측두엽 간질에서 일측성과 양측성 포도당 대사저하 군의 임상양상의 차이

주은연,홍승봉 대한간질학회 2004 대한간질학회지 Vol.8 No.1

노인의 우울감소에 미치는 원예치료의 효과와 소재 색상 선호도 조사

주은연,김홍열 인간식물환경학회 2008 인간식물환경학회지 Vol.11 No.1

This study set out to research preference of material color, to analyze the impacts changes of the depression an more effective of Horticultural therapy program for the old adults. The subjects were made out of the old adults who were taken care at 'Daeduk Senior Welfare Service Center' located in Namgu, Daegu Metropolitan City. The experiment was conducted once a week form Aug. 9 to Nov. 1, 2005, total in 13 times. To estimate the research subject's remedial value, GDS-K(Geriatric Depression Scale in Korean) was implemented before and after performing a horticultural therapy program, and each time a color preference for program key materials was examined. The evaluation is as follows : GDS-K evaluation indicated that the average point for entire research subjects prior to its implementation presented 23.4, while it was 16.6 with 7 drop after its implementation, which consequently implied a gradual decrease in melancholy and statistically showed a significant different(P<.05). Findings on the survey regarding a color preference for key materials revealed that cut flower, artificial flower, and colored stone, and moss preferred red color the most, while seed liked green color the most and floral form cared for pink the most. The findings drawn so far indicated that the horticultural therapy using bright and clear colors provided a positive impact for old people's melancholy. I conclude that it would be helpful for changing one's mood and improving an melancholy, to let horticultural therapy programs use their materials mainly with bright and clear colors, so as to make deeply-melancholy old people feel refreshed.

Gray Matter Concentration Abnormality in Brains of Narcolepsy Patients

주은연,김성태,홍승봉,태우석 대한영상의학회 2009 Korean Journal of Radiology Vol.10 No.6

Objective: To investigate gray matter concentration changes in the brains of narcoleptic patients. Materials and Methods: Twenty-nine narcoleptic patient with cataplexy and 29 age and sex-matched normal subjects (mean age, 31 years old) underwent volumetric MRIs. The MRIs were spatially normalized to a standard T1 template and subdivided into gray matter, white matter, and cerebrospinal fluid (CSF). These segmented images were then smoothed using a 12-mm full width at half maximum (FWHM) isotropic Gaussian kernel. An optimized voxel-based morphometry protocol was used to analyze brain tissue concentrations using SPM2 (statistical parametric mapping). A one-way analysis of variance was applied to the concentration analysis of gray matter images. Results: Narcoleptics with cataplexy showed reduced gray matter concentration in bilateral thalami, left gyrus rectus, bilateral frontopolar gyri, bilateral short insular gyri, bilateral superior frontal gyri, and right superior temporal and left inferior temporal gyri compared to normal subjects (uncorrected p < 0.001). Furthermore, small volume correction revealed gray matter concentration reduction in bilateral nuclei accumbens, hypothalami, and thalami (false discovery rate corrected p < 0.05). Conclusion: Gray matter concentration reductions were observed in brain regions related to excessive daytime sleepiness, cognition, attention, and memory in narcoleptics with cataplexy.

만성 뇌폐흡충증 환자에서 발생한 단순간질중첩증 : 발작기-발작간기 스펙트 감산을 이용한 간질발작의 국소화

주은연,김지현,김형진,신희영,태우석,정기영,서대원,김승환,홍승봉 대한간질학회 2004 대한간질학회지 Vol.8 No.1

지속적 양압기의 실제 임상 사용

주은연 대한수면연구학회 2008 Journal of sleep medicine Vol.5 No.2

Positive airway pressure (PAP) is the treatment of choice for patients with moderate-to-severe obstructive sleep apnea (OSA). PAP can effectively reduce the apnea-hypopnea index and improve subjective and objective sleepiness. Also it can gives benefits in sleep quality and quality of life for both the patient and bed partner. Since continuous PAP (CPAP) treatment of OSA was described, additional modes of pressure delivery have been developed (bilevel PAP, autoadjusting PAP, flexible PAP). While none of the variants of PAP improves adherence in unselected patients compared to CPAP, individual patients may respond to a change in pressure mode. Although attended PAP titration remains the standard of practice for selecting a treatment pressure, use of autotitrating PAP devices in the unattended setting can provide an effective titration alternative with careful patient selection and review of titration results. However, despite the increase in PAP treatment options, lack of acceptance and inadequate adherence to PAP therapy remain the major causes of treatment failure. Heated humidification can improve PAP adherence, especially in patients with nasal congestion or dryness.

