골반경하에 처치한 난소임신 1 예

조장철(JC Cho),서성진(SJ Seo),두재균(JK Doo) 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.4

저자 등은 최근 본원 산부인과에서 비교적 잘 보존된 난소의 임신 1 예를 경험하였고 골반경수술을 이용하여 치료하였기에 간단한 문헌 고찰과 함께 보고하는 바이다. Ovarian pregnancy is one of the rarest types of extrauterine pregnancy, which is difficult to diagnose clinically and even intraoperatively. Clinical presentations of ovarian and tubal pregnancies are similar and differentiation can be made only after microscpic examination of tissue specimens. Ovarian pregnancy occurs within the ovary and on the corpus luteum, usually with rupture of the ovary and a massive hemoperitoneum. We report a relatively intact ovarian pregnancy with laparoscopic removal with a brief review of the literatures.

그레이브스병에 있어서 항갑상선제와 티록신 병합요법의 효과

조장현(Jang Hyun Cho),오기창(Ki Chang Oh),김명원(Myung Won Kim),김원석(Won Seok Kim),추진호(Jin Ho Choo),조형철(Hyung Cheol Cho),김순호(Soon Ho Kim),임중규(Joong Kyu Lim),허진득(Jin Duk Huh) 대한내과학회 1998 대한내과학회지 Vol.54 No.2

N/A Objectives: It was recently reported that the administration of T during antithyroid drug(ATD) therapy resulted in a significant decrease of antibodies to TSH receptors as well as the rate of recurrence of active Graves' disease following discontinuance of ATD treatment. But, there is still controversy whether combination therapy is efficient. Therefore, the present study was undertaken to evaluate the effect of T4 administration of patient with Graves' disease who were being treated with ATD. Methods: We studied 56 patients received methimazole(MMI) alone(Group 1) and 48 patients received methimazole plus T4(Group 2). They are diagnosed active Graves' disease at department of internal medicine, Kwang ju Christian Hospital from January, 1994 to December, 1995. AU the patients were treated initially with 30mg of methimazole daily for one month after then, in the Group 1(methimazole alone), the dose of methimazole was adjusted as necessary to achieve normal serum concentrations of T3, T4, and TSH. The patients of Group 2(methimazole plus T4) continue to receive the combination of T4 at a dose of 100 μg daily. Simultaneously, we estimated the serum concentratio n of T3, T4, TSH and Thyroid-stimulating immunoglob ulin(TSI) antibody at every three months. Results : We obtained the following result. In the group 1, mean TSI values were 50.1%(first visit), 30.6%(6months), and 24.7%(1year). And, in the group 2 mean TSI values were 51.8%(first visit), 33.6%(6months), and 22.7% (1year). After 6 months of discontinuing of therapy, the recurrence rate was no significant difference in the two groups (the recurrence rate were 55.4%, 50.0%, respectively P>0.05). Conclusion : These results suggest that T4 administration in combination with MMI therapy have no significant effect in a decrease in levels of TSH receptors antibodies and recurrence rate within 6 months discontinuing MMI therapy as compared with MMI treatment alone.

춘계학술대회 : 포스터전시 ; 간세포암종 환자에서 사이버나이프 치료의 효과와 안전성: 예비연구

이상대,박수철,한철주,조장현,이석영,김진,김유철,김미숙 대한간학회 2007 Clinical and Molecular Hepatology(대한간학회지) Vol.13 No.3(S)

재발된 멕켈-그루버 증후군 1예

진소자,조장철,정영주 의과학연구소 2000 全北醫大論文集 Vol.24 No.2

The Meckel-Gruber Syndrome is a condition of multiple congenital abnormalities with an occipital encephalocele, polydactyly and polycystic kidney disease with some other variable features. The condition is considered invariably fatal with an autosomal recessive pattern of transmission, a 25% recurrence risk. We experienced a rare case of Meckel-Gruber syndrome in a woman who had one affected off-spring in the past with similar condition. Antenatal ultrasonographic diagnosis and management were presented.

