중동호흡기증후군(MERS) 발생관련 전국 약학대학의 실무실습교육 대응현황

최경희,최경숙,이영숙,김재연,정경혜,오정미,최경업,나현오,김은경,Choi, Kyung Hee,Choi, Kyung Suk,Lee, Young Sook,Kim, Jaeyoun,Jeong, Kyeong Hye,Oh, Jung Mi,Choi, Kyung Eob,Ra, Hyeon Oh,Lee, Euni 한국임상약학회 2017 한국임상약학회지 Vol.27 No.1

Background: Pharmacy curriculum change was made from a 4-year program to a 2+4 year program in year 2009 in Korea. The change has resulted in more educational exposures on patient-centered practice environments for about 1,400 hours in the last year of the professional pharmacy program. When the Middle East Respiratory Syndrome (MERS) outbreak hit Seoul and suburban areas and propagated to other provinces in Korea, emergency response to avoid student infection in the pharmacy practice sites became an urgent issue. While other health professional programs such as medicine and nursing had activated emergency preparedness manuals, timely and clear guidelines were not disseminated to all pharmacy programs and protective measures largely relied on individual pharmacy program. Methods: A survey was developed by the Committee on Pharmacy Practice Experience Programs in the Korean College of Clinical Pharmacy to document the status of pharmacy programs during the Korea MERS outbreak in 2015. The 10-question survey was distributed to the pharmacy practice experience coordinators to 34 out of 35 pharmacy schools in Korea by emails. Results: Our findings showed that 82.4% of the program coordinators (28/34) responded to the survey, 96.4% of the programs did not have emergency preparedness manuals, administrative meetings were held in 89.3% of the pharmacy programs, the rotation schedules were modified or withheld in 53.6% of schools, and the changes were mostly observed from the programs classified as MERS outbreak regions. Conclusion: Further needs in establishing the emergency preparedness manual should be explored for pharmacy education stakeholders.

박경리의 『애가』를 통해 본 멜로드라마, 젠더화된 사랑, 그리고 연민

최경희(Choi Kyung-hee) 한국비평문학회 2023 批評文學 Vol.- No.90

박경리의 『애가』(哀歌)』(『민주신보』,1958)는 작가가 본격적으로 장편을 창작하기 위해 자신의 역량을 시험한 첫 작품이자 박경리 문학 세계의 원형을 지닌 소설이다. 그럼에도 『애가』는 몇몇 작품들과 함께 협소하게 연구되어 왔다. 무엇보다 『애가』는 초기 단편에 나타난 사랑과 결혼을 둘러싼 여성 정체성 문제를 밀도있게 그린 소설이다. 뿐만 아니라 60년대 박경리 장편들에서 다양하게 변주된 젠더화된 사랑의 시발점을 보여준 소설이다. 다시 말해 『애가』는 사랑과 결혼이라는 멜로드라마적 소재를 통해 대중성을 확보하면서도 전후 사회의 젠더 인식을 묘파한 60년대 장편들의 특징을 처음으로 구현한 소설이다. 본고는 『애가』가 결혼 장애와 불륜 등의 멜로드라마적 전개를 통해 개인의 사랑과 욕망이 사회 규범과 갈등하는 양상을 이야기하는 가운데 젠더 인식의 시대적 코드를 구현한 점에 주목하였다. 또한 사랑과 결혼을 둘러싼 인물들의 젠더인식에 내재한 인간의 고독과 그에 대한 연민을 살펴 보았다 Aega by Park Kyung-ni is the first work the author tested her capacity to create an earnest full-length novel and is the fiction with an archetypal character of her literary world. Yet, Aega has been studied in a limited manner along with a few other novels. Above all else, Aega is not only a novel that expanded the issue of female identity around love and marriage shown in her early short novels but also one that exhibited the starting point of gendered love variated in different ways in her full-length novels in the 1960s. In other words, Aega secured popular appeal through the romantic material of love and marriage, and simultaneously, embodied the characteristics of full-length novels in the 1960s that openly portrayed the gender perception of postwar society for the first time. This paper focuses on such aspects and analyzed how Aega realized the codes of times of gender perception while discussing the patterns of an individual’s love and desires conflicting with social norms through melodramatic development such as marital barriers and adultery. In other words, it analyzed the gender perception of characters concerning love and marriage. Moreover, the paper reviews the novel as the first full-length novel that materialized human solitude and compassion and solidarity for it, which are the traits of Park Kyung-ni’s literature.

