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경두개 도플러(TCD)를 이용한 정상군과 뇌경색군의 상호비교연구
최재영,이동원,정승현,이원철,Choi, Jae-Young,Lee, Dong-Won,Jeong, Sung-Hyun,Lee, Won-Chul 대한한방내과학회 1998 大韓韓方內科學會誌 Vol.19 No.1
Background and Purpose : Cerebrovascular reactivity(CVR) can be estimated by measuring the change of cerebral blood flow that occurs during vasostimulation. To estimate the cerebrovascular reactivity, we investigated the change of flow velocity of the middle cerebral artery(MCA) during hyperventilation and hypoventilation with the transcranial doppler. So we studied whether the CVR measured by this method could show a significant difference between the normal and the cerebral infarction subjects and whether the CVR may decrease with age in normal subjects. Methods : Using transcranial doppler, we measured the mean velocity(Vm), the pulsatility index(P.I.) at the resting state, the end of breath-holding and the end of hyperventilation in 36 normal and 10 cerebral infarction subjects, so we calculated the percentile change of mean velocity(%${\Delta}$Vm) and P.I.(%${\Delta}$P.I.) after the vasostimulation. We estimated the change of Vm, P.I., %${\Delta}$Vm and %${\Delta}$P.I. by the age group and compared those parameters between the age-matched normal control and cerebral infarction subjects. Results : The Vm in MCA significantly decreased with age(p<0.05), but there was no significant difference in Vm and P.I. between normal and cerebral infarction subjects. The %${\Delta}$Vm and %${\Delta}$P.I. in response to hyperventilation significantly decreased with age in MCA and there was significant difference in $%{\Delta}Vm$ of MCA after breath-holding between the normal and cerebral infarction subjects. Conclusion : The breath-holding and hyperventilation tests could be non-invasive and useful methods in estimation of the cerebrovascular reactivity and could be applied in the basal and follow-up evaluation of the cerebrovascular reserve of the ischemic stroke patients.
최재영,김성기,민병준,Choi, Jae Yeong,Kim, Sung Ki,Min, Byoung Joon 한국정보처리학회 2013 정보처리학회논문지. 컴퓨터 및 통신시스템 Vol.2 No.9
Current web has evolved to a mashed-up format according to the change of the implementation and usage patterns. Web services and user experiences have improved, however, security threats are also increased as the web contents that are not yet verified combine together. To mitigate the threats incurred as an adverse effect of the web development, we need to check security on the combined web contents. In this paper, we propose a scheduling method to detect malicious web pages not only inside but also outside through extended links for secure operation of a web site. The scheduling method considers several aspects of each page including connection popularity, suspiciousness, and check elapse time to make a decision on the order for security check on numerous web pages connected with links. We verified the effectiveness of the security check complying with the scheduling method that uses the priority given to each page. 최근의 웹은 구현 방법과 이용 패턴이 변화되면서 서로 연결되고 융합되는 형태로 변화하였다. 서비스가 진화되고 사용자 경험이 향상되었으나 다양한 출처의 검증되지 않은 웹자원들이 서로 결합되어 보안 위협이 가중되었다. 이에 웹 확장의 역기능을 억제하고 안전한 웹서비스를 제공하기 위해 확장된 대상에 대한 안전성 진단이 필요하다. 본 논문에서는 웹사이트의 안전한 운영을 위해 안전진단을 외부 링크까지 확장하여, 진단 대상을 선별하고 지속적으로 진단하여 악성페이지를 탐지하고 웹사이트의 안전성을 확보하기 위한 스케줄링 방안을 제안한다. 진단 대상의 접속 인기도, 악성사이트 의심도, 검사 노후도 등의 특징을 추출하고 이를 통해 진단 순서를 도출하여 순서에 따라 웹페이지를 수집하여 진단한다. 실험을 통해 순차적으로 반복 진단하는 것보다 순위에 따라 진단 주기를 조정하는 것이 중요도에 따라 악성페이지 탐지에 효과적임을 확인하였다.
