타내었다. 이들 쇄설 퇴적물은 해수면이 낮았던 지난 빙하기동안 해빈 퇴적환경에서 집적되었으며, 전형적인 잔류퇴적물로 해석된다. 패각류가 우세한 탄산질 성분은 거의 파쇄된 상태이며, 표면이 심하게 풍화되었다. 이들 패각도 빙하기동안 천해환경에서 서식하였던 잔류기원 패각편으로 해석된다. 한편 입도특성은 쇄설성 성분에 비하여 다소 조립하며, 분급도는 불량하였다. 이들 패각편 탄산질 성분은 집적된 이후 지속적인 파쇄 및 분급작용에 의해 입도분포의 특징이 조절된 것으로 해석된다. Grain size analysis have been made for the carbonate-detrital mixed sediments on the continental shelf off the southeastern coast of Korea. The detrital components are well-sorted with mean grain size between 2-3 phi. The detrital components are thought to be deposited in the beach environment during the glacial times when the sea level was low, representing typical 'relict' sediments. Most of the carbonate components consist of shell fragments, and are deeply weathered. They are also interpreted as the relict components that were deposited in the shallow marine environment. The carbonate fraction are coarser-grained and poorly sorted compared to the detrital component. The carbonate components are thought to have experienced the continuous environmental control of fragmentation and selective size sorting after the deposition.