Species Dominance of Tetranychus urticae and Panonychus ulmi (Acari: Tetranychidae) in Apple Orchards in the Southern part of Korea

최경희,이동혁,이순원,윤창만,이선영,도윤수,Choi, Kyung-Hee,Lee, Dong-Hyuk,Lee, Soon-Won,Yoon, Changmann,Lee, Sun-Young,Do, Yun-Su Korean Society of Applied Entomology 2014 한국응용곤충학회지 Vol.53 No.4

이 연구는 사과원에서 20년동안 두 종 응애의 밀도변화를 조사하기 위하여 수행하였다. 사과나무를 가해하는 두 종의 응애 해충, 점박이응애(Tetranychus urticae)와 사과응애(Panonychus ulmi)의 발생을 1992년부터 2011년까지 8개 도시 포함, 한국의 남부지역에 위치한 사과주산지역에서 조사하였다. 20년간의 추세는 많은 과원이 1992년부터 1999년까지는 점박이응애가 주로 가해를 하였지만 2000년도부터는 사과응애가 우점하기 시작했다. 사과응애의 평균관찰밀도는 일정했고 점박이응애의 밀도는 이 기간동안 일정하지 않았다. 5년주기별 발생추세 분석은 점박이응애의 밀도가 2002년 이후에 감소하는 것을 보여주었다. 4월부터 9월까지 월별피해과원율과 두종 응애의 평균발생밀도는 사과응애의 밀도가 4월에 높지만 점박이응애의 밀도가 5월부터 9월까지 높았다. 이런 변화는 살충제 살포횟수, 초경재배관리, 질소비료 사용의 감소와 전체적인 과원관리의 변화 등으로 기인한다. 그러나 이러한 예측은 이를 증명하기 위해 보다 자세한 연구가 필요하다. 본 연구를 통해 비료살표와 같은 재배법과 살충제 살포횟수와 종합적해충관리 등의 환경적 변화가 사과원에서 두종 응애의 우점종과 발생밀도에 영향을 준 것으로 보인다. This study investigated population fluctuations in two mite species in apple orchards over 20-year period. The occurrence of two major mite pests infesting apple trees, two-spotted spider mite Tetranychus urticae and European red mite Panonychus ulmi (Acari: Tetranychidae), was investigated from 1992 to 2011 in major apple-producing districts, including four to eight cities, in the southern part of the Republic of Korea. The 20-year trend revealed that more orchards were infested by T. urticae from 1992 to 1999, but thereafter P. ulmi became dominant. The observed mean density of P. ulmi was consistent, whereas that of T. urticae fluctuated during this period. The analysis of occurrence in four time periods reveals that the density of T. urticae decreased after 2002. The monthly sampling, revealed that the density of P. ulmi was higher in April, whereas the density of T. urticae was higher from May to August. This change may be due to a change in the frequency of pesticide spraying, ground vegetation management, a decrease in nitrogen fertilization, and the overall orchard management practices. However, this projection should be examined in more detail. On the basis of the findings of this study, it can be concluded that cultural practices, including fertilization, and environmental changes, such as pesticide spray frequency and integrated pest management practices, affect species dominance and population densities of the two mite species in apple orchards.

사과 주산지 사과원에서 2종 심식나방류의 발생동향

최경희,이순원,이동혁,김동아,김순경,Choi, Kyung-Hee,Lee, Soon-Won,Lee, Dong-Hyuk,Kim, Dong-A,Kim, Soon-Kyung 한국응용곤충학회 2008 한국응용곤충학회지 Vol.47 No.1