구연 : 간세포암종에 대한 AP (doxorubicin-cisplatin) 감량요법의 효과: 다기관 공동연구

이호진,한철주,박수철,조장현,백순구,김영석,김동준,황성규,김연수,이준성,황재석,연종은,김형준 대한간학회 2009 Clinical and Molecular Hepatology(대한간학회지) Vol.15 No.3(S)

경피경간적 담도내시경법에 의한 폐쇄성 담도질환의 진단 및 치료

김명원,박홍배,여향순,추진호,조형철,조장현,김원석,오기창,강명원,임연근 대한소화기내시경학회 1998 Clinical Endoscopy Vol.18 No.1

Background/Aims: Obstructive jaundice is developed from the cholangiocarcinoma, biiliary tract stone, biliary benign stricture and pancreatic head cancer and is rapidly progress to cholangitis or sepsis. So early decompression, accurate diagnosis and treatment are very important. Percutaneous transhepatic choledocoscopy(PTCS) and endoscopic retrograde choledocoscopy(ERCS) have been used for evaluation of the obstructive jaundice. We performed, through the PTCS, electrohydraulic lithotripsy(EHL) for biliary tract stone rernoval, biopsy for diagnosis of biliary stric and self expandible metalic coil stent(EndocoilTM stent, Instent Co.) insertion on biliary stricture to evaluate the usefullness of PTCS in patients with obstructive jaundice. Methods: Between Auguest 1994 and September 1995, PTCS was performed in 37 patients with obstructive jaundice. First, percutaneous transhepatic biliary drainage(PTBD) with 7Fr. drainage tube was done. Three days later, we exchainged the 7Fr. drainage tube with 16Fr.. Seven days later, through the PTCS, we performed EHL, biopsy and EndocoilTM stent insertion. Results: 1) Stones were removed completely and patients were imprcaved clinically after PTCS with EHL in 17 patients with biliary tract stone. During one year, anyone of these patients were not recurred. 2) Biopsy was done in 13 patients with biliary stricture and then 7 patients were confirmed as CBD cancer. 3) EndocoilTM insertion was performed in 22 patients with biliary stricture. In one patient, EndocoilTM iltsertion was failed due to too lowerly inserted. During one year, only 4 patients developed biliary tract obstruction. Conclusion: These resuts suggest that, through the PTCS, EHL of biliary tract stones, biopsy and EndocoilTM stent insertion on biliary stricture are very useful method for biliary tract decompressiom, accurate diagnosis and treatment of patients with obstructive jaundice.

양성 단일 갑상선 결절의 갑상선 호르몬 억제요법

김순호,오기창,추진호,임중규,조형철,조장현,허진득 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.1

Background: Clinically apparent thyroid nodule is a very common disease in adults. Patients are often treated with thyroxine in order to reduce the size of the nodule, but the efficacy of thyroxine-suppressive therapy with thyroxine remains uncertain. We investigated the efficacy of thyroxine-suppressive therapy and the hormonal characteristics during thyroxine therapy to find out whether such measurement could be used to determine the effectiveness of this therapy in patients with benign solitary thyroid nodule proved by aspiration biopsy. Methods: In this study, 54 patients were randomly assigned to receive L-thyroxine(Group I, n=24) or placebo(GroupII, n=30) for 1 year. High resolution ultrasonography(10MHz) was used to measure the size of the nodules at six month intervals. Thyroid hormones and thyroglobulin assay and FNA(fine needle aspiration) was done at the same time. The dose of thyroxine was 200ug/day. Patients were followed at 6 month intervals. Results: The results were as follows: 1) 13(54.1%) out of 24 Group I patients after adequate TSH suppression had a statistically significant reduction of nodule size and before-to-after nodule volume ratios were significantly different between the Group I and Group II patients. 2) In the responders among Group I patients, the before-to-after therapy ratio of the nodule volume was not related to the pretreatment nodule size, thyroid hormones and thyroglobulin levels. Conclusion: Thus we concluded that an adequate suppressive dose of L-thyroxine significantly altered the volume of the benign solitary thyroid nodules 12 months later. ( J Kor Soc Endocrinol 12:45-52, 1997)

