鷄胎器官 成長에 미치는 Testosterone의 效果에 對하여

朱剛,郭外景,金達洙,朴洋奎 慶北大學校 醫科大學 1967 慶北醫大雜誌 Vol.8 No.2

탄성 Braid의 특성에 관한 연구(II) ―탄성 Braid의 제조조건에 의한 특성변화―

주강,곽영식,Choo, Kang,Kwag, Young-Sig 한국섬유공학회 1985 한국섬유공학회지 Vol.22 No.4

Dependence of physical properties on manufacturing conditions of cotton elastic braid made of core latex rubber thread were studied experimentally. The results as follows; 1) Breaking strength had little effect on braiding angle($\theta$a), and elongation was proportional to tan $\theta$a. 2) Relation between limiting elongation and strain ratio of core latex rubber thread showed a linear function of which slope coresponds to a draft ratio in manufacturing process(Da). 3) Tensile stress was depended on $\theta$a. 4) Stress relaxation behaviour of the elastic braid satisfied the stress relaxation equation of polymerec elastomers as shown below. ln ft=lnfto-K ln n Where K values, rate of stress relaxation of the elastic braid, can be expresses as; K=(0.1101-0.7763u)k When considered the strain ratio of rubber thread, from this equation, calculation of the stress relaxation rate(k) of rubber thread enables the estimation of tensile stress at any time.

탄성 Braid의 특성에 관한 연구(I) ―탄성 Braid구조의 기하학적 이론―

주강,곽영식,Choo, Kang,Kwag, Young-Sig 한국섬유공학회 1985 한국섬유공학회지 Vol.22 No.4

An equation of structural changes in stretching cotton elastic braid was derived by modeling a structure of cotton elastic braid consisting of latex rubber thread as core material, and the structure changes under manufacturing conditions and the effect of the changes on the physical properties were studied. The results obtained are summarized as follows; 1) The strain ratio of the core rubber thread(u) is dependent upon spiral length ratio(${\beta}$). In other words, the strain ratio is dependent upon manufacturing braiding angle($\theta$a), manufacturing drafting ratio(Da) and diameter ratio of covering yarn to core rubber thread ($\phi$). ${\mu}$ shows large values when $\theta$a is decreased to maintain uniformity approaching D=1, and the strain ratio decreases linearly with increasing tan $\theta$a. and the width decreases significantly and the braiding angle decreases linearly, respectively depending upon the drafting ratio of the braid(DB). 3) Results from comparison of the theoretical equations(4) and (8) for width and braiding angle with the experimental values approach the theoretical equation when drafting ratio of core rubber thread(D) and $\theta$a increase. It is anticipated that this fact may be caused by the effect of ${\beta}$. 4) When the structural changes of the elastic braid are considered on the basis of the conception of coefficients of width change(Kw) and braiding angle change(K$\theta$), Kw is dependent upon $\theta$a and K$\theta$ is independent upon both $\theta$a and $\phi$. 5) When the Da is constant, linear relation between K$\theta$ and Kw/D is established and its slope corresponds to Da, nearly coinciding with the experimental curves in Fig. 16. 6) Estimated equations(12) for the manufacturing braiding angle shows optimum conditions within ranges of $\phi$=0.40 to 0.47 and $\theta$a=20$^{\circ}$ to 25$^{\circ}$.

대화는 내가 먼저

주강 단국대학교 1992 누에고치 Vol.14 No.-

포스터 전시 발표 : 내분비-대사 ; 당뇨병성 케톤산증으로 발현된 MELAS (mitochondrial encephalomyopathy, Lactic acidosis, and stroke-Like episodes) 증후군 1예

주강,김은정,이정록,임소희,홍창균,고승현,윤건호,송기호,박성경 대한내과학회 2002 대한내과학회 추계학술대회 Vol.63 No.-

^3H-thymidine 標識率로 본 松果體 細胞의 動態

朱剛,張性翼 慶北大學校 醫科大學 1977 慶北醫大誌 Vol.18 No.2

pinealocyte에서는 표지세포가 ^3H-thymidine주사 후 9시간에서 11시간에 약간 나타났으나 거의 없었다. supporting cell에서는 주사 후 3시간 후에 표지세포가 出現하고 11시간까지는 점차 증가하다가 13시간 후에는 없어졌다. 그러나 주사 후 21시간 이후에는 다시 출현하였다. 이로 미루어 보아 pinealocyte의 分化, 증식은 主로 胎生期에 그리고 supporting cell은 生後에 활발히 증식할 것으로 생각 된다. The number of labeling cells of pinealocytes and supporting cells were counted with an hours interval to estimate the cell behavior of the pineal body in one day postnatal chick. After injection of ^3H-thymidine, there were few labeling cells in the pinealocytes except for somewhat appearing form 9 to 11 hours. The appearance of the labeling cells in the supporting cells quite differed from that of pinealocytes. They showed great increasing immidiately at 3 hours after injection, and gradual increases were seen till 11 hours then they were not seen at 13 hours. However, they reappeared at 21 hours after injection. These data, therefore, suggest that the differentiation and proliferation of the pinealocytes would chiefly be occured in a certain stage of the fetal life and there would be an active proliferation of the supporting cells during a stage of post-natal chick.

