젊은 여성들에서 고강도 운동 후 혈중 산화스트레스 지표들의 변화

주미현 대한임상건강증진학회 2008 Korean Journal of Health Promotion Vol.8 No.3

Background It is reported that high-intensity physical exercise may induce oxidative stress. Therefore, the purpose of this study was to investigate the change of blood oxidative stress markers after a high-intensity exercise in young women Methods Eight sedentary women who have regular menstrual cycles participated in this study. Regular menstrual cycles were determined by basal body temperature (BBT) and urinary ovulation test for 2 mouths prior to this study. All subjects performed the bicycle ergometer exercise (for 22.5 min at 80% VO2max). Lactate was determined from blood of Pre-and Post-exercise (PO). Blood oxidative stress markers (erythrocyte thiobarbituric acid reactive substances: TBARS, Superoxide dismutase: SOD, Glutathione Peroxidase: GPx and serum Creatine PhosphoKinase: CPK) were determined from blood of Pre- and Post-exercise (PO, P2, P12 and P24). Results In this results, lactate was increased clearly at the P0 compared with Pre (p<0.05). And TBARS increased significantly P12 compared with Pre (p<0.05). SOD activity also decreased significantly P24 compared with Pre (p<0.05). However, GPx activity did not show statistically significant changes by the high-intensity exercise. CPK significantly decreased P0 and increased significantly P12 compared with Pre (p<0.05). Conclusions In the menses, high-intensity exercise may increase the blood oxidative stress in the young woman which has a normal menstrual cycle. In particular, the influence of ROS is very high after P12. Therefore, sedentary women had better do not intense exercise in the menses. 연구배경 적절한 강도를 벗어난 급격한 운동은 산화스트레스를 유발할 가능성이 높은 것으로 보고되고 있다. 따라서, 본 연구는 젊은 여성들에서 고강도운동 후 혈중 산화스트레스 지표들의 변화에 대하여 조사하는데 목적을 두었다. 방 법 운동 습관이 없고, 규칙적인 월경주기를 지닌 8명의 일반여성들이 본 연구에 참가하였다. 2개월간의 기초체온 측정과 뇨에 의한 배란 검사를 실시하여, 규칙적인 월경주기를 지닌 것으로 확인되었다. 모든 피험자는 고강도운동(80% VO2max 강도, 22.5minute)을 실시하였다. 젖산은 운동 전(Pre)과 운동 직후(PO)에 채혈된 혈액에서 측정되었다. 혈중 산화스트레스 지표 (적 혈구 TBARS, SOD, GPx 그리고 혈청 CPK)들은 Pre, PO, P2, P12 및 P24에서 채혈된 혈액에서 측정되었다. 결 과 혈중 젖산은 Pre와 비교하여 P0에서 유의하게 증가하였다. 적혈구 TBARS는 Pre와 비교하여 P12에서 유의하게 증가하였다. 적혈구 SOD 활성은 Pre와 비교하여 P24에서 유의하게 감소하였다. 적혈구 GPx활성은 Pre와 비교하여 운동 후 시간경과에 따른 유의한 변화를 나타내지 않았다. 혈청 CPK는 Pre와 비교하여 P0에서는 유의하게 감소하였으며, P12에서는 유의하게 증 가하였다. 결 론 규칙적인 월경주기를 지닌 일반여성에서 월경기에 실시한 고강도운동은 혈중 산화스트레스를 증가시키며, 특히 고강도 운동을 마친 뒤 12시간 이후에는 활성산소의 영향이 가장 큰 것으로 나타났다. 그러므로 운동습관이 없는 일반여성은 월경기에 강도가 높은 격렬한 운동을 피하는 것이 바람직할 것으로 사료된다.