담낭절제술후의 내시경적역행성담췌관조영술의 진단소견과 치료

김원석(Won Seok Kim),조형철(Hyung Chul Cho),조장현(Jang Hyun Cho),추진호(Jin Ho Chu),김명원(Myung Won KIm),오기창(Ki Chung Oh),강명원(Myung Won Kang),임연근(Yun Kun Lim),여향순(Hyang Soon Yeo),박홍배(Hong Bae Park) 대한내과학회 1998 대한내과학회지 Vol.54 No.5

N/A Objectives: Accurate assessment of the retained or recurrent bile duct stone is important in postcholecys-tectomy patients who have signs of cholangitis or other pancreatobiliary disease. This study was performed to evaluate the diagnostic and therapeutic reliability of endoscopic retrograde cholangiography in posteholecystectomy patients. Methods: From October 1975 through August 1995, we reviewed 311 patients retrospectively who had undergone on cholecystectomy, Our study was based on assessment of their age, sex, symptoms and physical findings, comparison between sonographic and endoscopic retrograde cholangiographic findings, and stone removal rate using endoscopic sphincterotomy, basket, electrohydraulic lithotripsy. Results: The ratio of male to female was 1:1.67, and the mean age was 56±14.3 years. After cholecystectomy, they visited our clinic within 2 years in 25 patients (8.4%), beyond 2 years in 286 patients (91.6%). Most common symptoms and physical findings were epigastric pain or tenderrs (63.6%). We detected bile duct stone using endoscopic retrograde cholangiography 219 patients. In case of the bile duct stone, we successfully removed it using endoscopic sphincterotomy, basket, electrohydraulic lithotripsy in 194 patients (88.6%). Conclusion: From the above results, we concluded that endoscopic retrograde cholangiography was the most effective diagnostic and therapeutic method in postch-olecystetomy patients who have signs of cholangitis.

기관투자자 거래와 IPO 이후 주가성과

박진우(Jin Woo Park),정규철(Gyu Chul Jung),조장은(Jang Eun Cho) 한국증권학회 2016 한국증권학회지 Vol.45 No.1