흰 쥐 腦의 梨狀葉에서의 Cholecystokinin-Octapeptide 陽性神經元의 形態學的 特徵 : 免疫組織化學法에 의한 光學 및 電子顯微境的 硏究 A Correlated Light and Electron-Microscopic Study

주강,김은희,조희중 慶北大學校 醫科大學 1988 慶北醫大誌 Vol.29 No.1

흰 쥐 腦의 梨狀葉에서 CCK-8함유 신경원의 형태학적 특징을 알기 위하여 peroxidase antiperoxidase 법을 행한 다음 광학 및 전자현미경으로 관찰한 결과를 요약하면 다음과 같다. 1. CCK-8양성반응물질은 신경원내에 존재했으며 CCK-8양성 신경세포체 및 양성신경섬유는 이상엽의 제Ⅱ, 제Ⅲ층의 순으로 많이 관찰되었으며 제Ⅰ층에는 거의 분포하지 않았다. 2. CCK-8양성신경원은 bipolar, bitufted, multipolar 및 비전형적인 semilunar type으로 나눌 수 있었고 bipolar type이 가장 많았다. 3. 이상엽의 이러한 CCK-8양성신경원은 전자현미경으로 관찰해 보면 대부분의 경우 함입된 핵을 가지며, 세포체 및 수상돌기에 공히 대칭형 및 비대칭형의 synapse를 가지는 것으로 보아 비원추형세포에 속하는 개재신경원으로 생각되어진다. 4. CCK-8양성신경종말은 비양성의 multipolar, semilunar 및 pyramidal cell등과 대부분 대칭형의 synapse를 형성하였고 양성의 bipolar, bitufted 및 multipolar cell등과도 대칭형의 synapse를 이루었다. 5. 대칭형의 synapse를 이루는 CCK-8양성신경종말은 적어도 이상엽의 bipolar cell에서 기시함이 관찰되었다. Based upon the results of immunohistochemical studies, high concentration of cholecystokinin octapeptide (CCK-8) immunoreactive neurons was identified in the cerebral cortex. Among the cortex, piriform cortex, which is one of the centers of the limbic system and is very different anatomically and physiologically from the neocortex, was observed to have greater accumulation of CCK-8 immunoreactive structures. In the present study, CCK-8 immunoreactive neurons in the rat piriform cortex were studied by correlated light and electron microscopy using the perosidase antiperoxidase immunocytochemical technique. The results obtained were as follows: CCK-8 immunoreactivity was localized in nueronal perikarya and processes, and CCK-8 immunoreactive neurons and axon terminals were observed in layer Ⅱ and Ⅲ of the piriform cortex. However, they were more frequent in layer Ⅱ. CCK-8 immunoreactive nuerons observed were of four types: bipolar, bitufted, multipolar and atypical semilunar cells Among them, bipolar cells were observed most frequently. Electron microscopy showed CCK-8 immunoreactive neurons to have an indented nuclei and synapses, both symmetrical and asymmetrical, on their perikarya which is additional evidence favoring the interpretation that they are non-pyramidal interneurons. The majority of axon terminals displaying CCK-8 immunoreactivity formed symmetrical synapses with non-reactive multipolar, semilunar and pyramidal cells and, less frequently, with immunoreactive bipolar, bitufted and multipolar cells. CCK-8 immunoreactive bipolar cells are thought to be the origin of some of the CCK-8 immunoreactive axon terminals which have symmetrical synapses.