본 조사는 1992년부터 2005년까지 14년간 경남북 및 전북의 $4{\sim}8$개 시군의 사과주산지에서 $16{\sim}30$개 사과원을 대상으로 실시되었으며, 과실을 직접 가해하는 2종 해충인 복숭아심식나방(Carposina sasakii)과 복숭아순나빈 Grapholita molesta)의 발생 및 피해정도를 비교, 분석하였다. 수확기 복숭아순나방에 의한 평균 피해과율은 $0.02{\sim}1.64%$였으며, 1997년을 기점으로 그 이전 연도보다 그 후 연도의 피해가 많은 경향이었다. 반면 복숭아심식나방의 평균 피해과율은 $0.02{\sim}1.30%$였으며, 1998년을 제외하고 피해과율이 0.3% 이하로 극히 낮았다. 복숭아순나방과 복숭아심식나방의 발생과원율은 각각 $13{\sim}71%,\;12{\sim}57%$였으며, 1997년 이후로 복숭아순나방의 발생과원율이 복숭아심식나방 발생과원율에 비하여 지속적으로 높게 나타났다. 각 연도별로 최대 피해를 받은 사과원의 피해과율을 비교해 본 결과 역시 발생과원율의 발생경향과 동일하였으며, 최고 피해 사과원의 복숭아순나방 피해과율은 2005년 20%로 조사연도 중에서 가장 높았다. 복숭아순나방 1세대에 의한 사과나무 신초의 피해율은 $0.1{\sim}8.1%$였으며, 수확기 피해과율 간에는 정의 상관관계를 보였다. 이상의 결과를 종합해 볼 때 최근 관행적으로 관리가 이루어지는 사과원에서 복숭아순나방이 복숭아심식나방에 비하여 우점하는 것으로 판단된다. This survey was conducted from 1992 to 2005 in the major apple producing districts in southern part of South Korea including $4{\sim}8$ cities, to know the occurrence and damage level of two major pests, Carposina sasakii and Grapholita molesta that attack apple fruit. The fruit damage by G. molesta during the harvest period ranged from 0.02 to 1.64%. A tendency of higher damage of G. molesta was observed after 1997 compared with the previous years. The other hand, the fruit damage by C. sasakii was 0.02 to 1.30%, and the damage level was very low with fruit damage of < 0.3% except 1998. The orchard infested with G. molesta was 13 to 71 %, while 12 to 57% with C. sasakii. The rates of orchards where fruit damage by G. molesta was found were higher than those by C. sasakii after 1997. The tendency of fruit damage rates in the orchard where the most fruit damage was found was same with the trend of orchard rates infested with the pests. The maximum damage rate by G. molesta was 20.0% in 2005, while 4.5% by C. sasakii in 1998. The damaged shoot rates by the first generation G. molesta was $0.1{\sim}8.1%$, and it had a positive correlation with the rates of fruit damage during the harvest period. Consequently, it is concluded that G. molesta is dominant species compared with C. sasakii in commercial apple orchards recently.

사과원의 새로운 해충, 복숭아순나방붙이의 발생

최경희,이동혁,변봉규,모찌즈키 푸미아키,Choi, Kyung-Hee,Lee, Dong-Hyuk,Byun, Bong-Kyun,Mochizuki, Fumiaki 한국응용곤충학회 2009 한국응용곤충학회지 Vol.48 No.4

국내 사과원에서 복숭아순나방붙이 발생여부를 조사하기 위하여 성페로몬트랩을 이용하여 조사하였다. 복숭아순나방붙이는 연간 4세대 발생을 보였으며, 월동성충 발생은 5월 상순, 제 1세대는 6월 하순~7월 상순, 2세대는 7월 하순~8월 중순, 3세대는 8월하순~9월이었다. 복숭아순나방붙이의 초기 월동성충 밀도는 높았으나 점차 감소하였다가, 7월 이후 발생밀도가 증가하였다. 성페로몬 조성성분이 비슷한 복숭아순나방과 복숭아순나방붙이 성페로몬트랩에 두 종이 혼재하여 유살되는지를 확인한 결과, 복숭아순나방 성페로몬 트랩에는 복숭아순나방이 98.8% 복숭아순나방붙이가 1.2% 유살되었으며, 복숭아순나방붙이 트랩에는 복숭아순나방붙이가 99.7%, 복숭아순나방이 0.3%로 유살되었다. 심식충류에 의해 피해를 받은 과실에서 유충을 우화하여 동정한 결과, 33.3%가 복숭아순나방붙이였다. 이상의 결과를 종합해 볼 때 복숭아순나방붙이가 사과원의 새로운 주요 과실가해 해충으로 확인되었다. Monitoring was conducted to investigate the occurrence of Grapholita dimorpha Komai in Korean apple orchards using sex pheromone traps. G. dimorpa showed four peaks per year: early May, from late June to early July, from late July to mid August, and from late August to September. After adult emergence of the over-wintered G. dimorpha, G. dimorpha catches was decreased significantly and increased again after July. In G. molesta traps, G. molesta and G. dimorpha were trapped by 98.8 and 1.2%, respectively. Conversely in G. dimorpha traps, G. dimorpha and G. molesta were trapped by 99.7 and 0.3%, respectively. The 30.6% of the moths from the damaged apple fruits were G. dimorpha. This is the first report on G. dimorpha in apple orchards in Korea.