고지방식이로 유도된 C57BL/6 mice에서 감국이 미치는 비만억제 효과
최재영,이자복,김명옥,Choi, Jae Young,Lee, Ja-bok,Kim, Myeong-ok 중소기업융합학회 2021 융합정보논문지 Vol.11 No.4
감국의 유산균 발효를 통한 감국 배양물(CILL)의 비만억제 식품의 소재로서 가능성을 알아보기 위해 고지방식이로 유도된 C57BL/6 mice에서의 체중, body fat mass, T cell 등을 측정하였다. 체중 변화에서 CILL 군 (25.15±2.44 g)은 4주부터 체중 감소를 보였으며, 1주차부터 8주차까지 낮은 증체량을 유지했다(1.00±0.53 g). 8주 체중(30.38±4.17 g)은 HFD 군(60% high fat diet, 34.99±2.09 g) 대비 13.15%의 체중 감소를 보였다. Fat mass는 10.3022±2.8813 g로 감소했으며, 간 절대 중량에서 HFD 군에 비해 감소하였다. CD4+ T cell 4.84±1.33%, CD8+ T cell 7.02±2.26%, CD4+CD8+ T cell 1.46±0.81%로 HFD 군에 비해 높게 측정되었다. 결과적으로 CILL은 비만억제 효과가 있으며, CILL내의 비만억제 물질을 선별한다면 효과적인 비만억제 식품 소재로서의 가능성이 있을 것으로 사료된다. In order to determine the possibility that Chrysanthemum indicum L. cultured with Lactococcus lactis (CILL) is a material for obesity suppression food, the body weight, body fat mass, and T cells were determined in C57BL/6 mice induced by a high fat diet. The CILL (25.15±2.44 g) demonstrated weight loss from week 4 onward and maintained a low weight gain from week 1 to week 8 (1.00±0.53 g). The 8-week body weight (30.38±4.17 g) indicated loss of 13.15% when compared to the HFD (60% high fat diet, 34.99±2.09 g). Fat mass decreased to 10.3022±2.8813 g, and the absolute liver weight decreased relative to that in the HFD. CD4+ T cells were 4.84±1.33%, CD8+ T cells 7.02±2.26%, and CD4+CD8+ T cells 1.46±0.81%, which were all higher than those in the HFD. As a result, CILL can be used as a material for preventing obesity as an effective measure toward reducing weight when consumed orally.
최재영,김성기,이혁준,민병준,Choi, Jae-Yeong,Kim, Sung-Ki,Lee, Hyuk-Jun,Min, Byoung-Joon 한국정보처리학회 2012 정보처리학회논문지 C : 정보통신,정보보안 Vol.19 No.1
Sharing cross-site resources has been adopted by many recent websites in the forms of service-mashup and social network services. In this change, exploitation of the new vulnerabilities increases, which includes inserting malicious codes into the interaction points between clients and services instead of attacking the websites directly. In this paper, we present a system model to identify malicious script codes in the web contents by means of a remote verification while the web contents downloaded from multiple trusted origins are executed in a client's browser space. Our system classifies verification items according to the origin of request based on the information on the service code implementation and stores the verification results into three databases composed of white, gray, and black lists. Through the experimental evaluations, we have confirmed that our system provides clients with increased security by effectively detecting malicious scripts in the mashup web environment. 최근 웹사이트는 매쉬업, 소셜 서비스 등으로 다양한 출처의 리소스를 상호 참조하는 형태로 변화하면서 해킹 시도도 사이트를 직접 공격하기보다 서비스 주체와 연계 서비스, 클라이언트가 상호 작용하는 접점에 악성스크립트를 삽입하는 공격이 증가하고 있다. 본 논문에서는 웹사이트 이용 시 신뢰관계에 있는 여러 출처로부터 다운받은 웹컨텐츠의 HTML 코드와 자바스크립트 코드가 클라이언트 브라우저에서 구동 시 삽입된 악성스크립트를 원격의 검증시스템으로부터 탐지하는 모델을 제안한다. 서비스 주체의 구현코드 정보를 활용하여 요청 출처에 따라 검증 항목을 분류하고 웹컨텐츠의 검증 요소를 추출하여 검증 평가결과를 화이트, 그레이, 블랙 리스트로 데이터베이스에 저장하였다. 실험평가를 통해 제안한 시스템이 악성스크립트를 효율적으로 탐지하여 클라이언트의 보안이 향상됨을 확인하였다.
최재영,Choi, Jaeyoung 디지털산업정보학회 2015 디지털산업정보학회논문지 Vol.11 No.4
Although actual business environment is getting difficult and hard, IT companies tend to shy away from of annual investment. Many firms have already reached the 25 percent level. However, the profit and the result of their annual investment needs to be evaluated objectively. IT investment analysis usually proceeds by comparing benefits and costs of an IT investment. Much of the problem derives from the historical treatment of IT as an overhead expense rather than a capital asset. What is most worrying about the current situation is the pressure to take a very short-term view of IT. Therefore, this research aims to analyses and justify the necessity of Visionary IT Investment. For this, it is crucial to identify the factors, which affect positively Visionary IT Investment and understand the role of CIO and explain the result of Visionary IT Investment, which is differed to related business and by different business environment. As a result of this study, the legitimacy of IT Investment is proved through analyzing the business value of not investing and cost-avoidance strategies.
