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消癌散의 경구투여에 의한 마우스 B16 흑색종 세포의 폐전이에 대한 항전이 효과
주성민,양휘훈,우원홍,정우열,조원준,이기영,전병훈,김원신 대한동의생리학회,대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.6
We have examined the inhibitory effect of oral administration of Soamsan, a Korean traditional medicine, on lung metastasis by inoculation of mouse B16 melanoma cells into the tail vein. Oral administration of Soamsan for 20 days after tumor inoculation resulted in dose-dependent inhibition of lung metastasis. Soamsan at the dose of 40 mg/day/mouse for 20 days significantly inhibited the metastasis. Treatment with Soamsan (40 mg/days/mouse) for 7 days before and after tumor inoculation result in significant inhibition of lung metastasis. On the other hand, in the case of treatment with Soamsan for 7 days after 7 days from tumor inoculation, the inhibitory effect was not detected. Soamsan significantly inhibited the lung metastasis of B16 melanoma cells in mice pretreated with anti-mouse NK 1.1 monoclonal antibody and untreated nomal mice, whereas it did not inhibit efficiently metastasis in 2-chloroadenosine-pretreated mice. Also, Soamsan enhanced the antigen specific immune response by stimulating the activation of B lymphocytes (Kim et al., 2001). These results suggest that oral administration of Soamsan inhibited lung metastasis of B16 melanoma cells, possibly through a mechanism mediated by the activation of marcrophages and B lymphocytes in the host immune system.
주성민,방희선,방한서,박광수 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.1
The effect of trailing heat sinks on welding-induced deformation and residual stress was numerically simulated using the finite element analysis (FEA) in this study. A 3-D thermal elastic plastic finite element model using a 2 mm-thick 304 stainless steel sheet was developed to simulate heat sink welding. In the numerical simulations, the parameters of the heat sink welding, such as the distance between the welding heat source and the heat sink, and the size of the heat sink are varied to compare the variation of out-of-plane displacement and residual stress. This numerical simulation indicated that compared to conventional welding, trailing heat sink welding showed, first, smaller deformation and residual stress, second, a significantly reduced out-of-plane displacement under optimal heat sink welding conditions, and third, a reduced overall residual stress developed although no significant differences were seen in the maximum values of welding residual stress.
Local compression에 의한 CTOD 시편내의 용접잔류응력 재분포
주성민,윤병현,장웅성,방한서,방희선,노찬승,Joo, Sung-Min,Yoon, Byung-Hyun,Chang, Woong-Seong,Bang, Han-Sur,Bang, Hee-Seon,Ro, Chan-Seung 대한용접접합학회 2009 대한용접·접합학회지 Vol.27 No.6
When conducting CTOD test, especially in thick welded steel plate, fatigue pre-cracking occasionally failed to satisfy the requirements of standards thus making the test result invalid. Internally accumulated residual stress of test piece has been thought as one of the main reasons. The propagation of fatigue crack, started from the tip of machined notch, which might have propagated irregularly due to residual stress field. To overcome this kind of difficulty three methods to modify the residual stress are suggested in standard i.e. local compression, reverse bending and stepwise high-R ratio method. In this paper not only multi pass welding but also local pre-compressing process of thick steel plate has been simulated using finite element method for clarifying variation of internal welding residual stress. The simulated results show that welding residual stress is compressive in the middle section of the model and it is predominantly increased after machining the specimen. Comparing as-welded state all component of the welding residual stress changing to compressive in the tip of machine notch whereas residual stress of the outer area remain as tensile condition relatively. Analysis results also show that this irregular residual stress distribution is improved to be more uniformly by applying local compression.
음악전공자의 진로문제에 관한 국내 연구동향 분석: 2000년~2022년
주성민,이제경 한국문화교육학회 2023 문화예술교육연구 Vol.18 No.6
The purpose of this study was to present the tasks of career education through domestic research trends on career problems of music majors. For this purpose, 52 research papers(31 journal articles, 21 thesis/dissertation papers) published between 2000 and 2022 were analyzed according to basic information, research subject, research method, and research topic. The results were as follows: First, research has increased rapidly when the university restructuring policy was implemented since 2011. Second, research was mainly conducted by researchers in the fields of musicology and music education. Third, most of studies were conducted including Western classical music majors and undergraduates at the college of music as the main subjects. Forth, although quantitative research methods were used the most, the proportion of mixed research methods was relatively higher compared to studies conducted on general university students, and qualitative research methods were on the rise. Fifth, research topic was divided into problems of curriculum and factors affecting career decision-making. Based on these results, the tasks of career education were discussed.
RF Magnetron sputtering을 이용한 ${Ce_{1-x}}{RE_x}{O_{2-y}}$ 박막성장
주성민,김철진,박병규 한국세라믹학회 2000 한국세라믹학회지 Vol.37 No.10
RF 마크네트론 스퍼터법으로 Ce의 일부를 희토류 원소로 치환한 Ce$_{1-x}$RE$_{x}$O$_{2-y}$(0.1$\leq$x$\leq$0.4, RE=Y, Nd) 박막을 Si(111), $Al_2$O$_3$(1012) 기판 위에 1450~1$600^{\circ}C$로 소결한 target을 이용하여 성장시켰다. Ce$_{1-x}$RE$_{x}$O$_{2-y}$ 박막의 성장시 기판온도 및 증착시간 등을 변화시켜 성장시켰으며, 성장된 박막의 특성분석은 XRD, SEM, TEM으로 행하였다. 증착된 박막의 방향성 및 결정성장 거동은 증착온도 및 시간에 따라 차이를 보였다. Si(111) 기판 위에 증착된 Ce$_{1-x}$Y$_{x}$O$_{2-y}$(x=0.3) 박막의 경우, 80$0^{\circ}C$에 비해 7$50^{\circ}C$에서 증착 시간에 따른 (111) 우선배향성의 정도가 나은 결과를 보였으며, $Al_2$O$_3$(1012) 기판 위에 증착한 Ce$_{1-x}$Nd$_{x}$O$_{2-y}$(x=0.3) 박막 또는 (111) 우선배향성을 나타내었다.을 나타내었다.
자체연소반응법에 의한 $B_4C$ 분말합성(자체연소반응법에 의한 $B_2O_3$로부터 $B4_C$ 방탄소재개발)
주성민,김형순,원창환,Ju, Seong-Min,Kim, Hyeong-Sun,Won, Chang-Hwan 한국재료학회 1996 한국재료학회지 Vol.6 No.3
자체연소반응법에 의하여 탄화붕소(B4C)를 합성함에 있어서 자체적으로는 반응이 이루어지지 않아서 간접점화법인 화학로법(Chemical Furnace)으로 합성을 하였으며, 성형압력과 몰비를 변수로 하여 연소온도 및 연소속도의 변화를 측정하였다. 성형밀도가 이론밀도의 70%에서 연소온도와 연소속도가 가장 높았으며, 몰비에 대한 영향은 표준비였을 때 연소온도와 연소속도가 가장 높았다. 그리고 성형밀도에 따른 입자의 크기변화는 성형밀도가 높을수록 입자의 크기는 작아졌으며 따라서 비표면적은 커졌다.