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111In-Pentetreotide 스캔으로 진단 가능했던 가스트린종을 가진 Zollinger-Ellison 증후군 1예
정훈용,문대혁,류진숙,이희경,김재승,하현권,정현조 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.6
In patient with Zollinger-Ellison syndrome, it is difficult to localize gastrinoma because the tumor is frequently small and multiple. However, accurate localization of the tumor is important for the treatment. Among various imaging modalities, somatostatin receptor scintigraphy (SRS) has been recognized to be the most sensitive tool for the detection of neuroendocrine tumors such as gastrinomas based on the presence of high-affinity binding sites for somatostatin. Recently, we experienced a case of Zollinger-Ellison syndrome caused by gastrinomas which was localized by SRS. This is the first case report of gastrinoma detected by SRS in Korea. SRS can facilitate tumor detection in patient with Zollinger-Ellison syndrome and should be considered as the first-line diagnostic method in the early course of the disease.
정훈용,조상헌,조영주,민경업,김유영,이건국,지제근 대한천식알레르기학회 1990 천식 및 알레르기 Vol.10 No.2
Allergic granulomatosis and angiitis is a disorder characterized by hypereosinophilia and systemic vasculitis occurring in individuals with asthma and allergic rhinitis The histopathologic findings are necrotizing vasculitis, tissue infiltration by eosinophils and extravascular granulomas. A case of allergic granulomatosis and angiitis is presented with a discussion of its clinical and pathological manifestations. Diagnosis of this case as allergic granulomatosis and angiitis is supported by a characteristic clinical presentation of skin rashes, hypereosinophilia and asthmatic background with histopathologic picture that consists of a necrotizing arteritw with heavy eosinophilic infiltration.