119 구급대원의 직접의료지도 이용경험과 관련요인

주미현,한미아 한국화재소방학회 2016 한국화재소방학회논문지 Vol.30 No.3

직접의료지도란, 현장에서 환자에게 응급처치를 수행하거나 이송하는 구급대원이 의사에게 전문적인 지도와 자문을 제공받는 행위를 말한다. 본 연구는 직접의료지도의 이용 실태를 파악하고 관련요인을 조사하고자 실시되었다. 광주광역시에 근무하고 있는 119 구급대원 153명을 연구대상으로 하였고, 자기기입식 설문조사를 이용하여 자료를 수집하였다. 통계분석은 SAS version 9.3을 이용하였다. 연구대상자 중 약 82%가 최근 한 달 이내 직접의료지도 경험이 있었고, 다중로지스틱 회귀분석 결과 기혼자인 경우(OR = 3.87, 95% CI = 1.22~12.27), 1급 응급구조사인 경우(OR = 2.87, 95%CI = 1.02~8.09), 심혈관계 응급환자를 처치한 경우(OR = 9.19, 95% CI = 1.87~45.08)에 직접의료지도 이용에 대한 교차비가 유의하게 높았다. 따라서 향후 직접의료지도 내용과 제도 개선 시 119 구급대원의 특성과 처치하는 환자의 질병상태를 고려한다면 직접의료지도 활성화에 도움이 될 것이다. Medical oversight (MO) means the advice and direction provided by a physician to rescue workers who provide medicalcare or carry patients at the scene of an emergency. The purpose of this study was to investigate the utilization of MOand related factors among some 119 rescue workers in Gwangju. A self-reported questionnaire was completed by 153 rescueworkers in these 119 safety centers. The data were analyzed by SAS version 9.3. Overall 82.4% of the subjects utilizedMO during the past month. In the multiple logistic regression analysis, the married subjects (OR = 3.87, 95%CI = 1.22~12.27), level 1 emergency medical technicians (OR = 2.87, 95% CI = 1.02~8.09), and subjects who treated cardiovascularemergency patients (OR = 9.19, 95% CI = 1.87~45.08) had significantly higher odds ratios for the utilizationof MO. The experience of MO accounted for 82%. The development of strategies and education plans taking these resultsinto consideration will help to improve the utilization of MO.

다른 월경주기상태를 지닌 여자 운동선수들에서 급성운동이 혈중 산화스트레스 지표에 미치는 영향

주미현,유상호,최희남 대한임상건강증진학회 2007 Korean Journal of Health Promotion Vol.7 No.3

담뱃값 인상에 따른 고혈압 환자의 흡연감소 및 관련요인

주미현 ( Mi Hyun Joo ),한미아 ( Mi Ah Han ),박종 ( Jong Park ),최성우 ( Seong Woo Choi ),류소연 ( So Yeon Ryu ),신준호 ( Jun Ho Shin ) 한국보건정보통계학회(구 한국보건통계학회) 2019 보건정보통계학회지 Vol.44 No.1

Objectives: The price of tobacco is an important factor affecting the smoking behavior. The Korean government raised the price of tobacco by 80% from 2,500 won to 4,500 won in 2015. This study investigated the change of smoking behavior after the price raise of tobacco in hypertension patients. Methods: The analysis used the data from the third year of the National Health and Nutrition Examination Survey (2015), which examined the changes in smoking habits after cigarette price hikes. Of the adults aged 19 years and older, 958 were currently smokers and 79 of the former smokers who quit smoking less than one year, excluding those who quit smoking before the cigarette price increase, total 1,037. In 193 hypertensive patients, 193 non-hypertensive patients were selected by 1:1 age group, and a total of 386 patients were analyzed. Data were analyzed using SAS 9.3 statistical program and chi-square and multiple logistic regression analysis. Results: The smoking reduction rate was 46.6% in the hypertensive group and 44.6% in the non-hypertensive group. There was no significant difference between the two groups (p=0.683). Multivariate logistic regression analysis showed that factors affecting smoking cessation in hypertensive group were stress level, smoking prevention and smoking cessation education. In the hypertensive group, the odds ratio was 3.16 (95% CI, 1.39-7.18) in the normal range, If you receive less than the no-smoking education, the statistical significance is 4.17 (95% CI, 1.15-15.12). Conclusions: In the future, there will be a variety of measures such as the government’s continuous cigarette price increase policy, active support for stress management in hypertensive patients, and the introduction of practical policies through socio-economic approaches would be effective in reducing smoking rates in hypertensive patients.

