양막 콘텍트렌즈의 임상적 효용성

정현철,이재훈,최수영,김성포,박완기,박우찬 대한안과학회 2022 대한안과학회지 Vol.63 No.7

목적: MS-Amnion 양막 콘택트렌즈의 임상적 효용성에 대해 알아보고자 하였다. 대상과 방법: 비수술적 치료에 반응하지 않는 심한 점상각막염 또는 각막상피결손 환자를 대상으로 MS-Amnion 양막 콘텍트렌즈를1주일 동안 착용하였다. 3개월 이상 경과 관찰한 18안을 대상으로 시술 전과 시술 후 시력, 눈물막파괴시간, 각막지각과 각막혼탁정도를 비교하였으며, 경과 관찰 기간 중 치료 성공률 및 병변 재발률과 기타 합병증에 대해 분석하였다. 결과: 18안 중 15안(83.3%)은 2주 이내에 병변이 호전되어 추가 양막 치료 없이 회복하였고, 3안(16.7%)은 치료 이후에도 병변이 지속되어 추가적인 양막이식술을 하였다. 회복되었던 15안 중 3안(20%)은 기존 병변이 재발하였다. 양막 콘택트렌즈 착용 기간 동안 5안(27.8%)은 양막이 저절로 탈락했고, 2안(11.1%)은 반으로 접혀 있었다. 최대교정시력은 시술 전 평균 0.89 logarithm of the minimal angle of resolution (logMAR)에서 3개월 후 0.27 logMAR로 호전되었고, 각막혼탁 정도는 시술 전 평균 0.38에서 3개월 후 0.11로감소하였으며 두 수치는 통계적으로 유의한 차이를 보였다. 눈물막파괴시간과 각막지각은 호전되는 양상을 보였으나 통계적으로 유의한 차이는 없었고, 특별한 합병증은 발견되지 않았다. 결론: MS-Amnion 양막 콘택트렌즈는 봉합사를 이용한 일시적 양막이식술과 달리 외래에서 간편하게 적용할 수 있는 장점이 있고, 난치성 안구 표면 질환을 치료하는 데 있어 일시적 양막이식술을 대체할 수 있는 효과적인 방법이 될 수 있을 것이라 기대된다.

호도약침(胡桃藥鍼)이 Glycerol로 유발(誘發)된 급성신부전(急性腎不全) 백서(白鼠)의 이뇨(利尿)에 미치는 영향(影響)

정현철,송춘호,Jung, Hyun-Chol,Song, Choon-Ho 대한침구의학회 2000 대한침구의학회지 Vol.17 No.1

This study was undertaken to determine if Juglandis Semen Aquacupuncture(Ja) has a protective effect against glycerol-induced acute renal failure in rats. Rats were dehydrated for 24hr and then injected with $5m{\ell}/kg$ of 50% glycerol, one-half of dose in each hindlimb muscle. In experiments for Ja effect, rats received $0.1m{\ell}$ of Ja extraction in both sides of corresponding $Sh{\grave{e}}ns{\bar{u}}$($BL_{23}$) of human body and non-acupuncture points(the root of tail) for 3 days after injection of glycerol. The experimental group were divided into the Normal group, the Control group, the Ja to $Sh{\grave{e}}ns{\bar{u}}$($BL_{23}$) group(Ja-AS), the Ja to non-acupuncture points group(Ja-AN). There were significant decrease of Urine vollume, total protein and phosphate level in Ja-AS as compared with the control group. There were not any significant change of Urine creatinine in Ja-AS as compared with the control group. There were significant decrease of Unine glucose in Ja-AS, Ja-AN as compared with the control group. This suggests that Ja-AS could be used in prevention and treatment of acute renal failure. However, the precise mechanisms of Ja protection remain to be determined.

