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김학수,김영중,오영하,노영호,안민,박병익,차영학,김윤권,전종구,안현석 대한신장학회 1999 Kidney Research and Clinical Practice Vol.18 No.2
Alport's syndrome is a hereditary disorder whose incidence is 1 in 10,000 in general population, and, majority are developed in childhood, so it is rare to develop in adults. This syndrome consists of hematuria, sensorineural hearing loss, and lenticonus, in classic form. However, there are many atypical forms which have not all clinical manifestations. Although most asymptomatic hematuria in adults results from IgA nephropathy(Berger's disease) or thin basement disease(benign hematuria), Alport's syndrome should be considered as a cause of hematuria. The authors experienced a case of Alport's syndrome in a 21-year-old man who showed only hematuria and proteinuria, and who was diagnosed by history, family history, audiogram, and kidney needle biopsy. So, we report this case with a review of literature.
전투 경찰에서 발생한 렙토스피라병 12 예에 대한 역학 및 임상적 고찰
장원규(Won Gyu Chang),송명준(Myung Jun Song),차영학(Young Hak Cha),김경곤(Kyoung Gon Kim),백운희(Un Hee Paik),김윤권(Yun Kwon Kim),김소연(So Yon Kim),김영중(Young Jung Kim),조민구(Min Koo Cho),이권전(Gwon Jun Lee) 대한내과학회 2001 대한내과학회지 Vol.61 No.5
N/A Background: There were two occurrences of typhoon and the floods in Korea from early to late September, 2000. The Korean Combat Police and policemen participated in cleaning activities at the flooded area. Leptospirosis broke out among these participants . This study describes the epidemiological and clinical characteristics of leptospirosis patients among policemen. Methods: Of 16,750 individuals involved, 3,752 subjected to passive hemagglutination antibody (PHA) test at the Regional Health Care Units or the National Police Hospital. With 1 case of dead plus 12 cases which were turned out to be seropositive by PHA test and confirmed by microagglutination (MA) test, epidemiological and clinical characteristics were studied by questionnaire survey, laboratory test, and history of treatment while being hospitalized. Results: The seropositive rate of leptospira antibody was 0.3% (12/ 3,752). All 12 serpositives were bare-footed while working at the flooded area and of these, 8 patients (67%) were noticed abrasions either on hand or feet. However, no statistically significant correlation was found between the duration of outdoor activity and the seropositive rate (r=-0.46, p =0.36). There were clinical difference among patients who has the same serotype of leptospirosis, physical conditions, circumstance and the same work area. Two abnormal EKG results are present, the one who complained of chest pain is myocardial ischemia and the other who didn`t complain of any symptoms is sinus pause. Correlation between the febrile period before and the duration of fever after the use of antibiotics was estimated as ; febrile period after antibiotics use = 0.102804+0.995327×febrile period before antibiotics use (p =0.058). Conclusion: When leptospirosis is related to group activities, it is possible to educate in advance and to manage systematically afterwards, it may prevent the occurrence of leptospirosis or the related complications.(Korean J Med 61:553-561, 2001)
A형 간염 바이러스 항체 ( anti-HAV IgG ) 발현율에 대한 역학적 조사 ( 전투경찰을 대상으로 )
차주영(Ju Young Cha),전종구(Jong Koo Jun),안민(Min An),오형모(Hyung Mo Oh),김윤권(Yun Kwoen Kim),김소연(So Yon Kim),김영중(Young Jung Kim),차영학(Young Kak Cha),박병익(Byung Yik Park),이권전(Kwoen Jun Lee),조민구(Min Koo Cho) 대한내과학회 1999 대한내과학회지 Vol.57 No.6
N/A Background : Hepaitis A virus(HAV) infection occurs commonly during early childhood. Recent improvements in sanitation and hygiene have resulted in a decrease in HAV infection among children, while the clinical illness of hepatitis A and prevalence of antibody to HAV(anti-HAV IgG) have been increased, particularly in the 3rd decade of young male adults. We studied a seroepidemiology of anti-HAV IgG in combat policemen who were living together during their service in the combat police force. Methods : We measured anti-HAV IgG(HAVAB, Abbott) from 1,009 healthy subjects with no history of transfusion of any blood products during the last 6 months. The mean age was 20.8 years. Results : Overall, anti-HAV IgG was detected in 30.2% of study subjects. According to age, the positive rates of antibody were 15.7%, 25.9%, 31.5%, 38.1%, 43.5%, and 50.0% in 19, 20, 21, 22, 23, and 24 years respectively. The positive rates of anti-HAV IgG as to period of service were 17.3%, 28.1%, 40.9% in 0 month, 1-12 months, 13-24 months respectively. The positive rates of anti-HAV IgG were 27.0% in the urban group, 39.8% in the rural group. Conclusion : The positive rates of anti-HAV IgG in our data low compared with those of previous reports. We think that group living condition such as living in dormitories or barracks can be a risk factors for hepatitis A infection and that improvements to the sanitary system and active immunization would be necessary for prevention of it.(Korean J Med 57:988-993, 1999)