본 논문에서는 2003년부터 2012년까지 유가증권시장과 코스닥시장에 신규 상장된 기업을 대상으로 기관투자자의 매매패턴이 IPO 주식의 장기 주가성과에 미치는 영향을 분석하고 있다. 분석한결과를 요약하면 다음과 같다. 첫째, 기관투자자가 IPO 주식에 대해 상장 이후 21거래일(약 1개월)동안 평균적으로 공모주식수의 20% 이상을 순매도하고 있고, 대부분이 첫 거래일과 이후 이틀동안에 집중되고 있다. 둘째, 상장 이후 21일 동안 기관투자자의 누적순매수비율에 따라 구성된5개 포트폴리오의 투자성과를 보면, 누적순매수비율이 가장 큰 포트폴리오와 가장 작은 포트폴리오의1년 보유기간초과수익률 평균값의 차이가 7% 이상을 나타내며 기관투자자가 유리한 매매패턴을 통해 우월한 투자성과를 보여주고 있다. 셋째, 다중회귀분석을 통해 분석한 결과, 다른 변수들을 통제한 이후에도 기관투자자의 누적순매수비율이 IPO 이후 주가성과에 유의한 양(+)의 값을 보이며 기관투자자가 많이 순매도한 IPO 주식일수록 투자성과가 낮다는 것을 확인할 수 있다. 넷째, 기관투자자를 금융투자, 투신, 연기금, 보험, 은행, 기타금융, 사모펀드, 국가기관 등 8가지 유형으로 분류하여 기관투자자의 누적순매수비율과 IPO 이후 주가성과와의 관계를 분석한 결과에서는 기관투자자의 유형에 따라 다소의 차이를 보여주고 있다. 끝으로, 기관투자자의 매매패턴 결정요인에 관한 분석에서는 초기수익률이 높고 변동성이 큰 IPO 주식일수록 기관투자자의 순매도가 크게 나타나고 있다. 이와 같은 연구결과는 정보비대칭이 심각한 IPO 시장에서 상대적인 정보우위에 있는 기관투자자가 유리한 매매패턴을 통해 우월한 투자성과를 보이고 있음을 시사하고 있다. This paper examines the impact of institutional investor trading on the investment performance of IPO stocks listed on the Korea Exchange (KRX) during the period from 2003 to 2012. The results are summarized as follows. First, on average more than 20% of offering shares are sold by institutional investors within one month following IPOs. In particular, the net selling of institutional investors concentrates for the first few days of IPOs. Second, in the examination of quintile portfolios that are composed by the cumulative net buying ratio of institutional investors within one month following IPOs, 1-year BHAR (buy-and-hold abnormal return) of the highest portfolio (Q5) is larger than that of the lowest portfolio (Q1) by more than 7%. This result suggests that smart money effect of institutional investors exists in the Korean IPO market. Third, the cross-sectional regression result also confirms that the net buying ratio of institutional investors has a significantly positive impact on the 1-year BHAR of IPO stocks. Fourth, in the investigation of the institutional investors that are classified into eight groups including investment trust companies, securities companies, banks, insurance companies, pension funds, private equity funds, national institution, and others, we find that the results are somewhat mixed. Finally, we find that the initial returns and volatility of IPO stocks are significant determinants of the trading pattern of institutional investors.

폐경기 여성에서 호르몬 대체요법에 따른 삶의 질에 대한 평가

김종덕,김주영,류철희,정소망,조장철,임승현 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.9

목적: 최근 평균수명의 연장에 따른 삶의 양적증가와 더불어 삶의 질적 향상에 대한 관심이 고조되고 있다. 특히, 호르몬 대체요법이 폐경기여성에 있어서 삶의 질을 향상시킨다는 많은 보고들이 발표되고 있다. 이에 저자는 폐경기여성의 삶의 질에 대한 평가도구의 하나인 WHQ를 이용하여 호르몬 대체요법에 따른 삶의 질 향상유무를 평가하고자 하였다. 연구 방법: 1997년 1월부터 4월까지 폐경증상이나 골다공증을 주소로 내원한 여성을 대상으로 호르몬 대체요법을 받은 여성과 받지않은 여성을 각각 20명씩 무작위 선정하여 내원 당시, 그 후 3개월과 6개월에 WHQ로 평가하였다. 결과: WHQ 각 항목별 시간에 따른 증상의 변화를 살펴보면, 치료군에 있어서 성기능과 월경항목을 제외한 모든 항목에서 개선되는 결과를 얻었고 대조군에서는 변화가 없었다. 결론: 폐경기 여성에 있어서 호르몬 대체요법은 폐경증상의 개선과 함께 삶의 질을 향상시키는 것으로 사료되었다. Objective: The aim of the present study was to assess the effect of hormone replacement therapy by focusing on aspects of quality of life in menopausal women. Methods: We conducted a study on patients with symptoms of menopause or osteoporosis for a three-month period in 1997, from January to April. We randomly selected a case group and a control group. And we conducted three WHQ surveys on these two groups at interval of three months. The first survey on their first visit, the second after 3 months and then the third after 6 months. Statistical analyses included t-test, χ2-test end ANOVA. Results: Evaluating each item on WHQ surveyed at three different times, we observed that all the rest of the these items were improved in the case group while there was no change in the control group except for the items of sexual function and menstruation. Conclusion: The hormonal replacement therapy has considerably improved the symptoms of menopause. Therefore, we should promote liberally the use of the hormonal replacement therapy and counsel women about the menopause and an indivisualized therapy.