Cortisone의 鷄胎器官成長에 미치는 影響에 對하여

朱剛 慶北大學校 醫科大學 1967 慶北醫大誌 Vol.8 No.1

This study is to observe the effects of cortisone on the weight gains of body and various organs of chick embryo, out of which growth and relative growth formula has been derived. On the 8th and the 12th days of incubation, 0.5㎎ and 2.0㎎ of cortisone were injected into the chorioallantoic membrane of each incubated egg of two groups. Between the 12th and 18th of Incubation days, a daily total of 10 treated eggs was broken for weighing the body weights of chicks embryos and six organs-brain, eye ball, heart, lung, liver, and kidney. The effects of doses and difference of injection times on growth were analyzed by the Repeated Two Way Layout Method, and the determination of the significance in the levels of difference was made by the Turkey's Method. The formulas applied to analyzing the changes in growth are: y=a+bt+ct^2, coefficient of relative growth (α) by y=bxα. y= growth quantity of organs; t= specific date of incubation period, x= body weight; a,b,c=constants. The results are summarized as follows: (1) When injected with cortisone acetate, the chick embryos were observed with remarkable growth inhibition(p<0.01). (2) The growth inhibition appeared to be much stronger with the group of 2.0㎎ dosage than that of 0.5㎎ dosage. No noticeable differences were observed on the liver of the 8th day group, and on the kidneys of the 12th day group. (3) Generally, the growth inhibition was found stronger on the 8th day group than on the 12th (p<0.01), but in brain and eye balls, no inhibitory difference depending on the injection days was observed. Lungs were unique in that the growth inhibition appeared in the 12th day group (p<0.01). (4) Growth rate: In the 8th day group, the growth rate was observed to be increased in body weight, lungs, liver, and kidneys throughout the two injected groups- 0.5㎎ and 2.0㎎: brain and heart, however, showed the increase only in 2.0㎎ injected group. The growth rate was observed decreased in eye balls of two injected groups; the decrease of brain and heart were in 0.5㎎ injected groups. In the 12th day group, the increase in growth rate was shown in the followings: body weight, eye balls and lungs of 0.5㎎ injected group, body weight, eye balls and kidneys of 2.0㎎ injected group, the other organs except the increased ones showed decrease in all injected groups. (5) Specific Growth Rate: (a) In the 8th day group: 1) increase was observed only in lungs, 2) decrease was in all organs except lungs. (b) In the 12th day group: 1) increase eye balls of 2.0㎎ injected group; kidneys of 2.0㎎ group. 2) decrease was in the other organs except the above mentioned. (6) The Growth Gradient: The growth centers appeared as follows: (a) In the 8th day group: lungs of all two injected groups, on the 18th day of incubation; liver of 2.0㎎ injected group, on the 15th; kidneys of 0.5㎎ injected group, 17th day of incubation; the others all appeared on the 12th day. (b) In the 12th day group: brain, heart and liver of 0.5㎎ injected group had the growth centers on the 12th incubation day, and the others had them on the 18th incubation day. (7) The Coefficient of Relative Growth: The coefficient of relative growth was observed as follows: (a) In the 8th day group: the liver of two injected group, and kidneys of 0.5㎎ injected group were of positive allometry; the others showed negative. (b) In the 12th day group: liver of two injected groups and heart and kidneys of 2.0㎎ injected group were positive, while the others were negative.

Cell Cycle에서 ^3H-thymidine 標識指數와 分裂指數가 일치하지 않는 原因

朱剛 慶北大學校 醫科大學 1978 慶北醫大誌 Vol.19 No.2

cycle에서 標識指數와 分裂指數가 일치하지 않는 원인을 알고저 Shaver種白色 Leghorn 수평아리를 오전 오후 실험군으로 나누어 3가지 方法에 의해서 검토한 결과 다음과 같은 성적을 얻었다. 1. 分裂指數와 標識指數는 一致하지 않았다. 2. 世代時間(generation time)도 理論的 방법에 따라 實測値와 많은 차이가 있었으나 本人의 方法이 가장 實測値에 가까웠다. 3. 標識指數와 分裂指數가 一致하지 않는 原因의 한가지 說明으로서 圖 4에 提示된바와 같은 model를 설정하였다. The rate of cell prolferation and cell specialization are influenced by a wide variety factors in the microenvironment of the cell pepulation. the development of definitions of kinetic parameters related to cell proliferation, and the collection of quantitative data to estimate a few of the parameters, has facilitated the development and use of simplified ideal proliferative systems or models. Some of the methods to estimate compartive rate of cell proliferation in the renewing populations of the gstrointestinal tract, have used the ratio of the number of cells in DNA synthesis(S) or mitosis(MI), to the duaration of DNA synthesis (TG) or mitosis (TM), and have noted limitations of the estimate. The cell cycle duraration has also been approximated by observing the time between successive waves of labeled mitoses after administration of tritiated thymidine. In the present analysis tritiated thymidine autoradiography has been applied to the esophageal epithelial cell pouplation in two groups of male chicks, and then, comparative rates of cell proliferation were determined by observing the appearance of successive waves of labeled mitoses. In addition, the theoretical models were compared to experimental data, in an attempt to gain further insight into nature of the differences between theable llring indeses and mitotic indeces. Theoretically all the cells which undergo DNA duplication should divide so that lagelling indeces is in proportion to mitotic indeces ineach cell population. The result of many studies, however, tend not to be this theory. It seemed that all the and M. pahse, cells which completed DNA duplication do not necessarily enter the mitotic phase directly. The auther, therefore propsed another GO which tentatively between S pahse and M pahse, celled GO_2 and accordingly traditional GO is called GO.

포스터 전시 발표 : 소화기 ; Sump 증후군에 의한 간농양과 위장으로 자발성 농양배액 1예 (초)

주강,하창윤,임병렬,신민기,이창민,장현정,민현주,김태효,정운태,이옥재 대한내과학회 2008 대한내과학회지 Vol.75 No.1S