점액성 악성 섬유조직구종에 관한 면역 조직화학적 연구 : Histogenesis

조해창,전호종 中央醫學社 1988 中央醫學 Vol.53 No.9

The malignant fibrous histiocytoma (MFH) is the most common soft tissue sarcoma in adult life. The cellular origin of MFH claimed that the tumor originates from tissue histiocyte which may undergo transformation to a facultative fibroblast. Others suggest that a primitive mesenchymal cell gives rise to two cell lines, one revealing histiocytic and the other showing fibroblastic differentiation. This MFH shows a broad range of histological appearance, so it is divided into the several subtypes: storiform-pleomorphic, myxoid, giant cell, inflammatory and angiomatoid. The myxoid form of MFH is characterized by myxoid areas in association with cellular areas indistinguishable from typical MFH. This is a case report of myxoid malignant fibrous histiocytoma, arising in the right lower extremity of 66 year old male patient. The patient was taken first operation "below knee amputation" under impression of MFH (1988. March), but recurrence was developed about 2 months after (1988. May). He was taken above knee amputation. The specimens were myxoid, lobulated and bulky neoplastic tissue overlying skin, measuring 15xl0x9 cm and weighting 850 gm. Cut surface show typical fish flesh appearance and multifocal hemorrhagic necrosis. The prominent microscopic findings show extensive myxoid areas revealing widely spaced spindled & pleomorphic cells in a matrix of acid mucopolysacchaide. The immunohistochemical staining for ai -antitrypsin, ai -antichymotrypsin, lysozyme and C3 receptor were negative, but vimentin was positive. These results were hightly suggested that the cellular origin of the myxoid MFH is not a histiocyte.

저산소-재산소화 손상에 미치는 Nitric Oxide와 항산화제의 상호작용

조해창,손영길,김광일,이정안,배병조 대한외과학회 2002 대한외과학회 학술대회 초록집 Vol.2002 No.5

장관 손상으로 확진된 범발성 복막염에 대한 임상적 고찰

조해창,전성윤,배병조,유동걸,손영길,이정안 대한외상학회 2001 大韓外傷學會誌 Vol.14 No.1

Background: Generalized peritonitis in abdominal trauma patients is a common disease entity. An injury of the hollow viscera is the major cause of traumatic generalized peritonitis, so it is necessary to study clinical analysis of traumatic generalized peritonitis caused by hollow visceral injury. The aim of this study is to help early diagnosis and appropriate treatment by evaluating patients with traumatic generalized peritonitis. Materials and Methods: We evaluated 76 patients with generalized peritonitis caused by hollow visceral injury after abdominal trauma who had undergone a laparotomy in the Department of General Surgery, Daegu Fatima hospital, from January 1996 to December 2000. The authors reviewed their medical and operation records retrospectively. Results: The results are as follows: 1) The most common ages were in the 3rd, 4th, 5th, and 6th decades (82.9%). There were 59 males and 17 females (M : F=3.5 : 1). 2) the generalized peritonitis caused by hollow visceral injury after abdominal trauma was due to blunt trauma in 45 (59.2%) patients and penetrating trauma in 16 (21.1%) patients. The most common injured organ was the small bowel (53 patients, 69.7%). 3) The most common symptom and sign were abdominal pain (89.4%) and abdominal tenderness (93.4%), followed by rebound tenderness, abdominal distension, and wound pain. 4) There was a leukocytosis in 54 (71.1%) patients. 5) Abdominal CT (72.3%) and simple abdomen (65.8%) was performed for appropriate diagnosis. 6) Sixty-three (63) patients (82.9%) were operated on within 12 hours from injury. 7) The incidence of blood transfusion was more common in penetrating trauma (56.3%). 8) GIT perforation alone occurred in 34 (44.7%) patients. 9) Except for the hollow visceral organ, the most common associated intraabdominal injured organ and extraabdominal injured organ were the mesentery and the pelvis, respectively. 10) The primary repair in 48 (63.2%) patients more commonly involved hollow visceral injury. 11) The most common complications were infection and retension abscess which in 4 (5.3%) patients each. 12) The mortality rate was 3 (3.9%) patients, and the cause of injury in those case, was blunt trauma. Conclusion: We suggest that early diagnosis and speedy transfer are needed in traumatic generalized peritonitis patients. According to the surgical indication, operative treatment should occur as soon as possible to reduce morbidity and mortality in such patients.

Open Herniorrhaphy

조해창 대한외과학회 2019 대한외과학회 학술대회 초록집 Vol.2019 No.5

후복막강에서 기원한 염성 섬유 조직구종 : 1례 보고 Report of A case

조해창,전호종 최신의학사 1988 最新醫學 Vol.31 No.8

Remaining service life estimation of reinforced concrete buildings based on fuzzy approach

조해창,이득행,주현진,김강수,김기현,Paulo J. M. Monteiro 사단법인 한국계산역학회 2015 Computers and Concrete, An International Journal Vol.15 No.6

The remaining service life (RSL) of buildings has been an important issue in the field of building and facility management, and its development is also one of the essential factors for achieving sustainable infrastructure. Since the estimation of RSL of buildings is heavily affected by the subjectivity of individual inspector or engineer, much effort has been placed in the development of a rational method that can estimate the RSL of existing buildings more quantitatively using objective measurement indices. Various uncertain factors contribute to the deterioration of the structural performance of buildings, and most of the common building structures are constructed not with a single structural member but with various types of structural components (e.g., beams, slabs, and columns) in multistory floors. Most existing RSL estimation methods, however, consider only an individual factor. In this study, an estimation method for RSL of concrete buildings is presented by utilizing a fuzzy theory to consider the effects of multiple influencing factors on the deterioration of durability (e.g., concrete carbonation, chloride attack, sulfate attack), as well as the current structural condition (or damage level) of buildings.