사상의학적(四象醫學的) 중풍치험(中風治驗) 157례(例)에 대(對)한 임상적(臨床的) 연구(硏究)
최재영,박성식,Choi, Jae-young,Park, Seong-sik 사상체질의학회 1998 사상체질의학회지 Vol.10 No.2
1. 연구배경 및 목적 중풍환자(中風患者)에 대한 임상적 연구를 통하여 중풍치료(中風治療)에 사상의학적(四象醫學的) 관리지침을 설정하고 체질병증(體質病證)의 이해에 도움을 주고자 한다. 2. 방 법 1997년 3월부터 1998년 2월까지 1년간 동국대학교 분당한방병원 체질의학클리닉에 입원치료 받았던 뇌졸중 환자 157명(남자 79명, 여자 78명)을 대상으로 환자의 특성(特性), 병력(病歷), 증상(症狀), 치료경과(治療經過) 등에 관하여 조사하고 분석하였다. 3. 결 과 환자의 체질분포는 태음인(太陰人)이 88명(56.1%), 소양인(少陽人)이 48명(30.6%), 소음인(少陰人)이 21명(13.4%)이었다. 연령의 50세 이상에서 70세 미만이 과반수를 차지하였고 평균은 65세로 나타났다. 뇌졸중의 발병 양태로 뇌경색이 119명(75.8%)으로 대부분을 차지했으며, 뇌출혈이 11명(7.0%), 지주막하출혈이 1명(0.6%), 일과성뇌허혈발작(TIA)이 26명(16.6%)으로 나타났다. 입원시 병증관리지침(病證管理指針)의 상황으로 설태이상(舌苔異常)이 가장 많았고, 수면장애(睡眠障碍), 대사장애(大使障碍), 소변장애(小便障碍) 등의 순서로 나타났으며, 중풍관리지침(中風管理指針)의 호전도(好轉度)를 살펴보면 대사장애(大使障碍)가 87.1%의 호전율(好轉率)로서 가장 높았고, 다음으로 정서장애(情緖障碍), 연하장애(嚥下障碍) 등의 순서였다. 1. Background and Purpose: We intended to make the standards of CVA management of Sasang Constitutional Medicine and be helpful to understand the constitutional symptoms through a clinical study of CVA. 2. Methods: We studied 157 CVA inpatients(79 men and 78 women) who were in constitutional clinic of Dongguk Pundang Oriental Hospital during 1 year from March 1997 to February 1998. We investigated and analysed the characteristics, past histories, symptoms and progresses of patients. 3. Results: The results of constitutional analysis showed 88 Taeumin(56.1%), 48 Soyangin(30.6%) and 21 Soeumin(13.4%). The frequency of strokes was much the same between male and female and the greater part of cases were 50-70 of age. The CVA cases were classified into 119 cerebral infarction(75.8%), 11 cerebral hemorrhage(7.0%), 1 subarachnoid hemorrhage(0.6%) and 26 trasient ischemic attack. From the standards of symptom management, there were abnormality of a coated tongue(63.1%) in most cases, sleeping disorders(48.4%), excremental disorders(44.7%) and urinary disorders(36.9%) on admission. With regard to the rate of improvement in the standards of CVA management, excremental disorders improved 87.1% and emotional disorder 81.0%, swallowing disorder 78.7% and so on.