행-열 효과모형에 대한 고찰

정현철 평택대학교 1998 論文集 Vol.11 No.-

본 연구에서는 순위변수를 가지는 범주형자료분석으로 Anderson(1980)과 Goodman(1979)등에 의해 연구된 선형 대 선형 연관모형(Linear-by-Linear association model)을 토대로 하여, 선형 대 선형 연관모형보다 일반화된 모형인 행-열 효과모형(Row and Column effect model)을 소개하고, 이와 관련성을 지니는 범주형자료에 대한 상관모형(O'Neill, 1978)과 대응분석 그리고 수량화 3법과의 관계성을 살펴보고자 한다. 또한 Davis(1988)의 행-열 효과모형의 SAS Macro 알고리즘을 소개하고 사례분석을 통하여 행-열 효과모형의 활용성을 고찰하고자 한다.

장방형내 저온 단일 수평 원관 주위의 동결현상에 관한 실험적 연구

정현철,윤재원,장원택,전승배,이동석,김병철 朝鮮大學校 機械技術硏究所 2007 機械技術硏究 Vol.10 No.1

An experimental study on water in a rectangular cavity with a horizontal cooling tube was carried out to investigate the flow character and thermal behavior in the system. Each experiment was performed with variation of initial temperature and cooling tube temperature. When the cooling tube temperature was -4℃, the supercooling phenomenon was observed regardless of the initial water temperature. And the case of cooling tube temperature was -6℃ with initial temperature was below 4℃, the supercooling phenomenon was also observedin the large region of the test section. When the cooling tube temperature was -10℃, the local region of supercooling phenomenon was observed during the freezing process. And the higher initial temperature was, the higher supercooling degree and the less difference of the ice thickness between upward and downward was observed. It is shown that by controllingthe supercooling phenomena and the cooling tube temperature, it would lead to an increase efficiency of ice making.

과학 창의성 계발을 위한 프로그램 개발 - 이론과 예시를 중심으로 -

정현철,한기순,김병노,최승언 한국지구과학회 2002 한국지구과학회지 Vol.23 No.4

Solvent-Ratio Dependency of Polymorphism of Silver(I) Complexes Containing 1,2,3-Tris(Isoniconitoyloxy)Benzene

정현철,노태환 대한화학회 2019 Bulletin of the Korean Chemical Society Vol.40 No.11

Self-assembly of AgClO4 with 1,2,3-tris(isonicotinoyloxy)benzene (L) in a mixture of ethanol and acetone in a 1:1 volume ratio in refrigerator afforded concomitantly two kinds of thin- and block-shaped colorless crystals consisting of {[Ag(L)]ClO4·0.5CH3CH2OH} n and {[Ag(L)]ClO4·0.5CH3CH2OH·2Me2CO} n, respectively, in a 3:2 ratio. By contrast, self-assembly at room temperature yielded thin crystals exclusively. At 5 °C, in particular, the self-assembly in 3:1 and 1:2 ethanol/acetone solutions yielded thin- and block-shaped crystals, respectively, suggesting that discrimination of the two products can be controlled by the solvent volume ratio and crystallization temperature. The products' crystal structures and physicochemical properties were fully characterized by means of single-crystal X-ray diffraction measurement, thermal analysis, and infrared (IR) data.