경로당 여가활동을 위한 원예활동 선호도 조사

주은연,김홍열,윤선태 인간식물환경학회 2006 인간식물환경학회지 Vol.9 No.4

Adverse Effects of 24 Hours of Sleep Deprivation on Cognition and Stress Hormones

주은연,Cindy W Yoon,구대림,김대영,홍승봉 대한신경과학회 2012 Journal of Clinical Neurology Vol.8 No.2

Background and Purpose The present study was designed to investigate whether 24 h of SD negatively affects the attention and working memory and increases the serum concentrations of stress hormones, glucose, and inflammatory markers. Methods The acute effects of sleep deprivation (SD) on cognition and the stress hormones were evaluated in six healthy volunteers (all men, age 23-27 years). All were good sleepers, had no history of medical or neuropsychiatric diseases, and were not taking any kind of medication. All of the volunteers were subjected to the Continuous Performance Test (CPT) for attention and working memory of cognition and blood tests both before and after 24 h of SD. Electroencephalographic monitoring was performed during the study to confirm the wakefulness of the subjects. Results SD significantly elevated the serum concentrations of stress hormones (cortisol, epinephrine, and norepinephrine), but serum levels of glucose and inflammatory markers were not changed compared to baseline. For easier steps of the CPT the subjects performed well in giving correct responses after SD; the correct response scores decreased only at the most difficult step of the CPT. However, the subjects performed consistently poor for the error responses at all steps after SD. There was no correlation between the CPT scores and stress hormone levels. Conclusions The 24 h of SD significantly heightened the levels of stress hormones and lowered attention and working memory. The acute SD condition seems to render the subject more susceptible to making errors.

원예치료가 시설보호아동의 정서발달 및 대인관계에 미치는 영향

주은연,김홍열 인간식물환경학회 2008 인간식물환경학회지 Vol.11 No.1

The purpose of this study is to examine effect of horticultural therapy on mental development and interpersonal relationship of institutionalized children. This study executed horticultural therapy program of the total 16 times by one time a week to institutionalized children who have used H-Institution for children in Kyungsang Buk-do from September 21, 2006 to January 4, 2007. To examine effect of horticultural therapy, this study used the korean personality rating scale for children(KPRC), withdrawn scale, self-concept scale, and interpersonal relationship scale, and investigated before and after executing the program for comparison.Mental development was reduced from 90.87 before executing to 72.25 after executing horticultural therapy, and it was statistically significant(P<0.01). Also in withdrawn scale test, the mean point was appeared to be significantly raised(P<0.05) from 8.875 before executing to 6.25 after executing the program, and horticultural therapy was considered to be effective to mental stability of institutionalized children. In result of evaluating self-concept, it was raised from 207.37 before executing to 228.5 after executing, and it showed the significant difference(P<0.01). Also in result of evaluating interpersonal relationship, it was raised from 73.25 before executing to 83.75 after executing, and it showed the significant difference(P<0.05). Accordingly, horticultural therapy is considered to be effective to mental development and interpersonal relationship of institutionalized children.

뇌파의 연령별 스펙트럼 및 비선형적 분석

주은연,김응수,박기덕,최경규 대한임상신경생리학회 2001 Annals of Clinical Neurophysiology Vol.3 No.1

Background & Objectives : Fractal Dimension(FD) could be an index of correlation between variable parameters in non-linear chaotic signals. We tried to demonstrate that EEG wave is compatible with chaotic waves by measuring the Lyapunov exponent index and compared the difference of FD between variable age groups(teens, 30's, 50's) Methods : We estimated the Lyapunov exponent index and the FD from digital EEG data among five persons in each normal age groups by using the software which is programmed in our laboratory. Statistical analysis was done with SPSS win 8.0. The statistical differences of Lyapunov exponent index and FD between each electrodes and each age groups were done with ANOVA and paired sample t-test. Result : The Lyapunov exponent indexes were larger than 1 in each electrode and age groups. Except in 30 th age group. In this group the FD of right hemisphere is larger than that of left hemisphere. Conclusion : The result of Lyapunov exponent index means EEG wave is a non-linear chaotic signal. And the results of FD suggest that chaotic parameters of right hemisphere is larger than those of left hemisphere at rest at least in younger people. We think that chaotic parameters can be a useful tool in investigating the variable diseases or brain states.

원예치료가 시설보호아동의 자아개념 및 인성발달에 미치는 영향

주은연,김홍열 인간식물환경학회 2006 인간식물환경학회지 Vol.9 No.4