회장 말단부 폐쇄를 동반한 호산구성 위장관염 1예

조심현,이정화,백봉력,박원일,신영민,윤상조,이상무 대한내과학회 2002 대한내과학회지 Vol.63 No.6

Eosinophilic gastroenteritis is a rare clinicopathologic entity of an unknown etiology with a variety of digestive symptoms. The clinical features depend on the site of eosinophilic infiltration and affected layer of intestinal wall. Diagnostic criteria include demonstration of eosinophilic infiltration of the affected bowel wall, lack of evidence extra-intestinal disease, and exclusion of various disorders that could mimic similar conditions. We experienced a 54-year-old man with 6 months history of severe intermittent abdominal colic associated with malnutrition and weight loss. Abdominal computed tomography showed mass like lesion at terminal ileum, which caused partial small bowel obstruction. So, we carried out laparotomy, and then segmental resection and ileo-ascending colostomy were done because of small bowel obstrucion. We diagnosed the case as transmural type of eosinophilic gastroenteritis. We report this case with a brief review of the literatures.

한국식 초저열량 식이요법의 비만치료 효과

박원일,이종협,조심현,백봉력,최충경,이성근,문한규,최영미,정윤석,이관우,김현만,김미경,이지현,최선정 대한내과학회 2002 대한내과학회지 Vol.62 No.3

목적 : 비만치료에 사용되는 초저열량 식이요법을 전통적인 한국음식으로 제공하여 그 안전성 및 치료 효과를 관찰하였다.대상 및 방법 : 1998년 5월부터 1998년 12월까지 동의 의료원 내과에 입원한 비만환자 12명을 연구 대상자로 선정하였다. 한국식 초저열량 식이는 14일간 다음과 같은 일정에 의해 제공되었다. 즉, 일일 1200 Kcal, 1000 Kcal, 710 Kcal, 450 Kcal, 710 Kcal, 1000 Kcal를 각각 2일, 2일, 2일, 10일, 2일 및 2일 동안 순서에 따라 제공하였다. 연구대상자들의 신장, 체중, 혈중 지질, 혈중 인슐린 농도, 체성분, 체지방을 식이요법 전후에 측정하였다. 결과 : 초저열량 식이요법 후 체성분의 변화는 체중은 83.8 kg에서 78.6 kg으로, 제지방 체중은 51.6 kg에서 50.0 kg으로, 체지방은 32.2 kg에서 28.6 kg으로, 체질량 지수는 31.4에서 29.5로 모두 유의하게 감소하였다 (p<0.05). 복부 전산화 단층촬영에서 단일 사진 면적당 총 지방량은 807 cc에서 659 cc로, 피하지방은 567 cc에서 473 cc로, 내장지방은 273 cc에서 185 cc로 모두 유의한 감소가 있었다 (p<0.05). 그러나 혈청 전해질 농도의 유의한 변화는 없었다. 식사요법 후 총 콜레스테롤이 199 mg/dL에서 166 mg/dL로, 고밀도지단백-콜레스테롤은 42 mg/dL에서 35 mg/dL로, 중성지방이 158 mg/dL에서 75 mg/dL로 유의하게 감소하였다 (p<0.05). 혈중 인슐린-곡선하 면적 (insulin-area under the curve)도 식이요법 전 205 μIU/mL·2hr에서 식이요법 후 168 μIU/mL·2hr로 유의한 감소가 있었다 (p<0.05). Background : There is increasing interest in the use of a very low calorie diet (VLCD) as a treatment regimen for weight loss in obese subjects. This study was designed to investigate the effects and safety of a traditional Korean very-low-calory diet Methods : Twelve hospitalized obese patients at Dong Eui hospital in Busan city from May 1998 to December 1998 were selected. Height, body weight, blood lipids, blood insulin level, body fat, lean body mass, subcutaneous fat and visceral fat were measured. A traditional Korean VLCD was supplied for 14 days. Results : Patient's body weight was significantly decreased from 83.8 kg to 78.6 kg, body fat from 32.2 kg to 28.6 kg, lean body mass from 32.2 kg to 28.6 kg, and BMI from 31.4 to 29.5, respectively (p<0.05). Total fat was significantly decreased from 807 cc to 659 cc, subcutaneous fat from 567 cc to 473 cc, visceral fat from 273 cc to 185 cc, respectively. However there were no significant changes in minerals. After VLCD intervention, total cholesterol was significantly decreased from 199 mg/dL to 166 mg/dL, HDL-cholesterol from 42 mg/dL, to 35 mg/dL, triglyceride from 158 mg/dL, to 75 mg/dL (p<0.05). The insulin area under the curve was also significantly decreased from 205 μIU/mL․2hr to 168 μIU/mL․2hr (p<0.05). Conclusion : Above findings suggested that a traditional Korean VLCD is effective and safe for short term use in terms of reducing body fat and improving insulin resistance in obese patients.(Korean J Med 62:250-257, 2002)