장기간의 유산소성 운동이 총 콜레스테를, 중성지방, 혈당 및 폐환기 기능에 미치는 효과

주미현(Mi-Hyun Joo),최희남(Hee-Nam Choi) 한국체육과학회 1994 한국체육과학회지 Vol.3 No.2

복합운동프로그램이 마른비만 여자대학생들의 신체조성, 혈중 지질, 체력 및 심리적 요인에 미치는 영향

주미현(Mi-Hyun Joo) 한국생활환경학회 2012 한국생활환경학회지 Vol.19 No.5

The purpose of this study was to investigate the effect of multicomponent exercise program on body composition, physical fitness, blood cholesterol, physical self-efficacy and health-related quality of life in thin-obesity college women. Thirty female students were assigned to an exercise group(n = 15) and a control group(n = 15). Exercise group participated in multicomponent exercise program for 70minutes/day and 3day/week for 12 weeks, whereas control group was asked to maintain normal lifestyle during the same intervention period. Variables related to body composition, physical fitness, blood cholesterol, physical self-efficacy and health-related quality of life(SF-36 questionnaire is used) were measured before and after multicomponent exercise program. The results of this study were as follows: Weight, %body fat, BMI and WHR decreased significantly and HDL-C increased significantly in exercise group. VO2max, grip strength, sit-up, side step, sit and reach and standing long jump increased significantly in exercise group. Physical functioning, Mental health and General health in the SF-36 questionnaire increased significantly in exercise group. The 12 weeks multicomponent exercise program indicated beneficial effects such as a decrease of weight, %body fat, BMI and WHR, and an increase of HDL-C, physical fitness and health-related quality of life in exercise group. Therefore, this multicomponent exercise program is considered to be good for the health care of thin-obesity college women.

한국 20대의 비타민 D 결핍 관련요인 분석

주미현(Mi-Hyun Joo),이산휘(San-Hui Lee),이윤경(Yun-Kyung Lee),류소연(So-Yeon Ryu) 한국산학기술학회 2018 한국산학기술학회논문지 Vol.19 No.5

본 연구의 목적은 ‘국민건강영양조사 제 5기(2010-2012)’ 자료를 이용하여 만 20-29세 연령의 한국인에서의 비타민 D 수준과 비타민 D 결핍관련요인을 알아보고자 하였다. ‘국민건강영양조사 제 5기(2010년-2012년) 완료자중에서 비타민 D 결측치가 없는 만 20세 이상 만 29세 미만 1,837명을 대상으로 분석하였다. 사용된 데이터는 가중치가 적용된 복합표본분석을 이용하여 카이제곱검정 및 다중로지스틱 회귀분석으로 분석하였다. 20대의 84.2%가 비타민 D 결핍으로 조사되었으며 여성이 88.6%로 남성 79.4%보다 높은 결핍률을 보였다. 다중 로지스틱 회귀분석 결과, 비타민 D 결핍에 대한 위험도가 여성인 경우(OR 1.84; 95% CI 1.31-2.56), 미혼인 경우(OR 2.12; 95% CI 1.41-3.19), 주관적 건강상태가 나쁨인 경우(OR 1.94; 95% CI 1.16-3.25) 그리고 중등도 이상 신체활동을 하지 않는 경우(OR 3.38; 95% CI 1.85-6.16)에 높았다. 불확실한 미래를 위해 다양한 노력과 활동을 하는 20대의 비타민 D 결핍은 개인적으로나 사회적으로 매우 중요한 건강문제로 영향을 주기때문에 이 시기의 비타민 D 수준에 대한 지속적인 연구가 필요할 것이다. 또한 비타민 D는 햇빛에 노출되는 시간과 신체활동여부와 밀접한 관련이 있는 것으로 나타나 20대의 야외활동 및 중등도 이상의 신체활동을 할 수 있는 학교 및 직장 내 기반시설을 조성하는 등 국가차원에서의 장기적이고 계획적인 노력이 필요하리라고 생각된다. The aim of this study was to investigate vitamin D status and factors associated with vitamin D deficiency among Koreans in their using Korean National Health and Nutrition Examination Survey (KNHANES) V. The subjects were 1,837 people who were 20-29 years old. The data were analyzed by χ² test and multiple logistic regression analysis using weighted composite sample analysis. Vitamin D deficiency was reveled in 84.2% of subjects; 88.6% of women and 79.4% of men showed deficiency. In the multiple logistic regression analysis, the risk for vitamin D deficiency was higher in women (OR 1.84; 95% CI 1.31-2.56), non-married (OR 2.12; 95% CI 1.41-3.19), poor subjective health status (OR 1.94; 95% CI 1.16-3.25), and in the absence of moderate to vigorous physical activity (OR 3.38; 95% CI 1.85-6.16). Continued research on vitamin D levels at this time is needed since vitamin D deficiency among Koreans in their twenties will exacerbate health problems, both individually and socially. In addition, vitamin D has been shown to be closely related to time of exposure to sunlight and physical activity. Therefore, it is thought that long-term and planned efforts should be made at the national level, such as establishing schools and workplaces in which those in their twenties can perform outdoor activities and moderate to vigorous physical activity.

