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Amplitude Fluctuation in Intracavity Second-Harmonic Generation
池聖吉 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.2
본 논문에서는 내부 공진기 구조를 이용하는 제2고조파 발생에서 일어나는 출력 변동의 수치해석을 통하여 그 발생 원인을 분석하였다. 그 주된 원인으로는 homogeneously broadened 이득을 레이져 물질로 사용하였을 때 두 개의 모드 사이의 이득 교차 포화와 비선형 단결정 내에서의 비선형 커플링인 것을 알 수 있었다. homogeneously broadened 레이저의 경우 단일 모드가 자연적으로 발진하지만, 온도 변화에 민감하게 변하는 비선형 단결정의 복굴절율과 부르스터 편광기의 복합적인 효과로써 모드 선택이 일어나고 경우에 따라서 어떠한 모드도 부르스터 편광기를 광손실 없이 통과 할 수 있는 위상 차이를 형성하지 못하면, 두 개 이상의 모드가 동일한 광손실을 취하게 됨으로 동시 혹은 반복적으로 발진 할 수 있다.
池聖吉 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-
We demonstrated an efficient vacuum packaging process of glass panel. The time required for the completion of the entire process is considerably shortened through the use of a high power, continuous-wave infrared laser. In our panel packaging scheme, the most vital part of the panel is kept at temperature below 300 C. The final pressure in the panel hermetically sealed and exhausted via non-evaporable getter activation was 2 x 10^(-6) ton.
수종 한약제의 위암세포에 대한 항암작용 효능검색 및 약리작용에 관한 분자생물학적 연구
유진화,류봉하,이지향,김진성,박재훈,지성길 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 1999 東西醫學硏究所 論文集 Vol.1999 No.-
Traditional oriental medicines have been used for treatment of various kinds of human cancers for long times and some of them proven to be effective clinically. However. the pharmacological actions and mechanisms related to cancer treatment are generally unknown. In an effort to clarify the action mechanisms of several oriental medicines used for cancer treatments, we planned this experimental procedures. We selected Cordyceps sinensis (冬蟲夏草). Punellae Herba (夏枯草), Rehmanniae Radix (熟地黃), Paeoniae Radix (白芍約), Oldenlandiae Herba (白花蛇舌草), Portulacae Herba (馬齒?), Scolopendra subspinipes mutilans (蜈蚣), Mylabris Phalerata (斑?), Phellinus igniarius(桑黃), Ganodermae Lignum(靈芝) for evaluation, which have been used for patients of gastric cancers. The twenty grams of medicines were boiled in 100㎖ of water for 1 hour and filtered with 0.2 ㎛ pore-sized filter unit to remove insoluble particles. Initially we evaluated the effects oriental medicines on growth inhibition in stomach cancer cells. The gastric cancer cell line, AGS, was cultured in RPMI 1640 supplemented with 10% heat-inactivated fetal bovine serum and treated with 10% oriental medicines per 1 ㎖ of medium up to 48 hours. The specimens were subjected to MTT assay for evaluation of growth inhibition. We found that Mylabris phalerata (斑? ) markedly suppressed the growth of cancer cells as shown in results. Next, we checked the effects of oriental medicines on cancer on cell cycles and apoptosis. Mylabris phalerata (斑? ) inhibited cell cycle progression of cancer cells as compared with control cells and cells treated with other medicines. In addition, Mylabris phalerata (斑? ) induced apoptosis in 30-40% of stomach cancer cells within 24 hours. Other oriental medicines used for this experiments did not show apoptosis-inducing effects on cancer cells. Finally, we determined the expression levels of genes associated with cell cycle and apoptosis. The expressions of Bcl-2 and bcl-XL were downregulated by the treatments of Mylabris phalerata (斑? ), However, the expression levels of genes related to cell cycles were not altered significantly. In conclusion, we found that Mylabris phalerata(斑? ) has in vitro growth-inhibiting and apoptosisinducing effectd on stomach cancer cells. However, we think that at least animal experiments are necessary for evaluations.