말기 위암 환자에서 발생한 분선충 중감염 1예

백봉력,이정화,조심현,박원일,박영래,윤상조,장원익,문한규,정소영,홍재락,송수복 대한내과학회 2002 대한내과학회지 Vol.62 No.2

Strongyloides stercoralis is an intestinal nematode which infects a large portion of the world's population especially in tropical areas and other hot, humid regions. Because of an opportunistic nature of the parasite, the infection is confined to the intestinal tract in immunocompetent hosts. But, in individuals having immunocompromised state, the parasite is augmented by autoinfection, resulting in hyperinfection and/or systemic dissemination. In Korea, several cases of strongyloides hyperinfection were reported since 1959, especially who had corticosteroid therapy and other immunosuppressive medications. We experienced a case of strongyloides hyperinfection, accompanied with terminal stage of stomach cancer. The patient responded to treatment with albendazole. After one month later, repeated follow-up stool exam revealed clearance of the larvae from the patient' feces. So, we report this case with the literature.(Korean J Med 62:230-233, 2002) 저자들은 말기 위암으로 건강상태가 쇠약한 71세의 남자환자로부터 얻어진 대변검사에서 많은 수의 분선충의 유충 및 성충을 발견하였으며, albendazole 400 mg을 2회로 나누어 3일간 경구 투여 하였다. 1개월 후에 실시한 대변 검사상 분선충의 유충 및 성충은 더 이상 발견되지 않았으며, 이를 문헌 고찰과 함께 보고하는 바이다.

포스터 전시 발표 : 알레르기,류마티스 ; 류마티스 관절염에 동반된 결절성 근막염(Nodular fasciitis) 1예

이종협,김채규,이준상,조심현,이정화,김상현,김종현,황정업 대한내과학회 2003 대한내과학회 추계학술대회 Vol.65 No.10

말기 위암 환자에서 발생한 분선충 중감염 1 예

정소영,이정화,박원일,문한규,박영래,송수복,백봉력,조심현,윤상조,장원익,홍재락 대한내과학회 2002 대한내과학회지 Vol.62 No.2

Strongyloides stercoralis is an intestinal nematode which infects a large portion of the world's population especially in tropical areas and other hot, humid regions. Because of an opportunistic nature of the parasite, the infection is confined to the intestinal tract in immunocompaetent hosts. But, in individuals having immunocompromised state, the parasite is augmented by autoinfection, resulting in hyperinfection and/or systemic dissemination. In Korea, several cases of strongyloides hyperinfection were reported since 1959, especially who had corticosteroid therapy and other immunosuppressive medications. We experienced a case of strongyloides hyperinfection, accompanied with terminal stage of stomach cancer. The patient responded to treatment with albendazole. After one month later, repeated follow-up stool exam revealed clearance of the larvae from the patient' feces. So, we report this case with the literature.(Korean J Med 62:230-233, 2002)

한국식 초저열량 식이요법의 비만치료 효과

박원일(Won Il Park),이종협(Jong Hyup Lee),조심현(Shim Hyun Jo),백봉력(Bong Luck Paik),최충경(Chung Keung Choi),이성근(Seung Geun Lee),문한규(Han Kyu Moon),최영미(Young Mee Choi),정윤석(Yoon Sok Jung),이관우(Kwan Woo Lee),김현만(Hyeon 대한내과학회 2002 대한내과학회지 Vol.62 No.3

N/A Background: There is increasing interest in the use of a very low calorie diet (VLCD) as a treatment regimen for weight loss in obese subjects. This study was designed to investigate the effect s and safety of a traditional Korean very-low-calory diet Methods: Twelve hospitalized obese patients at Dong Eui hospital in Busan city from May 1998 to December 1998 were selected. Height, body weight, blood lipids, blood insulin level, body fat, lean body mass, subcutaneous fat and visceral fat were measured. A traditional Korean VLCD was supplied for 14 days. Results: Patient's body weight was significantly decreased from 83.8 kg to 78.6 kg, body fat from 32.2 kg to 28.6 kg, lean body mass from 32.2 kg to 28.6 kg, and BMI from 31.4 to 29.5, respectively (p <0.05). Total fat was significantly decreased from 807 cc to 659 cc, subcutaneous fat from 567 cc to 473 cc, visceral fat from 273 cc to 185 cc, respectively. However there were no significant changes in minerals. After VLCD intervention, total cholesterol was significantly decreased from 199 mg/dL to 166mg/dL, HDL-cholesterol from 42 mg/dL, to 35mg/dL, triglyceride from 158mg/dL, to 75mg/dL (p<0.05). The insulin area under the curve was also significantly decreased from 205μIU/mL·2hr to 168 μIU/mL·2hr(p <0.05). Conclusion: Above findings suggested that a traditional Korean VLCD is effective and safe for short term use in terms of reducing body fat and improving insulin resistance in obese patients. (Korean J Med 62:250-257, 2002)

국소성 근염(Focal myositis)

박영래 ( Young Rae Park ),박원일 ( Won Il Park ),백봉력 ( Bong Luck Paik ),조심현 ( Sim Hyun Jo ),이정화 ( Jung Hwa Lee ),이경신 ( Kyung Sin Lee ),김채규 ( Chae Kyu Kim ) 대한류마티스학회 2001 대한류마티스학회지 Vol.8 No.4

Focal myositis, a benign inflammatory pseudotumor of skeletal muscle, which was first described on a series of 16 patients by Heffner et al. in 1977. It may occur at any time from early childhood into the seventh decade, most commonly in adults, with an equal sex incidence. It is most commonly seen in the lower extremities. The etiology is unknown. Histologic features are similar to those seen in inflammatory myopathy, including muscle cell necrosis, regeneration and lymphocyte infiltration. The diagnosis can be confirmed only by biopsy and in all cases histologic features of inflammatory myopathy are observed. We report a case of focal myositis that appeared as pseudotumor.