유산소운동이 여자대학생의 신체구성, 심폐지구력 및 혈중 산화스트레스 지표에 미치는 영향

주미현(Mi-Hyun Joo),유인영(In-Young Yoo) 한국생활환경학회 2011 한국생활환경학회지 Vol.18 No.1

The purpose of this study was to investigate the effects of aerobic exercise program on body composition, cardiorespiratory fitness, and blood oxidative stress markers of university female students. Twenty-one female students were assigned to an aerobic walking training group (n = 11) and a control group (n = 10). Exercise group participated in walking exercise program for 60 minutes/day and 3 dayweek for 12 weeks, whereas control group was asked to maintain normal lifestyle during the same intervention period. Variables related to body composition, blood pressure, heart rate, VO₂max and blood oxidative stress markers (serum MDA, BAP) were measured before and after walking exercise program. The results of this study were as follows: No significant changes were found in variables regarding the body composition, blood pressure and heart rate in exercise group and control group. VO₂max increased significantly in exercise group (P<.001). MDA decreased significantly (P<.05) and BAP increased significantly (P<.05) in exercise group. The 12 weeks aerobic walking program indicated beneficial effects such as increase cardiorespiratory fitness and decrease oxidative stress in exercise group. The 12 weeks aerobic walking program indicated beneficial effects such as increase cardiorespiratory fitness and decrease oxidative stress in exercise group.

건강도시사업 실행단계의 국제간 비교

주미현(Mi Hyun Joo),김한중(Han Joong Kim) 한국간호행정학회 1999 간호행정학회지 Vol.5 No.3

과천시민의 고혈압 인지, 치료, 조절과의 관련요인

최연희,남정모,주미현,문기태,심지선,김현창,서일,Choi, Youn-Hee,Nam, Chung-Mo,Joo, Mi-Hyun,Moon, Ki-Tae,Shim, Jee-Seon,Kim, Hyeon-Chang,Suh, Il 대한예방의학회 2003 예방의학회지 Vol.36 No.3

Objectives : To identify the factors related to awareness, treatment, and control of hypertension in a Gwacheen population. Methods : This study surveyed 1,176 Gwacheon residents older than 40 years, and measured blood pressure using a standardized guideline in 1999. The study subjects were 473 adults (175 males, 295 females) with hypertension defined as a systolic blood pressure $\geq$140 mmHg, diastolic blood pressure $\geq$90 mmHg or reported treatment with antihypertensive medication. Information on awareness, treatment, and control of hypertension, and sociodemographic and health-related factors .was collected through person-to-person interviews with a structured questionnaire. Results : Overall, 252 (53.3%) of hypertensive subjects were aware of their condition, of whom as many as 193 (76.6%) were being treated, and 81 (42.0%) had their blood pressure controlled at the recommended level (<140/90 mmHg). However, of the 473 subjects found to have hypertension, only 40.8% were being treated, and 17.1% were under control. There were no significant differences in the proportions of awareness, treatment, and control of hypertension. In multiple logistic regression models, awareness of hypertension was positively associated with age and family history of hypertension in females. Control of hypertension was also positively associated with haying a partner and marital status in females.. Conclusion : These findings demonstrate that much greater efforts on improving awareness, treatment, and control of hypertension are needed, even in urban community settings, considering related factors such as a9e, family history, and marital status. However, these factors should be further investigated for their causal relationship.