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키토산을 첨가한 콤포짓트 레진의 기계적 성질과 항균성에 관한 연구
최낙찬,모웅남,이용준 조선대학교 구강생물학연구소 2003 口腔生物學硏究 Vol.27 No.1
The purpose of this study was to evaluate the mechanical and anti-microbial properties of newly prepared chitosan G for human gingival fibroblast. Compressive strength, diametral tensile strength and tensile strength of specimens of resin composite, with or without chitosan G incorporated, were measured. Using a SEM (S-4700, Hitach, Japan), pictures of microbes were taken and adherent capability of microbes to the surface of resin composite was investigated. The results were as follows; 1. The values of compressive strength, diametral tensile strength and tensile strength, composite resin containing 7㎎/㎖ chitosan G were higher than the control group(p>0.05) but composite resin containing 40 ㎎/㎖ chitosan G were either the same or lower than the control group(P<0.05) 2. The MIC of newly prepared chitosan G for S mutans KCTC 3065 and C albicans KCTC 7965 were more than 2 ㎎/㎖. 3. The adherent capability of microbes significantly decreased as the amount of chitosan G increased in the test specimens compared to the control group for C aibicans KCTC 7965 (P<0.05) but there was no statistical significance for S mutans KCTC 3065(p>0.05) . 4. The cytotoxicity of newly prepared chitosan G for human gingival fibroblast was not showed. In conclusion, resin composite with chitosan G incorporated did not show any statistically significant difference for mechanical properties (p>0.05) but it showed a significant antimicrobial effect against C albicans (P<0.05).
전자빔 진공증착을 이용한 치과용 임플란트재의 표면 전처리법에 따른 HA 코딩효과
고영무,최한철,최낙찬 大韓齒科器材學會 2002 대한치과재료학회지 Vol.29 No.4
The dental implant materials require good mechanical properties, such as fatigue strength, combined with a high resistance to corrosion. For increasing fatigue resistance and delaying onset of stress corrosion cracking, shot-peening has been used for over 50 years to extend service life of metal components, However, there is no information on the electrochemical behavior of shot-peened and hydroxyapatite(HA) coated Ti-6Al-4V alloys. To increase fatigue strength, good corrosion resistance, and biocompatibility, the electrochemical characteristics of Ti/TiN/HA coated and shot-peened Ti-6Al-4V alloys by EB-PVD have been researched by various electrochemical method in 0.9%NaCl The coated layer and surface showed the formation of dense and uniform surface in the case of TiN/HA and Ti/TiN/HA film coated samples. The hardness of shot-peened Ti-6Al-4V alloys(SPA) increased as SP treatment time increased. Electrochemical measurements showed that, in the case of shot-peened Ti-6Al-4V alloys, the corrosion and pitting potential increased due to the SP induced removal of defects, such as inclusion, scratch, and pore on the surface, whereas passivation and active current density decreased as the SP time increased. For the HA coated samples, pitting and repassivation potential increased in the order of Ti/TiN/Ha > TiN/HA > Ti/HA > HA coated SPA. Results suggest that the best pitting corrosion behavior is shown by Ti/TiN/HA coated SPA with a fatigue strength and biocompatibility.
정준래,홍성욱,한경희,최낙찬,고영무 朝鮮大學校 口腔生物學硏究所 2000 口腔生物學硏究 Vol.24 No.1
The high reactivity of fluoride agents used in topical fluoride treatments have raised important questions on their potential adverse effects on restorative materials. The purpose of this study was to evaluate the effect of various types of fluoride agents used for dental office and home treatments on the color change of some polyacid-modified resin composite(Compoglass and Dyract) and the resin-modified glass ionomer(Fuji Ⅱ LC). Each specimen was treated with 4 kinds of fluoride agents for 4 minutes every day until 8 weeks. The color change was measured using specimens aged up to two months with colorimeter. The resulted were as follows; 1. The color change of resin-modified glass ionomer cement Fuji Ⅱ LC was greater than any other material. 2. The color change of 3 kinds of materials were greatest in contact with 8% SnF_2 solutions. 3. It showed greater color change in case of materials immersed in fluoride agents than in water. In conclusion, Topically applied fluorides induced adverse effects on the color change characteristics of resin-modified glass ionomer cement and polyacid-modified composite resins suggesting that fluoride agents effective in limiting caries should be used with caution with patients who have aesthetic restoratives.