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21-Hydroxylase결핍의 선천성 부신증식증에 의한 여성반음양 치험 1 예
주갑순,김해중,박상진 대한산부인과학회 1990 Obstetrics & Gynecology Science Vol.33 No.4
위와 같이 CAH중 Heterozygous 21-hydroxylase의 결핍으로 인한 것으로 사료되는 여성 반 음향 1례를 치험하였기에 간단한 문헌 고찰과 함께 보고하는 바이다. Female hermaphroditism is a condition in which individuals with a 46, XX chromosomal constitution differentiate partially as phenotypic males, usually manifesting masculinization of the external genitalia. Most female hermaphrodites have one of the types of congenital virilizing adrenal hyperplasia. Congenital adrenal hyperplasia is an inborn error transmitted by an autosomal recessive gene and may be due to a defect in any of the enzymic steps in the biosynthesis of cortisol. Most affected individuals have a failure of 21-hydroxylation which prevents the conversion of 17-hydroxyprotesterone to 11-deoxycortisol. A defect in 21-hydroxylase leads not only to inefficient formation of cortisol but also to excessive production of adrenal androgens causing virilization. A case of female hermaphroditism due to congenital adrenal hyperplasia is presented with a brief review of the literature.
주갑순,박용균,조수용,서호석,허준용,이도근,박석진 대한산부인과학회 1991 Obstetrics & Gynecology Science Vol.34 No.6
최근 본원에서 무심장기형을 동반한 다태임신 3예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. The acardic anomaly is very rare congenital anomaly, which is associated with a monozygotic twin pregnancy. We experienced 3 cases of acardiac anomalies, and these cases were presented with a brief review of the literatures.
주갑순,박용균,조수용,서호석,허준용,이경호 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.12
본 례는 임신초기에 산전진찰중 우연히 발견된 직경 30cm의 거내난소낭종을 가진 28세의 임산부에서 초음파로 양성 종양이라고 진단한 후 임신 13주에 우측 난소난관절제술을 시행하고 병리조직학적 검사상 양성 장액성 낭종으로 판명된 증례로, 저자들은 간단한 문헌적 고찰과 함께 보고하는 바이다. We report a case of huge ovarian cyst in nulliparous, primigravida, 28-years old woman during intrauterine pregnancy. This tumor was measured 30*25*13 cm in size, and the volume of the cystic contents was 51. The pathologic diagnosis was serous cystadenoma, right ovary. The case will be presented in more details with a brief review of literature.
주갑순,서호석,조수용,허준용,박용균 대한부인종양 콜포스코피학회 1993 Journal of Gynecologic Oncology Vol.4 No.4
Fourty three patients known to have cervical intraepithelial neoplasia were assigned to Papanicolaou smear in five different ways, i, e, A) cotton tipped wood applieator at the pasterior vaginal fronix and the ectocervix, B) cotton tipped wood applicator at the ectocervix and the endocervical canal, C) Cytohrush at the endocervical canal, D) Cervexbrusk and E) Cyto-spatula. At the completion of cytologic study, all the subjects were done colposcopically directed biopsy and/or ECC. To evaluate the false negative rates of the cytologic test, cervical cone biopsy or hysteectorny was performed on all the patient., The false negat,ive rates were 53.5% in A) 39.5% in B), 14,0% in C), l8.6% in D), 25.6% in E) and statistical differences occurect between each group, It was also found that bleedings were most frequently endountered in E) and the encocervical cells were most frequently appeared in C). With these results, it can he stated that the rate of negative encocervical cells in the srnear were correlated with the false negative rates of cervical cytology.
부인암 환자에서 골반경을 이용한 대동맥 주위 림프절 절제술의 임상적 유용성에 관한 연구
주갑순,박용균,조수용,서호석,허준용,이재관,김철용 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.2
Accurate evaluation of para-aortic lymph node metastasis is important in planning treatment of gynecologic malignancies. For example, geographic treatment failure can be prevented by accurate staging in advanced cervical cancer. The objective of this study is to investigate the feasibility of laparoscopic para-aortic lymph node dissection as a staging procedure in patients with gynecologic malignancies. Eight patients had underwent laparoscopic para-aortic lymph node dissection from May, 1995 to August, 1996. The average operative time was 141 minutes and the mean estimated blood loss was 260 ml. An average of 5.9 lymph nodes was retrieved. Hospital stays ranged from 2days to 3days, with an average of 2.1days. There were no serious complications. Nodal metastasis was diagnosed in one patient whom had negative findings in computerized tomography(CT)scans prior to surgery. In conclusion, laparoscopic para-aortic lymph node dissection appears to be a safe and feasible staging procedure for the patients with gynecologic malignancies and it is an attractive and alternative to traditional surgical staging.
호르몬 대체요법시 Dydrogesterone이 지질대사 및 골대사에 미치는 영향
주갑순,박용균,조수용,서호석,허준용,이재관,이갑노,임인수 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.5
The addition of a monthly course of progesterone decrease the incidence of endometrial hyperplasia and endometrial carcinoma. The progesterones used in hormonal replacement therapy(HRT) differ markedly in their progesteronic, androgenic and even estrogenic activities. These characteristics may influence both symptomatic and metabolic side effects. The purpose of this study was to examine effect of bone and lipid metabolism in postmenopausal women treated with conjugated equine estrogens plus dydrogesterone. A total 131 postmenopausal women(surgical menopause=95, natural menopause=36) and not-treated postmenopausal women(control=22) were invited to participate in this study. Patients were divided into groups which had received conjugated equine estrogen(CEE) 0.625 mg/day 21-day-cycle each month(n=20), CEE 0.625 mg/day plus Dydrogesterone 10 mg/day 10-day-cycle each month(n=111), and no treatment control group(n=20). Serum lipid & lipoprotein(Triglyceride, Total cholesterol, High density lipoprotein, Low density lipoprotein) and serum osteocalcin, urinary Deoxypyridinoline were examined in all patients. There were no significant differences in bone & lipid metabolism between CEE and CEE plus Dydrogesterone groups. In conclusion, Dydrogesterone may be used safely in postmenopausal women without Metabolic side effect.
주갑순,박용균,조수용,서호석,허준용,이광호,강준구,정경우 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.9
This study was taken at the Department of Obstetrics and Gynecology, college of Medicine, Korea University, to investigate the association between some of the risk factor and the incidence of fetal growth retardation. The retrospective survey of obstetric records of 4887 delivery, who were admitted between 1992 and 1994, was carried out in Korea University Medical Center. The results were as follows: 1. IUGR was 215 births(4.56%) in 4,709 births for 3 years. 2. 53% of IUGR was unknown cause, 46.9% of IUGR was known. Among 46.9%, maternal factor was 78.2%, Placenta factor was 19.8%, fetal anomaly was 4%. 3. Among maternal factor, PIH was the most common cause(64.5%).