H<sub>2</sub>S 독성가스감지기가 필요한 정량적 공정설비 기준 및 비상시 안전을 위한 위치선정 방안에 대한 연구
최재영,권정환,Choi, Jae-Young,Kwon, Jung-Hwan 한국가스학회 2018 한국가스학회지 Vol.22 No.2
Design techniques for minimizing the damage caused by leakage of $H_2S$ gas, contained in natural gas and petroleum, have been widely studied abroad in chemical plants that purify and process natural gas and petroleum. However, there is no domestic engineering practice and regulation of $H_2S$. In accordance with the circumstances, this study proposes the quantitative criteria of process equipment to install $H_2S$ toxic gas detector as 500 ppm and explains the valid basis. The $H_2S$ gas dispersion radius up to IDLH 100 ppm is calculated by ALOHA under previous $H_2S$ gas leak accident scenario. The weather conditions of modeling include the conditions of Ulsan, Yeosu and Daesan, the three major petrochemical complexes in Korea. The long radius up to 100 ppm was derived in order of Ulsan, Daesan, Yeosu. For emergency safety the dispersion radius up to 100 ppm of the $H_2S$ gas obtained in this study should be extended to apply the additional $H_2S$ toxic gas detector, and local climate conditions should be considered. 천연가스 및 석유를 정제 및 가공하는 화공플랜트에서 원료에 함유된 황화수소($H_2S$)의 누출로 인한 피해를 최소화시키기 위한 설계 기법들이 세계적으로 널리 연구되어왔다. 그러나 국내에서는 화공플랜트에서 $H_2S$ 가스 피해 최소화를 위한 별도의 뚜렷한 설계 지침 및 규제가 없는 실정이다. 그러므로 본 연구는 $H_2S$ 독성가스감지기를 설치해야 할 공정설비의 $H_2S$ 가스 함량의 정량적 기준을 500 ppm으로 제시하고 타당한 근거를 설명하였다. 또한 ALOHA 프로그램을 사용하여 과거 $H_2S$ 가스 누출 사고를 재구성하여 IDLH 값인 100 ppm까지의 확산 반경을 산출하였다. 모델링의 기상 조건은 국내 3대 석유화학단지가 위치한 울산, 여수, 대산의 조건을 각각 적용하였으며, 울산, 대산, 여수 순서로 긴 반경이 도출되었다. 비상시 안전을 위해서 본 연구에서 얻은 $H_2S$ 가스의 100 ppm까지의 확산 반경을 고려한 추가적인 $H_2S$ 독성가스감지기가 설치되어야 하고, 이때는 반드시 지역별 기후조건이 고려되어야 할 것이다.
질산산화법을 이용한 SiO<sub>2</sub>/Si 구조의 계면결함 제거
최재영,김도연,김우병,Choi, Jaeyoung,Kim, Doyeon,Kim, Woo-Byoung 한국재료학회 2018 한국재료학회지 Vol.28 No.2
5 nm-thick $SiO_2$ layers formed by plasma-enhanced chemical vapor deposition (PECVD) are densified to improve the electrical and interface properties by using nitric acid oxidation of Si (NAOS) method at a low temperature of $121^{\circ}C$. The physical and electrical properties are clearly investigated according to NAOS times and post-metallization annealing (PMA) at $250^{\circ}C$ for 10 min in 5 vol% hydrogen atmosphere. The leakage current density is significantly decreased about three orders of magnitude from $3.110{\times}10^{-5}A/cm^2$ after NAOS 5 hours with PMA treatment, although the $SiO_2$ layers are not changed. These dramatically decreases of leakage current density are resulted from improvement of the interface properties. Concentration of suboxide species ($Si^{1+}$, $Si^{2+}$ and $Si^{3+}$) in $SiO_x$ transition layers as well as the interface state density ($D_{it}$) in $SiO_2/Si$ interface region are critically decreased about 1/3 and one order of magnitude, respectively. The decrease in leakage current density is attributed to improvement of interface properties though chemical method of NAOS with PMA treatment which can perform the oxidation and remove the OH species and dangling bond.
IEC 60079-10-1 edition 2.0에 의한 방폭 설계 한계점 보완 방법에 관한 연구
최재영,변상훈,Choi, Jae-Young,Byeon, Sang-Hoon Korea Safety ManagementScience 2020 대한안전경영과학회지 Vol.22 No.2
IEC 60079-10-1 edition 2.0, the global standard for hazardous area classification, was newly revised in 2015. There are many differences compared to the previous edition 1.0 version, first released in 2008, so it has caused confusion in the industry. In case of edition 1.0, the hazardous area extent can be derived through the mathematical formula, but in case of edition 2.0, there was the problem that the exact hazardous area extent was not known because of the mathematical formula of the plot for applying the hazardous area extent was not presented. In this study, we converted the plot introduced in edition 2.0 to CAD format and derived the plot as the mathematical equations. Through this, we suggest the hazardous area extent formula of three states (heavy gas, diffusive, jet). As the IEC committee did not provide the mathematical formula of the hazardous area extent according to the release characteristic, it is impossible to apply the exact hazardous area extent. In this study, a mathematical approach was derived for the plot introduced in edition 2.0, which can reduce the confusion of the applying hazardous area extent.