Structural Safety Inspection of Reinforced Concrete Structures Considering Failure Probabilities of Structural Members

조해창,이상훈,최승호,이성태,강원희,김강수 한국콘크리트학회 2023 International Journal of Concrete Structures and M Vol.17 No.3

Regular safety inspections of existing reinforced concrete (RC) structures are required according to the regulations and criteria set by each country. In South Korea, the safety inspection regulations provided by the Korea Infrastructure Safety and Technology Corporation (KISTEC) are followed. These regulations were developed based on fuzzy theory to avoid subjective decisions, and provide standardized deterioration grades for member types, floors, and the entire structure. However, the safety inspection regulation by the KISTEC often provides unconservative evaluation results. In particular, as the importance factors of beam and slab members are set lower than those of other members, there are cases in which deteriorations occurring in beams and slabs are not properly reflected in the floor level evaluation. In this study, to overcome such limitations, case studies were carried out and modified importance factors for structural member types were proposed considering the failure probabilities of each member type based on the reliability theory. The importance modification factor was calculated based on the strength ratio of structural members so that the more dangerous the members are, the more impact they give on the evaluation. Overall, compared to the KISTEC method, the proposed method provided conservative but practical assessment results, and it was found that the proposed importance factors can be very useful to properly reflect the effects of damaged members on the deterioration status evaluation of the floors and the entire structure.

뉴로-퍼지 시스템을 활용한 철근콘크리트 패널의 전단거동평가모델

조해창,이득행,황진하,주현진,김강수,서수연 대한건축학회지회연합회 2013 대한건축학회연합논문집 Vol.15 No.1

철근콘크리트 부재의 전단전달 매커니즘이 매우 복잡하기 때문에 이론적 접근방법이 매우 어렵고 많은 불확실성을 내포하고 있다. 이러한 이유로 설계기준들을 포함한 여러 연구들에서는 대부분 반경험적으로 결정된 전단강도 평가식을 사용하고 있으며, 철근콘크리트 부재의 전단거동에 대한 이해 및 접근 방법은 더욱 제한적이다. 따라서, 이 연구에서는 발전된 뉴로-퍼지 정보시스템(Neuro-Fuzzy information system)인 ANFIS (Adaptive nuero-fuzzy inference system)를 철근콘크리트 패널부재의 전단거동평가에 도입하였으며, 역전파알고리즘을 통하여 전단저항 메커니즘이 내포하고 있는 불확실성을 크게 감소시킬 수 있는 ANFIS 해석모델을 도출하였다. ANFIS의 훈련과정을 통하여 최적화된 ANFIS 전단거동해석모델에 의한 해석결과와 실험결과와의 비교를 통하여 분석한 결과, 제안모델은 패널 실험체들의 전단거동을 매우 근사하게 모사하였으며, 균열전 탄성거동, 전단균열강도, 균열후 거동, 극한강도 뿐만 아니라 일부 실험체들에서 관측된 최대강도이후의 연화거동도 잘 평가하는 것으로 나타났다.

ANFIS를 활용한 UHPC 휨부재의 전단강도 평가

조해창,박민국,김민수,한선진,김강수 대한건축학회지회연합회 2018 대한건축학회연합논문집 Vol.20 No.1

For safe design of the reinforced concrete flexural members cast with Ultra High Performance Concrete (UHPC), their shear strengths shall be estimated accurately. Many studies have been performed on the shear strengths of UHPC flexural members so far, but it is still very challenging to estimate their shear strengths accurately because they are considerably influenced by various factors. In this study, an Adaptive Neuro-Fuzzy Inference System (ANFIS) was introduced to estimate their shear strengths, and trained by the test data collected from previous studies. The analysis results by the trained ANFIS algorithm were compared with those calculated by Association Francaise de Genie Civil (AFGC) and Japan Society of Civil Engineers (JSCE) Recommendations, and the ANFIS model provided much better accuracy with an average of 0.98 and a COV of 0.15 than the code provisions. 초고성능콘크리트(UHPC) 휨부재의 안전한 설계를 위해서는 전단강도에 대한 정확한 평가가 필요하다. 지금까지 UHPC 휨부재의 전단강도에 대한 많은 연구가 수행되었지만, 전단강도가 다양한 인자들에 의하여 영향을 받기 때문에 아직도 UHPC 휨부재의 전단강도를 정확하게 평가하는 것은 매우 어렵다. 이 연구에서는 UHPC 휨부재의 전단강도를 평가하기 위하여 뉴로-퍼지추론 시스템(ANFIS)을 도입하고 기존 실험결과를 수집하여 ANFIS를 훈련시켰다. 훈련된 ANFIS 알고리즘을 통하여 해석된 결과를 프랑스 토목학회(AFGC-SETRA)와 일본 토목학회(JSCE) 설계기준식에 의하여 산정된 결과와 비교하였으며, ANFIS 모델은 평균 0.98, COV 0.15으로써 기준식들에 비해 매우 우수한 정확도를 나타내었다.

경상남도 진양호 (晋陽湖) 주변의 담수 패류 분포 및 서식환경 조사

조해창,정평림,장재경,이근태 한국하천호수학회 1985 생태와 환경 Vol.18 No.1·2