체육활동노트를 활용한 중학교 통합체육수업 사례연구

정현철,김대진,정호웅 이화여자대학교 교과교육연구소 2013 교과교육학연구 Vol.17 No.3

This study attempted the development of a theory of integrated physical education by using a physical activity notebook and the examination of its process and effects through practical lessons. The participants were 123 students in 6 classes who used physical activity notebooks in their classes; one representative student was chosen per type (total 4 students) by Quota selection. This integrated form of physical education using physical activity notebooks was carried out based on constructivism. The integration of intra-subjects could record the process of thinking and acquisition resulting from the research activities in the physical education classes. The integration of inter-subjects also could teach related units with respect to all middle school subjects with physical education as the center. The results of this study are as follows. First, the students were able to experience their own reflective thinking by re-finding their traces through the physical activity notebook, and their divergent thinking through various thinking activities. Second, the physical activity notebook allowed the students to create a portfolio which provided customized feedback to teachers and which could be used as a form of evaluation. It was therefore a meaningful feedback strategy for both students and teachers. Third, the students themselves set their goals in their physical activity notebook and tried self-directly and continuously to analyze their physical motions and manage their bodies. As a result of this study, it is suggested that integrated physical education using physical activity notebooks could be practical material for the new physical education curriculum. 본 연구는 체육활동노트를 활용한 통합체육수업의 이론적 틀을 정립하고 그에 따르는 수업을 통한 구체적 실천 과정과 그 효과를 살펴보는 데 목적이 있다. 중학교 6개반 123명을 대상으로 체육활동노트를 활용한 통합체육수업을 운영하였으며 그 중 ‘할당 선택’(Quota selection)을 이용하여 4명의 주제보자를 선정하여 연구를 진행하였다. 체육활동노트를 활용한 통합체육수업은 구성주의에 입각한 교육으로 교과내 통합은 체육시간에 경험하는 탐구적인 활동들의 통합을 중심으로 생각과 습득의 과정을 살펴보았으며 교과간 통합은 체육 교과 중심의 중학교 각 교과군에 관련 단원들을 통합하는 형태로 수업을 진행하였다. 그 결과 세 가지 변화를 살펴 볼 수 있었다. 첫째, 학생들은 자신의 흔적들을 체육활동노트를 통해 재발견하면서 반성적 사고를 경험하게 되었고 다양한 사고요소들의 활동을 통해 확산적 사고를 경험하게 되었다. 둘째, 체육활동노트는 학생과 교사 모두에게 의미 있는 피드백 전략으로 학생에게는 하나의 포트폴리오 형식을 취할 수 있었고 교사는 학생에게 맞춤형 피드백을 제시할 수 있었으며 새로운 평가방법으로도 활용되어질 수 있음을 시사하였다. 셋째, 학생들은 스스로 통합체육수업의 학습목표를 체육활동노트에 설정하고, 자기주도적으로 자신의 목표를 이루기 위해 자신들의 신체 움직임을 분석하고 자기 신체 관리를 위해 노력하는 모습을 끊임없이 보여주었다. 이러한 결과를 토대로 체육활동노트를 활용한 통합체육수업이 새로운 체육교육과정에 실천적 자료가 되기를 기대하는 바이다.

Prenatal sonographic diagnosis of a pericardial cyst

정현철,김광준 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.98 No.-

Pericardial cyst is defined as cystic lesion within the pericardial space. It`s incidence is known as 1 in 100,000 person 1 and only a few cases of prenatal diagnosis have been reported so far. Natural course of this lesion is usually benign, but rare complications such as rupture, cardiac tamponade, compression of adjacent structures may occure. We present a case of prenatally diagnosed pericardial cyst. A 32-year-old woman was referred to our hospital at 20 gestational weeks because of an isolated cyst in the right pericardial space. Ultrasonography showed 7.5 cm sized unilocular simple syst adjacent to the right ventricular wall within the pericardium. RV Ejection fraction was within normal range. As there was no detected blood flow within the structure by Color Doppler assessment, ventricular aneurysm was excluded. During follow-up, normal interval fetal growth was documented. Postnatall echocardiography demonstrated findings consistent with the suspected pericardial cyst. The infant and the mother were discharged in good health on post-operation day 5.

Quantification of Marker Compounds in Cirsium setidens Nakai by HPLC-DAD

정현철,심유신,이영경,최상윤,홍희도,정자용,한명주,조장원 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.6

An effective method of high performance liquidchromatography-diode array detector (HPLC-DAD) wasdeveloped for the simultaneous quantification of twomarker compounds, pectolinarin and pectolinarigenin, inCirsium setidens Nakai, a Korean wild herb. The twomarker compounds of C. setidens were separated on a C18column with a gradient system. The calibration curves ofthe two standard compounds exhibited good linearity (R2>0.9992). The limits of detection (LOD) values of pectolinarinand pectolinarigenin were 0.52 and 0.41 μg/mL, respectively,while their limits of quantification (LOQ) values were 1.57and 1.25 μg/mL, respectively. The relative standarddeviations (RSDs) of the data of the intra- and inter-dayexperiments were less than 1.65 and 2.78%, respectively. The results of the recovery test were 98.06-105.81% withan RSD value of 1.87-3.50%. In conclusion, the results ofvalidation showed that the proposed HPLC method wasuseful for the quantification of the two marker compoundsin C. setidens.

체육활동 노트를 활용 체육통합수업

정현철 한국스포츠교육학회 2011 우리체육 Vol.- No.8