E. coli 발현 시스템에 의해 생산된 recombinant human bone morphogenetic protein-2의 정제와 생물학적 활성

최경희,문금옥,김수홍,윤정호,장경립,조규성,Choi, Kyung-Hee,Moon, Keumok,Kim, Soo-Hong,Yun, Jeong-Ho,Jang, Kyung-Lib,Cho, Kyoo-Sung 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.1

Purpose: Bone morphogenetic protein-2(BMP-2) has been shown to possess significant osteoinducitve potential. There have been attempts to overcome a limitation of mass production, and economical efficiency of BMP. The aim of this study was to produce recombinant human BMP-2(rhBMP-2) from E. coli in a large scale and evaluate its biological activity. Materials and Methods: The E.coli strain BL21(DE3) was used as a host for rhBMP-2 production. Dimerized rhBMP-2 was purified by affinity chromatography using Heparin column. To determine the physicochemical properties of the rhBMP-2 expressed in E. coli, we examined the HPLC profile and performed Western blot analysis. The effect of the purified rhBMP-2 dimer on osteoblast differentiation was examined by alkaline phosphatase (ALP) activity and representing morphological change using C2C12 cell. Results: E. coli was genetically engineered to produce rhBMP-2 in a non-active aggregated form. We have established a method which involves refolding and purifying a folded rhBMP-2 dimer from non-active aggregates. The purified rhBMP-2 homodimer was characterized by SDS-PAGE as molecular weight of about 28kDa and eluted at 34% acetonitrile, 13.27 min(retention time) in the HPLC profile and detected at Western blot. The purified rhBMP-2 dimer stimulated ALP activity and induced the transformation from myogenic differentiation to osteogenic differentiation. Conclusion: rhBMP-2 was produced in E. coli using genetic engineering. The purified rhBMP-2 dimer stimulated ALP activity and induced the osteogenic differentiation of C2C12 cells.

상피하 결합조직 이식술을 이용한 치근피개 술식의 임상적 평가

최경희,백정원,김창성,최성호,조규성,김종관,채중규,Choi, Kyung-Hee,Paik, Jeong-Won,Kim, Chang-Sung,Choi, Seong-Ho,Cho, Kyoo-Sung,Kim, Chong-Kwan,Chai, Jung-Kiu 대한치주과학회 2002 Journal of Periodontal & Implant Science Vol.32 No.3

Exposed root surfaces can cause esthetic problems, hypersensitivity, and root caries. Numerous efforts have been tried to cover the recessed root surfaces, and various techniques have been developed and introduced. Among these, subepithelial connective tissue graft which shows high coverage rate in various researches, has the advantage of good color match, less discomfort to the donor site, rich vascularity, and high predictability. Following results were obtained after investigating 6 and 18 months post operatively, 98 cases of subepithelial connective tissue graft from 48 patients who underwent subepithelial connective tissue graft procedure in the department of periodontology, college of dentistry, Yonsei university. 1. The total average root coverage of Miller class I, II & III were 76.2?24% at 6 months follow-up and 75?25.2% at 18 months follow-up with no statistically significant difference between the follow-up periods.(p<0.05) 2. The percentage of teeth showing complete coverage were 41.9% at 6 months follow-up and 39.2% at 18 months follow-up. 3. At 6 months follow-up, Miller classification I showed 84.9?20.7%, class II showed 82.5?17.7%, and class III showed 62.3?24.5% of coverage. In class III recession, statistically significantly less root coverage was observed compared to class I & II. (p(0.05) 4. At 18 months follow-up, Miller classification I showed 92.2?13.5%, class II showed 84.3?17.4%, and class III showed 59.5?24.5% of coverage. In class III recession, statistically significantly less root coverage was observed compared to class I & II. (p<0.05) In conclusion, subepithelial connective tissue graft for class I and II recession can be used as a clinically predictable treatment modality for root coverage.

최근 경북지역 사과원에서 잎말이나방과 해충 발생동향

최경희,이순원,이동혁,김동아,서상재,권용정,Choi, Kyung-Hee,Lee, Soon-Won,Lee, Dong-Hyuk,Kim, Dong-A,Suh, Sang-Je,Kwon, Young-Jeong 한국응용곤충학회 2004 한국응용곤충학회지 Vol.43 No.3

