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최석렬,김동수,전종휘 인제대학교 1986 仁濟醫學 Vol.7 No.1
장티푸스에 대한 항균요법 실시 30년간에, 국내외에서 발표된 문헌 고찰과 함께 1982년부터 1984년까지 인제의대 부산백병원 내과에 입원한 장티푸스 환자 112예에 대한 임상적 분석을 시도하여 그 얻은 바 성적을 보고한다. The authors have reviewed domestic and foreign literatures related to typhoid fever and a series of 112 inpatients with typhoid fever admitted to Pusan Paik Hospital over a period of 3 years, from January of 1982 to December of 1984. Clinico-epidemiological studies were done comparing with pre- and post-chemotherapeuticera, and the following results were obtained. 1.The seasonal prevalence was predominant in summer. The female-predominance was evident in recent years. 2.Admission date was delayed in chemotherapeutic era. 3.In clinical features, appearance of rose spots, splenomegaly, conscious disturbance, hearing difficulty and epilation were less frequent than pre-chemotherapeutic era. The hepatomegaly was more frequent than the splenomegaly in recent years. 4.Appearance of recurrence, intestinal bleeding and intestinal perforation were more frequent than pre-chemotherapeutic era, and intestinal perforations in childhood have been more experienced considerably than prechemotherapeutic era. Fatality rate is still high comparing to developed country. These trends suggest the unreasonable chemotherapy and inappropriate general care (esp, at home before admission.) 5.Incidence of drug resistant strain is an increasing tendency.