1998년부터 2000년까지 3년간 경북사과주산지 사과원과 묘목원을 대상으로 잎말이나방류 종을 조사하였으며, 1992년부터 2001년까지 10년간 5-6개 시군의 관행사과원과 폐원에서 잎말이 나방 발생동향과 피해정도를 조사하였다. 사과원에 발생하는 잎말이나방으로는 애모무늬잎말이나방 (Adoxophyes orana), 사과무늬 잎말이나방(Archips breviplicanus), 매실애기 잎말이나방(Rhopobota unipunctana), 사과잎말이나방(Choristoneura longicellana), 복숭아잎말이나방(Acleris fimbriana), 감나무잎말이나방(Ptycholoma lecheana circumclusna), 한국잎말이나방(Archips subrufanus) 등 총 7종이 조사되었다. 이중 애모무늬잎말이나방이 매년 단연 우점종이었으며, 사과무늬잎말이나방과 매실애기잎말이나방은 특정 해에만 1-2 농가에서 다발생하였다. 1980년대 우점종은 사과무늬잎이나방과 매실애기잎말이나방이였으나, 1990년대말 우점종 변화가 이루어진 것으로 조사되었다. 10년간 관행사과원의 잎말이나방 피해정도를 조사한 결과, 평균 피해과율은 $0.67\%$였다. 과실 피해는 3세대 유충에 의해 8-10월에 집중적으로 이루어졌다. This study investigated the species of leafrollers in apple orchards and nursery farms in Gyeongsangbuk-do for three years from 1998 to 2000, and also examined the occurrence and damage of leafrollers in commercial apple orchards in 5-6 cities and districts for 10 years from 1992 to 2001. Total seven species of tortricidae were found in the apple orchards, which were Adoxophyes orana, Archips breviplicanus, Rhopobota unipunctana, Choristoneura longicellana, Acleris fimbriana, Ptycholoma lecheana circumclusna and Archips subrufanus. Among them, A. orana was dominant species every year, and A. breviplicanus and R. unipunctana occurred with a high density in one or two farms in some years. The dominant species in the 1980s were A. breviplicanus and R. unipunctana, but it was considered that dominant species have been changed in the late 1990s. According to the result of leafroller damage in commercial apple orchards for 10 years, the mean fruit damage rate was $0.67\%$. Fruit damage was observed frequently between August and October by third-generation larvae.

1960년대 초기 여성지와 소설에 나타난 국가주의 연구

최경희(Choi, Kyung-Hee) 우리문학회 2018 우리文學硏究 Vol.0 No.57

이 논문은 1960년대 초 근대화 시기 『가정생활』, 『여상』, 『여원』 등과 손창섭의 『부부』에 나타난 사랑과 성, 현대와 전통, 여성과 국민, 가정과 국가 등이 국가주의를 내면화한 것을 포착해 ‘여성의 국민화’라는 젠더 레짐으로 살펴본 논문이다. 여성의 국민화는 근대화 이념과 정책을 여성의 정체성과 일상에 정착시키길 의도한, 근대화의 젠더 레짐을 고착화시킨 국가동원체제이다. 본고는 여성지들이 가정재건과 국가재건이라는 추상적이고 관념적인 근대화 담론을 여성성에 내면화하기 위해 국민이라는 모호한 정체성, 즉 추상적이면서 경계가 불분명한, 그러면서도 근대적 자아를 추동하여 자발적으로 국가동원체제에 협조하도록 하는 데에 매우 효과적인 국민이라는 개념을 잘 활용해 가정과 국가 재건자의 롤모델을 선전․동원한 점을 검토하였다. 또한 본고는 손창섭의 『부부』가 육체적 사랑과 정신적인 사랑이라는 인물들의 사적 감정에 내면화된 개인과 국민, 가정과 국가라는 공적 담론을 분석함으로써 젠더 레짐의 당대적 실체를 구체적으로 묘파한 점을 밝혀 보았다. 『부부』가 개인의 사랑과 성에 내면화된 여성성과 국민성, 가정재건과 국가재건 프레임을 실랄하게 묘파함으로써 보다 근원적인 사랑과 성에 대한 입체적이고 복합적인 질문을 던진 작품임을 살펴보았다. The early 1960s was a period when modernizationprojects started, and private homes were seen as belonging to society and the nation as a whole. Women’smagazines promoted women’s obligations as social norms in the private sphere. While the discourse on love marriages made public the emotions involved in personal matters such as love, marriage, etc., and stressed the importance of emotion in daily life, to a considerable extent, it also emphasized an emotional “education” that imposed norms and rules. Love and marriage were thus seen as aspects of a pure individual life freely chosen by each man and woman involved in such a relationship, but that also remained deeply influenced by society’s rules and the communal environment. The tragic conclusion led to a criticism of the suppressed social rules that did not allow for freelove between individuals, and included an implicit warning that living as a woman as expected by society could mean sacrificing one’s identity as an individual.

경북 사과주산지 사과원의 최근 주요 해충 발생상황

최경희(Kyung-Hee Choi),이순원(Soon-Won Lee),이동혁(Dong-Hyuk Lee),김동아(Dong-A Kim),서상재(Sang-Je Suh) 한국원예학회 2004 한국원예학회 학술발표요지 Vol.2004 No.5